Regulog TPP - Corynebacteriaceae
Regulator type: | RNA regulatory element |
Name: | TPP |
RFAM: | RF00059 |
Regulation mode: | |
Biological process: | Thiamine biosynthesis |
Effector: | Thiamine pyrophosphate |
Phylum: | Actinobacteria |

Member of regulog collections
- By taxonomy - Corynebacteriaceae
- By RNA motif - TPP
- By effector - Thiamine pyrophosphate
- By pathway - Thiamine biosynthesis
Genome | Genes | Operons |
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Corynebacterium glutamicum ATCC 13032 | 13 | 5 |
Corynebacterium efficiens YS-314 | 12 | 4 |
Corynebacterium diphtheriae NCTC 13129 | 11 | 3 |
Corynebacterium aurimucosum ATCC 700975 | 10 | 2 |
Corynebacterium jeikeium K411 | 7 | 1 |
Corynebacterium urealyticum DSM 7109 | 12 | 3 |
Corynebacterium amycolatum SK46 | 5 | 2 |
Corynebacterium kroppenstedtii DSM 44385 | 10 | 3 |
Genes | Function | ||||||||
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CRON 1. | |||||||||
oarX |
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Corynebacterium glutamicum ATCC 13032 Site: position = -166 score = 63.54 sequence = TACTAGTGACACGGG... Gene: cg0825: 3-ketoacyl-(acyl-carrier-protein) reductase (EC 1.1.1.100) |
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Gene: ckrop_1720: 3-ketoacyl-(acyl-carrier-protein) reductase (EC 1.1.1.100) |
3-ketoacyl-(acyl-carrier-protein) reductase (EC 1.1.1.100) |
CRON 2. | |||||||||
thiC |
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Corynebacterium glutamicum ATCC 13032 Site: position = -110 score = 55.87 sequence = AGGCAGTCCCCACGG... Gene: cg1476: Phosphomethylpyrimidine synthase |
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Corynebacterium efficiens YS-314 Site: position = 100 score = 57.43 sequence = CGGCAGTCCCCACGG... Gene: CE1407: Phosphomethylpyrimidine synthase |
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Corynebacterium diphtheriae NCTC 13129 Site: position = -110 score = 55.17 sequence = GTGTCCCCCGCGGGC... Gene: DIP0029: Phosphomethylpyrimidine synthase |
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Corynebacterium aurimucosum ATCC 700975 Site: position = -109 score = 52.9 sequence = TGATACCCCACGGGT... Gene: cauri_1573: Phosphomethylpyrimidine synthase |
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Corynebacterium jeikeium K411 Site: position = -114 score = 39.52 sequence = CACAACCGAACACGG... Gene: jk0855: Phosphomethylpyrimidine synthase |
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Corynebacterium urealyticum DSM 7109 Site: position = -112 score = 58.04 sequence = TACCGAAATACGGGC... Gene: cur_1103: Phosphomethylpyrimidine synthase |
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Corynebacterium amycolatum SK46 Site: position = -121 score = 50.96 sequence = ATTACAAAACCACGG... Gene: CORAM0001_0557: Phosphomethylpyrimidine synthase |
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Corynebacterium kroppenstedtii DSM 44385 Site: position = -106 score = 52.77 sequence = CACGACCCCACGGGA... Gene: ckrop_1709: Phosphomethylpyrimidine synthase |
Phosphomethylpyrimidine synthase |
thiE |
*
Corynebacterium glutamicum ATCC 13032 Site: position = -113 score = 62.55 sequence = ACTTACCCCACGGGT... Gene: cg2236: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
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Corynebacterium efficiens YS-314 Site: position = -113 score = 51.52 sequence = CCAACCCCCACGGGC... Gene: CE1933: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: DIP0030: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: cauri_1574: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: jk0854: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: cur_1104: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
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Gene: ckrop_1710: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
cg0121 |
Gene: cg0121: major facilitator superfamily permease |
Gene: CE0097: major facilitator superfamily permease |
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Gene: jk0853: major facilitator superfamily permease |
Gene: cur_1105: major facilitator superfamily permease |
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major facilitator superfamily permease |
thiO |
Gene: cg2237: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: CE1934: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: DIP0031: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: cauri_1575: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: jk0852: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: cur_1106: Glycine oxidase ThiO (EC 1.4.3.19) |
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Corynebacterium amycolatum SK46 Site: position = -116 score = 57.59 sequence = TACCACGTTCCGCGG... Gene: CORAM0001_1432: Glycine oxidase ThiO (EC 1.4.3.19) |
*
Corynebacterium kroppenstedtii DSM 44385 Site: position = -26 score = 54.19 sequence = ATCGTCGACCTACGG... Gene: ckrop_1717: Glycine oxidase ThiO (EC 1.4.3.19) |
Glycine oxidase ThiO (EC 1.4.3.19) |
thiS |
Gene: cg2238: Sulfur carrier protein ThiS |
Gene: CE1935: Sulfur carrier protein ThiS |
Gene: DIP0032: Sulfur carrier protein ThiS |
Gene: cauri_1576: Sulfur carrier protein ThiS |
Gene: jk0851: Sulfur carrier protein ThiS |
Gene: cur_1107: Sulfur carrier protein ThiS |
Gene: CORAM0001_1431: Sulfur carrier protein ThiS |
Gene: ckrop_1716: Sulfur carrier protein ThiS |
Sulfur carrier protein ThiS |
thiG |
Gene: cg2239: Thiazole synthase |
Gene: CE1936: Thiazole synthase |
Gene: DIP0033: Thiazole synthase |
Gene: cauri_1577: Thiazole synthase |
Gene: jk0850: Thiazole synthase |
Gene: cur_1108: Thiazole synthase |
Gene: CORAM0001_1430: Thiazole synthase |
Gene: ckrop_1715: Thiazole synthase |
Thiazole synthase |
thiF |
Gene: cg2240: Sulfur carrier protein adenylyltransferase ThiF |
Gene: CE1937: Sulfur carrier protein adenylyltransferase ThiF |
Gene: DIP0034: Sulfur carrier protein adenylyltransferase ThiF |
Gene: cauri_1578: Sulfur carrier protein adenylyltransferase ThiF |
Gene: jk0849: Sulfur carrier protein adenylyltransferase ThiF |
Gene: cur_1109: Sulfur carrier protein adenylyltransferase ThiF |
Gene: CORAM0001_1429: Sulfur carrier protein adenylyltransferase ThiF |
Gene: ckrop_1714: Sulfur carrier protein adenylyltransferase ThiF |
Sulfur carrier protein adenylyltransferase ThiF |
thiED-tenA |
Gene: cg1654: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiaminase II (EC 3.5.99.2) |
Gene: CE1591: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiaminase II (EC 3.5.99.2) |
Gene: DIP0035: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: cauri_1292: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: jk0297: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
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Corynebacterium urealyticum DSM 7109 Site: position = -143 score = 50.73 sequence = AATAACGCAAGGGGT... Gene: cur_0377: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiaminase II (EC 3.5.99.2) |
Gene: CORAM0001_1880: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
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Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiaminase II (EC 3.5.99.2) |
thiM |
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Corynebacterium glutamicum ATCC 13032 Site: position = -102 score = 52.11 sequence = AATACTAGGCACGGG... Gene: cg1655: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Corynebacterium efficiens YS-314 Site: position = -95 score = 55.5 sequence = AGAACCAGGCACGGG... Gene: CE1592: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Hydroxyethylthiazole kinase (EC 2.7.1.50) |
CRON 3. | |||||||||
ykoE |
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Corynebacterium glutamicum ATCC 13032 Site: position = -100 score = 51.03 sequence = TTCATAGACACGGGT... Gene: cg1227: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Corynebacterium efficiens YS-314 Site: position = -98 score = 60.62 sequence = CGATATTGCACGGGT... Gene: CE1134: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Corynebacterium diphtheriae NCTC 13129 Site: position = -119 score = 59.37 sequence = TTATAAATCACGGGT... Gene: DIP0951: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Corynebacterium aurimucosum ATCC 700975 Site: position = -166 score = 50.36 sequence = CACATCGTCACGGGT... Gene: cauri_0372: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Corynebacterium urealyticum DSM 7109 Site: position = -108 score = 37.2 sequence = CCGACCAACGCGGGA... Gene: cur_0414: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: CORAM0001_0566: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Corynebacterium kroppenstedtii DSM 44385 Site: position = -163 score = 47.6 sequence = CAGTACTTCGCGGGA... Gene: ckrop_0610: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
ykoD |
Gene: cg1228: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: CE1135: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Corynebacterium diphtheriae NCTC 13129 Site: position = -106 score = 59.46 sequence = CGAGATGCCCGGGTG... Gene: DIP0953: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: cauri_0373: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: cur_0415: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: CORAM0001_0567: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: ckrop_0611: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
ykoC |
Gene: cg1229: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: CE1136: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: DIP0954: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: cauri_0374: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: cur_0416: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: CORAM0001_0568: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: ckrop_0612: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
hmpK |
Gene: cg1230: predicted hydroxymethylpyrimidine kinase |
Gene: CE1137: predicted hydroxymethylpyrimidine kinase |
Gene: DIP0955: predicted hydroxymethylpyrimidine kinase |
Gene: cauri_0375: predicted hydroxymethylpyrimidine kinase |
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Gene: cur_0417: predicted hydroxymethylpyrimidine kinase |
Gene: CORAM0001_0569: predicted hydroxymethylpyrimidine kinase |
Gene: ckrop_0613: predicted hydroxymethylpyrimidine kinase |
predicted hydroxymethylpyrimidine kinase |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |