Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetR in Actinobacillus pleuropneumoniae serovar 7 str. AP76

Properties
Regulator type: Transcription factor
TF locus tag: APP7_1216
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Methionine biosynthesis
Effector: Homocysteine
Regulog: MetR - Pasteurellales
Statistics of regulated genes:
- Genes 7
- Operons 7
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 40 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -70
Score: 4.9
Sequence: ATGACATATTTTCAT
Locus tag: APP7_1441
Name: HI0736
Funciton: hypothetical sodium-dependent transporter
HI0736
hypothetical sodium-dependent transporter

Position: -139
Score: 4.8
Sequence: ATTATTTTTATTCAT
Position: -104
Score: 5.5
Sequence: ATGAATATAATTCAT
Locus tag: APP7_0911
Name: metE2
Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
metE2
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

Position: -121
Score: 5.5
Sequence: ATGAATTAATTTCAT
Locus tag: APP7_0324
Name: metE2-2
Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
metE2-2
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

Position: -131
Score: 4.9
Sequence: ATTAATATGTTTCAT
Locus tag: APP7_1214
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -13
Score: 4.8
Sequence: ATGAATTATTTACAT
Locus tag: APP7_1216
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -153
Score: 5.2
Sequence: ATTAATTTTTTTCAT
Locus tag: APP7_0213
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)

Position: -139
Score: 5.5
Sequence: ATGAATTATATTCAT
Position: -104
Score: 4.8
Sequence: ATGAATAAAAATAAT
Locus tag: APP7_0912
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
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