Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of LiuR in Pseudoalteromonas tunicata D2

Properties
Regulator type: Transcription factor
TF locus tag: PTD2_19757
Regulator family: MerR
Regulation mode: repressor
Biological process: Branched-chain amino acid degradation
Effector:
Regulog: LiuR - Alteromonadales
Statistics of regulated genes:
- Genes 26
- Operons 9
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 65 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -104
Score: 5.7
Sequence: GTTGACGTAAACGTCAAC
Locus tag: PTD2_19430
Name: etfD
Funciton: Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)
etfD
Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)

Position: -55
Score: 6
Sequence: CTTTACCTTTACGTAAAC
Locus tag: PTD2_19757
Name: liuR
Funciton: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
Locus tag: PTD2_19762
Name: liuA
Funciton: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
Locus tag: PTD2_19767
Name: liuB
Funciton: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
Locus tag: PTD2_19772
Name: liuC
Funciton: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
Locus tag: PTD2_19777
Name: liuD
Funciton: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
Locus tag: PTD2_19782
Name: liuE
Funciton: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
Locus tag: PTD2_19787
Name: liuF
Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
Locus tag: PTD2_19792
Name: liuG
Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)
liuR
Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
liuA
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
liuB
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
liuC
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
liuD
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
liuE
Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
liuF
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
liuG
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)

Position: -66
Score: 5.3
Sequence: ATTTACGTTGGCGTAAAC
Locus tag: PTD2_19752
Name: ivdA
Funciton: 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
Locus tag: PTD2_19747
Name: ivdB
Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
Locus tag: PTD2_19742
Name: ivdC
Funciton: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
Locus tag: PTD2_19737
Name: ivdD
Funciton: Enoyl-CoA hydratase (EC 4.2.1.17)
Locus tag: PTD2_19732
Name: ivdE
Funciton: Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
Locus tag: PTD2_19727
Name: ivdF
Funciton: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Locus tag: PTD2_19722
Name: ivdG
Funciton: 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)
ivdA
3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
ivdB
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
ivdC
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
ivdD
Enoyl-CoA hydratase (EC 4.2.1.17)
ivdE
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
ivdF
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
ivdG
3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

Position: -140
Score: 5.6
Sequence: GTTAACCTTTACGTAAAC
Locus tag: PTD2_08574
Name: null
Funciton: hypothetical protein
Locus tag: PTD2_08579
Name: null
Funciton: Sodium:solute symporter family protein
hypothetical protein
Sodium:solute symporter family protein

Position: -54
Score: 6
Sequence: CTTTACGTTTACGTTAAC
Locus tag: PTD2_03281
Name: tyrP
Funciton: Tyrosine-specific transport protein (HAAAP family)
tyrP
Tyrosine-specific transport protein (HAAAP family)

Position: -297
Score: 6.3
Sequence: GTTTACGTTTACGTAAAC
Position: -291
Score: 4.7
Sequence: GTTTACGTAAACTTACTC
Locus tag: PTD2_10749
Name: gltB
Funciton: Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
Locus tag: PTD2_10744
Name: gltD
Funciton: Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
gltB
Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
gltD
Glutamate synthase [NADPH] small chain (EC 1.4.1.13)

Position: -80
Score: 5.4
Sequence: GTTAAAGTTAACGTAAAC
Locus tag: PTD2_18015
Name: yciK
Funciton: Oxidoreductase, short-chain dehydrogenase/reductase family
yciK
Oxidoreductase, short-chain dehydrogenase/reductase family

Position: -246
Score: 6.1
Sequence: TTTTACGTTAACGTAAAC
Locus tag: PTD2_18100
Name: ldh
Funciton: Leucine dehydrogenase (EC 1.4.1.9)
ldh
Leucine dehydrogenase (EC 1.4.1.9)

Position: -224
Score: 6.4
Sequence: GTTTACGTTAACGTAAAG
Locus tag: PTD2_19360
Name: bkdA1
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
Locus tag: PTD2_19365
Name: bkdA2
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
Locus tag: PTD2_19370
Name: bkdB
Funciton: Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
bkdA1
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
bkdA2
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
bkdB
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
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