Regulog GosR - Bifidobacteriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:
Biological process:	Galactooligosaccharide utilization; Galactan utilization
Effector:	Galactobiose
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 17 sites [see more]

Member of regulog collections

By taxonomy - Bifidobacteriaceae
By TF family - LacI
By effector - Galactobiose
By pathway - Galactooligosaccharide utilization
By pathway - Galactan utilization

Statistics of regulated genes
Genome	Genes	Operons
Bifidobacterium longum subsp. infantis ATCC 15697
Bifidobacterium adolescentis ATCC 15703	6	2
Bifidobacterium angulatum DSM 20098	3	1
Bifidobacterium animalis subsp. lactis AD011
Bifidobacterium bifidum NCIMB 41171	3	1
Bifidobacterium breve DSM 20213	1	1
Bifidobacterium dentium Bd1	5	3
Bifidobacterium gallicum DSM 20093
Bifidobacterium longum NCC2705	2	2
Gardnerella vaginalis 409-05

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes											Function

CRON 1.
gosB2	Bifidobacterium longum subsp. infantis ATCC 15697	* Bifidobacterium adolescentis ATCC 15703 Site: position = -159 score = 5.27321 sequence = CAGGTACACAGTTATACCAA Site: position = -190 score = 4.85253 sequence = ATGGTACACCGGAAAACCTA Gene: BAD_1405: Putative galactooligosaccharide ABC transporter, sugar-binding protein	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Putative galactooligosaccharide ABC transporter, sugar-binding protein
gosC2	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703 Gene: BAD_1404: Putative galactooligosaccharide ABC transporter, permease protein 1	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Putative galactooligosaccharide ABC transporter, permease protein 1
gosD2	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703 Gene: BAD_1403: Putative galactooligosaccharide ABC transporter, permease protein 2	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Putative galactooligosaccharide ABC transporter, permease protein 2
bgaB2	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703 Gene: BAD_1402: Beta-galactosidase (EC 3.2.1.23)	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Beta-galactosidase (EC 3.2.1.23)

CRON 2.
galA	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213	* Bifidobacterium dentium Bd1 Site: position = -29 score = 5.75047 sequence = TTGGTACAACGGTGTCTCTA Gene: BDP_2054: Arabinogalactan endo-beta-1,4-galactanase (EC 3.2.1.89)	Bifidobacterium gallicum DSM 20093	* Bifidobacterium longum NCC2705 Site: position = -97 score = 4.95726 sequence = GTGGTACACAGCTGTACCGC Site: position = -147 score = 5.84454 sequence = TTGATACACCGGTTGACCAA Gene: BL0257: Arabinogalactan endo-beta-1,4-galactanase (EC 3.2.1.89)	Gardnerella vaginalis 409-05	Arabinogalactan endo-beta-1,4-galactanase (EC 3.2.1.89)

CRON 3.
BbifN4_010100001412	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	* Bifidobacterium bifidum NCIMB 41171 Site: position = -39 score = 4.88967 sequence = CTGGTATAGCGGTGCATCAT Site: position = -11 score = 6.09143 sequence = TTGATACTCCGTTGTATCAA Gene: BbifN4_010100001412: hypothetical protein	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	hypothetical protein
BbifN4_010100001417	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171 Gene: BbifN4_010100001417: hypothetical protein	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	hypothetical protein
PF00248	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0442: Aldo/keto reductase	Bifidobacterium adolescentis ATCC 15703 Gene: BAD_1396: Aldo/keto reductase	Bifidobacterium angulatum DSM 20098 Gene: BIFANG_00154: Aldo/keto reductase	Bifidobacterium animalis subsp. lactis AD011 Gene: BLA_0059: Aldo/keto reductase	Bifidobacterium bifidum NCIMB 41171 Gene: BbifN4_010100001422: Aldo/keto reductase	Bifidobacterium breve DSM 20213 Gene: BIFBRE_02227: Aldo/keto reductase	Bifidobacterium dentium Bd1 Gene: BDP_1903: Aldo/keto reductase	Bifidobacterium gallicum DSM 20093 Gene: BIFGAL_00641: Aldo/keto reductase	Bifidobacterium longum NCC2705 Gene: BL0255: Aldo/keto reductase	Gardnerella vaginalis 409-05	Aldo/keto reductase
bgaB	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_2123: Beta-galactosidase (EC 3.2.1.23), GH42 family	* Bifidobacterium adolescentis ATCC 15703 Site: position = -60 score = 6.05088 sequence = ATGCTACACCGGTGTACCAC Gene: BAD_1401: Beta-galactosidase (EC 3.2.1.23), GH42 family	* Bifidobacterium angulatum DSM 20098 Site: position = 17 score = 5.88674 sequence = GTGGTACAACTGTGTATCAT Gene: BIFANG_00156: Beta-galactosidase (EC 3.2.1.23), GH42 family	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171 Gene: BbifN4_010100000420: Beta-galactosidase (EC 3.2.1.23), GH42 family	Bifidobacterium breve DSM 20213 Gene: BIFBRE_02225: Beta-galactosidase (EC 3.2.1.23), GH42 family	* Bifidobacterium dentium Bd1 Site: position = -72 score = 6.1572 sequence = TTGCTACACCGTTGTATCAT Gene: BDP_1908: Beta-galactosidase (EC 3.2.1.23), GH42 family	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705 Gene: BL0259: Beta-galactosidase (EC 3.2.1.23), GH42 family	Gardnerella vaginalis 409-05	Beta-galactosidase (EC 3.2.1.23), GH42 family
gosR	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0439: Predicted transcriptional regulator of galactan utilization, LacI family	Bifidobacterium adolescentis ATCC 15703 Gene: BAD_1400: Predicted transcriptional regulator of galactan utilization, LacI family	Bifidobacterium angulatum DSM 20098 Gene: BIFANG_00155: Predicted transcriptional regulator of galactan utilization, LacI family	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171 Gene: BbifN4_010100001407: Predicted transcriptional regulator of galactan utilization, LacI family	Bifidobacterium breve DSM 20213 Gene: BIFBRE_02226: Predicted transcriptional regulator of galactan utilization, LacI family	Bifidobacterium dentium Bd1 Gene: BDP_1907: Predicted transcriptional regulator of galactan utilization, LacI family	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705 Gene: BL0258: Predicted transcriptional regulator of galactan utilization, LacI family	Gardnerella vaginalis 409-05	Predicted transcriptional regulator of galactan utilization, LacI family

CRON 4.
gosB	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	* Bifidobacterium breve DSM 20213 Site: position = -260 score = 6.32638 sequence = TTGGTACACAGGTGTATCAT Site: position = -232 score = 5.58617 sequence = TTGGTACATGGGTGTACCAA Gene: BIFBRE_02223: Putative galactooligosaccharide ABC transporter, substrate-binding component	* Bifidobacterium dentium Bd1 Site: position = -216 score = 5.94546 sequence = TTGATACAGCTGTGTATCAT Site: position = -188 score = 5.8045 sequence = ATGATACACAGTTGTATCAG Site: position = -98 score = 5.97821 sequence = TTGGTACAGCGGTATATCAA Gene: BDP_1911: Putative galactooligosaccharide ABC transporter, substrate-binding component	Bifidobacterium gallicum DSM 20093	* Bifidobacterium longum NCC2705 Site: position = -253 score = 6.12709 sequence = TTGGTACACGGGTGTACCAA Site: position = -281 score = 6.32638 sequence = TTGGTACACAGGTGTATCAT Gene: BL0262: Putative galactooligosaccharide ABC transporter, substrate-binding component	Gardnerella vaginalis 409-05	Putative galactooligosaccharide ABC transporter, substrate-binding component
gosC	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1 Gene: BDP_1910: Putative galactooligosaccharide ABC transporter, permease component 1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705 Gene: BL0261: Putative galactooligosaccharide ABC transporter, permease component 1	Gardnerella vaginalis 409-05	Putative galactooligosaccharide ABC transporter, permease component 1
gosD	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1 Gene: BDP_1909: Putative galactooligosaccharide ABC transporter, permease component 2	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705 Gene: BL0260: Putative galactooligosaccharide ABC transporter, permease component 2	Gardnerella vaginalis 409-05	Putative galactooligosaccharide ABC transporter, permease component 2

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog GosR - Bifidobacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --