Regulog CymR - Clostridia-1
| Regulator type: | Transcription factor |
| Regulator family: | Rrf2 |
| Regulation mode: | repressor |
| Biological process: | Cysteine metabolism |
| Effector: | |
| Phylum: | Firmicutes |
| Visualization: | |
|
Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Clostridia-1
- By TF family - Rrf2
- By pathway - Cysteine metabolism
| Genome | Genes | Operons |
|---|---|---|
| Clostridium acetobutylicum ATCC 824 | 20 | 6 |
| Clostridium beijerincki NCIMB 8052 | 5 | 4 |
| Clostridium botulinum A str. ATCC 3502 | 4 | 2 |
| Clostridium butyricum 5521 | 9 | 2 |
| Clostridium kluyveri DSM 555 | ||
| Clostridium novyi NT | ||
| Clostridium perfringens ATCC 13124 | ||
| Clostridium tetani E88 | 1 | 1 |
| Genes | Function | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | |||||||||
| sbpA |
|
*2
Clostridium beijerincki NCIMB 8052 Site: position = -98 score = 5.80464 sequence = AAAATCCTACTAAACATATATGAATAT Gene: Cbei_4193: Sulfate-binding protein Sbp Site: position = -170 score = 5.29586 sequence = TAATTCCCATTGAAATAATAGGAATTA Gene: Cbei_4194: Sulfate-binding protein Sbp |
|
|
|
|
|
|
Sulfate-binding protein Sbp |
| CRON 2. | |||||||||
| metY |
*
Clostridium acetobutylicum ATCC 824 Site: position = -77 score = 5.04179 sequence = CATTACATAGTAAAGTAATATGTTTTA Site: position = -277 score = 5.70855 sequence = ATATTCATATTAATATAGTAGGAATTA Gene: CAC0102: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) |
|
|
|
|
|
|
|
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) |
| cysC |
Gene: CAC0103: Adenylylsulfate kinase (EC 2.7.1.25) |
|
|
|
Gene: CKL_1799: Adenylylsulfate kinase (EC 2.7.1.25) |
|
|
|
Adenylylsulfate kinase (EC 2.7.1.25) |
| aprA |
Gene: CAC0104: Adenylylsulfate reductase alpha-subunit (EC 1.8.99.2) |
Gene: Cbei_4189: Adenylylsulfate reductase alpha-subunit (EC 1.8.99.2) |
|
Gene: CBY_3242: Adenylylsulfate reductase alpha-subunit (EC 1.8.99.2) |
Gene: CKL_1798: Adenylylsulfate reductase alpha-subunit (EC 1.8.99.2) |
|
|
|
Adenylylsulfate reductase alpha-subunit (EC 1.8.99.2) |
| aprB |
Gene: CAC0105: Adenylylsulfate reductase beta-subunit (EC 1.8.99.2) |
|
|
Gene: CBY_3243: Adenylylsulfate reductase beta-subunit (EC 1.8.99.2) |
Gene: CKL_1797: Adenylylsulfate reductase beta-subunit (EC 1.8.99.2) |
|
|
|
Adenylylsulfate reductase beta-subunit (EC 1.8.99.2) |
| CAC0106 |
Gene: CAC0106: ABC-type probable sulfate transporter, periplasmic binding protein |
|
|
|
|
|
|
|
ABC-type probable sulfate transporter, periplasmic binding protein |
| CAC0107 |
Gene: CAC0107: ABC-type probable sulfate transporter, ATPase component |
|
|
|
|
|
|
|
ABC-type probable sulfate transporter, ATPase component |
| CAC0108 |
Gene: CAC0108: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component |
|
|
|
|
|
|
|
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component |
| cysD |
Gene: CAC0109: Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) |
|
|
|
Gene: CKL_1796: Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) |
|
|
|
Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) |
| cysN |
Gene: CAC0110: Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) |
|
|
|
Gene: CKL_1795: Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) |
|
|
|
Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) |
| cysT |
|
Gene: Cbei_4192: Sulfate transport system permease protein CysT |
|
*
Clostridium butyricum 5521 Site: position = -81 score = 5.59672 sequence = TAATTCATAGTAATTCTATAAGAATAA Gene: CBY_3239: Sulfate transport system permease protein CysT |
Gene: CKL_1802: Sulfate transport system permease protein CysT |
|
|
|
Sulfate transport system permease protein CysT |
| cysW |
|
Gene: Cbei_4191: Sulfate transport system permease protein CysW |
|
Gene: CBY_3240: Sulfate transport system permease protein CysW |
Gene: CKL_1801: Sulfate transport system permease protein CysW |
|
|
|
Sulfate transport system permease protein CysW |
| cysA |
|
Gene: Cbei_4190: Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) |
|
Gene: CBY_3241: Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) |
Gene: CKL_1800: Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) |
|
|
|
Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25) |
| cysD |
|
Gene: Cbei_4187: Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) |
|
Gene: CBY_3244: sulfate adenylyltransferase, small subunit |
|
|
|
|
Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) |
| cysN |
|
Gene: Cbei_4186: Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) |
|
Gene: CBY_3245: Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) |
|
|
|
|
Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) |
| CRON 3. | |||||||||
| tcyP |
|
*
Clostridium beijerincki NCIMB 8052 Site: position = -48 score = 5.29715 sequence = ATAAATATACTAATTATATAGGAATTG Gene: Cbei_4344: L-cystine uptake protein TcyP |
|
|
|
|
Gene: CPF_1191: L-cystine uptake protein TcyP |
|
L-cystine uptake protein TcyP |
| CRON 4. | |||||||||
| CAC3325 |
*
Clostridium acetobutylicum ATCC 824 Site: position = -354 score = 5.58509 sequence = GTATACCTACTTGTATACTAGGAATAT Gene: CAC3325: L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA |
|
|
|
|
|
|
|
L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA |
| CAC3326 |
Gene: CAC3326: L-Cystine ABC transporter, permease protein TcyB |
|
|
|
|
|
|
|
L-Cystine ABC transporter, permease protein TcyB |
| CAC3327 |
Gene: CAC3327: L-Cystine ABC transporter, ATP-binding protein TcyC |
|
|
|
|
|
|
|
L-Cystine ABC transporter, ATP-binding protein TcyC |
| CRON 5. | |||||||||
| cysK |
*
Clostridium acetobutylicum ATCC 824 Site: position = -49 score = 5.83312 sequence = ATATTCCTAGTAAACAAATGTGTTTAA Gene: CAC2235: Cysteine synthase (EC 2.5.1.47) |
|
*
Clostridium botulinum A str. ATCC 3502 Site: position = -303 score = 5.93953 sequence = GAATACCTAGTAAACAAATAAGAATAA Gene: CBO1179: Cysteine synthase (EC 2.5.1.47) |
|
|
Gene: NT01CX_0572: Cysteine synthase (EC 2.5.1.47) |
|
Gene: CTC01343: Cysteine synthase (EC 2.5.1.47) |
Cysteine synthase (EC 2.5.1.47) |
| CAC0878 |
*
Clostridium acetobutylicum ATCC 824 Site: position = -70 score = 5.77605 sequence = TTAAACATATTAGTTTAGTAGGTATTT Gene: CAC0878: Cysteine ABC transporter permease component |
|
Gene: CBO1180: Cysteine ABC transporter permease component |
|
|
|
|
|
Cysteine ABC transporter permease component |
| CAC0880 |
Gene: CAC0880: Cysteine ABC transporter, substrate-binding protein |
|
Gene: CBO1181: Cysteine ABC transporter, substrate-binding protein |
|
|
|
|
|
Cysteine ABC transporter, substrate-binding protein |
| CAC0879 |
Gene: CAC0879: Cysteine ABC transporter, ATPase component |
|
|
|
|
|
|
|
Cysteine ABC transporter, ATPase component |
| CRON 6. | |||||||||
| ubiG |
*
Clostridium acetobutylicum ATCC 824 Site: position = -473 score = 5.36547 sequence = AAAAACCTACTTATCAGATATGAAAAA Gene: CAC0929: SAM-dependent methlytransferase UbiG |
|
Gene: CBO0727: SAM-dependent methlytransferase UbiG |
|
Gene: CKL_1001: SAM-dependent methlytransferase UbiG |
|
Gene: CPF_0168: SAM-dependent methlytransferase UbiG |
|
SAM-dependent methlytransferase UbiG |
| mccB |
Gene: CAC0930: Cystathionine gamma-lyase (EC 4.4.1.1) |
*
Clostridium beijerincki NCIMB 8052 Site: position = -140 score = 5.67029 sequence = TAAAACACAGTAAACAAATAAGAATAA Gene: Cbei_0629: Cystathionine gamma-lyase (EC 4.4.1.1) |
Gene: CBO0726: Cystathionine gamma-lyase (EC 4.4.1.1) |
*
Clostridium butyricum 5521 Site: position = -100 score = 5.52502 sequence = TAATTCCAAGTAAACAAATAGTAATAG Gene: CBY_1162: Cystathionine gamma-lyase (EC 4.4.1.1) |
Gene: CKL_1002: Cystathionine gamma-lyase (EC 4.4.1.1) |
|
Gene: CPF_0169: Cystathionine gamma-lyase (EC 4.4.1.1) |
|
Cystathionine gamma-lyase (EC 4.4.1.1) |
| CAC0931 |
Gene: CAC0931: Cystathionine beta-synthase (EC 4.2.1.22) |
Gene: Cbei_0630: Cystathionine beta-synthase (EC 4.2.1.22) |
|
|
|
|
Gene: CPF_0170: Cystathionine beta-synthase (EC 4.2.1.22) |
|
Cystathionine beta-synthase (EC 4.2.1.22) |
| mccA |
|
|
Gene: CBO0724: Cystathionine beta-synthase (EC 4.2.1.22) |
Gene: CBY_1163: Cystathionine beta-synthase (EC 4.2.1.22) |
Gene: CKL_1003: Cystathionine beta-synthase (EC 4.2.1.22) |
|
|
|
Cystathionine beta-synthase (EC 4.2.1.22) |
| CRON 7. | |||||||||
| cymR |
*
Clostridium acetobutylicum ATCC 824 Site: position = -86 score = 5.30689 sequence = AAAATTCTACTTGACAAGTAAAATTTT Gene: CAC2236: Predicted transcriptional regulator of cysteine synthase, Rrf2 family |
Gene: Cbei_1748: Predicted transcriptional regulator of cysteine synthase, Rrf2 family |
*
Clostridium botulinum A str. ATCC 3502 Site: position = -45 score = 5.74509 sequence = ATAATCATAGTAAATAGATAGGAATAC Gene: CBO1178: Predicted transcriptional regulator of cysteine synthase, Rrf2 family |
Gene: CBY_1066: Predicted transcriptional regulator of cysteine synthase, Rrf2 family |
|
|
|
*
Clostridium tetani E88 Site: position = -40 score = 5.77564 sequence = ATAATCATACTAAACATATAGGAATAG Gene: CTC01344: Predicted transcriptional regulator of cysteine synthase, Rrf2 family |
Predicted transcriptional regulator of cysteine synthase, Rrf2 family |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
|
Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
|
Regulatory Sites | [ FASTA format ] | DOWNLOAD |