Regulog MetR - Pasteurellales
| Regulator type: | Transcription factor |
| Regulator family: | LysR |
| Regulation mode: | repressor (activator) |
| Biological process: | Methionine biosynthesis |
| Effector: | Homocysteine |
| Phylum: | Proteobacteria/Gamma |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Pasteurellales
- By trascription factor - MetR
- By TF family - LysR
- By effector - Homocysteine
- By pathway - Methionine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Haemophilus influenzae Rd KW20 | 5 | 5 |
| Aggregatibacter aphrophilus NJ8700 | 4 | 4 |
| Pasteurella multocida subsp. multocida str. Pm70 | 4 | 4 |
| Mannheimia succiniciproducens MBEL55E | 5 | 5 |
| Actinobacillus succinogenes 130Z | 2 | 2 |
| Haemophilus somnus 2336 | 3 | 3 |
| Actinobacillus pleuropneumoniae serovar 7 str. AP76 | 7 | 7 |
| Haemophilus ducreyi 35000HP | ||
| Haemophilus parasuis SH0165 | 2 | 2 |
| Genes | Function | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||
| glyA |
*
Haemophilus influenzae Rd KW20 Site: position = -109 score = 5.49937 sequence = ATGAATTAATTTCAT Gene: HI0889: Serine hydroxymethyltransferase (EC 2.1.2.1) |
*
Aggregatibacter aphrophilus NJ8700 Site: position = -114 score = 4.87918 sequence = GTGAAAATTTTTCAT Gene: NT05HA_1325: Serine hydroxymethyltransferase (EC 2.1.2.1) |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -119 score = 5.46053 sequence = ATGAATTTTTTTCAT Gene: PM0225: Serine hydroxymethyltransferase (EC 2.1.2.1) |
*
Mannheimia succiniciproducens MBEL55E Site: position = -103 score = 4.54964 sequence = CTTAATTAATTTCAT Gene: MS1295: Serine hydroxymethyltransferase (EC 2.1.2.1) |
Gene: Asuc_1360: Serine hydroxymethyltransferase (EC 2.1.2.1) |
*
Haemophilus somnus 2336 Site: position = -112 score = 5.42558 sequence = ATGAAATTTTTTCAT Gene: HSM_0382: Serine hydroxymethyltransferase (EC 2.1.2.1) |
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -153 score = 5.19542 sequence = ATTAATTTTTTTCAT Gene: APP7_0213: Serine hydroxymethyltransferase (EC 2.1.2.1) |
|
Gene: HAPS_0379: Serine hydroxymethyltransferase (EC 2.1.2.1) |
Serine hydroxymethyltransferase (EC 2.1.2.1) |
| CRON 2. | ||||||||||
| metE |
*
Haemophilus influenzae Rd KW20 Site: position = -128 score = 5.23426 sequence = ATGAATTTATTTAAT Gene: HI1702: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
*
Aggregatibacter aphrophilus NJ8700 Site: position = -122 score = 5.15658 sequence = ATTAAAATTATTCAT Gene: NT05HA_0341: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -132 score = 5.12163 sequence = ATTAAAAATTTTCAT Gene: PM0420: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
|
|
*
Haemophilus somnus 2336 Site: position = -129 score = 5.19542 sequence = ATTAATTTTTTTCAT Gene: HSM_1293: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -131 score = 4.94346 sequence = ATTAATATGTTTCAT Gene: APP7_1214: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
|
*
Haemophilus parasuis SH0165 Site: position = -136 score = 5.38674 sequence = ATGAAAAATTTTCAT Gene: HAPS_1354: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
| CRON 3. | ||||||||||
| metR |
*
Haemophilus influenzae Rd KW20 Site: position = -13 score = 5.19153 sequence = ATGAATATTATTAAT Site: position = -82 score = 4.96527 sequence = ATTAATTTTATTAAT Gene: HI1739: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
*
Aggregatibacter aphrophilus NJ8700 Site: position = -157 score = 5.15658 sequence = ATGAATAATTTTAAT Gene: NT05HA_0342: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -13 score = 4.94346 sequence = ATGAATCTTTTTAAT Site: position = -181 score = 5.12163 sequence = ATGAAAATTTTTAAT Gene: PM0421: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
*
Mannheimia succiniciproducens MBEL55E Site: position = -13 score = 4.51704 sequence = ATGAATTATTCTAAT Gene: MS0763: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
Gene: Asuc_1680: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
Gene: HSM_1538: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -13 score = 4.76989 sequence = ATGAATTATTTACAT Gene: APP7_1216: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
|
Gene: HAPS_2191: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
| CRON 4. | ||||||||||
| metE2 |
|
|
|
*
Mannheimia succiniciproducens MBEL55E Site: position = -30 score = 5.07657 sequence = ATAAAATTTATTCAT Site: position = -104 score = 4.78233 sequence = ATGAATCCGTTTCAT Gene: MS0941: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
*
Actinobacillus succinogenes 130Z Site: position = -30 score = 4.94346 sequence = ATTAAAACTATTCAT Site: position = -105 score = 4.78233 sequence = ATGAATCCGTTTCAT Gene: Asuc_1191: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
|
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -104 score = 5.49547 sequence = ATGAATATAATTCAT Site: position = -139 score = 4.77739 sequence = ATTATTTTTATTCAT Gene: APP7_0911: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
|
|
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
| CRON 5. | ||||||||||
| HI0736 |
*
Haemophilus influenzae Rd KW20 Site: position = -55 score = 4.79443 sequence = ATGATTAGATTTCAT Gene: HI0736: hypothetical sodium-dependent transporter |
Gene: NT05HA_1978: hypothetical sodium-dependent transporter |
Gene: PM0718: hypothetical sodium-dependent transporter |
*
Mannheimia succiniciproducens MBEL55E Site: position = -110 score = 5.07657 sequence = ATAAAAATAATTCAT Gene: MS2382: hypothetical sodium-dependent transporter |
Gene: Asuc_0284: hypothetical sodium-dependent transporter |
Gene: HSM_1866: hypothetical sodium-dependent transporter |
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -70 score = 4.85723 sequence = ATGACATATTTTCAT Gene: APP7_1441: hypothetical sodium-dependent transporter |
|
|
hypothetical sodium-dependent transporter |
| CRON 6. | ||||||||||
| metE2-2 |
|
|
|
|
*
Actinobacillus succinogenes 130Z Site: position = -128 score = 5.32119 sequence = ATGAATTGAATTCAT Gene: Asuc_0713: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
|
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -121 score = 5.49937 sequence = ATGAATTAATTTCAT Gene: APP7_0324: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
|
|
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
| CRON 7. | ||||||||||
| metF |
*
Haemophilus influenzae Rd KW20 Site: position = -100 score = 4.73855 sequence = ATTAATAATAATCAT Gene: HI1444: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
*
Aggregatibacter aphrophilus NJ8700 Site: position = -106 score = 4.97841 sequence = ATTAATCTTATTCAT Gene: NT05HA_0300: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -109 score = 5.32119 sequence = ATGAATTGAATTCAT Gene: PM0235: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
*
Mannheimia succiniciproducens MBEL55E Site: position = -124 score = 5.26921 sequence = ATTAATTAAATTCAT Gene: MS0787: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
|
*
Haemophilus somnus 2336 Site: position = -199 score = 4.46704 sequence = ACAAAAAAATTTCAT Site: position = -111 score = 5.53431 sequence = ATGAATTTAATTCAT Gene: HSM_1047: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -139 score = 5.49547 sequence = ATGAATTATATTCAT Site: position = -104 score = 4.77739 sequence = ATGAATAAAAATAAT Gene: APP7_0912: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
|
*
Haemophilus parasuis SH0165 Site: position = -154 score = 5.15036 sequence = ATAAATTAAATTCAT Site: position = -186 score = 4.43702 sequence = TTTAAAAATTTTCAT Gene: HAPS_2275: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |