Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Pseudoalteromonas tunicata D2

Properties
Regulator type: Transcription factor
TF locus tag: PTD2_16516
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine metabolism; Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: MetJ - Alteromonadales
Statistics of regulated genes:
- Genes 19
- Operons 12
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 110 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -228
Score: 6.6
Sequence: AGACATCT-(0)-AGATTTCC
Locus tag: PTD2_14897
Name: PF08908
Funciton: Protein of unknown function DUF1852
Locus tag: PTD2_14892
Name: metE2
Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
PF08908
Protein of unknown function DUF1852
metE2
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

Position: -224
Score: 7.2
Sequence: AGATGTTT-(0)-AGACGTCT
Position: -216
Score: 6.4
Sequence: AGACGTCT-(0)-AAAAGGTT
Position: -177
Score: 6.5
Sequence: AAACATTT-(0)-ATACGTCT
Position: -169
Score: 6.5
Sequence: ATACGTCT-(0)-AAATAGCT
Locus tag: PTD2_16516
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ

Position: -83
Score: 7.7
Sequence: AGACATCT-(0)-AAACATCT
Locus tag: PTD2_08609
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
Locus tag: PTD2_08614
Name: metH2
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
Locus tag: PTD2_08619
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)
metH2
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Position: -85
Score: 6.3
Sequence: AGACTTCT-(0)-ACACTTCT
Locus tag: PTD2_06859
Name: COG0235
Funciton: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
Locus tag: PTD2_06864
Name: COG4948
Funciton: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
COG0235
Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
COG4948
L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Position: -133
Score: 6.7
Sequence: AAACATCT-(0)-AGCCATCT
Position: -125
Score: 6.3
Sequence: AGCCATCT-(0)-ATACATTC
Locus tag: PTD2_10704
Name: metT
Funciton: Methionine transporter MetT, NhaC antiporter family
metT
Methionine transporter MetT, NhaC antiporter family

Position: -91
Score: 6.1
Sequence: AGCTATTT-(0)-AGACGTAT
Position: -83
Score: 6.5
Sequence: AGACGTAT-(0)-AAATGTTT
Position: -44
Score: 6.5
Sequence: AACCTTTT-(0)-AGACGTCT
Position: -36
Score: 7.9
Sequence: AGACGTCT-(0)-AAACATCT
Locus tag: PTD2_16511
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: PTD2_16506
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

Position: -375
Score: 6.1
Sequence: GGATGTTT-(0)-AGATGGCT
Locus tag: PTD2_22482
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -313
Score: 7.1
Sequence: AGACATCT-(0)-GAACGTCC
Locus tag: PTD2_14279
Name: btuB
Funciton: TonB-dependent outer membrane transporter for vitamin B12
btuB
TonB-dependent outer membrane transporter for vitamin B12

Position: -68
Score: 6.8
Sequence: AGAAGTCT-(0)-GGACATCT
Position: -60
Score: 5.8
Sequence: GGACATCT-(0)-AAACACTT
Locus tag: PTD2_09409
Name: mtnK
Funciton: 5-methylthioribose kinase (EC 2.7.1.100)
mtnK
5-methylthioribose kinase (EC 2.7.1.100)

Position: -36
Score: 7.2
Sequence: AGCCATCT-(0)-AAACATCC
Locus tag: PTD2_22477
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -58
Score: 7.3
Sequence: AGACGTCT-(0)-AAATGGCT
Locus tag: PTD2_08889
Name: metF-II
Funciton: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)
metF-II
5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)

Position: -35
Score: 6.1
Sequence: AGATGTAT-(0)-AGCCATCT
Locus tag: PTD2_09374
Name: mtnB
Funciton: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
Locus tag: PTD2_09379
Name: mtnC
Funciton: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
Locus tag: PTD2_09384
Name: mtnD
Funciton: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
mtnB
Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
mtnC
2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
mtnD
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
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