Regulog Rex - Clostridia-3

Properties
Regulator type:	Transcription factor
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 121 sites [see more]

Member of regulog collections

By taxonomy - Clostridia-3
By TF family - Rex
By effector - NADH
By pathway - Energy metabolism

Statistics of regulated genes
Genome	Genes	Operons
Bacteroides pectinophilus ATCC 43243	9	8
Blautia hansenii DSM 20583	3	3
Bryantella formatexigens DSM 14469	2	2
Clostridiales bacterium 1_7_47_FAA	17	14
Clostridium bolteae ATCC BAA-613	17	11
Clostridium nexile DSM 1787	6	4
Clostridium scindens ATCC 35704	2	2
Dorea formicigenerans ATCC 27755	10	9
Dorea longicatena DSM 13814	5	5
Eubacterium eligens ATCC 27750	12	10
Eubacterium rectale ATCC 33656	12	10
Roseburia intestinalis L1-82	12	9
Ruminococcus gnavus ATCC 29149	8	5
Ruminococcus lactaris ATCC 29176	9	7

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes															Function

CRON 1.
pgpB	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469 Gene: BRYFOR_02184: putative phosphatidylglycerophosphatase B	* Clostridiales bacterium 1_7_47_FAA Site: position = -86 score = 5.25806 sequence = TTGTGAAAATATTAACAT Gene: Cbac1_010100019049: putative phosphatidylglycerophosphatase B	* Clostridium bolteae ATCC BAA-613 Site: position = -81 score = 5.38919 sequence = TTGTTAAAATATTAACAG Gene: CLOBOL_05166: putative phosphatidylglycerophosphatase B	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656 Gene: EUBREC_1572: putative phosphatidylglycerophosphatase B	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	putative phosphatidylglycerophosphatase B
COG491	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100019054: Zn-dependent hydrolase	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05167: Zn-dependent hydrolase	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	Zn-dependent hydrolase

CRON 2.
pncB	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583 Gene: BLAHAN_00705: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_03226: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Clostridiales bacterium 1_7_47_FAA Site: position = -140 score = 5.57491 sequence = TTGTTATATTTTTAACAT Gene: Cbac1_010100002579: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Clostridium bolteae ATCC BAA-613 Site: position = -141 score = 5.5457 sequence = TTGTTAAATTTTTATCAT Gene: CLOBOL_06020: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Clostridium nexile DSM 1787 Gene: CLONEX_02528: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Clostridium scindens ATCC 35704 Gene: CLOSCI_03141: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01810: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Dorea longicatena DSM 13814 Gene: DORLON_01284: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Eubacterium eligens ATCC 27750 Gene: EUBELI_00163: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82 Gene: ROSINTL182_01354: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01334: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_02731: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Nicotinate phosphoribosyltransferase (EC 2.4.2.11)

CRON 3.
aroE	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	* Clostridium nexile DSM 1787 Site: position = -63 score = 5.48508 sequence = TTGTTTAAAATTTAACAA Gene: CLONEX_00392: Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282)	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	* Dorea longicatena DSM 13814 Site: position = -53 score = 4.79697 sequence = TTGTTAAAATATAAGCAA Gene: DORLON_00700: Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282)	Eubacterium eligens ATCC 27750	* Eubacterium rectale ATCC 33656 Site: position = -98 score = 5.04509 sequence = TTGTTAAGTTTTTAACGA Gene: EUBREC_2843: Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282)	* Roseburia intestinalis L1-82 Site: position = -90 score = 5.37277 sequence = TTGTTAAGTTTTTAACAA Gene: ROSINTL182_01690: Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282)	Ruminococcus gnavus ATCC 29149	* Ruminococcus lactaris ATCC 29176 Site: position = -111 score = 4.79984 sequence = TTGTTTGATAATTAACAA Gene: RUMLAC_00224: Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282)	Shikimate/quinate 5-dehydrogenase I beta (EC 1.1.1.282)
kefA	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787 Gene: CLONEX_00391: potassium efflux system KefA	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656 Gene: EUBREC_2842: potassium efflux system KefA	Roseburia intestinalis L1-82 Gene: ROSINTL182_01691: potassium efflux system KefA	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00223: potassium efflux system KefA	potassium efflux system KefA
aroD	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01386: 3-dehydroquinate dehydratase I (EC 4.2.1.10)	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100025132: 3-dehydroquinate dehydratase I (EC 4.2.1.10)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_00527: 3-dehydroquinate dehydratase I (EC 4.2.1.10)	Clostridium nexile DSM 1787 Gene: CLONEX_00390: 3-dehydroquinate dehydratase I (EC 4.2.1.10)	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656 Gene: EUBREC_2841: 3-dehydroquinate dehydratase I (EC 4.2.1.10)	2 Roseburia intestinalis L1-82 Gene: ROSINTL182_01693: 3-dehydroquinate dehydratase I (EC 4.2.1.10) Gene: ROSINTL182_01692: 3-dehydroquinate dehydratase I (EC 4.2.1.10)	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00222: 3-dehydroquinate dehydratase I (EC 4.2.1.10)	3-dehydroquinate dehydratase I (EC 4.2.1.10)

CRON 4.
phf1	* Bacteroides pectinophilus ATCC 43243 Site: position = -57 score = 4.83523 sequence = GTGTGAAAATATTAACAT Gene: BACPEC_01128: [Fe] hydrogenase (EC 1.12.7.2)	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -106 score = 5.48162 sequence = TTGATATAAAATTAACAA Gene: Cbac1_010100009193: [Fe] hydrogenase (EC 1.12.7.2)	* Clostridium bolteae ATCC BAA-613 Site: position = -61 score = 5.56061 sequence = TTGATATAATTTTAACAA Gene: CLOBOL_05631: [Fe] hydrogenase (EC 1.12.7.2)	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	* Eubacterium eligens ATCC 27750 Site: position = -40 score = 4.76377 sequence = TCGATAATTTTTTGTCAA Gene: EUBELI_01405: [Fe] hydrogenase (EC 1.12.7.2)	* Eubacterium rectale ATCC 33656 Site: position = -219 score = 5.26852 sequence = TTGTGAAAAAAATAACAA Gene: EUBREC_2390: [Fe] hydrogenase (EC 1.12.7.2)	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	[Fe] hydrogenase (EC 1.12.7.2)

CRON 5.
ppsA	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583 Gene: BLAHAN_01698: Pyruvate,phosphate dikinase (EC 2.7.9.1)	2 Bryantella formatexigens DSM 14469 Gene: BRYFOR_02578: Pyruvate,phosphate dikinase (EC 2.7.9.1) Gene: BRYFOR_02579: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100007203: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_06339: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Clostridium nexile DSM 1787 Gene: CLONEX_03647: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01563: Pyruvate,phosphate dikinase (EC 2.7.9.1)	* Dorea formicigenerans ATCC 27755 Site: position = -148 score = 5.19744 sequence = TTGACAAAAATATAACAA Gene: DORFOR_02389: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Dorea longicatena DSM 13814 Gene: DORLON_01118: Pyruvate,phosphate dikinase (EC 2.7.9.1)	* Eubacterium eligens ATCC 27750 Site: position = -71 score = 5.57714 sequence = ATGTTATAATTTTAACAA Gene: EUBELI_01258: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1857: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Roseburia intestinalis L1-82 Gene: ROSINTL182_03178: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_03434: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00603: Pyruvate,phosphate dikinase (EC 2.7.9.1)	Pyruvate,phosphate dikinase (EC 2.7.9.1)

CRON 6.
fba	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_00474: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Blautia hansenii DSM 20583 Gene: BLAHAN_03153: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -39 score = 5.24363 sequence = TAGTTAATAAAATAACAA Gene: Cbac1_010100011950: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Clostridium bolteae ATCC BAA-613 Site: position = -37 score = 5.24363 sequence = TAGTTAATAAAATAACAA Gene: CLOBOL_02749: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Clostridium nexile DSM 1787 Gene: CLONEX_01175: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Clostridium scindens ATCC 35704 Gene: CLOSCI_02348: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Dorea formicigenerans ATCC 27755 Site: position = -125 score = 5.04845 sequence = TTGTTAAAAATATGACGA Gene: DORFOR_01112: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Dorea longicatena DSM 13814 Gene: DORLON_00078: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Eubacterium eligens ATCC 27750 Gene: EUBELI_01833: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Eubacterium rectale ATCC 33656 Site: position = -78 score = 4.96164 sequence = GTGTTAAAAATTTAACTT Gene: EUBREC_0700: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Roseburia intestinalis L1-82 Site: position = -86 score = 5.23499 sequence = TTGTTATAAATTTAACTT Gene: ROSINTL182_02682: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01624: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_01363: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Fructose-bisphosphate aldolase class II (EC 4.1.2.13)

CRON 7.
pckA	* Bacteroides pectinophilus ATCC 43243 Site: position = -135 score = 5.22024 sequence = TCGTTAAAATTTTATCAT Gene: BACPEC_01917: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	* Blautia hansenii DSM 20583 Site: position = -179 score = 5.1574 sequence = TCGTTAAATTTTAAACAA Gene: BLAHAN_02079: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	* Bryantella formatexigens DSM 14469 Site: position = -140 score = 5.24269 sequence = TTGTTAATAAAATATCAT Gene: BRYFOR_04079: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	* Clostridiales bacterium 1_7_47_FAA Site: position = -69 score = 4.64021 sequence = TTGACTTTTAATTAACAA Gene: Cbac1_010100026864: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_00502: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	Clostridium nexile DSM 1787 Gene: CLONEX_03201: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	Clostridium scindens ATCC 35704 Gene: CLOSCI_03565: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	* Dorea formicigenerans ATCC 27755 Site: position = -118 score = 4.79698 sequence = TTGTTAAAAATTTATTGA Gene: DORFOR_01796: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	Dorea longicatena DSM 13814 Gene: DORLON_01077: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	* Eubacterium eligens ATCC 27750 Site: position = -110 score = 4.98838 sequence = TCGAGAAAAATTTAACAA Gene: EUBELI_01169: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	* Eubacterium rectale ATCC 33656 Site: position = -82 score = 5.08014 sequence = TTGATTTTTTTTTAACAA Gene: EUBREC_2002: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	* Roseburia intestinalis L1-82 Site: position = -90 score = 4.95851 sequence = TTGACAAAAAAATAACAT Gene: ROSINTL182_03866: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01556: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00832: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)	Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)

CRON 8.
ladH	* Bacteroides pectinophilus ATCC 43243 Site: position = -55 score = 4.89364 sequence = GTGTTATAATTTTAACAG Gene: BACPEC_00707: Lactaldehyde reductase (EC 1.1.1.77)	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -81 score = 5.66254 sequence = TTGTTATAATATTAACAA Gene: Cbac1_010100016333: Lactaldehyde reductase (EC 1.1.1.77)	* Clostridium bolteae ATCC BAA-613 Site: position = -92 score = 5.66254 sequence = TTGTTATAATATTAACAA Gene: CLOBOL_03318: Lactaldehyde reductase (EC 1.1.1.77)	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704 Gene: CLOSCI_03784: Lactaldehyde reductase (EC 1.1.1.77)	* Dorea formicigenerans ATCC 27755 Site: position = -57 score = 5.0989 sequence = TTGTTAAAATAAAAACAT Gene: DORFOR_00826: Lactaldehyde reductase (EC 1.1.1.77)	* Dorea longicatena DSM 13814 Site: position = -231 score = 5.00652 sequence = AAGTTATTTATATAACAA Site: position = -102 score = 4.73796 sequence = TTGTTAAAATAAAGACAT Gene: DORLON_02552: Lactaldehyde reductase (EC 1.1.1.77)	* Eubacterium eligens ATCC 27750 Site: position = -170 score = 4.994 sequence = TTGTTATAAGTATAACAT Site: position = -78 score = 4.96073 sequence = TTGTTATTATTTTGTCAT Gene: EUBELI_20348: Lactaldehyde reductase (EC 1.1.1.77)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1091: Lactaldehyde reductase (EC 1.1.1.77)	2 Roseburia intestinalis L1-82 Gene: ROSINTL182_02299: Lactaldehyde reductase (EC 1.1.1.77) Gene: ROSINTL182_04795: Lactaldehyde reductase (EC 1.1.1.77)	* Ruminococcus gnavus ATCC 29149 Site: position = -33 score = 4.82404 sequence = TTGTTAAAATCAAAACAA Gene: RUMGNA_02449: Lactaldehyde reductase (EC 1.1.1.77)	* Ruminococcus lactaris ATCC 29176 Site: position = -67 score = 4.73796 sequence = TTGTTAAAATAAAGACAT Gene: RUMLAC_00614: Lactaldehyde reductase (EC 1.1.1.77)	Lactaldehyde reductase (EC 1.1.1.77)

CRON 9.
gap	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_01590: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Blautia hansenii DSM 20583 Gene: BLAHAN_03011: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01251: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Clostridiales bacterium 1_7_47_FAA Site: position = -54 score = 5.2274 sequence = TTGATTATTATTTAACAA Gene: Cbac1_010100019254: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Clostridium bolteae ATCC BAA-613 Site: position = -54 score = 5.30416 sequence = TTGATTAATATTTAACAA Gene: CLOBOL_05214: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Clostridium nexile DSM 1787 Gene: CLONEX_03007: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01404: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Dorea formicigenerans ATCC 27755 Site: position = -89 score = 4.65237 sequence = TTGATGAATCTTTAACAA Gene: DORFOR_01431: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Dorea longicatena DSM 13814 Gene: DORLON_02437: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Eubacterium eligens ATCC 27750 Site: position = -57 score = 4.97365 sequence = TAGTTGAAATTTTAACAA Gene: EUBELI_01190: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Eubacterium rectale ATCC 33656 Site: position = -78 score = 5.15707 sequence = TAGTGAAAATTTTAACAA Gene: EUBREC_1522: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Roseburia intestinalis L1-82 Site: position = -142 score = 5.15484 sequence = TAGTGAAAAATTTAACAA Gene: ROSINTL182_01942: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Ruminococcus gnavus ATCC 29149 Site: position = -97 score = 4.65237 sequence = TTGATGAATCTTTAACAA Gene: RUMGNA_01756: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Ruminococcus lactaris ATCC 29176 Site: position = -96 score = 4.61885 sequence = TTGATGAATTCTTAACAA Gene: RUMLAC_01918: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
pgk	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_01591: Phosphoglycerate kinase (EC 2.7.2.3)	Blautia hansenii DSM 20583 Gene: BLAHAN_03010: Phosphoglycerate kinase (EC 2.7.2.3)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01252: Phosphoglycerate kinase (EC 2.7.2.3)	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100019259: Phosphoglycerate kinase (EC 2.7.2.3)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05215: Phosphoglycerate kinase (EC 2.7.2.3)	Clostridium nexile DSM 1787 Gene: CLONEX_03006: Phosphoglycerate kinase (EC 2.7.2.3)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01405: Phosphoglycerate kinase (EC 2.7.2.3)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01432: Phosphoglycerate kinase (EC 2.7.2.3)	Dorea longicatena DSM 13814 Gene: DORLON_02436: Phosphoglycerate kinase (EC 2.7.2.3)	Eubacterium eligens ATCC 27750 Gene: EUBELI_01189: Phosphoglycerate kinase (EC 2.7.2.3)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1523: Phosphoglycerate kinase (EC 2.7.2.3)	Roseburia intestinalis L1-82 Gene: ROSINTL182_01943: Phosphoglycerate kinase (EC 2.7.2.3)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01757: Phosphoglycerate kinase (EC 2.7.2.3)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_01919: Phosphoglycerate kinase (EC 2.7.2.3)	Phosphoglycerate kinase (EC 2.7.2.3)
tpi	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_01592: Triosephosphate isomerase (EC 5.3.1.1)	Blautia hansenii DSM 20583 Gene: BLAHAN_03009: Triosephosphate isomerase (EC 5.3.1.1)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01253: Triosephosphate isomerase (EC 5.3.1.1)	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100019264: Triosephosphate isomerase (EC 5.3.1.1)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05216: Triosephosphate isomerase (EC 5.3.1.1)	Clostridium nexile DSM 1787 Gene: CLONEX_03005: Triosephosphate isomerase (EC 5.3.1.1)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01406: Triosephosphate isomerase (EC 5.3.1.1)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01433: Triosephosphate isomerase (EC 5.3.1.1)	Dorea longicatena DSM 13814 Gene: DORLON_02435: Triosephosphate isomerase (EC 5.3.1.1)	* Eubacterium eligens ATCC 27750 Site: position = -144 score = 5.26629 sequence = TTGTTATTTATTTCACAA Gene: EUBELI_01188: Triosephosphate isomerase (EC 5.3.1.1)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1524: Triosephosphate isomerase (EC 5.3.1.1)	Roseburia intestinalis L1-82 Gene: ROSINTL182_01944: Triosephosphate isomerase (EC 5.3.1.1)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01758: Triosephosphate isomerase (EC 5.3.1.1)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_01920: Triosephosphate isomerase (EC 5.3.1.1)	Triosephosphate isomerase (EC 5.3.1.1)
pgm	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_01593: Phosphoglycerate mutase (EC 5.4.2.1)	Blautia hansenii DSM 20583 Gene: BLAHAN_03003: Phosphoglycerate mutase (EC 5.4.2.1)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_04617: Phosphoglycerate mutase (EC 5.4.2.1)	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100019269: Phosphoglycerate mutase (EC 5.4.2.1)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05217: Phosphoglycerate mutase (EC 5.4.2.1)	Clostridium nexile DSM 1787 Gene: CLONEX_03003: Phosphoglycerate mutase (EC 5.4.2.1)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01408: Phosphoglycerate mutase (EC 5.4.2.1)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01435: Phosphoglycerate mutase (EC 5.4.2.1)	Dorea longicatena DSM 13814 Gene: DORLON_02434: Phosphoglycerate mutase (EC 5.4.2.1)	Eubacterium eligens ATCC 27750 Gene: EUBELI_01187: Phosphoglycerate mutase (EC 5.4.2.1)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1525: Phosphoglycerate mutase (EC 5.4.2.1)	Roseburia intestinalis L1-82 Gene: ROSINTL182_01881: Phosphoglycerate mutase (EC 5.4.2.1)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01941: Phosphoglycerate mutase (EC 5.4.2.1)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_01928: Phosphoglycerate mutase (EC 5.4.2.1)	Phosphoglycerate mutase (EC 5.4.2.1)

CRON 10.
bdh	* Bacteroides pectinophilus ATCC 43243 Site: position = -43 score = 5.14125 sequence = ATGATAAAAAATTAACGA Gene: BACPEC_03060: Butanol dehydrogenase; Butyraldehyde dehydrogenase	* Blautia hansenii DSM 20583 Site: position = -65 score = 4.84279 sequence = TCGTTAAAAAAATAACGT Site: position = -51 score = 5.0083 sequence = ACGTTAAAAAAATAACAT Gene: BLAHAN_03194: Butanol dehydrogenase; Butyraldehyde dehydrogenase	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -54 score = 5.18004 sequence = TTGTTAAAGAAATAACAA Gene: Cbac1_010100015703: Butanol dehydrogenase; Butyraldehyde dehydrogenase	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01144: Butanol dehydrogenase; Butyraldehyde dehydrogenase	* Clostridium nexile DSM 1787 Site: position = -71 score = 4.63422 sequence = GCGTTAAATAATTAACAG Site: position = -43 score = 4.5185 sequence = CTGTTAAAAGGTTAACAA Gene: CLONEX_01601: Butanol dehydrogenase; Butyraldehyde dehydrogenase	Clostridium scindens ATCC 35704	* Dorea formicigenerans ATCC 27755 Site: position = -76 score = 4.88058 sequence = GCGTTAAATTATTATCAA Site: position = -43 score = 4.53452 sequence = GTGATAAAAATTTAACGC Gene: DORFOR_01493: Butanol dehydrogenase; Butyraldehyde dehydrogenase	* Dorea longicatena DSM 13814 Site: position = -110 score = 4.52315 sequence = ATATTAAAAAAATCACAA Site: position = -44 score = 4.5327 sequence = GTGTTAAAAGATTAACAC Gene: DORLON_00585: Butanol dehydrogenase; Butyraldehyde dehydrogenase	* Eubacterium eligens ATCC 27750 Site: position = -28 score = 5.40832 sequence = TTGTTTATAATTTAACAA Gene: EUBELI_02006: Butanol dehydrogenase; Butyraldehyde dehydrogenase	Eubacterium rectale ATCC 33656 Gene: EUBREC_2225: Butanol dehydrogenase; Butyraldehyde dehydrogenase	* Roseburia intestinalis L1-82 Site: position = -125 score = 5.58132 sequence = TTGTTATTTAATTAACAA Gene: ROSINTL182_03172: Butanol dehydrogenase; Butyraldehyde dehydrogenase	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_00563: Butanol dehydrogenase; Butyraldehyde dehydrogenase	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_02095: Butanol dehydrogenase; Butyraldehyde dehydrogenase	Butanol dehydrogenase; Butyraldehyde dehydrogenase

CRON 11.
adhE	* Bacteroides pectinophilus ATCC 43243 Site: position = -48 score = 5.48434 sequence = TTGTTAAAATATTAACGA Gene: BACPEC_02251: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -92 score = 4.86975 sequence = TTGACATATTTTTAACGA Site: position = -50 score = 5.55211 sequence = TTGTTAATTAATTATCAA Gene: Cbac1_010100020622: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Clostridium bolteae ATCC BAA-613 Site: position = -135 score = 4.79299 sequence = TTGACATTTTTTTAACGA Site: position = -93 score = 5.55211 sequence = TTGTTAATTAATTATCAA Gene: CLOBOL_06541: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Clostridium nexile DSM 1787 Site: position = -73 score = 5.01701 sequence = TTGACAAATATTTAACGA Gene: CLONEX_04092: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Clostridium scindens ATCC 35704 Site: position = -54 score = 5.48162 sequence = TTGTTAAAAAAATATCAA Site: position = -29 score = 5.26793 sequence = TTGACAAATAATTAACAA Gene: CLOSCI_02188: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Dorea formicigenerans ATCC 27755 Site: position = -150 score = 5.06746 sequence = ATGATAAAAAATAAACAA Site: position = -130 score = 5.15729 sequence = ATGTTAAAAAAATATCAT Site: position = -105 score = 4.94025 sequence = TTGACAAATAATTAACGA Gene: DORFOR_01318: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Dorea longicatena DSM 13814 Site: position = -117 score = 5.31945 sequence = ATGTTAAAAAAATATCAA Site: position = -97 score = 4.92766 sequence = ATGTGAAAAAAATATCAA Site: position = -72 score = 4.78988 sequence = TTGACAAAGAATTAACAA Gene: DORLON_02221: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Eubacterium eligens ATCC 27750 Site: position = -54 score = 5.6311 sequence = TTGTTAAATTATTATCAA Gene: EUBELI_02054: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	* Ruminococcus gnavus ATCC 29149 Site: position = -116 score = 4.57128 sequence = ATGTTAAAAAGATAACGT Site: position = -102 score = 4.85485 sequence = ACGTTAAATATTTGTCAA Site: position = -76 score = 5.26793 sequence = TTGACAATTATTTAACAA Gene: RUMGNA_02651: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Ruminococcus lactaris ATCC 29176 Site: position = -63 score = 5.38696 sequence = GTGTTAAATTATTAACAA Site: position = -37 score = 4.86571 sequence = TTGACAATTTATTAACGA Gene: RUMLAC_02580: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
stpK	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_02252: Mn2+-dependent serine/threonine protein kinase	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -119 score = 5.21801 sequence = ACGTTAAAAATTTATCAA Gene: Cbac1_010100013906: Mn2+-dependent serine/threonine protein kinase	* Clostridium bolteae ATCC BAA-613 Site: position = -119 score = 5.21801 sequence = ACGTTAAAAATTTATCAA Gene: CLOBOL_00811: Mn2+-dependent serine/threonine protein kinase	* Clostridium nexile DSM 1787 Site: position = -102 score = 4.83783 sequence = TTGTTAAAAAATACTCAA Gene: CLONEX_04091: Mn2+-dependent serine/threonine protein kinase	* Clostridium scindens ATCC 35704 Site: position = -107 score = 5.57269 sequence = ATGTTAAATATATAACAA Site: position = -69 score = 4.97953 sequence = AAGTTAAAAAAATATCAA Gene: CLOSCI_02187: Mn2+-dependent serine/threonine protein kinase	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01317: Mn2+-dependent serine/threonine protein kinase	* Dorea longicatena DSM 13814 Site: position = -144 score = 5.49815 sequence = ATGTTAAAAAAATAACAA Site: position = -106 score = 4.7499 sequence = TAGTGAAAAAAATATCAA Gene: DORLON_02222: Mn2+-dependent serine/threonine protein kinase	Eubacterium eligens ATCC 27750 Gene: EUBELI_02055: Mn2+-dependent serine/threonine protein kinase	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	* Ruminococcus gnavus ATCC 29149 Site: position = -181 score = 4.79392 sequence = AAGTTAAGAAATTAACAA Gene: RUMGNA_02650: Mn2+-dependent serine/threonine protein kinase	* Ruminococcus lactaris ATCC 29176 Site: position = -157 score = 5.49815 sequence = ATGTTAAAAAAATAACAA Gene: RUMLAC_02581: Mn2+-dependent serine/threonine protein kinase	Mn2+-dependent serine/threonine protein kinase

CRON 12.
COG183	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	* Eubacterium rectale ATCC 33656 Site: position = -111 score = 5.27015 sequence = TTGACAAATTATTAACAA Site: position = -54 score = 5.38696 sequence = TTGTTAAAAAATTAACAG Gene: EUBREC_0733: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Roseburia intestinalis L1-82 Site: position = -82 score = 5.38696 sequence = TTGTTAAAAAATTAACAG Gene: ROSINTL182_02619: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	3-ketoacyl-CoA thiolase (EC 2.3.1.16)

CRON 13.
COG1959	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583 Gene: BLAHAN_03210: Predicted transcriptional regulator, Rrf2 family	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -34 score = 5.2568 sequence = TTGTTATATCTTTAACAA Gene: Cbac1_010100004767: Predicted transcriptional regulator, Rrf2 family	* Clostridium bolteae ATCC BAA-613 Site: position = -33 score = 5.3506 sequence = TTGTTACAATTTTAACAA Gene: CLOBOL_02457: Predicted transcriptional regulator, Rrf2 family	Clostridium nexile DSM 1787 Gene: CLONEX_02580: Predicted transcriptional regulator, Rrf2 family	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01768: Predicted transcriptional regulator, Rrf2 family	Ruminococcus lactaris ATCC 29176	Predicted transcriptional regulator, Rrf2 family

CRON 14.
asrA	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -134 score = 4.62163 sequence = ATGATAAATTTTTATTAT Site: position = -76 score = 5.3509 sequence = TTGTTATAATAATAACAT Gene: Cbac1_010100025357: anaerobic sulfite reductase, A subunit	* Clostridium bolteae ATCC BAA-613 Site: position = -133 score = 4.62163 sequence = ATGATAAAAATTTATTAT Site: position = -75 score = 5.3509 sequence = TTGTTATAATAATAACAT Gene: CLOBOL_00463: anaerobic sulfite reductase, A subunit	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	anaerobic sulfite reductase, A subunit
asrB	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100025362: anaerobic sulfite reductase subunit B	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_00462: anaerobic sulfite reductase subunit B	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	anaerobic sulfite reductase subunit B
asrC	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100025367: anaerobic sulfite reductase subunit C	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_00461: anaerobic sulfite reductase subunit C	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	anaerobic sulfite reductase subunit C

CRON 15.
pfkA	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_03023: 6-phosphofructokinase (EC 2.7.1.11)	Blautia hansenii DSM 20583 Gene: BLAHAN_00119: 6-phosphofructokinase (EC 2.7.1.11)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_03235: 6-phosphofructokinase (EC 2.7.1.11)	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100001775: 6-phosphofructokinase (EC 2.7.1.11)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_04803: 6-phosphofructokinase (EC 2.7.1.11)	Clostridium nexile DSM 1787 Gene: CLONEX_02545: 6-phosphofructokinase (EC 2.7.1.11)	Clostridium scindens ATCC 35704 Gene: CLOSCI_03116: 6-phosphofructokinase (EC 2.7.1.11)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01824: 6-phosphofructokinase (EC 2.7.1.11)	Dorea longicatena DSM 13814 Gene: DORLON_01273: 6-phosphofructokinase (EC 2.7.1.11)	* Eubacterium eligens ATCC 27750 Site: position = -93 score = 5.08559 sequence = TTGGTAAAAAATTATCAA Gene: EUBELI_01680: 6-phosphofructokinase (EC 2.7.1.11)	* Eubacterium rectale ATCC 33656 Site: position = -18 score = 5.30677 sequence = ATGATAATTTTTTAACAT Gene: EUBREC_1058: 6-phosphofructokinase (EC 2.7.1.11)	Roseburia intestinalis L1-82 Gene: ROSINTL182_02777: 6-phosphofructokinase (EC 2.7.1.11)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01346: 6-phosphofructokinase (EC 2.7.1.11)	2 Ruminococcus lactaris ATCC 29176* Site: position = -61 score = 4.86868 sequence = TTGATAAAAAATAGACAA Gene: RUMLAC_02728: 6-phosphofructokinase (EC 2.7.1.11) Gene: RUMLAC_00699: 6-phosphofructokinase (EC 2.7.1.11)	6-phosphofructokinase (EC 2.7.1.11)

CRON 16.
pflB	* Bacteroides pectinophilus ATCC 43243 Site: position = -128 score = 5.23458 sequence = TTGTTGATTTTTTAACAA Gene: BACPEC_03240: Pyruvate formate-lyase (EC 2.3.1.54)	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704 Gene: CLOSCI_00725: Pyruvate formate-lyase (EC 2.3.1.54)	* Dorea formicigenerans ATCC 27755 Site: position = -160 score = 5.01742 sequence = TTGTCAATAGTTTAACAA Gene: DORFOR_01508: Pyruvate formate-lyase (EC 2.3.1.54)	Dorea longicatena DSM 13814 Gene: DORLON_00721: Pyruvate formate-lyase (EC 2.3.1.54)	Eubacterium eligens ATCC 27750 Gene: EUBELI_20055: Pyruvate formate-lyase (EC 2.3.1.54)	Eubacterium rectale ATCC 33656 Gene: EUBREC_0469: Pyruvate formate-lyase (EC 2.3.1.54)	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_02002: Pyruvate formate-lyase (EC 2.3.1.54)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_02815: Pyruvate formate-lyase (EC 2.3.1.54)	Pyruvate formate-lyase (EC 2.3.1.54)

CRON 17.
cat2	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	* Eubacterium rectale ATCC 33656 Site: position = -60 score = 5.17047 sequence = TTGTTATTTTTTTAACGT Gene: EUBREC_3075: 4-hydroxybutyrate:acetyl-CoA CoA transferase (EC 2.3.1.-)	* Roseburia intestinalis L1-82 Site: position = -30 score = 5.17889 sequence = ATGGTAAATTTTTAACAA Gene: ROSINTL182_02872: 4-hydroxybutyrate:acetyl-CoA CoA transferase (EC 2.3.1.-)	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	4-hydroxybutyrate:acetyl-CoA CoA transferase (EC 2.3.1.-)

CRON 18.
crt	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	* Eubacterium rectale ATCC 33656 Site: position = -91 score = 4.80728 sequence = TTGACAAAAATTTGTCAA Gene: EUBREC_1017: 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55)	* Roseburia intestinalis L1-82 Site: position = -41 score = 5.6311 sequence = TTGTTAATTTTTTATCAA Gene: ROSINTL182_00883: 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55)	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55)

CRON 19.
nadA	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583 Gene: BLAHAN_02639: Quinolinate synthetase (EC 4.1.99.-)	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03914: Quinolinate synthetase (EC 4.1.99.-)	Clostridium nexile DSM 1787 Gene: CLONEX_03264: Quinolinate synthetase (EC 4.1.99.-)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01553: Quinolinate synthetase (EC 4.1.99.-)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01504: Quinolinate synthetase (EC 4.1.99.-)	Dorea longicatena DSM 13814 Gene: DORLON_00278: Quinolinate synthetase (EC 4.1.99.-)	Eubacterium eligens ATCC 27750 Gene: EUBELI_01431: Quinolinate synthetase (EC 4.1.99.-)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1033: Quinolinate synthetase (EC 4.1.99.-)	Roseburia intestinalis L1-82 Gene: ROSINTL182_03918: Quinolinate synthetase (EC 4.1.99.-)	* Ruminococcus gnavus ATCC 29149 Site: position = -43 score = 5.21801 sequence = ACGATAAAAATTTAACAA Gene: RUMGNA_03804: Quinolinate synthetase (EC 4.1.99.-)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00642: Quinolinate synthetase (EC 4.1.99.-)	Quinolinate synthetase (EC 4.1.99.-)
nadB	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583 Gene: BLAHAN_02638: L-aspartate oxidase (EC 1.4.3.16)	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03915: L-aspartate oxidase (EC 1.4.3.16)	Clostridium nexile DSM 1787 Gene: CLONEX_03263: L-aspartate oxidase (EC 1.4.3.16)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01552: L-aspartate oxidase (EC 1.4.3.16)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01505: L-aspartate oxidase (EC 1.4.3.16)	Dorea longicatena DSM 13814 Gene: DORLON_01089: L-aspartate oxidase (EC 1.4.3.16)	Eubacterium eligens ATCC 27750 Gene: EUBELI_01430: L-aspartate oxidase (EC 1.4.3.16)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1034: L-aspartate oxidase (EC 1.4.3.16)	Roseburia intestinalis L1-82 Gene: ROSINTL182_03919: L-aspartate oxidase (EC 1.4.3.16)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_03805: L-aspartate oxidase (EC 1.4.3.16)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00641: L-aspartate oxidase (EC 1.4.3.16)	L-aspartate oxidase (EC 1.4.3.16)
nadC	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583 Gene: BLAHAN_02635: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03916: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Clostridium nexile DSM 1787 Gene: CLONEX_03262: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01551: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01506: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Dorea longicatena DSM 13814 Gene: DORLON_01088: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Eubacterium eligens ATCC 27750 Gene: EUBELI_01429: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1035: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Roseburia intestinalis L1-82 Gene: ROSINTL182_03920: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_03806: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00640: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)	Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
niaR	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_00422: NAD biosynthesis transcription regulator, HTH_11 family	Blautia hansenii DSM 20583 Gene: BLAHAN_02634: NAD biosynthesis transcription regulator, HTH_11 family	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100010440: NAD biosynthesis transcription regulator, HTH_11 family	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03917: NAD biosynthesis transcription regulator, HTH_11 family	Clostridium nexile DSM 1787 Gene: CLONEX_03261: NAD biosynthesis transcription regulator, HTH_11 family	Clostridium scindens ATCC 35704 Gene: CLOSCI_01550: NAD biosynthesis transcription regulator, HTH_11 family	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814 Gene: DORLON_01087: NAD biosynthesis transcription regulator, HTH_11 family	Eubacterium eligens ATCC 27750 Gene: EUBELI_01428: NAD biosynthesis transcription regulator, HTH_11 family	Eubacterium rectale ATCC 33656 Gene: EUBREC_1036: NAD biosynthesis transcription regulator, HTH_11 family	Roseburia intestinalis L1-82 Gene: ROSINTL182_03921: NAD biosynthesis transcription regulator, HTH_11 family	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_03807: NAD biosynthesis transcription regulator, HTH_11 family	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00639: NAD biosynthesis transcription regulator, HTH_11 family	NAD biosynthesis transcription regulator, HTH_11 family

CRON 20.
rex	* Bacteroides pectinophilus ATCC 43243 Site: position = -69 score = 4.35819 sequence = TTGACATGATTTTAACGA Site: position = 7 score = 4.39024 sequence = GCGATAAAAAAATATCAT Gene: BACPEC_01011: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	* Blautia hansenii DSM 20583 Site: position = -40 score = 4.7192 sequence = TTGACTTTAATTTAACAA Gene: BLAHAN_02340: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	* Bryantella formatexigens DSM 14469 Site: position = -59 score = 4.56671 sequence = TTGACATTTTTTTCACAT Gene: BRYFOR_02286: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	* Clostridiales bacterium 1_7_47_FAA Site: position = -77 score = 4.3369 sequence = TTGACATTTTTTTGACAC Gene: Cbac1_010100026274: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	* Clostridium bolteae ATCC BAA-613 Site: position = -79 score = 4.26988 sequence = TTGACATTTTTTTGACGT Gene: CLOBOL_04148: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	Clostridium nexile DSM 1787 Gene: CLONEX_01590: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00613: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_01483: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	Dorea longicatena DSM 13814 Gene: DORLON_00639: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	* Eubacterium eligens ATCC 27750 Site: position = -114 score = 4.80784 sequence = TGGTTAAAATTTTGACAT Gene: EUBELI_01381: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	* Eubacterium rectale ATCC 33656 Site: position = -225 score = 4.78777 sequence = ATGTTAAATTCTTAACAC Gene: EUBREC_1967: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	* Roseburia intestinalis L1-82 Site: position = -69 score = 4.73201 sequence = TAGTTAAAAATTTCACAC Gene: ROSINTL182_04859: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_00579: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_02084: Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)	Redox-sensitive transcriptional regulator (AT-rich DNA-binding protein)

CRON 21.
por	* Bacteroides pectinophilus ATCC 43243 Site: position = -158 score = 4.43521 sequence = TTGACAAAGGTTTAACAA Gene: BACPEC_01494: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Blautia hansenii DSM 20583 Gene: BLAHAN_03209: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01924: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	2 Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100006533: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-) Gene: Cbac1_010100001915: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01920: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Clostridium nexile DSM 1787 Gene: CLONEX_03662: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01585: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	* Dorea formicigenerans ATCC 27755 Site: position = -133 score = 4.76523 sequence = TCGTTAATTTTGTATCAA Gene: DORFOR_02415: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Dorea longicatena DSM 13814 Gene: DORLON_01144: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Eubacterium eligens ATCC 27750 Gene: EUBELI_00741: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Eubacterium rectale ATCC 33656 Gene: EUBREC_1472: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Roseburia intestinalis L1-82 Gene: ROSINTL182_01855: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_03464: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	* Ruminococcus lactaris ATCC 29176 Site: position = -179 score = 5.07714 sequence = TTGTGAAAAAATTATCAT Gene: RUMLAC_01487: Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)	Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)

CRON 22.
nadO	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -67 score = 5.29378 sequence = TTGTTAATTAGTTAACAA Gene: Cbac1_010100004252: NADH oxidase	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	NADH oxidase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Rex - Clostridia-3

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --