Statistics of regulated genes

Genome	Genes	Operons
Mycobacterium abscessus ATCC 19977	12	8
Mycobacterium avium 104	13	9
Mycobacterium flavescens PYR-GCK	10	8
Mycobacterium leprae TN	4	3
Mycobacterium marinum M	13	9
Mycobacterium smegmatis str. MC2 155	12	8
Mycobacterium sp. JLS	11	7
Mycobacterium tuberculosis H37Rv	15	11
Mycobacterium vanbaalenii PYR-1	11	7

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes										Function
CRON 1.
lexA	* Mycobacterium abscessus ATCC 19977 Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Site: position = -169 score = 5.48704 sequence = TCGATCATGTGTTCGA Site: position = -150 score = 5.07538 sequence = CCGAACATGTGATCGA Gene: MAB_3038: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Mycobacterium avium 104 Site: position = -287 score = 4.96858 sequence = TCGCTCGTGTGTTCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: MAV_3614: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Mycobacterium flavescens PYR-GCK Site: position = -128 score = 5.40398 sequence = TCGATCAGGTGTTCGA Site: position = -108 score = 5.07538 sequence = TAGAACATGTGATCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: Mflv_3956: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Mycobacterium leprae TN Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Site: position = -232 score = 5.5281 sequence = TCGATCATATGTTCGA Gene: ML1003: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Mycobacterium marinum M Site: position = -282 score = 5.08124 sequence = TCGCTCAAGTGTTCGA Site: position = -258 score = 5.16341 sequence = TCGCTCACGTGTTCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: MMAR_1992: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Mycobacterium smegmatis str. MC2 155 Site: position = -217 score = 5.20447 sequence = TCGCTCACATGTTCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: MSMEG_2740: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Mycobacterium sp. JLS Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Site: position = -139 score = 5.40398 sequence = TCGATCAGGTGTTCGA Gene: Mjls_2157: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Mycobacterium tuberculosis H37Rv Site: position = -238 score = 4.9932 sequence = CCGAACATTTGATCGA Site: position = -105 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: Rv2720: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Mycobacterium vanbaalenii PYR-1 Site: position = -163 score = 5.03431 sequence = TAGAACACGTGATCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Site: position = -183 score = 5.40398 sequence = TCGATCAGGTGTTCGA Gene: Mvan_2441: SOS-response repressor and protease LexA (EC 3.4.21.88)	SOS-response repressor and protease LexA (EC 3.4.21.88)
CRON 2.
recA	* Mycobacterium abscessus ATCC 19977 Site: position = -143 score = 5.23421 sequence = TCGAACAGATGTTCGC Gene: MAB_3060c: Recombinase A	* Mycobacterium avium 104 Site: position = -123 score = 5.44306 sequence = TCGAACACCTGTTCGG Gene: MAV_3627: Recombinase A	* Mycobacterium flavescens PYR-GCK Site: position = -133 score = 5.19315 sequence = TCGAACACCTGTTCGT Gene: Mflv_3975: Recombinase A	* Mycobacterium leprae TN Site: position = -113 score = 5.48412 sequence = TCGAACAGATGTTCGG Gene: ML0987: Recombinase A	* Mycobacterium marinum M Site: position = -121 score = 5.48412 sequence = TCGAACAGATGTTCGG Gene: MMAR_1977: Recombinase A	* Mycobacterium smegmatis str. MC2 155 Site: position = -121 score = 5.19315 sequence = TCGAACAGGTGTTCGT Gene: MSMEG_2723: Recombinase A	* Mycobacterium sp. JLS Site: position = -138 score = 5.19315 sequence = TCGAACAGGTGTTCGT Gene: Mjls_2134: Recombinase A	* Mycobacterium tuberculosis H37Rv Site: position = -123 score = 5.44306 sequence = TCGAACAGGTGTTCGG Gene: Rv2737c: Recombinase A	* Mycobacterium vanbaalenii PYR-1 Site: position = -121 score = 5.19315 sequence = TCGAACACCTGTTCGT Gene: Mvan_2420: Recombinase A	Recombinase A
recX	Mycobacterium abscessus ATCC 19977 Gene: MAB_3059c: Regulatory protein RecX	Mycobacterium avium 104 Gene: MAV_3626: Regulatory protein RecX	Mycobacterium flavescens PYR-GCK Gene: Mflv_3974: Regulatory protein RecX	Mycobacterium leprae TN Gene: ML0988: Regulatory protein RecX	Mycobacterium marinum M Gene: MMAR_1978: Regulatory protein RecX	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_2724: Regulatory protein RecX	Mycobacterium sp. JLS Gene: Mjls_2135: Regulatory protein RecX	Mycobacterium tuberculosis H37Rv Gene: Rv2736c: Regulatory protein RecX	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_2421: Regulatory protein RecX	Regulatory protein RecX
CRON 3.
alkB	* Mycobacterium abscessus ATCC 19977 Site: position = -28 score = 5.46039 sequence = TCGAACGTATGTGCGA Gene: MAB_1120c: DNA repair system specific for alkylated DNA	* Mycobacterium avium 104 Site: position = -29 score = 5.37733 sequence = TCGAACGGATGTGCGA Gene: MAV_1124: DNA repair system specific for alkylated DNA	* Mycobacterium flavescens PYR-GCK Site: position = -29 score = 5.33626 sequence = TCGAACGCCTGTGCGA Gene: Mflv_1921: DNA repair system specific for alkylated DNA	* Mycobacterium leprae TN Site: position = -8 score = 5.19659 sequence = TCGAACTGATGTGCGA Gene: ML0190: DNA repair system specific for alkylated DNA	* Mycobacterium marinum M Site: position = -8 score = 5.19659 sequence = TCGAACTGATGTGCGA Gene: MMAR_4493: DNA repair system specific for alkylated DNA	* Mycobacterium smegmatis str. MC2 155 Site: position = -29 score = 5.41932 sequence = TCGAACGTGTGTGCGA Gene: MSMEG_5451: DNA repair system specific for alkylated DNA	* Mycobacterium sp. JLS Site: position = -29 score = 5.37826 sequence = TCGAACGCGTGTGCGA Gene: Mjls_4657: DNA repair system specific for alkylated DNA	* Mycobacterium tuberculosis H37Rv Site: position = -8 score = 5.33715 sequence = TCGAACGAATGTGCGA Gene: Rv1000c: DNA repair system specific for alkylated DNA	* Mycobacterium vanbaalenii PYR-1 Site: position = -29 score = 5.33626 sequence = TCGAACGCCTGTGCGA Gene: Mvan_4812: DNA repair system specific for alkylated DNA	DNA repair system specific for alkylated DNA
CRON 4.
dnaE2	* Mycobacterium abscessus ATCC 19977 Site: position = -73 score = 5.85561 sequence = TCGAACAAATGTTCGA Gene: MAB_3703c: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Mycobacterium avium 104 Site: position = -29 score = 5.47916 sequence = TCGAACATCAGTTCGA Gene: MAV_4335: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Mycobacterium flavescens PYR-GCK Site: position = -64 score = 5.6599 sequence = TCGAACGGATGTTCGA Gene: Mflv_4893: DNA polymerase III alpha subunit (EC 2.7.7.7)	Mycobacterium leprae TN	* Mycobacterium marinum M Site: position = -28 score = 5.41259 sequence = TCGAACATATTTTCGA Gene: MMAR_1158: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Mycobacterium smegmatis str. MC2 155 Site: position = -28 score = 5.89672 sequence = TCGAACACGTGTTCGA Gene: MSMEG_1633: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Mycobacterium sp. JLS Site: position = -28 score = 5.66083 sequence = TCGAACGCGTGTTCGA Gene: Mjls_1210: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Mycobacterium tuberculosis H37Rv Site: position = -29 score = 5.73238 sequence = TCGAACAATTGTTCGA Gene: Rv3370c: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Mycobacterium vanbaalenii PYR-1 Site: position = -28 score = 5.57866 sequence = TCGAACGCTTGTTCGA Gene: Mvan_1530: DNA polymerase III alpha subunit (EC 2.7.7.7)	DNA polymerase III alpha subunit (EC 2.7.7.7)
CRON 5.
Rv3395c	* Mycobacterium abscessus ATCC 19977 Site: position = -41 score = 5.56718 sequence = TCGAACATATGTTCTA Gene: MAB_3713c: Recombinase-like hypothetical protein	* Mycobacterium avium 104 Site: position = -52 score = 5.70189 sequence = TCGAACATGCGTTCGA Gene: MAV_4346: Recombinase-like hypothetical protein	* Mycobacterium flavescens PYR-GCK Site: position = -70 score = 4.87273 sequence = TCGAACAAAATTTCGA Gene: Mflv_4899: Recombinase-like hypothetical protein	Mycobacterium leprae TN	* Mycobacterium marinum M Site: position = -51 score = 5.1767 sequence = TCGAACATACTTTCGA Gene: MMAR_1150: Recombinase-like hypothetical protein	* Mycobacterium smegmatis str. MC2 155 Site: position = -52 score = 5.07302 sequence = TCGAACATACATTCGA Gene: MSMEG_1620: Recombinase-like hypothetical protein	* Mycobacterium sp. JLS Site: position = -52 score = 5.52116 sequence = TCGAACATGAGTTCGA Gene: Mjls_1201: Recombinase-like hypothetical protein	* Mycobacterium tuberculosis H37Rv Site: position = -30 score = 5.41259 sequence = TCGAACATATTTTCGA Gene: Rv3395c: Recombinase-like hypothetical protein	* Mycobacterium vanbaalenii PYR-1 Site: position = -52 score = 4.65906 sequence = TCGAACAAAGTTTCGA Gene: Mvan_1522: Recombinase-like hypothetical protein	Recombinase-like hypothetical protein
COG0389	Mycobacterium abscessus ATCC 19977 Gene: MAB_3712c: DNA polymerase-like protein PA0670	Mycobacterium avium 104 Gene: MAV_4344: DNA polymerase-like protein PA0670	Mycobacterium flavescens PYR-GCK Gene: Mflv_4898: DNA polymerase-like protein PA0670	Mycobacterium leprae TN	Mycobacterium marinum M Gene: MMAR_1151: DNA polymerase-like protein PA0670	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_1622: DNA polymerase-like protein PA0670	Mycobacterium sp. JLS Gene: Mjls_1202: DNA polymerase-like protein PA0670	Mycobacterium tuberculosis H37Rv Gene: Rv3394c: DNA polymerase-like protein PA0670	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_1523: DNA polymerase-like protein PA0670	DNA polymerase-like protein PA0670
CRON 6.
ruvC	* Mycobacterium abscessus ATCC 19977 Site: position = -82 score = 5.36089 sequence = TCGAACAACTGTTCTA Gene: MAB_2884c: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	* Mycobacterium avium 104 Site: position = -33 score = 5.40106 sequence = TCGAACAGCTGTTCTA Gene: MAV_3475: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	Mycobacterium flavescens PYR-GCK Gene: Mflv_3826: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	Mycobacterium leprae TN Gene: ML0481: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	* Mycobacterium marinum M Site: position = -46 score = 5.32071 sequence = TCGAACAATTGTTCGG Gene: MMAR_2109: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	* Mycobacterium smegmatis str. MC2 155 Site: position = -30 score = 5.07246 sequence = TCGAACAGATGTTCTG Gene: MSMEG_2943: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	* Mycobacterium sp. JLS Site: position = -8 score = 4.78148 sequence = TCGAACAGGTGTTCTC Gene: Mjls_2304: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	* Mycobacterium tuberculosis H37Rv Site: position = -37 score = 5.08482 sequence = TCGAACGATTGTTCGG Gene: Rv2594c: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	* Mycobacterium vanbaalenii PYR-1 Site: position = -34 score = 5.07246 sequence = TCGAACAGATGTTCTG Gene: Mvan_2573: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)	Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
ruvA	Mycobacterium abscessus ATCC 19977 Gene: MAB_2883c: Holliday junction DNA helicase RuvA	Mycobacterium avium 104 Gene: MAV_3474: Holliday junction DNA helicase RuvA	Mycobacterium flavescens PYR-GCK Gene: Mflv_3825: Holliday junction DNA helicase RuvA	Mycobacterium leprae TN Gene: ML0482: Holliday junction DNA helicase RuvA	Mycobacterium marinum M Gene: MMAR_2110: Holliday junction DNA helicase RuvA	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_2944: Holliday junction DNA helicase RuvA	Mycobacterium sp. JLS Gene: Mjls_2305: Holliday junction DNA helicase RuvA	Mycobacterium tuberculosis H37Rv Gene: Rv2593c: Holliday junction DNA helicase RuvA	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_2574: Holliday junction DNA helicase RuvA	Holliday junction DNA helicase RuvA
ruvB	Mycobacterium abscessus ATCC 19977 Gene: MAB_2882c: Holliday junction DNA helicase RuvB	Mycobacterium avium 104 Gene: MAV_3473: Holliday junction DNA helicase RuvB	Mycobacterium flavescens PYR-GCK Gene: Mflv_3824: Holliday junction DNA helicase RuvB	Mycobacterium leprae TN Gene: ML0483: Holliday junction DNA helicase RuvB	Mycobacterium marinum M Gene: MMAR_2111: Holliday junction DNA helicase RuvB	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_2945: Holliday junction DNA helicase RuvB	Mycobacterium sp. JLS Gene: Mjls_2306: Holliday junction DNA helicase RuvB	Mycobacterium tuberculosis H37Rv Gene: Rv2592c: Holliday junction DNA helicase RuvB	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_2575: Holliday junction DNA helicase RuvB	Holliday junction DNA helicase RuvB
CRON 7.
Rv3074	Mycobacterium abscessus ATCC 19977	* Mycobacterium avium 104 Site: position = -23 score = 5.89672 sequence = TCGAACACGTGTTCGA Gene: MAV_3980: Conserved hypothetical protein	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	* Mycobacterium marinum M Site: position = -8 score = 5.93778 sequence = TCGAACACATGTTCGA Gene: MMAR_1584: Conserved hypothetical protein	Mycobacterium smegmatis str. MC2 155	Mycobacterium sp. JLS	* Mycobacterium tuberculosis H37Rv Site: position = -8 score = 5.93778 sequence = TCGAACACATGTTCGA Gene: Rv3074: Conserved hypothetical protein	Mycobacterium vanbaalenii PYR-1	Conserved hypothetical protein
CRON 8.
PF02720	* Mycobacterium abscessus ATCC 19977 Site: position = -8 score = 5.32294 sequence = TCAAACGCATGTTCGA Gene: MAB_4752: HNH endonuclease	Mycobacterium avium 104	*2 Mycobacterium flavescens PYR-GCK Site: position = 1 score = 5.27621 sequence = TGGAACACATGTTCGA Gene: Mflv_3422: HNH endonuclease Site: position = -8 score = 5.93778 sequence = TCGAACACATGTTCGA Gene: Mflv_4927: HNH endonuclease	Mycobacterium leprae TN	Mycobacterium marinum M	*2 Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_5583: HNH endonuclease Site: position = -8 score = 5.46039 sequence = TCGAACGTATGTGCGA Gene: MSMEG_3957: HNH endonuclease	Mycobacterium sp. JLS	*2 Mycobacterium tuberculosis H37Rv Site: position = -8 score = 5.74296 sequence = TCGAACGTATGTTCGA Gene: Rv3776: HNH endonuclease Gene: Rv2100: HNH endonuclease	Mycobacterium vanbaalenii PYR-1	HNH endonuclease
CRON 9.
Rv0336	Mycobacterium abscessus ATCC 19977	* Mycobacterium avium 104 Site: position = -8 score = 5.69628 sequence = TCGAACATATGTGCGA Gene: MAV_4456: Conserved hypothetical protein	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	* Mycobacterium marinum M Site: position = -8 score = 5.07302 sequence = TCGAATGTATGTTCGA Gene: MMAR_5187: Conserved hypothetical protein	Mycobacterium smegmatis str. MC2 155	Mycobacterium sp. JLS	*2 Mycobacterium tuberculosis H37Rv Site: position = -32 score = 5.1767 sequence = TCGAAAGTATGTTCGA Gene: Rv0515: Conserved hypothetical protein Site: position = -32 score = 5.1767 sequence = TCGAAAGTATGTTCGA Gene: Rv0336: Conserved hypothetical protein	Mycobacterium vanbaalenii PYR-1	Conserved hypothetical protein
CRON 10.
splB	* Mycobacterium abscessus ATCC 19977 Site: position = -24 score = 5.31727 sequence = TCGAACATATGTTCGC Gene: MAB_2868c: DNA repair photolyase	* Mycobacterium avium 104 Site: position = -25 score = 5.4381 sequence = TCGAACTGGTGTTCGA Gene: MAV_3456: DNA repair photolyase	* Mycobacterium flavescens PYR-GCK Site: position = -23 score = 5.08138 sequence = TCGAACGTATGTTCGC Gene: Mflv_3795: DNA repair photolyase	Mycobacterium leprae TN	* Mycobacterium marinum M Site: position = -25 score = 5.39792 sequence = TCGAACTAGTGTTCGA Gene: MMAR_2148: DNA repair photolyase	* Mycobacterium smegmatis str. MC2 155 Site: position = -8 score = 5.70189 sequence = TCGAACGCATGTTCGA Gene: MSMEG_2990: DNA repair photolyase	* Mycobacterium sp. JLS Site: position = 35 score = 5.11267 sequence = TCGAACCTACGTTCGA Gene: Mjls_2335: DNA repair photolyase	* Mycobacterium tuberculosis H37Rv Site: position = -24 score = 5.125 sequence = TAGAACGGTTGTTCGA Gene: Rv2578c: DNA repair photolyase	* Mycobacterium vanbaalenii PYR-1 Site: position = -23 score = 5.08138 sequence = TCGAACGTATGTTCGC Gene: Mvan_2599: DNA repair photolyase	DNA repair photolyase

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