Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing cbiO gene

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Phylum: Thermotogae
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Thermosipho africanus TCF52B
Position: -244
Score: 131.17
Sequence: ATAATGTTAACACCT...
Locus tag: THA_1065
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: THA_1066
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: THA_1067
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: THA_1068
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: THA_1069
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: THA_1070
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: THA_1071
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: THA_1072
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: THA_1073
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: THA_1074
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: THA_1075
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: THA_1076
Name: hemA
Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70)
Locus tag: THA_1077
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: THA_1078
Name: cysG
Funciton: cobA
Locus tag: THA_1079
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: THA_1080
Name: cysG1
Funciton: Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
Locus tag: THA_1081
Name: hemL
Funciton: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
Locus tag: THA_1082
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: THA_1083
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: THA_1084
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: THA_1085
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: THA_1086
Name: THA_1086
Funciton: Putative ATP binding protein
cobT-cbiX-cbiC-cbiD-cbiE-cbiT-cbiL-cbiF-cbiG-cbiH-cbiJ-hemA-hemC-cysG-hemB-cysG1-hemL-cbiM-cbiN-cbiQ-cbiO-THA_1086 -244 131.2 ATAATGTTAACACCT... THA_1065
Thermosipho melanesiensis BI429
Position: -233
Score: 134.7
Sequence: AATAATAAAACATCT...
Locus tag: Tmel_0695
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Tmel_0696
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: Tmel_0697
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Tmel_0698
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: Tmel_0699
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: Tmel_0700
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Tmel_0701
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Tmel_0702
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Tmel_0703
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: Tmel_0704
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Tmel_0705
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: Tmel_0706
Name: null
Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70)
Locus tag: Tmel_0707
Name: null
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: Tmel_0708
Name: cysG
Funciton: cobA
Locus tag: Tmel_0709
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: Tmel_0710
Name: cysG1
Funciton: Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
Locus tag: Tmel_0711
Name: hemL
Funciton: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
Locus tag: Tmel_0712
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: Tmel_0713
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: Tmel_0714
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: Tmel_0715
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: Tmel_0716
Name: Tmel_0716
Funciton: Putative ATP binding protein
cobT-cbiX-cbiC-cbiD-cbiE-cbiT-cbiL-cbiF-cbiG-cbiH-cbiJ-Tmel_0706-Tmel_0707-cysG-hemB-cysG1-hemL-cbiM-cbiN-cbiQ-cbiO-Tmel_0716 -233 134.7 AATAATAAAACATCT... Tmel_0695