Regulog MtlR - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	BglG
Regulation mode:	activator
Biological process:	Mannitol utilization
Effector:	MtlA, mannitol-specific enzyme IICB PTS component; HPr, phosphocarrier protein
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 5 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By TF family - BglG
By effector - MtlA, mannitol-specific enzyme IICB PTS component
By effector - HPr, phosphocarrier protein
By pathway - Mannitol utilization

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	4	1
Staphylococcus capitis SK14	4	1
Staphylococcus epidermidis ATCC 12228
Staphylococcus carnosus subsp. carnosus TM300	4	1
Staphylococcus haemolyticus JCSC1435	4	1
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	4	1
Macrococcus caseolyticus JCSC5402

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
mtlF	* Staphylococcus aureus subsp. aureus N315 Site: position = -104 score = 6.47731 sequence = TTGTCACATTTATTTTGACAA Gene: SA1960: mannitol specific PTS system, IIBC component	* Staphylococcus capitis SK14 Site: position = -108 score = 6.1949 sequence = TTGTCACAAATATCATGACAA Gene: STACA0001_0858: mannitol specific PTS system, IIBC component	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -105 score = 5.26619 sequence = ATGGCAACAATTCAGTGACAA Gene: Sca_1658: mannitol specific PTS system, IIBC component	* Staphylococcus haemolyticus JCSC1435 Site: position = -105 score = 6.79543 sequence = TTGTCACAATTACTGTGACAA Gene: SH0235: mannitol specific PTS system, IIBC component	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -106 score = 6.57626 sequence = TTGTCAAAGATACTGTGACAA Gene: SSP0728: mannitol specific PTS system, IIBC component	Macrococcus caseolyticus JCSC5402	mannitol specific PTS system, IIBC component
mtlR	Staphylococcus aureus subsp. aureus N315 Gene: SA1961: transcriptional activator of mannitol operon, BglG family	Staphylococcus capitis SK14 Gene: STACA0001_0859: transcriptional activator of mannitol operon, BglG family	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1659: transcriptional activator of mannitol operon, BglG family	Staphylococcus haemolyticus JCSC1435 Gene: SH0234: transcriptional activator of mannitol operon, BglG family	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0727: transcriptional activator of mannitol operon, BglG family	Macrococcus caseolyticus JCSC5402	transcriptional activator of mannitol operon, BglG family
mtlA	Staphylococcus aureus subsp. aureus N315 Gene: SA1962: mannitol specific PTS system, IIA component	Staphylococcus capitis SK14 Gene: STACA0001_0860: mannitol specific PTS system, IIA component	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1660: mannitol specific PTS system, IIA component	Staphylococcus haemolyticus JCSC1435 Gene: SH0233: mannitol specific PTS system, IIA component	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0726: mannitol specific PTS system, IIA component	Macrococcus caseolyticus JCSC5402	mannitol specific PTS system, IIA component
mtlD	Staphylococcus aureus subsp. aureus N315 Gene: SA1963: mannitol-1-phosphate 5-dehydrogenase	Staphylococcus capitis SK14 Gene: STACA0001_0861: mannitol-1-phosphate 5-dehydrogenase	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1661: mannitol-1-phosphate 5-dehydrogenase	Staphylococcus haemolyticus JCSC1435 Gene: SH0232: mannitol-1-phosphate 5-dehydrogenase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0725: mannitol-1-phosphate 5-dehydrogenase	Macrococcus caseolyticus JCSC5402	mannitol-1-phosphate 5-dehydrogenase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog MtlR - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --