Regulog MetJ - Alteromonadales

Properties
Regulator type:	Transcription factor
Regulator family:	MetJ
Regulation mode:	repressor
Biological process:	Methionine metabolism; Methionine biosynthesis
Effector:	S-adenosylmethionine
Phylum:	Proteobacteria/Gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 110 sites [see more]

Member of regulog collections

By taxonomy - Alteromonadales
By trascription factor - MetJ
By TF family - MetJ
By effector - S-adenosylmethionine
By pathway - Methionine metabolism
By pathway - Methionine biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Pseudoalteromonas atlantica T6c	9	7
Alteromonas macleodii 'Deep ecotype'	10	6
Glaciecola sp. HTCC2999	10	6
Colwellia psychrerythraea 34H	14	9
Alteromonadales bacterium TW-7	13	8
Pseudoalteromonas haloplanktis TAC125	14	9
Pseudoalteromonas tunicata D2	19	12
Idiomarina baltica OS145	7	6
Idiomarina loihiensis L2TR	8	7

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
metR	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -83 score = 6.36125 sequence = AGACGTTT-(0)-AAATGGTT Site: position = -91 score = 7.33184 sequence = GGACGTCT-(0)-AGACGTTT Gene: CPS_4359: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Alteromonadales bacterium TW-7 Site: position = -81 score = 6.08992 sequence = AGACGTTG-(0)-AAACGTTT Site: position = -89 score = 6.77558 sequence = AGACGTCT-(0)-AGACGTTG Gene: ATW7_06703: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Pseudoalteromonas haloplanktis TAC125 Site: position = -89 score = 6.1164 sequence = AGCCTTCT-(0)-AGACGTTG Site: position = -81 score = 6.08992 sequence = AGACGTTG-(0)-AAACGTTT Gene: PSHAa1181: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Pseudoalteromonas tunicata D2 Site: position = -375 score = 6.05447 sequence = GGATGTTT-(0)-AGATGGCT Gene: PTD2_22482: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

CRON 2.
metB	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -169 score = 6.37284 sequence = AGAAGTTT-(0)-AGAAGTCT Site: position = -121 score = 5.98668 sequence = AGAGTTAT-(0)-AGACGTCC Site: position = -113 score = 7.19799 sequence = AGACGTCC-(0)-AAACATCT Gene: CPS_0455: Cystathionine gamma-synthase (EC 2.5.1.48)	* Alteromonadales bacterium TW-7 Site: position = -36 score = 7.56226 sequence = AGACGTCT-(0)-AAACATCC Gene: ATW7_17928: Cystathionine gamma-synthase (EC 2.5.1.48)	* Pseudoalteromonas haloplanktis TAC125 Site: position = -36 score = 7.86975 sequence = AGACGTCT-(0)-AAACATCT Gene: PSHAa2723: Cystathionine gamma-synthase (EC 2.5.1.48)	* Pseudoalteromonas tunicata D2 Site: position = -91 score = 6.05606 sequence = AGCTATTT-(0)-AGACGTAT Site: position = -44 score = 6.54815 sequence = AACCTTTT-(0)-AGACGTCT Site: position = -83 score = 6.49919 sequence = AGACGTAT-(0)-AAATGTTT Site: position = -36 score = 7.86975 sequence = AGACGTCT-(0)-AAACATCT Gene: PTD2_16511: Cystathionine gamma-synthase (EC 2.5.1.48)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Cystathionine gamma-synthase (EC 2.5.1.48)
metL	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_0456: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Alteromonadales bacterium TW-7 Gene: ATW7_17933: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa2722: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Pseudoalteromonas tunicata D2 Gene: PTD2_16506: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	* Idiomarina baltica OS145 Site: position = -97 score = 6.62678 sequence = ATCCGTCT-(0)-AGATGGCT Gene: OS145_09128: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	* Idiomarina loihiensis L2TR Site: position = -97 score = 6.62678 sequence = ATCCGTCT-(0)-AGATGGCT Gene: IL2466: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

CRON 3.
metF-II	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -38 score = 7.6773 sequence = AGCCATCT-(0)-AAACGTCT Gene: CPS_0276: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)	* Alteromonadales bacterium TW-7 Site: position = -65 score = 6.57736 sequence = ATCTATCT-(0)-AGACGTCT Site: position = -57 score = 7.30654 sequence = AGACGTCT-(0)-AAATGGCT Gene: ATW7_04247: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)	* Pseudoalteromonas haloplanktis TAC125 Site: position = -68 score = 6.47407 sequence = AGCTATCT-(0)-AGCCATCT Site: position = -60 score = 6.92022 sequence = AGCCATCT-(0)-AAATGGCT Gene: PSHAa0642: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)	* Pseudoalteromonas tunicata D2 Site: position = -58 score = 7.30654 sequence = AGACGTCT-(0)-AAATGGCT Gene: PTD2_08889: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)

CRON 4.
metK	* Pseudoalteromonas atlantica T6c Site: position = -100 score = 7.13131 sequence = AGCCGTTT-(0)-GGACGTCT Gene: Patl_3331: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Alteromonas macleodii 'Deep ecotype' Site: position = -95 score = 7.40748 sequence = AGACTTTT-(0)-AGACGTCT Gene: MADE_03161: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Glaciecola sp. HTCC2999 Site: position = -115 score = 6.94813 sequence = AGACGTCT-(0)-AGATGGTT Site: position = -123 score = 7.50002 sequence = AGACGTAT-(0)-AGACGTCT Gene: GHTCC_010100002529: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Colwellia psychrerythraea 34H Site: position = -100 score = 7.29791 sequence = AGACGTTT-(0)-AGCCGTCT Gene: CPS_1256: S-adenosylmethionine synthetase (EC 2.5.1.6)	Alteromonadales bacterium TW-7 Gene: ATW7_04382: S-adenosylmethionine synthetase (EC 2.5.1.6)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa0670: S-adenosylmethionine synthetase (EC 2.5.1.6)	Pseudoalteromonas tunicata D2 Gene: PTD2_13384: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Idiomarina baltica OS145 Site: position = -99 score = 6.93368 sequence = AGACTTTT-(0)-GGACGTCT Gene: OS145_07801: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Idiomarina loihiensis L2TR Site: position = -99 score = 6.72663 sequence = GGACTTTT-(0)-AGACGTCC Gene: IL2215: S-adenosylmethionine synthetase (EC 2.5.1.6)	S-adenosylmethionine synthetase (EC 2.5.1.6)

CRON 5.
serA	* Pseudoalteromonas atlantica T6c Site: position = -45 score = 7.28817 sequence = AGACGTCC-(0)-AGATGTCT Gene: Patl_1156: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	* Alteromonas macleodii 'Deep ecotype' Site: position = -93 score = 7.95992 sequence = AGACGTCT-(0)-AGATGTCT Gene: MADE_03208: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	* Glaciecola sp. HTCC2999 Site: position = -46 score = 7.95992 sequence = AGACGTCT-(0)-AGATGTCT Site: position = -54 score = 6.1038 sequence = AAGCATTT-(0)-AGACGTCT Gene: GHTCC_010100002789: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	* Colwellia psychrerythraea 34H Site: position = -64 score = 6.70484 sequence = AGATATCT-(0)-AGCCATCT Gene: CPS_1544: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	Alteromonadales bacterium TW-7 Gene: ATW7_04362: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa0666: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	Pseudoalteromonas tunicata D2 Gene: PTD2_12904: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	Idiomarina baltica OS145 Gene: OS145_04268: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	Idiomarina loihiensis L2TR Gene: IL2104: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)

CRON 6.
metA	* Pseudoalteromonas atlantica T6c Site: position = -88 score = 6.2221 sequence = TTACGTTT-(0)-AGACGTCT Site: position = -80 score = 6.571 sequence = AGACGTCT-(0)-AGACGTAA Gene: Patl_3021: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Alteromonas macleodii 'Deep ecotype' Site: position = -81 score = 6.571 sequence = AGACGTCT-(0)-AGACGTAA Site: position = -89 score = 7.20732 sequence = AAACGTTT-(0)-AGACGTCT Gene: MADE_02861: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Glaciecola sp. HTCC2999 Site: position = -78 score = 7.50064 sequence = AGACGTCT-(0)-AGACGTAT Site: position = -86 score = 7.83589 sequence = AGACGTTT-(0)-AGACGTCT Gene: GHTCC_010100000045: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Colwellia psychrerythraea 34H Site: position = -92 score = 7.18127 sequence = AGACGTCT-(0)-ATACGTTT Gene: CPS_1100: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Alteromonadales bacterium TW-7 Site: position = -82 score = 7.36984 sequence = AGACATCT-(0)-ATACATCT Gene: ATW7_10333: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Pseudoalteromonas haloplanktis TAC125 Site: position = -82 score = 6.83186 sequence = AGACATCT-(0)-ATCCATCT Site: position = -90 score = 6.46214 sequence = GGATATTT-(0)-AGACATCT Gene: PSHAa2224: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Pseudoalteromonas tunicata D2 Site: position = -83 score = 7.7142 sequence = AGACATCT-(0)-AAACATCT Gene: PTD2_08609: Homoserine O-succinyltransferase (EC 2.3.1.46)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Homoserine O-succinyltransferase (EC 2.3.1.46)
metH2	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype' Gene: MADE_02860: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Glaciecola sp. HTCC2999 Gene: GHTCC_010100000040: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7 Gene: ATW7_10328: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa2223: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Pseudoalteromonas tunicata D2 Gene: PTD2_08614: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metH	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype' Gene: MADE_02859: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Glaciecola sp. HTCC2999 Gene: GHTCC_010100000035: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Colwellia psychrerythraea 34H Gene: CPS_1101: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Alteromonadales bacterium TW-7 Gene: ATW7_10323: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa2222: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Pseudoalteromonas tunicata D2 Gene: PTD2_08619: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

CRON 7.
metJ	* Pseudoalteromonas atlantica T6c Site: position = -126 score = 7.46252 sequence = GGACGTTT-(0)-AGACGTCT Site: position = -90 score = 6.16276 sequence = AGCCGTCA-(0)-AGATGTTT Gene: Patl_3956: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Alteromonas macleodii 'Deep ecotype' Site: position = -132 score = 7.83589 sequence = AGACGTTT-(0)-AGACGTCT Site: position = -96 score = 5.99121 sequence = AGACGTCA-(0)-AGAGGTTT Gene: MADE_03523: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Glaciecola sp. HTCC2999 Site: position = -122 score = 7.83589 sequence = AGACGTTT-(0)-AGACGTCT Gene: GHTCC_010100003244: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Colwellia psychrerythraea 34H Site: position = -143 score = 6.12205 sequence = GGACGTCT-(0)-ATAACTCT Site: position = -95 score = 6.75633 sequence = AGACTTCT-(0)-AAACTTCT Site: position = -151 score = 6.71112 sequence = AGATGTTT-(0)-GGACGTCT Gene: CPS_0454: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Alteromonadales bacterium TW-7 Site: position = -140 score = 5.65239 sequence = AGATGTCA-(0)-AAACATTT Site: position = -179 score = 6.81155 sequence = GGATGTTT-(0)-AGACGTCT Gene: ATW7_17923: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Pseudoalteromonas haloplanktis TAC125 Site: position = -179 score = 7.18492 sequence = AGATGTTT-(0)-AGACGTCT Site: position = -124 score = 5.92899 sequence = AAACACCT-(0)-AGCCATCT Gene: PSHAa2724: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Pseudoalteromonas tunicata D2 Site: position = -224 score = 7.18492 sequence = AGATGTTT-(0)-AGACGTCT Site: position = -177 score = 6.52784 sequence = AAACATTT-(0)-ATACGTCT Site: position = -169 score = 6.48411 sequence = ATACGTCT-(0)-AAATAGCT Site: position = -216 score = 6.36624 sequence = AGACGTCT-(0)-AAAAGGTT Gene: PTD2_16516: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Idiomarina baltica OS145 Site: position = -93 score = 6.64052 sequence = AGCCATCT-(0)-AGACGGAT Gene: OS145_09123: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Idiomarina loihiensis L2TR Site: position = -93 score = 6.64052 sequence = AGCCATCT-(0)-AGACGGAT Gene: IL2465: S-adenosylmethionine-responsive transcriptional repressor MetJ	S-adenosylmethionine-responsive transcriptional repressor MetJ

CRON 8.
metT	* Pseudoalteromonas atlantica T6c Site: position = -27 score = 7.75613 sequence = AGACGTCT-(0)-AAACGTCC Gene: Patl_1376: Methionine transporter MetT, NhaC antiporter family	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -79 score = 7.48343 sequence = AGCCATCT-(0)-AAACATCT Site: position = -87 score = 6.00051 sequence = AGTCATTT-(0)-AGCCATCT Gene: CPS_3465: Methionine transporter MetT, NhaC antiporter family	* Alteromonadales bacterium TW-7 Site: position = -156 score = 5.68583 sequence = ATACATTT-(0)-AAACTTCC Site: position = -164 score = 6.60109 sequence = AGCCATCT-(0)-ATACATTT Gene: ATW7_06968: Methionine transporter MetT, NhaC antiporter family	* Pseudoalteromonas haloplanktis TAC125 Site: position = -148 score = 5.99332 sequence = ATACATTT-(0)-AAACTTCT Site: position = -156 score = 6.75663 sequence = AGCCGTCT-(0)-ATACATTT Gene: PSHAa1226: Methionine transporter MetT, NhaC antiporter family	* Pseudoalteromonas tunicata D2 Site: position = -125 score = 6.2936 sequence = AGCCATCT-(0)-ATACATTC Site: position = -133 score = 6.72724 sequence = AAACATCT-(0)-AGCCATCT Gene: PTD2_10704: Methionine transporter MetT, NhaC antiporter family	* Idiomarina baltica OS145 Site: position = -50 score = 6.71242 sequence = AAACTTCT-(0)-GGACGTCT Site: position = -58 score = 5.40429 sequence = AGCTATAT-(0)-AAACTTCT Gene: OS145_08567: Methionine transporter MetT, NhaC antiporter family	* Idiomarina loihiensis L2TR Site: position = -40 score = 6.40494 sequence = AAACTTCT-(0)-GGACGTCC Site: position = -48 score = 5.55983 sequence = AGCTGTAT-(0)-AAACTTCT Gene: IL2378: Methionine transporter MetT, NhaC antiporter family	Methionine transporter MetT, NhaC antiporter family

CRON 9.
metF	* Pseudoalteromonas atlantica T6c Site: position = -36 score = 7.75613 sequence = AGACGTCT-(0)-AAACGTCC Site: position = -80 score = 6.6431 sequence = AGACTGCT-(0)-AAACATCT Gene: Patl_3955: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Alteromonas macleodii 'Deep ecotype' Site: position = -45 score = 8.06362 sequence = AGACGTCT-(0)-AAACGTCT Site: position = -73 score = 6.32155 sequence = TGACGTCT-(0)-AGACATAT Gene: MADE_03524: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Glaciecola sp. HTCC2999 Site: position = -46 score = 8.06362 sequence = AGACGTCT-(0)-AAACGTCT Gene: GHTCC_010100003239: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

CRON 10.
COG0235	Pseudoalteromonas atlantica T6c Gene: Patl_1685: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	Alteromonas macleodii 'Deep ecotype' Gene: MADE_01738: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	Glaciecola sp. HTCC2999 Gene: GHTCC_010100005477: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	Colwellia psychrerythraea 34H Gene: CPS_1172: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	* Alteromonadales bacterium TW-7 Site: position = -54 score = 7.44134 sequence = AGACTTCT-(0)-AAACATCT Gene: ATW7_14626: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	* Pseudoalteromonas haloplanktis TAC125 Site: position = -54 score = 7.44134 sequence = AGACTTCT-(0)-AAACATCT Gene: PSHAa0286: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	* Pseudoalteromonas tunicata D2 Site: position = -85 score = 6.29114 sequence = AGACTTCT-(0)-ACACTTCT Gene: PTD2_06859: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
COG4948	Pseudoalteromonas atlantica T6c Gene: Patl_1686: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	Alteromonas macleodii 'Deep ecotype' Gene: MADE_01739: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	Glaciecola sp. HTCC2999 Gene: GHTCC_010100005472: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	Colwellia psychrerythraea 34H Gene: CPS_1173: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	Alteromonadales bacterium TW-7 Gene: ATW7_14621: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa0287: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	Pseudoalteromonas tunicata D2 Gene: PTD2_06864: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

CRON 11.
thrA	* Pseudoalteromonas atlantica T6c Site: position = -239 score = 6.31581 sequence = AGACGTCT-(0)-ATACGGCA Site: position = -247 score = 6.35926 sequence = TGACATAT-(0)-AGACGTCT Site: position = -262 score = 7.23141 sequence = AGACGTCT-(0)-AGACGGTT Gene: Patl_3580: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	* Alteromonas macleodii 'Deep ecotype' Site: position = -242 score = 6.31581 sequence = AGACGTCT-(0)-ATACGGCA Site: position = -250 score = 6.0864 sequence = TGACTTAT-(0)-AGACGTCT Gene: MADE_03328: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	* Glaciecola sp. HTCC2999 Site: position = -188 score = 6.69512 sequence = TGACATTT-(0)-AGACGTCT Site: position = -180 score = 6.31581 sequence = AGACGTCT-(0)-ATACGGCA Gene: GHTCC_010100002414: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Colwellia psychrerythraea 34H Gene: CPS_4291: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Alteromonadales bacterium TW-7 Gene: ATW7_11055: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa2379: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Pseudoalteromonas tunicata D2 Gene: PTD2_12584: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
thrB	Pseudoalteromonas atlantica T6c Gene: Patl_3579: Homoserine kinase (EC 2.7.1.39)	Alteromonas macleodii 'Deep ecotype' Gene: MADE_03327: Homoserine kinase (EC 2.7.1.39)	Glaciecola sp. HTCC2999 Gene: GHTCC_010100002419: Homoserine kinase (EC 2.7.1.39)	Colwellia psychrerythraea 34H Gene: CPS_4290: Homoserine kinase (EC 2.7.1.39)	Alteromonadales bacterium TW-7 Gene: ATW7_11050: Homoserine kinase (EC 2.7.1.39)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa2378: Homoserine kinase (EC 2.7.1.39)	Pseudoalteromonas tunicata D2 Gene: PTD2_12579: Homoserine kinase (EC 2.7.1.39)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Homoserine kinase (EC 2.7.1.39)
thrC	Pseudoalteromonas atlantica T6c Gene: Patl_3578: Threonine synthase (EC 4.2.3.1)	Alteromonas macleodii 'Deep ecotype' Gene: MADE_03326: Threonine synthase (EC 4.2.3.1)	Glaciecola sp. HTCC2999 Gene: GHTCC_010100002424: Threonine synthase (EC 4.2.3.1)	Colwellia psychrerythraea 34H Gene: CPS_4289: Threonine synthase (EC 4.2.3.1)	Alteromonadales bacterium TW-7 Gene: ATW7_11045: Threonine synthase (EC 4.2.3.1)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa2377: Threonine synthase (EC 4.2.3.1)	Pseudoalteromonas tunicata D2 Gene: PTD2_12574: Threonine synthase (EC 4.2.3.1)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Threonine synthase (EC 4.2.3.1)

CRON 12.
metX	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	* Idiomarina baltica OS145 Site: position = -77 score = 7.49638 sequence = GGACGTCT-(0)-AAACATCT Gene: OS145_04750: Homoserine O-acetyltransferase (EC 2.3.1.31)	* Idiomarina loihiensis L2TR Site: position = -67 score = 5.6938 sequence = AAATGTCT-(0)-TGACGTCC Site: position = -75 score = 7.40697 sequence = GGACGTCT-(0)-AAATGTCT Gene: IL2013: Homoserine O-acetyltransferase (EC 2.3.1.31)	Homoserine O-acetyltransferase (EC 2.3.1.31)
metY	Pseudoalteromonas atlantica T6c Gene: Patl_3406: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999 Gene: GHTCC_010100007942: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)	Colwellia psychrerythraea 34H Gene: CPS_2546: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)	Alteromonadales bacterium TW-7 Gene: ATW7_00225: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAb0477: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145 Gene: OS145_04755: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)	Idiomarina loihiensis L2TR Gene: IL2014: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)	O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)

CRON 13.
PF08908	Pseudoalteromonas atlantica T6c Gene: Patl_0920: Protein of unknown function DUF1852	Alteromonas macleodii 'Deep ecotype' Gene: MADE_01037: Protein of unknown function DUF1852	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1152: Protein of unknown function DUF1852	* Alteromonadales bacterium TW-7 Site: position = -245 score = 7.31019 sequence = AGAAATCT-(0)-AGACGTCT Gene: ATW7_00705: Protein of unknown function DUF1852	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa1471: Protein of unknown function DUF1852	* Pseudoalteromonas tunicata D2 Site: position = -228 score = 6.618 sequence = AGACATCT-(0)-AGATTTCC Gene: PTD2_14897: Protein of unknown function DUF1852	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Protein of unknown function DUF1852
metE2	Pseudoalteromonas atlantica T6c Gene: Patl_0921: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Alteromonas macleodii 'Deep ecotype' Gene: MADE_01036: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1151: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Alteromonadales bacterium TW-7 Gene: ATW7_00710: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa1470: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Pseudoalteromonas tunicata D2 Gene: PTD2_14892: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

CRON 14.
msrA	Pseudoalteromonas atlantica T6c Gene: Patl_4063: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Alteromonas macleodii 'Deep ecotype' Gene: MADE_03638: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Glaciecola sp. HTCC2999 Gene: GHTCC_010100007352: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Colwellia psychrerythraea 34H Gene: CPS_4817: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	* Idiomarina baltica OS145 Site: position = -32 score = 6.53336 sequence = AGCCTTAT-(0)-AGACGTCC Gene: OS145_04880: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	* Idiomarina loihiensis L2TR Site: position = -39 score = 7.11371 sequence = AGCCATAT-(0)-AGACGTCT Gene: IL2039: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)

CRON 15.
mtnB	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	* Pseudoalteromonas haloplanktis TAC125 Site: position = -52 score = 6.52045 sequence = AGAAGTTT-(0)-AGCCGTCT Gene: PSHAa2922: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)	* Pseudoalteromonas tunicata D2 Site: position = -35 score = 6.11721 sequence = AGATGTAT-(0)-AGCCATCT Gene: PTD2_09374: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
mtnC	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2 Gene: PTD2_09379: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
mtnD	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2 Gene: PTD2_09384: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)

CRON 16.
btuB2	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145	* Idiomarina loihiensis L2TR Site: position = -42 score = 7.58981 sequence = AGACGTCT-(0)-AAACGGCT Site: position = -50 score = 7.60512 sequence = AGCCGTTT-(0)-AGACGTCT Gene: IL2488: TonB-dependent outer membrane transporter for vitamin B12	TonB-dependent outer membrane transporter for vitamin B12

CRON 17.
btuD	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -217 score = 7.48343 sequence = AGCCATCT-(0)-AAACATCT Gene: CPS_1166: Vitamin B12 ABC transporter, ATPase component BtuD	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Vitamin B12 ABC transporter, ATPase component BtuD
btuC	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1165: Vitamin B12 ABC transporter, permease component BtuC	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Vitamin B12 ABC transporter, permease component BtuC
pduO	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1164: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
btuF	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1163: Vitamin B12 ABC transporter, B12-binding component BtuF	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Vitamin B12 ABC transporter, B12-binding component BtuF

CRON 18.
metE	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	* Pseudoalteromonas tunicata D2 Site: position = -36 score = 7.17595 sequence = AGCCATCT-(0)-AAACATCC Gene: PTD2_22477: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

CRON 19.
mtnK	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	* Pseudoalteromonas tunicata D2 Site: position = -60 score = 5.84047 sequence = GGACATCT-(0)-AAACACTT Site: position = -68 score = 6.79806 sequence = AGAAGTCT-(0)-GGACATCT Gene: PTD2_09409: 5-methylthioribose kinase (EC 2.7.1.100)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	5-methylthioribose kinase (EC 2.7.1.100)

CRON 20.
PSHAa2276	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	* Pseudoalteromonas haloplanktis TAC125 Site: position = -17 score = 6.08938 sequence = GGCTATAT-(0)-AGACGTCT Gene: PSHAa2276: putative orphan protein	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	putative orphan protein
btuB	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1162: TonB-dependent outer membrane transporter for vitamin B12	Alteromonadales bacterium TW-7 Gene: ATW7_10608: TonB-dependent outer membrane transporter for vitamin B12	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAa2275: TonB-dependent outer membrane transporter for vitamin B12	* Pseudoalteromonas tunicata D2 Site: position = -313 score = 7.12678 sequence = AGACATCT-(0)-GAACGTCC Gene: PTD2_14279: TonB-dependent outer membrane transporter for vitamin B12	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	TonB-dependent outer membrane transporter for vitamin B12

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog MetJ - Alteromonadales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --