Regulon of McbR in Corynebacterium diphtheriae NCTC 13129

Properties
Regulator type:	Transcription factor
TF locus tag:	DIP2274
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Methionine biosynthesis
Effector:	S-adenosylmethionine; S-adenosylhomocysteine
Regulog:	McbR - Corynebacteriaceae
Statistics of regulated genes:
- Genes	13
- Operons	9
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 162 sites [see more]

Member of regulog collections

By taxonomy - Corynebacteriaceae
By TF family - TetR
By effector - S-adenosylmethionine
By effector - S-adenosylhomocysteine
By pathway - Methionine biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -17 Score: 4.5 Sequence: CATACTAAGCTGTCTA Locus tag: DIP1259 Name: metH Funciton: 5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13)
	DIP1259	metH	5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13)
Position: -126 Score: 4.6 Sequence: CGTACCGATCGGTCTA Position: -37 Score: 4.4 Sequence: TAGACAAGCTGGTCTA Locus tag: DIP0123 Name: cysR Funciton: Sulphur metabolism transcriptional regulator CysR, ROK family
	DIP0123	cysR	Sulphur metabolism transcriptional regulator CysR, ROK family
Position: -152 Score: 4.5 Sequence: TAGACCGATCGGTACG Position: -130 Score: 4.6 Sequence: AAGACAATTCTGTCTA Locus tag: DIP1890 Name: cysK Funciton: Cysteine synthase (EC 2.5.1.47) Locus tag: DIP1891 Name: cysE Funciton: Serine acetyltransferase (EC 2.3.1.30)
	DIP1890	cysK	Cysteine synthase (EC 2.5.1.47)
	DIP1891	cysE	Serine acetyltransferase (EC 2.3.1.30)
Position: -60 Score: 5.2 Sequence: TAGACAGAGCTGTCCA Locus tag: DIP0623 Name: metX Funciton: Homoserine O-acetyltransferase (EC 2.3.1.31)
	DIP0623	metX	Homoserine O-acetyltransferase (EC 2.3.1.31)
Position: -138 Score: 4.1 Sequence: CGCACCACTTTGTCTA Position: -82 Score: 4.6 Sequence: TAGACCGATCGGTTTC Locus tag: DIP0630 Name: metY Funciton: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
	DIP0630	metY	O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Position: -76 Score: 4.7 Sequence: TAGACCGAGCTGTACA Locus tag: DIP0610 Name: metQ Funciton: Methionine ABC transporter substrate-binding protein Locus tag: DIP0609 Name: metN Funciton: Methionine ABC transporter ATP-binding protein Locus tag: DIP0608 Name: metI Funciton: Methionine ABC transporter permease protein
	DIP0610	metQ	Methionine ABC transporter substrate-binding protein
	DIP0609	metN	Methionine ABC transporter ATP-binding protein
	DIP0608	metI	Methionine ABC transporter permease protein
Position: -74 Score: 4.7 Sequence: TAGACTGATCTGTTCA Locus tag: DIP2274 Name: mcbR Funciton: Methionine biosynthesis transcriptional regulator McbR, TetR family
	DIP2274	mcbR	Methionine biosynthesis transcriptional regulator McbR, TetR family
Position: -166 Score: 4.7 Sequence: TAGACAAAGCTGTACA Locus tag: DIP0611 Name: metQ Funciton: Methionine ABC transporter substrate-binding protein
	DIP0611	metQ	Methionine ABC transporter substrate-binding protein
Position: -116 Score: 5.5 Sequence: TAGACAGCTTGGTCTA Locus tag: DIP1325 Name: metK Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6) Locus tag: DIP1324 Name: priA Funciton: Helicase PriA essential for oriC/DnaA-independent DNA replication
	DIP1325	metK	S-adenosylmethionine synthetase (EC 2.5.1.6)
	DIP1324	priA	Helicase PriA essential for oriC/DnaA-independent DNA replication

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of McbR in Corynebacterium diphtheriae NCTC 13129

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --