Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog MetR - Alteromonadales

Properties
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode:
Biological process: Methionine biosynthesis
Effector: Homocysteine
Phylum: Proteobacteria/Gamma
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 15 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Pseudoalteromonas atlantica T6c
Alteromonas macleodii 'Deep ecotype'
Glaciecola sp. HTCC2999
Colwellia psychrerythraea 34H 2 2
Alteromonadales bacterium TW-7 6 4
Pseudoalteromonas haloplanktis TAC125 6 4
Pseudoalteromonas tunicata D2 3 3
Idiomarina baltica OS145
Idiomarina loihiensis L2TR
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
glyA
 
Pseudoalteromonas atlantica T6c

Gene: Patl_1299: Serine hydroxymethyltransferase (EC 2.1.2.1)
 
Alteromonas macleodii 'Deep ecotype'

Gene: MADE_02987: Serine hydroxymethyltransferase (EC 2.1.2.1)
 
Glaciecola sp. HTCC2999

Gene: GHTCC_010100009150: Serine hydroxymethyltransferase (EC 2.1.2.1)
*3
Colwellia psychrerythraea 34H

Gene: CPS_0728: Serine hydroxymethyltransferase (EC 2.1.2.1)

Site:
position = -346
score = 5.04122
sequence = AGTGAAAAAAATTCATG

Gene: CPS_4031: Serine hydroxymethyltransferase (EC 2.1.2.1)

Gene: CPS_2477: Serine hydroxymethyltransferase (EC 2.1.2.1)
*
Alteromonadales bacterium TW-7

Site:
position = -119
score = 4.68371
sequence = TGTGAAATAGTTTCAAT

Gene: ATW7_11040: Serine hydroxymethyltransferase (EC 2.1.2.1)
*
Pseudoalteromonas haloplanktis TAC125

Site:
position = -120
score = 4.81971
sequence = TGTGAAATAAATTCAAT

Gene: PSHAa2376: Serine hydroxymethyltransferase (EC 2.1.2.1)
*
Pseudoalteromonas tunicata D2

Site:
position = -133
score = 5.03747
sequence = TGTGAAATTTTTTCAAT

Gene: PTD2_09219: Serine hydroxymethyltransferase (EC 2.1.2.1)
 
Idiomarina baltica OS145

Gene: OS145_10070: Serine hydroxymethyltransferase (EC 2.1.2.1)
 
Idiomarina loihiensis L2TR

Gene: IL1872: Serine hydroxymethyltransferase (EC 2.1.2.1)
Serine hydroxymethyltransferase (EC 2.1.2.1)
 
CRON 2.
metA
 
Pseudoalteromonas atlantica T6c

Gene: Patl_3021: Homoserine O-succinyltransferase (EC 2.3.1.46)
 
Alteromonas macleodii 'Deep ecotype'

Gene: MADE_02861: Homoserine O-succinyltransferase (EC 2.3.1.46)
 
Glaciecola sp. HTCC2999

Gene: GHTCC_010100000045: Homoserine O-succinyltransferase (EC 2.3.1.46)
 
Colwellia psychrerythraea 34H

Gene: CPS_1100: Homoserine O-succinyltransferase (EC 2.3.1.46)
*
Alteromonadales bacterium TW-7

Site:
position = -100
score = 5.18874
sequence = AATGAATAAATTTCATT

Gene: ATW7_10333: Homoserine O-succinyltransferase (EC 2.3.1.46)
*
Pseudoalteromonas haloplanktis TAC125

Site:
position = -108
score = 4.90896
sequence = GATGAAAAAAATTCATT

Gene: PSHAa2224: Homoserine O-succinyltransferase (EC 2.3.1.46)
 
Pseudoalteromonas tunicata D2

Gene: PTD2_08609: Homoserine O-succinyltransferase (EC 2.3.1.46)
 
Idiomarina baltica OS145
 
Idiomarina loihiensis L2TR
Homoserine O-succinyltransferase (EC 2.3.1.46)
metH2
 
Pseudoalteromonas atlantica T6c
 
Alteromonas macleodii 'Deep ecotype'

Gene: MADE_02860: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Glaciecola sp. HTCC2999

Gene: GHTCC_010100000040: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Colwellia psychrerythraea 34H
 
Alteromonadales bacterium TW-7

Gene: ATW7_10328: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Pseudoalteromonas haloplanktis TAC125

Gene: PSHAa2223: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Pseudoalteromonas tunicata D2

Gene: PTD2_08614: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Idiomarina baltica OS145
 
Idiomarina loihiensis L2TR
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metH
 
Pseudoalteromonas atlantica T6c
 
Alteromonas macleodii 'Deep ecotype'

Gene: MADE_02859: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Glaciecola sp. HTCC2999

Gene: GHTCC_010100000035: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Colwellia psychrerythraea 34H

Gene: CPS_1101: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Alteromonadales bacterium TW-7

Gene: ATW7_10323: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Pseudoalteromonas haloplanktis TAC125

Gene: PSHAa2222: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Pseudoalteromonas tunicata D2

Gene: PTD2_08619: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Idiomarina baltica OS145
 
Idiomarina loihiensis L2TR
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
CRON 3.
metR
 
Pseudoalteromonas atlantica T6c
 
Alteromonas macleodii 'Deep ecotype'
 
Glaciecola sp. HTCC2999
*
Colwellia psychrerythraea 34H

Site:
position = -17
score = 4.54471
sequence = GTTGAAATAAATTAATT

Gene: CPS_4359: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Alteromonadales bacterium TW-7

Site:
position = -17
score = 4.71003
sequence = CATGAGAATTATTAAAG

Gene: ATW7_06703: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Pseudoalteromonas haloplanktis TAC125

Site:
position = -17
score = 4.85381
sequence = CATGAGAATTTTTAAAG

Gene: PSHAa1181: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Pseudoalteromonas tunicata D2

Site:
position = -306
score = 4.32169
sequence = TATGAATTTAATTAACA

Site:
position = -17
score = 4.71003
sequence = CATGAGAATTATTAAAG

Gene: PTD2_22482: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
 
Idiomarina baltica OS145
 
Idiomarina loihiensis L2TR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
 
CRON 4.
metF-II
 
Pseudoalteromonas atlantica T6c
 
Alteromonas macleodii 'Deep ecotype'
 
Glaciecola sp. HTCC2999
 
Colwellia psychrerythraea 34H

Gene: CPS_0276: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)
*
Alteromonadales bacterium TW-7

Site:
position = -88
score = 4.68371
sequence = CTTGAAAAACTTTCACT

Gene: ATW7_04247: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)
*
Pseudoalteromonas haloplanktis TAC125

Site:
position = -91
score = 4.83124
sequence = ATTGAAAAACTTTCATT

Gene: PSHAa0642: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)
*
Pseudoalteromonas tunicata D2

Site:
position = -89
score = 4.43179
sequence = GATGAAAAACTTTCACT

Site:
position = -109
score = 4.88111
sequence = AATGAAAAAAATTCAAC

Gene: PTD2_08889: 5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)
 
Idiomarina baltica OS145
 
Idiomarina loihiensis L2TR
5,10-methylenetetrahydrofolate reductase, non-orthologous isozyme (EC 1.5.1.20)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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