Regulons of Corynebacterium diphtheriae NCTC 13129
|
Allows to visualize regulome content in the context of metabolic pathways |
|
Type |
Regulator |
Effector |
Pathway |
Operons |
Sites |
TF |
AcnR |
Citrate |
Tricarboxylic acid cycle |
1 |
1 |
TF |
AmtR |
GlnK-AMP, signal transduction protein |
Nitrogen metabolism |
4 |
3 |
TF |
ArgR |
Arginine |
Arginine biosynthesis |
2 |
2 |
TF |
BioQ |
Biotin |
Biotin biosynthesis |
6 |
6 |
TF |
BioQ |
Biotin |
Biotin biosynthesis |
5 |
5 |
TF |
Cg0454 |
|
Multidrug resistance |
1 |
2 |
TF |
Cg3261 |
|
Multidrug resistance; Multidrug efflux |
1 |
1 |
TF |
ClgR |
DNA damage |
Proteolysis |
8 |
6 |
TF |
DtxR |
Iron ion, (Fe2+) |
Iron homeostasis |
30 |
29 |
TF |
FasR |
|
Fatty acid biosynthesis |
3 |
2 |
TF |
GlxR |
Cyclic 3',5'-AMP |
Energy metabolism; Carbohydrate metabolism |
78 |
51 |
TF |
HrcA |
Heat shock |
Heat shock response |
2 |
3 |
TF |
HspR |
Heat shock |
Heat shock response |
3 |
3 |
TF |
LexA |
DNA damage |
SOS response |
15 |
9 |
TF |
LldR |
L-lactate |
Lactate utilization |
5 |
4 |
TF |
LtbR |
|
Tryptophan biosynthesis; Leucine biosynthesis |
6 |
7 |
TF |
LysG |
Lysine; Histidine; Arginine |
Amino acid efflux |
2 |
2 |
TF |
McbR |
S-adenosylmethionine; S-adenosylhomocysteine |
Methionine biosynthesis |
15 |
12 |
TF |
MntR |
Manganese ion, (Mn2+) |
Manganese homeostasis |
3 |
2 |
TF |
NanR |
N-acetylneuraminic acid |
Sialic acid utilization |
4 |
6 |
TF |
NrdR |
Deoxyribonucleotides |
Deoxyribonucleotide biosynthesis |
2 |
5 |
TF |
NrtR |
Adenosine diphosphate ribose |
NAD biosynthesis |
2 |
1 |
TF |
PdxR |
Pyridoxal-5-phosphate |
Pyridoxine biosynthesis |
1 |
1 |
TF |
QacR |
|
Drug resistance |
1 |
1 |
TF |
RbsR |
Ribose |
Ribose utilization |
1 |
1 |
TF |
RosR |
Hydrogen peroxide; Manganese ion, (Mn2+); Iron ion, (Fe2+) |
Peroxide stress response |
8 |
4 |
TF |
SufR |
Iron-sulfur cluster redox state |
Iron-sulfur cluster biogenesis |
1 |
1 |
TF |
Znr |
Zinc ion, (Zn2+) |
Zinc homeostasis |
1 |
1 |
TF |
Zur |
Zinc ion, (Zn2+) |
Zinc homeostasis |
7 |
7 |
RNA |
Cobalamin |
Adenosylcobalamin |
Cobalamin biosynthesis |
1 |
1 |
RNA |
L10_leader |
|
Ribosome biogenesis |
1 |
1 |
RNA |
PyrR |
PyrR |
Pyrimidine metabolism |
1 |
1 |
RNA |
S15 |
|
Ribosome biogenesis |
1 |
1 |
RNA |
T-box(Ile) |
Ile-tRNA |
Amino acid metabolism |
1 |
1 |
RNA |
TPP |
Thiamine pyrophosphate |
Thiamine biosynthesis |
3 |
3 |
RNA |
Trp_leader |
|
Tryptophan biosynthesis |
3 |
2 |
RNA |
yybP-ykoY |
|
|
1 |
1 |
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