Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Pseudomonas aeruginosa PAO1

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Pseudomonadaceae
Under regulation:
- Genes 24
- Operons 5
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -252
Score: 87.8
Sequence: GCATAATAGCGCGTT...
Locus tag: PA2906
Name: cobG
Funciton: Cobalamin biosynthesis protein CobG
Locus tag: PA2905
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: PA2904
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: PA2903
Name: cbiGH
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
PA2906
cobG
Cobalamin biosynthesis protein CobG
PA2905
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
PA2904
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
PA2903
cbiGH
Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
Position: -303
Score: 82.3
Sequence: CTGCGCGCCTTGCGA...
Locus tag: PA1271
Name: btuB2
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: PA1272
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: PA1273
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: PA1274
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: PA1275
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PA1276
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: PA1277
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: PA1278
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: PA1279
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: PA1280
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: PA1281
Name: cobS
Funciton: Cobalamin synthase
PA1271
btuB2
Outer membrane vitamin B12 receptor BtuB
PA1272
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
PA1273
cbiA
Cobyrinic acid A,C-diamide synthase
PA1274
bluB
Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
PA1275
cbiB
Adenosylcobinamide-phosphate synthase
PA1276
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
PA1277
cbiP
Cobyric acid synthase
PA1278
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
PA1279
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
PA1280
cobC
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
PA1281
cobS
Cobalamin synthase
Position: -58
Score: 77.8
Sequence: CTAGGCGGGTTGTCC...
Locus tag: PA2946
Name: cbtA
Funciton: Predicted cobalt transporter CbtA
Locus tag: PA2947
Name: cobE
Funciton: Cobalamin biosynthesis protein CobE
Locus tag: PA2948
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
PA2946
cbtA
Predicted cobalt transporter CbtA
PA2947
cobE
Cobalamin biosynthesis protein CobE
PA2948
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Position: -303
Score: 112.9
Sequence: CCATCCGGCCCGTTC...
Locus tag: PA2911
Name: btuB
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: PA2912
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: PA2913
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: PA2914
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
PA2911
btuB
Outer membrane vitamin B12 receptor BtuB
PA2912
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
PA2913
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
PA2914
btuC
Vitamin B12 ABC transporter, permease component BtuC
Position: -238
Score: 104.6
Sequence: CGTAGCCTTGCCGGT...
Locus tag: PA2945
Name: null
Funciton: CobW GTPase involved in cobalt insertion for B12 biosynthesis
Locus tag: PA2944
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
PA2945
CobW GTPase involved in cobalt insertion for B12 biosynthesis
PA2944
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
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