Regulog BirA - Pseudomonadaceae

Properties
Regulator type:	Transcription factor
Regulator family:	BirA
Regulation mode:	repressor
Biological process:	Biotin biosynthesis
Effector:	Biotin
Phylum:	Proteobacteria/Gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 15 sites [see more]

Member of regulog collections

By trascription factor - BirA
By taxonomy - Pseudomonadaceae
By TF family - BirA
By effector - Biotin
By pathway - Biotin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Pseudomonas aeruginosa PAO1	5	1
Pseudomonas entomophila L48	6	2
Pseudomonas putida KT2440	6	2
Pseudomonas syringae pv. tomato str. DC3000	6	2
Pseudomonas fluorescens Pf-5	6	2
Pseudomonas mendocina ymp	6	2
Pseudomonas stutzeri A1501	6	2
Azotobacter vinelandii AvOP	5	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
PA0490	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	* Pseudomonas mendocina ymp Site: position = -107 score = 8.23801 sequence = CTGTCAACC-(14)-GGTTGACGA Gene: Pmen_4089: Permeases of the major facilitator superfamily	Pseudomonas stutzeri A1501	Azotobacter vinelandii AvOP	Permeases of the major facilitator superfamily
COG1040	Pseudomonas aeruginosa PAO1 Gene: PA0489: Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy	* Pseudomonas entomophila L48 Site: position = 5 score = 8.10836 sequence = CTGTCAACC-(15)-GGCTTACAA Gene: PSEEN5122: Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy	* Pseudomonas putida KT2440 Site: position = 5 score = 8.5622 sequence = CTGTCAACT-(15)-GGTTTACAA Gene: PP0361: Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = 5 score = 8.81229 sequence = CTGTCAACC-(15)-GGTTTACAT Gene: PSPTO0493: Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy	* Pseudomonas fluorescens Pf-5 Site: position = 5 score = 8.81229 sequence = CTGTCAACC-(15)-GGTTTACAT Gene: PFL_5694: Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy	Pseudomonas mendocina ymp Gene: Pmen_4090: Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy	* Pseudomonas stutzeri A1501 Site: position = -21 score = 8.99046 sequence = CTGTCAACC-(14)-GGTTTACAA Gene: PST_3867: Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy	* Azotobacter vinelandii AvOP Site: position = -16 score = 8.99046 sequence = CTGTCAACC-(15)-GGTTTACAA Gene: Avin_05970: Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy	Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy

CRON 2.
bioB	* Pseudomonas aeruginosa PAO1 Site: position = -129 score = 7.4675 sequence = ATGTAGTCC-(14)-GGTTGACAG Gene: PA0500: Biotin synthase (EC 2.8.1.6)	* Pseudomonas entomophila L48 Site: position = -127 score = 8.10836 sequence = TTGTAAGCC-(15)-GGTTGACAG Gene: PSEEN5121: Biotin synthase (EC 2.8.1.6)	* Pseudomonas putida KT2440 Site: position = -127 score = 8.5622 sequence = TTGTAAACC-(15)-AGTTGACAG Gene: PP0362: Biotin synthase (EC 2.8.1.6)	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = -128 score = 8.81229 sequence = ATGTAAACC-(15)-GGTTGACAG Gene: PSPTO0494: Biotin synthase (EC 2.8.1.6)	* Pseudomonas fluorescens Pf-5 Site: position = -128 score = 8.81229 sequence = ATGTAAACC-(15)-GGTTGACAG Gene: PFL_5693: Biotin synthase (EC 2.8.1.6)	* Pseudomonas mendocina ymp Site: position = -119 score = 8.23801 sequence = TCGTCAACC-(14)-GGTTGACAG Gene: Pmen_4088: Biotin synthase (EC 2.8.1.6)	* Pseudomonas stutzeri A1501 Site: position = -104 score = 8.99046 sequence = TTGTAAACC-(14)-GGTTGACAG Gene: PST_3866: Biotin synthase (EC 2.8.1.6)	* Azotobacter vinelandii AvOP Site: position = -139 score = 8.99046 sequence = TTGTAAACC-(15)-GGTTGACAG Gene: Avin_05980: Biotin synthase (EC 2.8.1.6)	Biotin synthase (EC 2.8.1.6)
bioF	Pseudomonas aeruginosa PAO1 Gene: PA0501: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Pseudomonas entomophila L48 Gene: PSEEN5120: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Pseudomonas putida KT2440 Gene: PP0363: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO0495: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Pseudomonas fluorescens Pf-5 Gene: PFL_5692: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Pseudomonas mendocina ymp Gene: Pmen_4087: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Pseudomonas stutzeri A1501 Gene: PST_3865: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Azotobacter vinelandii AvOP Gene: Avin_05990: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	8-amino-7-oxononanoate synthase (EC 2.3.1.47)
bioH	Pseudomonas aeruginosa PAO1 Gene: PA0502: hypothetical protein	Pseudomonas entomophila L48 Gene: PSEEN5119: hypothetical protein	Pseudomonas putida KT2440 Gene: PP0364: hypothetical protein	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO0496: hypothetical protein	Pseudomonas fluorescens Pf-5 Gene: PFL_5691: hypothetical protein	Pseudomonas mendocina ymp Gene: Pmen_4086: hypothetical protein	Pseudomonas stutzeri A1501 Gene: PST_3864: hypothetical protein	Azotobacter vinelandii AvOP Gene: Avin_06000: hypothetical protein	hypothetical protein
bioC	Pseudomonas aeruginosa PAO1 Gene: PA0503: Biotin synthesis protein bioC	Pseudomonas entomophila L48 Gene: PSEEN5118: Biotin synthesis protein bioC	Pseudomonas putida KT2440 Gene: PP0365: Biotin synthesis protein bioC	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO0497: Biotin synthesis protein bioC	Pseudomonas fluorescens Pf-5 Gene: PFL_5690: Biotin synthesis protein bioC	Pseudomonas mendocina ymp Gene: Pmen_4085: Biotin synthesis protein bioC	Pseudomonas stutzeri A1501 Gene: PST_3863: Biotin synthesis protein bioC	Azotobacter vinelandii AvOP Gene: Avin_06010: Biotin synthesis protein bioC	Biotin synthesis protein bioC
bioD	Pseudomonas aeruginosa PAO1 Gene: PA0504: Dethiobiotin synthetase (EC 6.3.3.3)	Pseudomonas entomophila L48 Gene: PSEEN5117: Dethiobiotin synthetase (EC 6.3.3.3)	Pseudomonas putida KT2440 Gene: PP0366: Dethiobiotin synthetase (EC 6.3.3.3)	Pseudomonas syringae pv. tomato str. DC3000 Gene: PSPTO0498: Dethiobiotin synthetase (EC 6.3.3.3)	Pseudomonas fluorescens Pf-5 Gene: PFL_5689: Dethiobiotin synthetase (EC 6.3.3.3)	Pseudomonas mendocina ymp Gene: Pmen_4084: Dethiobiotin synthetase (EC 6.3.3.3)	Pseudomonas stutzeri A1501 Gene: PST_3862: Dethiobiotin synthetase (EC 6.3.3.3)	Azotobacter vinelandii AvOP Gene: Avin_45930: Dethiobiotin synthetase (EC 6.3.3.3)	Dethiobiotin synthetase (EC 6.3.3.3)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog BirA - Pseudomonadaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --