Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Geobacillus sp. Y412MC61

Type Regulator Effector Pathway Genes Sites
TF AraR Arabinose Arabinose utilization 3 4
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 3 6
TF AseR Arsenite Arsenic resistance 1 1
TF BirA Biotin Biotin biosynthesis 3 3
TF BkdR Branched-chain amino acid degradation 1 1
TF CcpA HPr, phosphocarrier protein Carbon catabolism 22 24
TF CcpN Gluconeogenesis 2 2
TF CggR Fructose-1,6-diphosphate Glycolysis 1 2
TF CodY Guanosine triphosphate; Branched-chain amino acids Amino acid metabolism 38 61
TF CtsR Heat shock Heat shock response 3 4
TF CymR O-acetyl-L-serine; CysK, cysteine synthetase Cysteine metabolism 5 5
TF CysL Sulfate; Sulfite; Thiosulfate Sulfite reduction 2 10
TF CzrA Zinc ion, (Zn2+); Silver ion, (Ag+); Nickel ion, (Ni2+); Copper ion, (Cu2+); Cobalt ion, (Co2+); Cadmium, ion (Cd2+) Zinc resistance; Nickel resistance; Copper resistance; Cobalt resistance; Cadmium resistance 1 1
TF FadR Palmitoyl-CoA; Oleoyl-CoA Fatty acid degradation 6 8
TF FapR Malonyl-CoA Fatty acid biosynthesis 1 1
TF Fnr Oxygen Anaerobic metabolism 2 2
TF Fur Iron ion, (Fe2+) Iron homeostasis 2 8
TF GlnR Feedback-inhibited GlnA, glutamine synthetase Nitrogen assimilation 2 3
TF GltC Glutamate; 2-oxoglutarate; RocG, glutamate dehydrogenase Glutamate metabolism 2 2
TF GmuR Glucomannan utilization 1 1
TF HisR Histidine Histidine biosynthesis 1 1
TF HrcA Heat shock Heat shock response 2 2
TF KipR Sporulation 2 2
TF LexA DNA damage SOS response 9 14
TF LiaR LiaS, sensor histidine kinase (bacitracin, nisin, ramoplanin, vancomycin) Cell wall-active antibiotics stress response 1 1
TF LutR L-lactate Lactate utilization 3 3
TF MhqR 2-Methylhydroquinone and catechol resistance 2 2
TF MtlR MtlA, mannitol-specific enzyme IICB PTS component; HPr, phosphocarrier protein Mannitol utilization 1 1
TF NagR N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 1 1
TF NiaR Niacin NAD biosynthesis 3 3
TF NsrR Nitric oxide Nitrosative stress response 2 4
TF PerR Hydrogen peroxide; Manganese ion, (Mn2+); Iron ion, (Fe2+) Oxidative stress response; Peroxide stress response 7 12
TF PurR 5-phosphoribosyl 1-pyrophosphate Purine metabolism 6 6
TF RbsR Ribose Ribose utilization 1 1
TF Rex NADH Energy metabolism 2 2
TF RocR Ornithine; L-citrulline Arginine degradation; Ornithine degradation 3 5
TF SdpR SdpI, signal transduction protein Toxin-antitoxin system 1 1
TF TnrA NrgB, ammonium uptake protein; NrgA, ammonium uptake protein; Feedback-inhibited GlnA, glutamine synthetase Nitrogen assimilation 20 29
TF TreR Trehalose-6-phosphate Trehalose utilization 1 2
TF UxuR Aldotetraouronic acid Glucuronate utilization 2 2
TF XylR Xylose Xylose utilization 4 4
TF YhgD 2 2
TF YisR Metabolite transport 1 1
TF YrkD Multidrug resistance 6 7
TF YtlI L-cystine transporter 1 3
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 2 2
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