Regulog Cobalamin - Pseudomonadaceae

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Phylum:	Proteobacteria

Member of regulog collections

By taxonomy - Pseudomonadaceae
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Pseudomonas aeruginosa PAO1	24	5
Pseudomonas entomophila L48	23	6
Pseudomonas putida KT2440	18	4
Pseudomonas syringae pv. tomato str. DC3000	19	4
Pseudomonas fluorescens Pf-5	22	5
Pseudomonas mendocina ymp	25	6
Pseudomonas stutzeri A1501	14	2
Azotobacter vinelandii AvOP	11	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
btuB	* Pseudomonas aeruginosa PAO1 Site: position = -303 score = 112.86 sequence = CCATCCGGCCCGTTC... Gene: PA2911: Outer membrane vitamin B12 receptor BtuB	* Pseudomonas entomophila L48 Site: position = -315 score = 116.97 sequence = CAGATGCGCGCCAGT... Gene: PSEEN2012: Outer membrane vitamin B12 receptor BtuB	* Pseudomonas putida KT2440 Site: position = -258 score = 119.18 sequence = CAGATGCGCGCCAGT... Gene: PP2420: Outer membrane vitamin B12 receptor BtuB	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO5560: Outer membrane vitamin B12 receptor BtuB	2 Pseudomonas fluorescens Pf-5* Site: position = -154 score = 123.03 sequence = CATATGCGCGCCAGT... Gene: PFL_2970: Outer membrane vitamin B12 receptor BtuB Gene: PFL_0646: Outer membrane vitamin B12 receptor BtuB	* Pseudomonas mendocina ymp Site: position = -394 score = 118.91 sequence = TCATATCCGCCCCGC... Gene: Pmen_4567: Outer membrane vitamin B12 receptor BtuB	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Outer membrane vitamin B12 receptor BtuB
btuD	Pseudomonas aeruginosa PAO1 Gene: PA2912: Vitamin B12 ABC transporter, ATPase component BtuD	* Pseudomonas entomophila L48 Site: position = -314 score = 109.02 sequence = ATGCGCCCCTTGTTT... Gene: PSEEN3066: Vitamin B12 ABC transporter, ATPase component BtuD	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO5561: Vitamin B12 ABC transporter, ATPase component BtuD	Pseudomonas fluorescens Pf-5 Gene: PFL_0645: Vitamin B12 ABC transporter, ATPase component BtuD	Pseudomonas mendocina ymp Gene: Pmen_4566: Vitamin B12 ABC transporter, ATPase component BtuD	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Vitamin B12 ABC transporter, ATPase component BtuD
btuF	Pseudomonas aeruginosa PAO1 Gene: PA2913: Vitamin B12 ABC transporter, B12-binding component BtuF	Pseudomonas entomophila L48 Gene: PSEEN3067: Vitamin B12 ABC transporter, B12-binding component BtuF	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO5562: Vitamin B12 ABC transporter, B12-binding component BtuF	Pseudomonas fluorescens Pf-5 Gene: PFL_0644: Vitamin B12 ABC transporter, B12-binding component BtuF	Pseudomonas mendocina ymp Gene: Pmen_4565: Vitamin B12 ABC transporter, B12-binding component BtuF	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC	Pseudomonas aeruginosa PAO1 Gene: PA2914: Vitamin B12 ABC transporter, permease component BtuC	Pseudomonas entomophila L48 Gene: PSEEN3068: Vitamin B12 ABC transporter, permease component BtuC	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO5563: Vitamin B12 ABC transporter, permease component BtuC	Pseudomonas fluorescens Pf-5 Gene: PFL_0643: Vitamin B12 ABC transporter, permease component BtuC	Pseudomonas mendocina ymp Gene: Pmen_4564: Vitamin B12 ABC transporter, permease component BtuC	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Vitamin B12 ABC transporter, permease component BtuC

CRON 2.
cbtC	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	* Pseudomonas mendocina ymp Site: position = -258 score = 125.14 sequence = GAGTAAGGTTGCCGC... Gene: Pmen_3752: Predicted cobalt transporter CbtC	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Predicted cobalt transporter CbtC

CRON 3.
btuB1	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48 Gene: PSEEN0599: Outer membrane vitamin B12 receptor BtuB	Pseudomonas putida KT2440 Gene: PP0525: Outer membrane vitamin B12 receptor BtuB	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5 Gene: PFL_5511: Outer membrane vitamin B12 receptor BtuB	* Pseudomonas mendocina ymp Site: position = -290 score = 82.64 sequence = CATTCATGTTCCGCC... Gene: Pmen_3845: Outer membrane vitamin B12 receptor BtuB	* Pseudomonas stutzeri A1501 Site: position = -314 score = 98.51 sequence = GCGTTTTCTTATCCG... Gene: PST_0846: Outer membrane vitamin B12 receptor BtuB	Azotobacter vinelandii AvOP Gene: Avin_07860: Outer membrane vitamin B12 receptor BtuB	Outer membrane vitamin B12 receptor BtuB

CRON 4.
btuB2	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	* Pseudomonas fluorescens Pf-5 Site: position = -189 score = 126.24 sequence = CATATGCCGCCCAGT... Gene: PFL_2240: Outer membrane vitamin B12 receptor BtuB	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Outer membrane vitamin B12 receptor BtuB
cbiW	Pseudomonas aeruginosa PAO1	* Pseudomonas entomophila L48 Site: position = -297 score = 103.97 sequence = CATGCCGCCCAGTTT... Gene: PSEEN2578: Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5 Gene: PFL_2239: Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
btuF2	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5 Gene: PFL_2238: Vitamin B12 ABC transporter, B12-binding component BtuF	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Vitamin B12 ABC transporter, B12-binding component BtuF

CRON 5.
btuF	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	* Pseudomonas putida KT2440 Site: position = -226 score = 102.77 sequence = GTCTACCATGCGGGC... Gene: PP2418: Vitamin B12 ABC transporter, B12-binding component BtuF	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = -159 score = 123.58 sequence = TTACCATGCCGGCCG... Gene: PSPTO3256: Vitamin B12 ABC transporter, B12-binding component BtuF	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440 Gene: PP2417: Vitamin B12 ABC transporter, permease component BtuC	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO3257: Vitamin B12 ABC transporter, permease component BtuC	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Vitamin B12 ABC transporter, permease component BtuC
btuD	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440 Gene: PP2416: Vitamin B12 ABC transporter, ATPase component BtuD	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO3258: Vitamin B12 ABC transporter, ATPase component BtuD	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Vitamin B12 ABC transporter, ATPase component BtuD

CRON 6.
btuB2	* Pseudomonas aeruginosa PAO1 Site: position = -303 score = 82.28 sequence = CTGCGCGCCTTGCGA... Gene: PA1271: Outer membrane vitamin B12 receptor BtuB	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	* Pseudomonas stutzeri A1501 Site: position = -373 score = 105.73 sequence = ACCTCCGCGTCGCCT... Gene: PST_1289: Outer membrane vitamin B12 receptor BtuB	* Azotobacter vinelandii AvOP Site: position = -310 score = 91.29 sequence = CCCTGCGCGCCTCGC... Gene: Avin_33130: Outer membrane vitamin B12 receptor BtuB / Optional hypothetical component of the B12 transporter BtuM / Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Outer membrane vitamin B12 receptor BtuB
btuM	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501 Gene: PST_1290: Optional hypothetical component of the B12 transporter BtuM	Azotobacter vinelandii AvOP	Optional hypothetical component of the B12 transporter BtuM
btuR	Pseudomonas aeruginosa PAO1 Gene: PA1272: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Pseudomonas entomophila L48 Site: position = -330 score = 96.17 sequence = CTTCGCGGCGTGTTT... Gene: PSEEN1378: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Pseudomonas putida KT2440 Site: position = -340 score = 87.42 sequence = CTTCGCGGCGTGTTT... Gene: PP1672: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = -304 score = 113.92 sequence = CTTCGCGGCTTGTTT... Gene: PSPTO1708: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Pseudomonas fluorescens Pf-5 Site: position = -315 score = 105.58 sequence = ACCTTCGCGACTTGT... Gene: PFL_4431: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Pseudomonas mendocina ymp Site: position = -394 score = 97.27 sequence = CTGCGCGCCTTGCTT... Gene: Pmen_1750: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Pseudomonas stutzeri A1501 Gene: PST_1291: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Azotobacter vinelandii AvOP	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cbiA	Pseudomonas aeruginosa PAO1 Gene: PA1273: Cobyrinic acid A,C-diamide synthase	Pseudomonas entomophila L48 Gene: PSEEN1379: Cobyrinic acid A,C-diamide synthase	Pseudomonas putida KT2440 Gene: PP1673: Cobyrinic acid A,C-diamide synthase	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1709: Cobyrinic acid A,C-diamide synthase	Pseudomonas fluorescens Pf-5 Gene: PFL_4430: Cobyrinic acid A,C-diamide synthase	Pseudomonas mendocina ymp Gene: Pmen_1751: Cobyrinic acid A,C-diamide synthase	Pseudomonas stutzeri A1501 Gene: PST_1292: Cobyrinic acid A,C-diamide synthase	Azotobacter vinelandii AvOP Gene: Avin_33120: Cobyrinic acid A,C-diamide synthase	Cobyrinic acid A,C-diamide synthase
bluB	Pseudomonas aeruginosa PAO1 Gene: PA1274: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family	Pseudomonas entomophila L48 Gene: PSEEN1380: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family	Pseudomonas putida KT2440 Gene: PP1674: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1710: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family	Pseudomonas fluorescens Pf-5 Gene: PFL_4429: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family	Pseudomonas mendocina ymp Gene: Pmen_1752: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family	Pseudomonas stutzeri A1501 Gene: PST_1293: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family	Azotobacter vinelandii AvOP Gene: Avin_33110: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family	Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
btuF	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501 Gene: PST_1294: Vitamin B12 ABC transporter, B12-binding component BtuF	Azotobacter vinelandii AvOP	Vitamin B12 ABC transporter, B12-binding component BtuF
cbiB	Pseudomonas aeruginosa PAO1 Gene: PA1275: Adenosylcobinamide-phosphate synthase	Pseudomonas entomophila L48 Gene: PSEEN1381: Adenosylcobinamide-phosphate synthase	Pseudomonas putida KT2440 Gene: PP1675: Adenosylcobinamide-phosphate synthase	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1711: Adenosylcobinamide-phosphate synthase	Pseudomonas fluorescens Pf-5 Gene: PFL_4428: Adenosylcobinamide-phosphate synthase	Pseudomonas mendocina ymp Gene: Pmen_1753: Adenosylcobinamide-phosphate synthase	Pseudomonas stutzeri A1501 Gene: PST_1295: Adenosylcobinamide-phosphate synthase	Azotobacter vinelandii AvOP Gene: Avin_33100: Adenosylcobinamide-phosphate synthase	Adenosylcobinamide-phosphate synthase
cobD	Pseudomonas aeruginosa PAO1 Gene: PA1276: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Pseudomonas entomophila L48 Gene: PSEEN1382: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Pseudomonas putida KT2440 Gene: PP1676: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1712: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Pseudomonas fluorescens Pf-5 Gene: PFL_4427: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Pseudomonas mendocina ymp Gene: Pmen_1754: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Pseudomonas stutzeri A1501 Gene: PST_1296: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Azotobacter vinelandii AvOP Gene: Avin_33090: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiP	Pseudomonas aeruginosa PAO1 Gene: PA1277: Cobyric acid synthase	Pseudomonas entomophila L48 Gene: PSEEN1383: Cobyric acid synthase	Pseudomonas putida KT2440 Gene: PP1677: Cobyric acid synthase	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1713: Cobyric acid synthase	Pseudomonas fluorescens Pf-5 Gene: PFL_4426: Cobyric acid synthase	Pseudomonas mendocina ymp Gene: Pmen_1755: Cobyric acid synthase	Pseudomonas stutzeri A1501 Gene: PST_1297: Cobyric acid synthase	Azotobacter vinelandii AvOP Gene: Avin_33080: Cobyric acid synthase	Cobyric acid synthase
cobU	Pseudomonas aeruginosa PAO1 Gene: PA1278: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Pseudomonas entomophila L48 Gene: PSEEN1384: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Pseudomonas putida KT2440 Gene: PP1678: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1714: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Pseudomonas fluorescens Pf-5 Gene: PFL_4425: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Pseudomonas mendocina ymp Gene: Pmen_1756: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Pseudomonas stutzeri A1501 Gene: PST_1298: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Azotobacter vinelandii AvOP Gene: Avin_33060: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobT	Pseudomonas aeruginosa PAO1 Gene: PA1279: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Pseudomonas entomophila L48 Gene: PSEEN1385: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Pseudomonas putida KT2440 Gene: PP1679: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1715: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Pseudomonas fluorescens Pf-5 Gene: PFL_4424: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Pseudomonas mendocina ymp Gene: Pmen_1757: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Pseudomonas stutzeri A1501 Gene: PST_1299: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Azotobacter vinelandii AvOP Gene: Avin_33050: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cobC	Pseudomonas aeruginosa PAO1 Gene: PA1280: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Pseudomonas entomophila L48 Gene: PSEEN1386: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Pseudomonas putida KT2440 Gene: PP1680: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1716: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Pseudomonas fluorescens Pf-5 Gene: PFL_4423: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Pseudomonas mendocina ymp Gene: Pmen_1758: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Pseudomonas stutzeri A1501 Gene: PST_1300: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Azotobacter vinelandii AvOP Gene: Avin_33040: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cobS	Pseudomonas aeruginosa PAO1 Gene: PA1281: Cobalamin synthase	Pseudomonas entomophila L48 Gene: PSEEN1387: Cobalamin synthase	Pseudomonas putida KT2440 Gene: PP1681: Cobalamin synthase	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO1717: Cobalamin synthase	Pseudomonas fluorescens Pf-5 Gene: PFL_4422: Cobalamin synthase	Pseudomonas mendocina ymp Gene: Pmen_1759: Cobalamin synthase	Pseudomonas stutzeri A1501 Gene: PST_1301: Cobalamin synthase	Azotobacter vinelandii AvOP Gene: Avin_33030: Cobalamin synthase	Cobalamin synthase
Avin_33070	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP Gene: Avin_33070: hypothetical protein	hypothetical protein

CRON 7.
cobW	* Pseudomonas aeruginosa PAO1 Site: position = -238 score = 104.56 sequence = CGTAGCCTTGCCGGT... Gene: PA2945: CobW GTPase involved in cobalt insertion for B12 biosynthesis	* Pseudomonas entomophila L48 Site: position = -299 score = 97.48 sequence = TAGCCTTGCCGCTTC... Gene: PSEEN2432: CobW GTPase involved in cobalt insertion for B12 biosynthesis	* Pseudomonas putida KT2440 Site: position = -307 score = 100.75 sequence = CGTAGCCTTGCCACT... Gene: PP3508: CobW GTPase involved in cobalt insertion for B12 biosynthesis	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = -339 score = 106.84 sequence = CGTAGCCTTGCCGGT... Gene: PSPTO3150: CobW GTPase involved in cobalt insertion for B12 biosynthesis	* Pseudomonas fluorescens Pf-5 Site: position = -98 score = 94.95 sequence = CGTAGCCTTGCGCTT... Gene: PFL_3655: CobW GTPase involved in cobalt insertion for B12 biosynthesis	* Pseudomonas mendocina ymp Site: position = -291 score = 113.12 sequence = GTAGCCTTCTCGCTT... Gene: Pmen_4587: CobW GTPase involved in cobalt insertion for B12 biosynthesis	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	CobW GTPase involved in cobalt insertion for B12 biosynthesis
cobN	Pseudomonas aeruginosa PAO1 Gene: PA2944: CobN component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas entomophila L48 Gene: PSEEN2433: CobN component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas putida KT2440 Gene: PP3507: CobN component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO3149: CobN component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas fluorescens Pf-5 Gene: PFL_3654: CobN component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas mendocina ymp Gene: Pmen_4586: CobN component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	CobN component of cobalt chelatase involved in B12 biosynthesis
chII	Pseudomonas aeruginosa PAO1 Gene: PA2942: ChlI component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas entomophila L48 Gene: PSEEN2434: ChlI component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas putida KT2440 Gene: PP3506: ChlI component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO3148: ChlI component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas fluorescens Pf-5 Gene: PFL_3653: ChlI component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas mendocina ymp Gene: Pmen_4585: ChlI component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	ChlI component of cobalt chelatase involved in B12 biosynthesis
chlD	Pseudomonas aeruginosa PAO1 Gene: PA2941: ChlD component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas entomophila L48 Gene: PSEEN2435: ChlD component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas putida KT2440 Gene: PP3505: ChlD component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO3147: ChlD component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas fluorescens Pf-5 Gene: PFL_3652: ChlD component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas mendocina ymp Gene: Pmen_4584: ChlD component of cobalt chelatase involved in B12 biosynthesis	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	ChlD component of cobalt chelatase involved in B12 biosynthesis
cbiL	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48 Gene: PSEEN3208: Precorrin-6A synthase (EC 2.1.1.152)	Pseudomonas putida KT2440 Gene: PP3763: Precorrin-6A synthase (EC 2.1.1.152)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO2709: Precorrin-6A synthase (EC 2.1.1.152)	Pseudomonas fluorescens Pf-5 Gene: PFL_2249: Precorrin-6A synthase (EC 2.1.1.152)	Pseudomonas mendocina ymp Gene: Pmen_4583: Precorrin-6A synthase (EC 2.1.1.152)	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Precorrin-6A synthase (EC 2.1.1.152)

CRON 8.
cobG	* Pseudomonas aeruginosa PAO1 Site: position = -252 score = 87.78 sequence = GCATAATAGCGCGTT... Gene: PA2906: Cobalamin biosynthesis protein CobG	Pseudomonas entomophila L48 Gene: PSEEN4871: Cobalamin biosynthesis protein CobG	Pseudomonas putida KT2440 Gene: PP4829: Cobalamin biosynthesis protein CobG	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO4877: Cobalamin biosynthesis protein CobG	Pseudomonas fluorescens Pf-5 Gene: PFL_0657: Cobalamin biosynthesis protein CobG	* Pseudomonas mendocina ymp Site: position = -184 score = 99.84 sequence = GCCTTCGCGGGAGTG... Gene: Pmen_4571: Cobalamin biosynthesis protein CobG	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Cobalamin biosynthesis protein CobG
cbiC	Pseudomonas aeruginosa PAO1 Gene: PA2905: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Pseudomonas entomophila L48 Gene: PSEEN4870: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Pseudomonas putida KT2440 Gene: PP4828: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO4876: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Pseudomonas fluorescens Pf-5 Gene: PFL_0658: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Pseudomonas mendocina ymp Gene: Pmen_4572: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiL	Pseudomonas aeruginosa PAO1 Gene: PA2904: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Pseudomonas entomophila L48 Gene: PSEEN4869: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Pseudomonas putida KT2440 Gene: PP4827: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO4875: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Pseudomonas fluorescens Pf-5 Gene: PFL_0659: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Pseudomonas mendocina ymp Gene: Pmen_4573: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiGH	Pseudomonas aeruginosa PAO1 Gene: PA2903: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Pseudomonas entomophila L48 Gene: PSEEN4868: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Pseudomonas putida KT2440 Gene: PP4826: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO4874: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Pseudomonas fluorescens Pf-5 Gene: PFL_0660: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Pseudomonas mendocina ymp Gene: Pmen_4574: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase

CRON 9.
cbtB	Pseudomonas aeruginosa PAO1	* Pseudomonas entomophila L48 Site: position = -333 score = 102.94 sequence = TGCTAGCGCATTGCG... Gene: PSEEN2431: hypothetical protein	Pseudomonas putida KT2440	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = -309 score = 110.34 sequence = CTGTGCACCTTGTTT... Gene: PSPTO3151: hypothetical protein	* Pseudomonas fluorescens Pf-5 Site: position = -156 score = 105.34 sequence = CTACACACCTTGTTA... Gene: PFL_3656: hypothetical protein	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	hypothetical protein
cbtA	* Pseudomonas aeruginosa PAO1 Site: position = -58 score = 77.81 sequence = CTAGGCGGGTTGTCC... Gene: PA2946: Predicted cobalt transporter CbtA	Pseudomonas entomophila L48 Gene: PSEEN2429: Predicted cobalt transporter CbtA	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO3152: Predicted cobalt transporter CbtA	Pseudomonas fluorescens Pf-5 Gene: PFL_3657: Predicted cobalt transporter CbtA	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Predicted cobalt transporter CbtA
cobE	Pseudomonas aeruginosa PAO1 Gene: PA2947: Cobalamin biosynthesis protein CobE	Pseudomonas entomophila L48 Gene: PSEEN2428: Cobalamin biosynthesis protein CobE	Pseudomonas putida KT2440 Gene: PP3409: Cobalamin biosynthesis protein CobE	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5 Gene: PFL_3658: Cobalamin biosynthesis protein CobE	Pseudomonas mendocina ymp Gene: Pmen_4588: Cobalamin biosynthesis protein CobE	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Cobalamin biosynthesis protein CobE
cbiF	Pseudomonas aeruginosa PAO1 Gene: PA2948: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Pseudomonas entomophila L48 Gene: PSEEN2427: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Pseudomonas putida KT2440 Gene: PP3410: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO3154: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Pseudomonas fluorescens Pf-5 Gene: PFL_3659: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Pseudomonas mendocina ymp Gene: Pmen_4589: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Cobalamin - Pseudomonadaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --