Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Alteromonadales bacterium TW-7

Properties
Regulator type: Transcription factor
TF locus tag: ATW7_17923
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine metabolism; Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: MetJ - Alteromonadales
Statistics of regulated genes:
- Genes 13
- Operons 8
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 110 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -179
Score: 6.8
Sequence: GGATGTTT-(0)-AGACGTCT
Position: -140
Score: 5.7
Sequence: AGATGTCA-(0)-AAACATTT
Locus tag: ATW7_17923
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ

Position: -82
Score: 7.4
Sequence: AGACATCT-(0)-ATACATCT
Locus tag: ATW7_10333
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
Locus tag: ATW7_10328
Name: metH2
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
Locus tag: ATW7_10323
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)
metH2
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Position: -89
Score: 6.8
Sequence: AGACGTCT-(0)-AGACGTTG
Position: -81
Score: 6.1
Sequence: AGACGTTG-(0)-AAACGTTT
Locus tag: ATW7_06703
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -54
Score: 7.4
Sequence: AGACTTCT-(0)-AAACATCT
Locus tag: ATW7_14626
Name: COG0235
Funciton: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
Locus tag: ATW7_14621
Name: COG4948
Funciton: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
COG0235
Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
COG4948
L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Position: -164
Score: 6.6
Sequence: AGCCATCT-(0)-ATACATTT
Position: -156
Score: 5.7
Sequence: ATACATTT-(0)-AAACTTCC
Locus tag: ATW7_06968
Name: metT
Funciton: Methionine transporter MetT, NhaC antiporter family
metT
Methionine transporter MetT, NhaC antiporter family

Position: -36
Score: 7.6
Sequence: AGACGTCT-(0)-AAACATCC
Locus tag: ATW7_17928
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: ATW7_17933
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

Position: -65
Score: 6.6
Sequence: ATCTATCT-(0)-AGACGTCT
Position: -57
Score: 7.3
Sequence: AGACGTCT-(0)-AAATGGCT
Locus tag: ATW7_04247
Name: metF-II
Funciton: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)
metF-II
5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)

Position: -245
Score: 7.3
Sequence: AGAAATCT-(0)-AGACGTCT
Locus tag: ATW7_00705
Name: PF08908
Funciton: Protein of unknown function DUF1852
Locus tag: ATW7_00710
Name: metE2
Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
PF08908
Protein of unknown function DUF1852
metE2
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
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