Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Thermosipho africanus TCF52B

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Thermotogales
Under regulation:
- Genes 32
- Operons 3
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -602
Score: 112
Sequence: AATATAGAAAACCAT...
Locus tag: THA_1046
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: THA_1045
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: THA_1044
Name: null
Funciton: Putative xylose isomerase domain protein
Locus tag: THA_1043
Name: cobS
Funciton: Cobalamin synthase
Locus tag: THA_1042
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: THA_1041
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: THA_1040
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: THA_1039
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
THA_1046
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
THA_1045
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
THA_1044
Putative xylose isomerase domain protein
THA_1043
cobS
Cobalamin synthase
THA_1042
cbiP
Cobyric acid synthase
THA_1041
cbiB
Adenosylcobinamide-phosphate synthase
THA_1040
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
THA_1039
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Position: -241
Score: 96.6
Sequence: CTATTTGCAGCAACT...
Locus tag: THA_254
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: THA_255
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
THA_254
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
THA_255
btuC
Vitamin B12 ABC transporter, permease component BtuC
Position: -244
Score: 131.2
Sequence: ATAATGTTAACACCT...
Locus tag: THA_1065
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: THA_1066
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: THA_1067
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: THA_1068
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: THA_1069
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: THA_1070
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: THA_1071
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: THA_1072
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: THA_1073
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: THA_1074
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: THA_1075
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: THA_1076
Name: hemA
Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70)
Locus tag: THA_1077
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: THA_1078
Name: cysG
Funciton: cobA
Locus tag: THA_1079
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: THA_1080
Name: cysG1
Funciton: Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
Locus tag: THA_1081
Name: hemL
Funciton: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
Locus tag: THA_1082
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: THA_1083
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: THA_1084
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: THA_1085
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: THA_1086
Name: THA_1086
Funciton: Putative ATP binding protein
THA_1065
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
THA_1066
cbiX
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
THA_1067
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
THA_1068
cbiD
Cobalt-precorrin-6 synthase, anaerobic
THA_1069
cbiE
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
THA_1070
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
THA_1071
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
THA_1072
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
THA_1073
cbiG
Cobalamin biosynthesis protein CbiG
THA_1074
cbiH
Cobalt-precorrin-3b C17-methyltransferase
THA_1075
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
THA_1076
hemA
Glutamyl-tRNA reductase (EC 1.2.1.70)
THA_1077
hemC
Porphobilinogen deaminase (EC 2.5.1.61)
THA_1078
cysG
cobA
THA_1079
hemB
Porphobilinogen synthase (EC 4.2.1.24)
THA_1080
cysG1
Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
THA_1081
hemL
Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
THA_1082
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
THA_1083
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
THA_1084
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
THA_1085
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
THA_1086
THA_1086
Putative ATP binding protein
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