Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of LiuR in Shewanella sp MR-4

Properties
Regulator type: Transcription factor
TF locus tag: Shewmr4_2321
Regulator family: MerR
Regulation mode: repressor
Biological process: Branched-chain amino acid degradation
Effector:
Regulog: LiuR - Shewanellaceae
Statistics of regulated genes:
- Genes 29
- Operons 9
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 134 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -188
Score: 5.7
Sequence: GTTAACGTTAACGTCAAG
Locus tag: Shewmr4_2872
Name: gltB
Funciton: glutamate synthase, large subunit
Locus tag: Shewmr4_2873
Name: gltD
Funciton: glutamate synthase, small subunit
gltB
glutamate synthase, large subunit
gltD
glutamate synthase, small subunit

Position: -90
Score: 6.2
Sequence: GTTTACGTTAACGTAATG
Locus tag: Shewmr4_2028
Name: bkdA1
Funciton: 3-methyl-2-oxobutanoate dehydrogenase complex, E1 component, alpha subunit
Locus tag: Shewmr4_2027
Name: bkdA2
Funciton: 3-methyl-2-oxobutanoate dehydrogenase complex, E1 component, beta subuni
Locus tag: Shewmr4_2026
Name: bkdB
Funciton: 3-methyl-2-oxobutanoate dehydrogenase complex, E2 component
bkdA1
3-methyl-2-oxobutanoate dehydrogenase complex, E1 component, alpha subunit
bkdA2
3-methyl-2-oxobutanoate dehydrogenase complex, E1 component, beta subuni
bkdB
3-methyl-2-oxobutanoate dehydrogenase complex, E2 component

Position: -171
Score: 6
Sequence: CCTTACGTTTACGTAAAG
Locus tag: Shewmr4_1598
Name: ldh
Funciton: leucine dehydrogenase
ldh
leucine dehydrogenase

Position: -524
Score: 5.7
Sequence: GTTTACGTAAACGTAATA
Locus tag: Shewmr4_2767
Name: aceB
Funciton: malate synthase A
Locus tag: Shewmr4_2766
Name: null
Funciton: isocitrate lyase
aceB
malate synthase A
isocitrate lyase

Position: -373
Score: 5.7
Sequence: CATTACGTTTACGTCAAC
Locus tag: Shewmr4_1138
Name: thrA
Funciton: aspartate kinase
Locus tag: Shewmr4_1139
Name: thrB
Funciton: homoserine kinase
Locus tag: Shewmr4_1140
Name: thrC
Funciton: threonine synthase
thrA
aspartate kinase
thrB
homoserine kinase
thrC
threonine synthase

Position: -59
Score: 6
Sequence: CTTTACCTTTACGTAAAC
Locus tag: Shewmr4_2321
Name: liuR
Funciton: branched chain amino acid metabolism regulator, MerR family
Locus tag: Shewmr4_2322
Name: liuA
Funciton: isovaleryl-CoA dehydrogenase
Locus tag: Shewmr4_2323
Name: liuB
Funciton: 3-methylcrotonyl CoA carboxylase, beta subunit
Locus tag: Shewmr4_2324
Name: liuC
Funciton: methylglutaconyl-CoA hydratase
Locus tag: Shewmr4_2325
Name: liuD
Funciton: methylcrotonyl-CoA carboxylase, biotin-containing subunit
Locus tag: Shewmr4_2326
Name: liuE
Funciton: hydroxymethylglutaryl-CoA lyase
Locus tag: Shewmr4_2327
Name: liuF
Funciton: acetyl-CoA:acetoacetate-CoA transferase, beta subunit
Locus tag: Shewmr4_2328
Name: liuG
Funciton: acetyl-CoA:acetoacetate-CoA transferase, alpha subunit
liuR
branched chain amino acid metabolism regulator, MerR family
liuA
isovaleryl-CoA dehydrogenase
liuB
3-methylcrotonyl CoA carboxylase, beta subunit
liuC
methylglutaconyl-CoA hydratase
liuD
methylcrotonyl-CoA carboxylase, biotin-containing subunit
liuE
hydroxymethylglutaryl-CoA lyase
liuF
acetyl-CoA:acetoacetate-CoA transferase, beta subunit
liuG
acetyl-CoA:acetoacetate-CoA transferase, alpha subunit

Position: -96
Score: 5.9
Sequence: CTTTACGTTCGCGTAAAC
Locus tag: Shewmr4_2597
Name: ivdA
Funciton: 3-ketoacyl-CoA thiolase
Locus tag: Shewmr4_2596
Name: ivdB
Funciton: methylmalonate-semialdehyde dehydrogenase
Locus tag: Shewmr4_2595
Name: ivdC
Funciton: branched-chain acyl-CoA dehydrogenase
Locus tag: Shewmr4_2594
Name: ivdD
Funciton: enoyl-CoA hydratase
Locus tag: Shewmr4_2593
Name: ivdE
Funciton: 3-hydroxyisobutyryl-CoA hydrolase
Locus tag: Shewmr4_2592
Name: ivdF
Funciton: 3-hydroxyisobutyrate dehydrogenase
Locus tag: Shewmr4_2591
Name: ivdG
Funciton: 3-hydroxyacyl-CoA dehydrogenase
ivdA
3-ketoacyl-CoA thiolase
ivdB
methylmalonate-semialdehyde dehydrogenase
ivdC
branched-chain acyl-CoA dehydrogenase
ivdD
enoyl-CoA hydratase
ivdE
3-hydroxyisobutyryl-CoA hydrolase
ivdF
3-hydroxyisobutyrate dehydrogenase
ivdG
3-hydroxyacyl-CoA dehydrogenase

Position: -137
Score: 5.7
Sequence: TTTTACGTTTGCGTAAAC
Locus tag: Shewmr4_2605
Name: tyrR
Funciton: aromatic amino acid biosynthesis/transport transciptional regulator
tyrR
aromatic amino acid biosynthesis/transport transciptional regulator

Position: -98
Score: 5.7
Sequence: GTTGACGTTAACGTTAAC
Locus tag: Shewmr4_1352
Name: etfB
Funciton: electron transfer flavoprotein, beta subunit
Locus tag: Shewmr4_1353
Name: etfA
Funciton: electron transfer flavoprotein, alpha subunit
etfB
electron transfer flavoprotein, beta subunit
etfA
electron transfer flavoprotein, alpha subunit
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