Regulon of MetR in Pseudomonas putida KT2440

Properties
Regulator type:	Transcription factor
TF locus tag:	PP1063, PP2696
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Methionine biosynthesis
Effector:	Homocysteine
Regulog:	MetR - Pseudomonadaceae
Statistics of regulated genes:
- Genes	11
- Operons	6
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 44 sites [see more]

Member of regulog collections

By taxonomy - Pseudomonadaceae
By trascription factor - MetR
By TF family - LysR
By effector - Homocysteine
By pathway - Methionine biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -172 Score: 5.2 Sequence: ATTGAGACAAACTCATT Position: -152 Score: 4 Sequence: TTTGAGATGAACCCAAG Locus tag: PP4638 Name: metF2 Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
	PP4638	metF2	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -92 Score: 4 Sequence: CTTGGGTTCATCTCAAA Position: -72 Score: 5.2 Sequence: AATGAGTTTGTCTCAAT Locus tag: PP4637 Name: metE2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	PP4637	metE2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Position: -119 Score: 4.7 Sequence: GATGAATGTTTTTCATG Locus tag: PP1469 Name: dsbC Funciton: Thiol:disulfide interchange protein DsbC Locus tag: PP1470 Name: hom Funciton: Homoserine dehydrogenase (EC 1.1.1.3) Locus tag: PP1471 Name: thrC Funciton: Threonine synthase (EC 4.2.3.1)
	PP1469	dsbC	Thiol:disulfide interchange protein DsbC
	PP1470	hom	Homoserine dehydrogenase (EC 1.1.1.3)
	PP1471	thrC	Threonine synthase (EC 4.2.3.1)
Position: -98 Score: 4.4 Sequence: CATGAGCAGTTTTCATG Locus tag: PP2375 Name: metH Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase, B12-dependent (EC 2.1.1.13)
	PP2375	metH	5-methyltetrahydrofolate--homocysteine methyltransferase, B12-dependent (EC 2.1.1.13)
Position: -76 Score: 3.9 Sequence: TGTGAAATAACTTCAAT Position: -66 Score: 4.1 Sequence: CTTCAATATCATTCATG Locus tag: PP2699 Name: PF08908 Funciton: Protein of unknown function DUF1852 Locus tag: PP2698 Name: metE2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) Locus tag: PP2697 Name: PF01613 Funciton: Flavin reductase-like, FMN-binding Locus tag: PP2696 Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
	PP2699	PF08908	Protein of unknown function DUF1852
	PP2698	metE2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	PP2697	PF01613	Flavin reductase-like, FMN-binding
	PP2696	metR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -57 Score: 5.3 Sequence: CATGAGAGAAACTCAAT Position: 17 Score: 3.8 Sequence: CCTGAAAACCCTTCATG Locus tag: PP1063 Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
	PP1063	metR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

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