Regulog LexA - Mycobacteriaceae
| Regulator type: | Transcription factor |
| Regulator family: | LexA |
| Regulation mode: | repressor |
| Biological process: | SOS response |
| Effector: | DNA damage |
| Phylum: | Actinobacteria |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By trascription factor - LexA
- By taxonomy - Mycobacteriaceae
- By TF family - LexA
- By effector - DNA damage
- By pathway - SOS response
| Genome | Genes | Operons |
|---|---|---|
| Mycobacterium abscessus ATCC 19977 | 12 | 8 |
| Mycobacterium avium 104 | 13 | 9 |
| Mycobacterium flavescens PYR-GCK | 10 | 8 |
| Mycobacterium leprae TN | 4 | 3 |
| Mycobacterium marinum M | 13 | 9 |
| Mycobacterium smegmatis str. MC2 155 | 12 | 8 |
| Mycobacterium sp. JLS | 11 | 7 |
| Mycobacterium tuberculosis H37Rv | 15 | 11 |
| Mycobacterium vanbaalenii PYR-1 | 11 | 7 |
| Genes | Function | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||
| lexA |
*
Mycobacterium abscessus ATCC 19977 Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Site: position = -169 score = 5.48704 sequence = TCGATCATGTGTTCGA Site: position = -150 score = 5.07538 sequence = CCGAACATGTGATCGA Gene: MAB_3038: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Mycobacterium avium 104 Site: position = -287 score = 4.96858 sequence = TCGCTCGTGTGTTCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: MAV_3614: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Mycobacterium flavescens PYR-GCK Site: position = -128 score = 5.40398 sequence = TCGATCAGGTGTTCGA Site: position = -108 score = 5.07538 sequence = TAGAACATGTGATCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: Mflv_3956: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Mycobacterium leprae TN Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Site: position = -232 score = 5.5281 sequence = TCGATCATATGTTCGA Gene: ML1003: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Mycobacterium marinum M Site: position = -282 score = 5.08124 sequence = TCGCTCAAGTGTTCGA Site: position = -258 score = 5.16341 sequence = TCGCTCACGTGTTCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: MMAR_1992: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -217 score = 5.20447 sequence = TCGCTCACATGTTCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: MSMEG_2740: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Mycobacterium sp. JLS Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Site: position = -139 score = 5.40398 sequence = TCGATCAGGTGTTCGA Gene: Mjls_2157: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Mycobacterium tuberculosis H37Rv Site: position = -238 score = 4.9932 sequence = CCGAACATTTGATCGA Site: position = -105 score = 5.55883 sequence = TCGAACACATGTTTGA Gene: Rv2720: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Mycobacterium vanbaalenii PYR-1 Site: position = -163 score = 5.03431 sequence = TAGAACACGTGATCGA Site: position = -48 score = 5.55883 sequence = TCGAACACATGTTTGA Site: position = -183 score = 5.40398 sequence = TCGATCAGGTGTTCGA Gene: Mvan_2441: SOS-response repressor and protease LexA (EC 3.4.21.88) |
SOS-response repressor and protease LexA (EC 3.4.21.88) |
| CRON 2. | ||||||||||
| recA |
*
Mycobacterium abscessus ATCC 19977 Site: position = -143 score = 5.23421 sequence = TCGAACAGATGTTCGC Gene: MAB_3060c: Recombinase A |
*
Mycobacterium avium 104 Site: position = -123 score = 5.44306 sequence = TCGAACACCTGTTCGG Gene: MAV_3627: Recombinase A |
*
Mycobacterium flavescens PYR-GCK Site: position = -133 score = 5.19315 sequence = TCGAACACCTGTTCGT Gene: Mflv_3975: Recombinase A |
*
Mycobacterium leprae TN Site: position = -113 score = 5.48412 sequence = TCGAACAGATGTTCGG Gene: ML0987: Recombinase A |
*
Mycobacterium marinum M Site: position = -121 score = 5.48412 sequence = TCGAACAGATGTTCGG Gene: MMAR_1977: Recombinase A |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -121 score = 5.19315 sequence = TCGAACAGGTGTTCGT Gene: MSMEG_2723: Recombinase A |
*
Mycobacterium sp. JLS Site: position = -138 score = 5.19315 sequence = TCGAACAGGTGTTCGT Gene: Mjls_2134: Recombinase A |
*
Mycobacterium tuberculosis H37Rv Site: position = -123 score = 5.44306 sequence = TCGAACAGGTGTTCGG Gene: Rv2737c: Recombinase A |
*
Mycobacterium vanbaalenii PYR-1 Site: position = -121 score = 5.19315 sequence = TCGAACACCTGTTCGT Gene: Mvan_2420: Recombinase A |
Recombinase A |
| recX |
Gene: MAB_3059c: Regulatory protein RecX |
Gene: MAV_3626: Regulatory protein RecX |
Gene: Mflv_3974: Regulatory protein RecX |
Gene: ML0988: Regulatory protein RecX |
Gene: MMAR_1978: Regulatory protein RecX |
Gene: MSMEG_2724: Regulatory protein RecX |
Gene: Mjls_2135: Regulatory protein RecX |
Gene: Rv2736c: Regulatory protein RecX |
Gene: Mvan_2421: Regulatory protein RecX |
Regulatory protein RecX |
| CRON 3. | ||||||||||
| alkB |
*
Mycobacterium abscessus ATCC 19977 Site: position = -28 score = 5.46039 sequence = TCGAACGTATGTGCGA Gene: MAB_1120c: DNA repair system specific for alkylated DNA |
*
Mycobacterium avium 104 Site: position = -29 score = 5.37733 sequence = TCGAACGGATGTGCGA Gene: MAV_1124: DNA repair system specific for alkylated DNA |
*
Mycobacterium flavescens PYR-GCK Site: position = -29 score = 5.33626 sequence = TCGAACGCCTGTGCGA Gene: Mflv_1921: DNA repair system specific for alkylated DNA |
*
Mycobacterium leprae TN Site: position = -8 score = 5.19659 sequence = TCGAACTGATGTGCGA Gene: ML0190: DNA repair system specific for alkylated DNA |
*
Mycobacterium marinum M Site: position = -8 score = 5.19659 sequence = TCGAACTGATGTGCGA Gene: MMAR_4493: DNA repair system specific for alkylated DNA |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -29 score = 5.41932 sequence = TCGAACGTGTGTGCGA Gene: MSMEG_5451: DNA repair system specific for alkylated DNA |
*
Mycobacterium sp. JLS Site: position = -29 score = 5.37826 sequence = TCGAACGCGTGTGCGA Gene: Mjls_4657: DNA repair system specific for alkylated DNA |
*
Mycobacterium tuberculosis H37Rv Site: position = -8 score = 5.33715 sequence = TCGAACGAATGTGCGA Gene: Rv1000c: DNA repair system specific for alkylated DNA |
*
Mycobacterium vanbaalenii PYR-1 Site: position = -29 score = 5.33626 sequence = TCGAACGCCTGTGCGA Gene: Mvan_4812: DNA repair system specific for alkylated DNA |
DNA repair system specific for alkylated DNA |
| CRON 4. | ||||||||||
| dnaE2 |
*
Mycobacterium abscessus ATCC 19977 Site: position = -73 score = 5.85561 sequence = TCGAACAAATGTTCGA Gene: MAB_3703c: DNA polymerase III alpha subunit (EC 2.7.7.7) |
*
Mycobacterium avium 104 Site: position = -29 score = 5.47916 sequence = TCGAACATCAGTTCGA Gene: MAV_4335: DNA polymerase III alpha subunit (EC 2.7.7.7) |
*
Mycobacterium flavescens PYR-GCK Site: position = -64 score = 5.6599 sequence = TCGAACGGATGTTCGA Gene: Mflv_4893: DNA polymerase III alpha subunit (EC 2.7.7.7) |
|
*
Mycobacterium marinum M Site: position = -28 score = 5.41259 sequence = TCGAACATATTTTCGA Gene: MMAR_1158: DNA polymerase III alpha subunit (EC 2.7.7.7) |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -28 score = 5.89672 sequence = TCGAACACGTGTTCGA Gene: MSMEG_1633: DNA polymerase III alpha subunit (EC 2.7.7.7) |
*
Mycobacterium sp. JLS Site: position = -28 score = 5.66083 sequence = TCGAACGCGTGTTCGA Gene: Mjls_1210: DNA polymerase III alpha subunit (EC 2.7.7.7) |
*
Mycobacterium tuberculosis H37Rv Site: position = -29 score = 5.73238 sequence = TCGAACAATTGTTCGA Gene: Rv3370c: DNA polymerase III alpha subunit (EC 2.7.7.7) |
*
Mycobacterium vanbaalenii PYR-1 Site: position = -28 score = 5.57866 sequence = TCGAACGCTTGTTCGA Gene: Mvan_1530: DNA polymerase III alpha subunit (EC 2.7.7.7) |
DNA polymerase III alpha subunit (EC 2.7.7.7) |
| CRON 5. | ||||||||||
| Rv3395c |
*
Mycobacterium abscessus ATCC 19977 Site: position = -41 score = 5.56718 sequence = TCGAACATATGTTCTA Gene: MAB_3713c: Recombinase-like hypothetical protein |
*
Mycobacterium avium 104 Site: position = -52 score = 5.70189 sequence = TCGAACATGCGTTCGA Gene: MAV_4346: Recombinase-like hypothetical protein |
*
Mycobacterium flavescens PYR-GCK Site: position = -70 score = 4.87273 sequence = TCGAACAAAATTTCGA Gene: Mflv_4899: Recombinase-like hypothetical protein |
|
*
Mycobacterium marinum M Site: position = -51 score = 5.1767 sequence = TCGAACATACTTTCGA Gene: MMAR_1150: Recombinase-like hypothetical protein |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -52 score = 5.07302 sequence = TCGAACATACATTCGA Gene: MSMEG_1620: Recombinase-like hypothetical protein |
*
Mycobacterium sp. JLS Site: position = -52 score = 5.52116 sequence = TCGAACATGAGTTCGA Gene: Mjls_1201: Recombinase-like hypothetical protein |
*
Mycobacterium tuberculosis H37Rv Site: position = -30 score = 5.41259 sequence = TCGAACATATTTTCGA Gene: Rv3395c: Recombinase-like hypothetical protein |
*
Mycobacterium vanbaalenii PYR-1 Site: position = -52 score = 4.65906 sequence = TCGAACAAAGTTTCGA Gene: Mvan_1522: Recombinase-like hypothetical protein |
Recombinase-like hypothetical protein |
| COG0389 |
Gene: MAB_3712c: DNA polymerase-like protein PA0670 |
Gene: MAV_4344: DNA polymerase-like protein PA0670 |
Gene: Mflv_4898: DNA polymerase-like protein PA0670 |
|
Gene: MMAR_1151: DNA polymerase-like protein PA0670 |
Gene: MSMEG_1622: DNA polymerase-like protein PA0670 |
Gene: Mjls_1202: DNA polymerase-like protein PA0670 |
Gene: Rv3394c: DNA polymerase-like protein PA0670 |
Gene: Mvan_1523: DNA polymerase-like protein PA0670 |
DNA polymerase-like protein PA0670 |
| CRON 6. | ||||||||||
| ruvC |
*
Mycobacterium abscessus ATCC 19977 Site: position = -82 score = 5.36089 sequence = TCGAACAACTGTTCTA Gene: MAB_2884c: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Mycobacterium avium 104 Site: position = -33 score = 5.40106 sequence = TCGAACAGCTGTTCTA Gene: MAV_3475: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
Gene: Mflv_3826: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
Gene: ML0481: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Mycobacterium marinum M Site: position = -46 score = 5.32071 sequence = TCGAACAATTGTTCGG Gene: MMAR_2109: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -30 score = 5.07246 sequence = TCGAACAGATGTTCTG Gene: MSMEG_2943: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Mycobacterium sp. JLS Site: position = -8 score = 4.78148 sequence = TCGAACAGGTGTTCTC Gene: Mjls_2304: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Mycobacterium tuberculosis H37Rv Site: position = -37 score = 5.08482 sequence = TCGAACGATTGTTCGG Gene: Rv2594c: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Mycobacterium vanbaalenii PYR-1 Site: position = -34 score = 5.07246 sequence = TCGAACAGATGTTCTG Gene: Mvan_2573: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
| ruvA |
Gene: MAB_2883c: Holliday junction DNA helicase RuvA |
Gene: MAV_3474: Holliday junction DNA helicase RuvA |
Gene: Mflv_3825: Holliday junction DNA helicase RuvA |
Gene: ML0482: Holliday junction DNA helicase RuvA |
Gene: MMAR_2110: Holliday junction DNA helicase RuvA |
Gene: MSMEG_2944: Holliday junction DNA helicase RuvA |
Gene: Mjls_2305: Holliday junction DNA helicase RuvA |
Gene: Rv2593c: Holliday junction DNA helicase RuvA |
Gene: Mvan_2574: Holliday junction DNA helicase RuvA |
Holliday junction DNA helicase RuvA |
| ruvB |
Gene: MAB_2882c: Holliday junction DNA helicase RuvB |
Gene: MAV_3473: Holliday junction DNA helicase RuvB |
Gene: Mflv_3824: Holliday junction DNA helicase RuvB |
Gene: ML0483: Holliday junction DNA helicase RuvB |
Gene: MMAR_2111: Holliday junction DNA helicase RuvB |
Gene: MSMEG_2945: Holliday junction DNA helicase RuvB |
Gene: Mjls_2306: Holliday junction DNA helicase RuvB |
Gene: Rv2592c: Holliday junction DNA helicase RuvB |
Gene: Mvan_2575: Holliday junction DNA helicase RuvB |
Holliday junction DNA helicase RuvB |
| CRON 7. | ||||||||||
| Rv3074 |
|
*
Mycobacterium avium 104 Site: position = -23 score = 5.89672 sequence = TCGAACACGTGTTCGA Gene: MAV_3980: Conserved hypothetical protein |
|
|
*
Mycobacterium marinum M Site: position = -8 score = 5.93778 sequence = TCGAACACATGTTCGA Gene: MMAR_1584: Conserved hypothetical protein |
|
|
*
Mycobacterium tuberculosis H37Rv Site: position = -8 score = 5.93778 sequence = TCGAACACATGTTCGA Gene: Rv3074: Conserved hypothetical protein |
|
Conserved hypothetical protein |
| CRON 8. | ||||||||||
| PF02720 |
*
Mycobacterium abscessus ATCC 19977 Site: position = -8 score = 5.32294 sequence = TCAAACGCATGTTCGA Gene: MAB_4752: HNH endonuclease |
|
*2
Mycobacterium flavescens PYR-GCK Site: position = 1 score = 5.27621 sequence = TGGAACACATGTTCGA Gene: Mflv_3422: HNH endonuclease Site: position = -8 score = 5.93778 sequence = TCGAACACATGTTCGA Gene: Mflv_4927: HNH endonuclease |
|
|
*2
Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_5583: HNH endonuclease Site: position = -8 score = 5.46039 sequence = TCGAACGTATGTGCGA Gene: MSMEG_3957: HNH endonuclease |
|
*2
Mycobacterium tuberculosis H37Rv Site: position = -8 score = 5.74296 sequence = TCGAACGTATGTTCGA Gene: Rv3776: HNH endonuclease Gene: Rv2100: HNH endonuclease |
|
HNH endonuclease |
| CRON 9. | ||||||||||
| Rv0336 |
|
*
Mycobacterium avium 104 Site: position = -8 score = 5.69628 sequence = TCGAACATATGTGCGA Gene: MAV_4456: Conserved hypothetical protein |
|
|
*
Mycobacterium marinum M Site: position = -8 score = 5.07302 sequence = TCGAATGTATGTTCGA Gene: MMAR_5187: Conserved hypothetical protein |
|
|
*2
Mycobacterium tuberculosis H37Rv Site: position = -32 score = 5.1767 sequence = TCGAAAGTATGTTCGA Gene: Rv0515: Conserved hypothetical protein Site: position = -32 score = 5.1767 sequence = TCGAAAGTATGTTCGA Gene: Rv0336: Conserved hypothetical protein |
|
Conserved hypothetical protein |
| CRON 10. | ||||||||||
| splB |
*
Mycobacterium abscessus ATCC 19977 Site: position = -24 score = 5.31727 sequence = TCGAACATATGTTCGC Gene: MAB_2868c: DNA repair photolyase |
*
Mycobacterium avium 104 Site: position = -25 score = 5.4381 sequence = TCGAACTGGTGTTCGA Gene: MAV_3456: DNA repair photolyase |
*
Mycobacterium flavescens PYR-GCK Site: position = -23 score = 5.08138 sequence = TCGAACGTATGTTCGC Gene: Mflv_3795: DNA repair photolyase |
|
*
Mycobacterium marinum M Site: position = -25 score = 5.39792 sequence = TCGAACTAGTGTTCGA Gene: MMAR_2148: DNA repair photolyase |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -8 score = 5.70189 sequence = TCGAACGCATGTTCGA Gene: MSMEG_2990: DNA repair photolyase |
*
Mycobacterium sp. JLS Site: position = 35 score = 5.11267 sequence = TCGAACCTACGTTCGA Gene: Mjls_2335: DNA repair photolyase |
*
Mycobacterium tuberculosis H37Rv Site: position = -24 score = 5.125 sequence = TAGAACGGTTGTTCGA Gene: Rv2578c: DNA repair photolyase |
*
Mycobacterium vanbaalenii PYR-1 Site: position = -23 score = 5.08138 sequence = TCGAACGTATGTTCGC Gene: Mvan_2599: DNA repair photolyase |
DNA repair photolyase |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |