Propagated regulons of Staphylococcus capitis SK14
| Type | Regulator | Effector | Pathway | Genes | Sites |
|---|---|---|---|---|---|
| TF | ArcR | Arginine | Arginine degradation | 1 | 1 |
| TF | ArgR | Arginine | Arginine biosynthesis; Arginine degradation | 6 | 19 |
| TF | ArsR | Arsenate; Arsenite | Arsenic resistance | 1 | 1 |
| TF | BirA | Biotin | Biotin biosynthesis | 3 | 3 |
| TF | BlaI | BlaR, sensor histidine kinase (beta-lactam antibiotics) | Beta-lactam resistance | 2 | 2 |
| TF | CcpA | HPr, phosphocarrier protein; Fructose-1,6-diphosphate | Carbon catabolism | 58 | 67 |
| TF | CggR | Fructose-1,6-diphosphate | Glycolysis | 1 | 1 |
| TF | CodY | Branched-chain amino acids | Amino acid metabolism | 64 | 157 |
| TF | CymR | O-acetyl-L-serine; CysK, cysteine synthetase | Cysteine metabolism | 9 | 11 |
| TF | CzrA | Zinc ion, (Zn2+) | Zinc resistance | 1 | 1 |
| TF | FapR | Malonyl-CoA; Malonyl-ACP | Fatty acid biosynthesis | 5 | 5 |
| TF | FruR | Fructose-6-phosphate | Fructose utilization | 1 | 3 |
| TF | Fur | Iron ion, (Fe2+) | Iron homeostasis | 15 | 19 |
| TF | GlnR | Feedback-inhibited GlnA, glutamine synthetase | Nitrogen assimilation | 2 | 2 |
| TF | GltC | 2-oxoglutarate; Glutamate | Glutamate metabolism | 2 | 2 |
| TF | GlvR | Maltose-6-phosphate | Maltose utilization | 1 | 1 |
| TF | GntR | Gluconate | Gluconate utilization | 1 | 1 |
| TF | HisR | Histidine | Histidine biosynthesis | 3 | 4 |
| TF | HrcA | Heat shock | Heat shock response | 2 | 2 |
| TF | HutR | Histidine | Histidine utilization | 2 | 4 |
| TF | IcaR | Intercellular adhesion | 2 | 2 | |
| TF | LexA | DNA damage | SOS response | 10 | 14 |
| TF | MntR | Manganese ion, (Mn2+) | Manganese homeostasis | 2 | 2 |
| TF | MtlR | MtlA, mannitol-specific enzyme IICB PTS component; HPr, phosphocarrier protein | Mannitol utilization | 1 | 1 |
| TF | MurR | N-acetylmuramate-6-phosphate | N-acetylmuramate utilization | 1 | 1 |
| TF | NrdR | Deoxyribonucleotides | Deoxyribonucleotide biosynthesis | 2 | 2 |
| TF | NreC | NreB, sensor histidine kinase (Nitrate, Nitrite) | Nitrate and nitrite respiration | 3 | 3 |
| TF | PerR | Hydrogen peroxide; Manganese ion, (Mn2+); Iron ion, (Fe2+) | Oxidative stress response | 9 | 13 |
| TF | Rex | NADH | Energy metabolism | 10 | 12 |
| TF | SaeR | SaeS, sensor histidine kinase | Virulence | 3 | 5 |
| TF | ScrR | Sucrose-6-phosphate | Sucrose utilization | 2 | 2 |
| TF | YtrA | Hypothetical ABC transporter | 1 | 1 | |
| TF | Zur | Zinc ion, (Zn2+) | Zinc homeostasis | 9 | 9 |