Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Pseudomonas fluorescens Pf-5

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Pseudomonadaceae
Under regulation:
- Genes 22
- Operons 5
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -154
Score: 123
Sequence: CATATGCGCGCCAGT...
Locus tag: PFL_2970
Name: btuB
Funciton: Outer membrane vitamin B12 receptor BtuB
btuB
Outer membrane vitamin B12 receptor BtuB

Position: -98
Score: 94.9
Sequence: CGTAGCCTTGCGCTT...
Locus tag: PFL_3655
Name: null
Funciton: CobW GTPase involved in cobalt insertion for B12 biosynthesis
Locus tag: PFL_3654
Name: null
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: PFL_3653
Name: chII
Funciton: ChlI component of cobalt chelatase involved in B12 biosynthesis
Locus tag: PFL_3652
Name: chlD
Funciton: ChlD component of cobalt chelatase involved in B12 biosynthesis
CobW GTPase involved in cobalt insertion for B12 biosynthesis
CobN component of cobalt chelatase involved in B12 biosynthesis
chII
ChlI component of cobalt chelatase involved in B12 biosynthesis
chlD
ChlD component of cobalt chelatase involved in B12 biosynthesis

Position: -189
Score: 126.2
Sequence: CATATGCCGCCCAGT...
Locus tag: PFL_2240
Name: btuB2
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: PFL_2239
Name: cbiW
Funciton: Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: PFL_2238
Name: btuF2
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
btuB2
Outer membrane vitamin B12 receptor BtuB
cbiW
Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
btuF2
Vitamin B12 ABC transporter, B12-binding component BtuF

Position: -315
Score: 105.6
Sequence: ACCTTCGCGACTTGT...
Locus tag: PFL_4431
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: PFL_4430
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: PFL_4429
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: PFL_4428
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PFL_4427
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: PFL_4426
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: PFL_4425
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: PFL_4424
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: PFL_4423
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: PFL_4422
Name: cobS
Funciton: Cobalamin synthase
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cbiA
Cobyrinic acid A,C-diamide synthase
bluB
Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
cbiB
Adenosylcobinamide-phosphate synthase
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiP
Cobyric acid synthase
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cobC
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cobS
Cobalamin synthase

Position: -156
Score: 105.3
Sequence: CTACACACCTTGTTA...
Locus tag: PFL_3656
Name: cbtB
Funciton: hypothetical protein
Locus tag: PFL_3657
Name: cbtA
Funciton: Predicted cobalt transporter CbtA
Locus tag: PFL_3658
Name: cobE
Funciton: Cobalamin biosynthesis protein CobE
Locus tag: PFL_3659
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbtB
hypothetical protein
cbtA
Predicted cobalt transporter CbtA
cobE
Cobalamin biosynthesis protein CobE
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
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