Regulog LexA - Listeriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	LexA
Regulation mode:	repressor
Biological process:	SOS response
Effector:	DNA damage
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 48 sites [see more]

Member of regulog collections

By trascription factor - LexA
By taxonomy - Listeriaceae
By TF family - LexA
By effector - DNA damage
By pathway - SOS response

Statistics of regulated genes
Genome	Genes	Operons
Listeria innocua Clip11262	25	12
Listeria monocytogenes EGD-e	25	12
Listeria seeligeri serovar 1/2b str. SLCC3954	22	10
Listeria welshimeri serovar 6b str. SLCC5334	22	10

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes					Function

CRON 1.
uvrB	* Listeria innocua Clip11262 Site: position = -163 score = 6.10283 sequence = GAATACGAAAATATGTTCGGTTTT Gene: lin2632: Excinuclease ABC, subunit B	* Listeria monocytogenes EGD-e Site: position = -165 score = 6.2522 sequence = AAATGCGAAAATATGTTCGGTTTT Gene: lmo2489: Excinuclease ABC, subunit B	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -165 score = 6.43366 sequence = AAATACGAAAATATGTTCGGTTTT Gene: lse_2389: Excinuclease ABC, subunit B	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -166 score = 6.43366 sequence = AAATACGAAAATATGTTCGGTTTT Gene: lwe2437: Excinuclease ABC, subunit B	Excinuclease ABC, subunit B
uvrA	Listeria innocua Clip11262 Gene: lin2631: Excinuclease ABC, subunit A	Listeria monocytogenes EGD-e Gene: lmo2488: Excinuclease ABC, subunit A	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_2388: Excinuclease ABC, subunit A	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe2436: Excinuclease ABC, subunit A	Excinuclease ABC, subunit A

CRON 2.
recA	* Listeria innocua Clip11262 Site: position = -142 score = 6.30014 sequence = AAATACGAATAAATGTTCGCTTTT Gene: lin1435: DNA recombinase A	* Listeria monocytogenes EGD-e Site: position = -142 score = 6.30014 sequence = AAATACGAATAAATGTTCGCTTTT Gene: lmo1398: DNA recombinase A	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -143 score = 6.30014 sequence = AAATACGAATAAATGTTCGCTTTT Gene: lse_1315: DNA recombinase A	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -143 score = 6.30014 sequence = AAATACGAATAAATGTTCGCTTTT Gene: lwe1414: DNA recombinase A	DNA recombinase A

CRON 3.
lexA	* Listeria innocua Clip11262 Site: position = -144 score = 6.0385 sequence = AAAAAAGAATGTACGTTCGCTTTT Site: position = -84 score = 5.60417 sequence = AAAAACGAACCTTTGTTTGCATAT Gene: lin1340: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Listeria monocytogenes EGD-e Site: position = -144 score = 5.91372 sequence = CAAAAAGAATGTATGTTCGCTTTT Site: position = -84 score = 5.60417 sequence = AAAAACGAACCTTTGTTTGCATAT Gene: lmo1302: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -83 score = 5.60417 sequence = AAAAACGAACCTTTGTTTGCATAT Site: position = -142 score = 5.67401 sequence = CCAAAAGAATGTATGTTCGCTTTT Gene: lse_1219: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -84 score = 5.60417 sequence = AAAAACGAACCTTTGTTTGCATAT Site: position = -146 score = 5.91372 sequence = CAAAAAGAATGTATGTTCGCTTTT Gene: lwe1317: SOS-response repressor and protease LexA (EC 3.4.21.88)	SOS-response repressor and protease LexA (EC 3.4.21.88)
guaA	Listeria innocua Clip11262 Gene: lin1339: Probable GMP synthase	Listeria monocytogenes EGD-e Gene: lmo1301: Probable GMP synthase	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_1218: Probable GMP synthase	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe1316: Probable GMP synthase	Probable GMP synthase

CRON 4.
yhaO	* Listeria innocua Clip11262 Site: position = -42 score = 5.89468 sequence = TAATAAGAACGTATATTCGGTTTT Gene: lin2325: Predicted DNA double-strand break repair protein	* Listeria monocytogenes EGD-e Site: position = -41 score = 5.89468 sequence = TAATAAGAACGTATATTCGGTTTT Gene: lmo2222: Predicted DNA double-strand break repair protein	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -44 score = 5.89468 sequence = TAATAAGAACGTATATTCGGTTTT Gene: lse_2202: Predicted DNA double-strand break repair protein	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -39 score = 5.89468 sequence = TAATAAGAACGTATATTCGGTTTT Gene: lwe2239: Predicted DNA double-strand break repair protein	Predicted DNA double-strand break repair protein
yhaN	Listeria innocua Clip11262 Gene: lin2324: Putative DNA double-strand break repair ATPase	Listeria monocytogenes EGD-e Gene: lmo2221: Putative DNA double-strand break repair ATPase	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_2201: Putative DNA double-strand break repair ATPase	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe2238: Putative DNA double-strand break repair ATPase	Putative DNA double-strand break repair ATPase
yhaM	Listeria innocua Clip11262 Gene: lin2323: Predicted 3'-5' exoribonuclease	Listeria monocytogenes EGD-e Gene: lmo2220: Predicted 3'-5' exoribonuclease	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_2200: Predicted 3'-5' exoribonuclease	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe2237: Predicted 3'-5' exoribonuclease	Predicted 3'-5' exoribonuclease

CRON 5.
pcrA	* Listeria innocua Clip11262 Site: position = -44 score = 5.83983 sequence = AAATAAGAACAAATGTTTGTATGG Gene: lin1871: ATP-dependent DNA helicase UvrD/PcrA	* Listeria monocytogenes EGD-e Site: position = -44 score = 5.83983 sequence = AAATAAGAACAAATGTTTGTATGG Gene: lmo1759: ATP-dependent DNA helicase UvrD/PcrA	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -44 score = 5.83983 sequence = AAATAAGAACAAATGTTTGTATGG Gene: lse_1731: ATP-dependent DNA helicase UvrD/PcrA	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -38 score = 5.83983 sequence = AAATAAGAACAAATGTTTGTATGG Gene: lwe1776: ATP-dependent DNA helicase UvrD/PcrA	ATP-dependent DNA helicase UvrD/PcrA
ligA	Listeria innocua Clip11262 Gene: lin1870: DNA ligase (EC 6.5.1.2)	Listeria monocytogenes EGD-e Gene: lmo1758: DNA ligase (EC 6.5.1.2)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_1730: DNA ligase (EC 6.5.1.2)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe1775: DNA ligase (EC 6.5.1.2)	DNA ligase (EC 6.5.1.2)
yerH	Listeria innocua Clip11262 Gene: lin1869: Putative lipoprotein	Listeria monocytogenes EGD-e Gene: lmo1757: Putative lipoprotein	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_1729: Putative lipoprotein	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe1774: Putative lipoprotein	Putative lipoprotein

CRON 6.
dnaE	* Listeria innocua Clip11262 Site: position = -75 score = 5.63719 sequence = AAACGCGAACACACTTTCTTTTTT Gene: lin1609: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Listeria monocytogenes EGD-e Site: position = -75 score = 5.81865 sequence = AAACACGAACACACTTTCTTTTTT Gene: lmo1574: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -75 score = 5.81865 sequence = AAACACGAACACACTTTCTTTTTT Gene: lse_1489: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -75 score = 5.81865 sequence = AAACACGAACACACTTTCTTTTTT Gene: lwe1587: DNA polymerase III alpha subunit (EC 2.7.7.7)	DNA polymerase III alpha subunit (EC 2.7.7.7)

CRON 7.
addB	* Listeria innocua Clip11262 Site: position = -30 score = 5.75957 sequence = AAATAAAAACATATGTTCGGTGGT Gene: lin2369: ATP-dependent nuclease, subunit B	* Listeria monocytogenes EGD-e Site: position = -30 score = 5.75957 sequence = AAATAAAAACATATGTTCGGTGGT Gene: lmo2268: ATP-dependent nuclease, subunit B	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -30 score = 5.60011 sequence = AAATAAAAACGTATGTTCGGTGGT Gene: lse_2247: ATP-dependent nuclease, subunit B	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -30 score = 5.75957 sequence = AAATAAAAACATATGTTCGGTGGT Gene: lwe2283: ATP-dependent nuclease, subunit B	ATP-dependent nuclease, subunit B
addA	Listeria innocua Clip11262 Gene: lin2368: ATP-dependent nuclease, subunit A	Listeria monocytogenes EGD-e Gene: lmo2267: ATP-dependent nuclease, subunit A	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_2246: ATP-dependent nuclease, subunit A	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe2282: ATP-dependent nuclease, subunit A	ATP-dependent nuclease, subunit A
yisK	Listeria innocua Clip11262 Gene: lin2367: Conserved hypothetical protein	Listeria monocytogenes EGD-e Gene: lmo2266: Conserved hypothetical protein	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_2245: Conserved hypothetical protein	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe2281: Conserved hypothetical protein	Conserved hypothetical protein
PF07457	Listeria innocua Clip11262 Gene: lin2366: Conserved hypothetical protein	Listeria monocytogenes EGD-e Gene: lmo2265: Conserved hypothetical protein	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_2244: Conserved hypothetical protein	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe2280: Conserved hypothetical protein	Conserved hypothetical protein

CRON 8.
lmo2675	* Listeria innocua Clip11262 Site: position = -73 score = 5.52472 sequence = AAACAAGAACGTTTGTTCGTATAA Gene: lin2822: Conserved hypothetical protein	* Listeria monocytogenes EGD-e Site: position = -72 score = 5.63547 sequence = TAATAAGAACATTTGTTCGTATAA Gene: lmo2675: Conserved hypothetical protein	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -72 score = 5.24049 sequence = CAACAAGAACATTCGTTCGTATAA Gene: lse_2581: Conserved hypothetical protein	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -72 score = 5.09735 sequence = AAAATAGAACGCTTGTTCGTATAA Gene: lwe2624: Conserved hypothetical protein	Conserved hypothetical protein
uvrX	Listeria innocua Clip11262 Gene: lin2823: Predicted UV-damage repair protein UvrX	Listeria monocytogenes EGD-e Gene: lmo2676: Predicted UV-damage repair protein UvrX	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_2582: Predicted UV-damage repair protein UvrX	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe2625: Predicted UV-damage repair protein UvrX	Predicted UV-damage repair protein UvrX

CRON 9.
dinP	* Listeria innocua Clip11262 Site: position = -38 score = 5.52928 sequence = GAATAAGAACGCTTGTTCGTTTTA Gene: lin2082: DNA polymerase IV (EC 2.7.7.7)	* Listeria monocytogenes EGD-e Site: position = -38 score = 5.5507 sequence = GAATAAGAACGCTTGTTCGTTTTG Gene: lmo1975: DNA polymerase IV (EC 2.7.7.7)	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -39 score = 5.51056 sequence = ATTAAGGAACATTTGTTCGTTTTT Gene: lse_1955: DNA polymerase IV (EC 2.7.7.7)	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -41 score = 5.25201 sequence = GATTAAGAACGTTTGTTCGATTTT Gene: lwe1994: DNA polymerase IV (EC 2.7.7.7)	DNA polymerase IV (EC 2.7.7.7)

CRON 10.
srmB	* Listeria innocua Clip11262 Site: position = -57 score = 4.67387 sequence = TGATGCGAACGTAGGTTCTGTGTT Gene: lin0195: DinG family ATP-dependent helicase CPE1197	* Listeria monocytogenes EGD-e Site: position = -57 score = 4.25077 sequence = TGTTGCGAACGTAGGTTCTGTGTT Gene: lmo0157: DinG family ATP-dependent helicase CPE1197	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0136: DinG family ATP-dependent helicase CPE1197	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0133: DinG family ATP-dependent helicase CPE1197	DinG family ATP-dependent helicase CPE1197
yxeH	Listeria innocua Clip11262 Gene: lin0196: Cof-like hydrolase	Listeria monocytogenes EGD-e Gene: lmo0158: Cof-like hydrolase	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0137: Cof-like hydrolase	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0134: Cof-like hydrolase	Cof-like hydrolase

CRON 11.
lin1681	* Listeria innocua Clip11262 Site: position = -47 score = 4.64164 sequence = AAAAGGGAACGTATGTTTTATGAT Gene: lin1681: Conserved hypothetical protein	* Listeria monocytogenes EGD-e Site: position = -47 score = 4.93443 sequence = AAAACAGAACATATGTTTTATCAT Gene: lmo1640: Conserved hypothetical protein	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -47 score = 4.72754 sequence = AAAATAGAACGTATGTTTTATGAT Gene: lse_1561: Conserved hypothetical protein	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -47 score = 5.14336 sequence = AAAACAGAACATATGTTTTATGAT Gene: lwe1656: Conserved hypothetical protein	Conserved hypothetical protein
tag	Listeria innocua Clip11262 Gene: lin1680: DNA-3-methyladenine glycosylase (EC 3.2.2.20)	Listeria monocytogenes EGD-e Gene: lmo1639: DNA-3-methyladenine glycosylase (EC 3.2.2.20)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_1560: DNA-3-methyladenine glycosylase (EC 3.2.2.20)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe1655: DNA-3-methyladenine glycosylase (EC 3.2.2.20)	DNA-3-methyladenine glycosylase (EC 3.2.2.20)
lin1679	Listeria innocua Clip11262 Gene: lin1679: Putative carboxypeptidase	Listeria monocytogenes EGD-e Gene: lmo1638: Putative carboxypeptidase	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_1559: Putative carboxypeptidase	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe1654: Putative carboxypeptidase	Putative carboxypeptidase

CRON 12.
int	* Listeria innocua Clip11262 Site: position = -33 score = 4.63328 sequence = AAAAAAGAACGTATGTGCGAAAGG Gene: lin2426: Integrase	* Listeria monocytogenes EGD-e Site: position = -33 score = 4.63328 sequence = AAAAAAGAACGTATGTGCGAAAGG Gene: lmo2332: Integrase	Listeria seeligeri serovar 1/2b str. SLCC3954	Listeria welshimeri serovar 6b str. SLCC5334	Integrase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LexA - Listeriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --