Regulog HisR - Clostridia-3
| Regulator type: | Transcription factor |
| Regulator family: | TrpR |
| Regulation mode: | repressor |
| Biological process: | Histidine biosynthesis |
| Effector: | Histidine |
| Phylum: | Firmicutes |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Clostridia-3
- By trascription factor - HisR
- By TF family - TrpR
- By effector - Histidine
- By pathway - Histidine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Bacteroides pectinophilus ATCC 43243 | 1 | 1 |
| Blautia hansenii DSM 20583 | 4 | 2 |
| Bryantella formatexigens DSM 14469 | 3 | 1 |
| Clostridiales bacterium 1_7_47_FAA | 10 | 3 |
| Clostridium bolteae ATCC BAA-613 | 10 | 3 |
| Clostridium nexile DSM 1787 | 9 | 3 |
| Clostridium scindens ATCC 35704 | 9 | 3 |
| Dorea formicigenerans ATCC 27755 | 9 | 3 |
| Dorea longicatena DSM 13814 | 10 | 3 |
| Eubacterium eligens ATCC 27750 | 8 | 3 |
| Eubacterium rectale ATCC 33656 | 9 | 3 |
| Roseburia intestinalis L1-82 | 3 | 2 |
| Ruminococcus gnavus ATCC 29149 | 9 | 3 |
| Ruminococcus lactaris ATCC 29176 | 9 | 3 |
| Genes | Function | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | |||||||||||||||
| hisZ |
*
Bacteroides pectinophilus ATCC 43243 Site: position = -41 score = 5.47703 sequence = CACGTTACCACGCTAAAGTG Gene: BACPEC_00055: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
|
*
Bryantella formatexigens DSM 14469 Site: position = -109 score = 5.09212 sequence = CACGGTACCACGCTAAAGTG Gene: BRYFOR_02963: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Clostridiales bacterium 1_7_47_FAA Site: position = -65 score = 5.07306 sequence = CACTTTACTACGAAAAAGTG Gene: Cbac1_010100026804: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Clostridium bolteae ATCC BAA-613 Site: position = -63 score = 4.79204 sequence = CACTTTACCATAGAAAAGCA Gene: CLOBOL_03939: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Clostridium nexile DSM 1787 Site: position = -40 score = 4.42194 sequence = TATTTTAATATGGTAGCGTA Site: position = -32 score = 4.5711 sequence = TATGGTAGCGTAATAAAGTA Gene: CLONEX_02879: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Clostridium scindens ATCC 35704 Site: position = -47 score = 5.13184 sequence = CATGGTAGCACACTAAAGTG Gene: CLOSCI_00467: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Dorea formicigenerans ATCC 27755 Site: position = -35 score = 5.01336 sequence = TATGGTAGCACGCTAAAGTG Gene: DORFOR_01586: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Dorea longicatena DSM 13814 Site: position = -50 score = 4.97089 sequence = CATGGTAGCACACTAAAGTA Gene: DORLON_00474: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Eubacterium eligens ATCC 27750 Site: position = -47 score = 4.44689 sequence = CACTTCAACGCATTAAAGCA Gene: EUBELI_01024: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Eubacterium rectale ATCC 33656 Site: position = 23 score = 4.64842 sequence = CACTTTACTACAAGAAAGCG Gene: EUBREC_1685: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Roseburia intestinalis L1-82 Site: position = -89 score = 5.0601 sequence = CAAGGTAGCACACTAAAGTG Gene: ROSINTL182_03943: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Ruminococcus gnavus ATCC 29149 Site: position = -37 score = 5.07438 sequence = TGTATTAGCATAGTAAAGTG Gene: RUMGNA_02473: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
*
Ruminococcus lactaris ATCC 29176 Site: position = -40 score = 4.85221 sequence = CGTATTAGCAGACTAAAGTG Gene: RUMLAC_00416: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) |
| hisG |
|
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Gene: BRYFOR_02964: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: Cbac1_010100026809: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: CLOBOL_03938: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: CLONEX_02878: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: CLOSCI_00468: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: DORFOR_01585: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: DORLON_00475: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: EUBELI_01023: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: EUBREC_1686: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: ROSINTL182_03944: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: RUMGNA_02472: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
Gene: RUMLAC_00417: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) |
| hisD |
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Gene: BRYFOR_02965: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: Cbac1_010100026814: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: CLOBOL_03937: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: CLONEX_02877: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: CLOSCI_00469: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: DORFOR_01584: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: DORLON_00476: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: EUBELI_01022: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: EUBREC_1687: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: ROSINTL182_00076: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: RUMGNA_02471: Histidinol dehydrogenase (EC 1.1.1.23) |
Gene: RUMLAC_00418: Histidinol dehydrogenase (EC 1.1.1.23) |
Histidinol dehydrogenase (EC 1.1.1.23) |
| DORLON_00477 |
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Gene: DORLON_00477: hypothetical protein |
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hypothetical protein |
| hisB |
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Gene: Cbac1_010100026819: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: CLOBOL_03936: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: CLONEX_02876: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: CLOSCI_00470: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: DORFOR_01583: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: DORLON_00478: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: EUBELI_01021: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: EUBREC_1688: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: ROSINTL182_00075: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: RUMGNA_02470: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Gene: RUMLAC_00419: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) |
| hisIE |
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Gene: CLOBOL_03934: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
Gene: CLONEX_02875: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
Gene: CLOSCI_00471: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
Gene: DORFOR_01582: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
Gene: DORLON_00479: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
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Gene: EUBREC_1689: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
Gene: ROSINTL182_00074: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
Gene: RUMGNA_02469: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
Gene: RUMLAC_00420: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) |
| Cbac1_010100026824 |
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Gene: Cbac1_010100026824: hypothetical protein |
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hypothetical protein |
| hisA |
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Gene: Cbac1_010100026829: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) |
Gene: CLOBOL_03935: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) |
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Gene: EUBELI_01020: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) |
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Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) |
| CRON 2. | |||||||||||||||
| hisX |
Gene: BACPEC_00692: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Blautia hansenii DSM 20583 Site: position = -61 score = 4.43487 sequence = CAATTTAGCATAGTAGAGAA Gene: BLAHAN_01245: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
Gene: BRYFOR_01357: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Clostridiales bacterium 1_7_47_FAA Site: position = -59 score = 5.59425 sequence = CACTTTAGTGTGCTAATATG Gene: Cbac1_010100022442: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Clostridium bolteae ATCC BAA-613 Site: position = -25 score = 5.26759 sequence = CGCTTTAGTGTGCTAATATG Gene: CLOBOL_01668: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Clostridium nexile DSM 1787 Site: position = -54 score = 4.82891 sequence = TAATTTAGTGTGGTAGAGTA Gene: CLONEX_03079: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Clostridium scindens ATCC 35704 Site: position = -91 score = 5.59682 sequence = CAATTTAGCGTGGTAAAGTA Gene: CLOSCI_00784: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Dorea formicigenerans ATCC 27755 Site: position = -154 score = 5.27016 sequence = CGATTTAGCGTGGTAAAGTA Gene: DORFOR_00662: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Dorea longicatena DSM 13814 Site: position = -94 score = 5.22472 sequence = GATTTTAGTGTGATAAAGTA Gene: DORLON_00748: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Eubacterium eligens ATCC 27750 Site: position = -44 score = 5.10408 sequence = TGATTTACTGTGGTAAAGTG Gene: EUBELI_01397: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Eubacterium rectale ATCC 33656 Site: position = -83 score = 5.16519 sequence = TACTTTAGCGTGATAATTTG Gene: EUBREC_2005: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
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*
Ruminococcus gnavus ATCC 29149 Site: position = -64 score = 5.52734 sequence = CAGTTTAGTATAGTAAAGTG Gene: RUMGNA_00302: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
*
Ruminococcus lactaris ATCC 29176 Site: position = -70 score = 4.59371 sequence = GACTTTACCATGGTGCAGTG Gene: RUMLAC_01337: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
| hisY |
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Gene: BLAHAN_01244: Histidine ABC transporter, permease protein |
Gene: BRYFOR_01358: Histidine ABC transporter, permease protein |
Gene: Cbac1_010100022447: Histidine ABC transporter, permease protein |
Gene: CLOBOL_01669: Histidine ABC transporter, permease protein |
Gene: CLONEX_03078: Histidine ABC transporter, permease protein |
Gene: CLOSCI_00783: Histidine ABC transporter, permease protein |
Gene: DORFOR_00661: Histidine ABC transporter, permease protein |
Gene: DORLON_00747: Histidine ABC transporter, permease protein |
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Gene: EUBREC_2004: Histidine ABC transporter, permease protein |
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Gene: RUMGNA_00303: Histidine ABC transporter, permease protein |
Gene: RUMLAC_01338: Histidine ABC transporter, permease protein |
Histidine ABC transporter, permease protein |
| hisZ |
Gene: BACPEC_00691: Histidine ABC transporter, ATP-binding protein |
Gene: BLAHAN_01243: Histidine ABC transporter, ATP-binding protein |
Gene: BRYFOR_01359: Histidine ABC transporter, ATP-binding protein |
Gene: Cbac1_010100022452: Histidine ABC transporter, ATP-binding protein |
Gene: CLOBOL_01670: Histidine ABC transporter, ATP-binding protein |
Gene: CLONEX_03077: Histidine ABC transporter, ATP-binding protein |
Gene: CLOSCI_00782: Histidine ABC transporter, ATP-binding protein |
Gene: DORFOR_00660: Histidine ABC transporter, ATP-binding protein |
Gene: DORLON_00746: Histidine ABC transporter, ATP-binding protein |
Gene: EUBELI_01396: Histidine ABC transporter, ATP-binding protein |
Gene: EUBREC_2003: Histidine ABC transporter, ATP-binding protein |
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Gene: RUMGNA_00304: Histidine ABC transporter, ATP-binding protein |
Gene: RUMLAC_01339: Histidine ABC transporter, ATP-binding protein |
Histidine ABC transporter, ATP-binding protein |
| CRON 3. | |||||||||||||||
| hisR |
Gene: BACPEC_00270: Predicted histidine repressor, TrpR family |
*
Blautia hansenii DSM 20583 Site: position = -68 score = 4.63229 sequence = AAATTTACTGTGCTACTATA Gene: BLAHAN_01640: Predicted histidine repressor, TrpR family |
Gene: BRYFOR_00847: Predicted histidine repressor, TrpR family |
*
Clostridiales bacterium 1_7_47_FAA Site: position = -167 score = 5.47036 sequence = AACTTTAATATGTTAAAATG Gene: Cbac1_010100017829: Predicted histidine repressor, TrpR family |
*
Clostridium bolteae ATCC BAA-613 Site: position = -113 score = 5.5397 sequence = GACTTTAATATGCTAAAATG Gene: CLOBOL_07128: Predicted histidine repressor, TrpR family |
*
Clostridium nexile DSM 1787 Site: position = -54 score = 4.98994 sequence = GAGTTTACTGTGCTAAAATA Gene: CLONEX_00021: Predicted histidine repressor, TrpR family |
*
Clostridium scindens ATCC 35704 Site: position = -57 score = 5.44201 sequence = AAATTTAGTGTGTTAAAATG Gene: CLOSCI_02856: Predicted histidine repressor, TrpR family |
*
Dorea formicigenerans ATCC 27755 Site: position = -61 score = 5.31839 sequence = AAATTTACTGTGTTAAAATG Gene: DORFOR_03026: Predicted histidine repressor, TrpR family |
*
Dorea longicatena DSM 13814 Site: position = 24 score = 5.33518 sequence = GAATTTAGTGTGTTAAAATG Gene: DORLON_01427: Predicted histidine repressor, TrpR family |
*
Eubacterium eligens ATCC 27750 Site: position = -68 score = 4.67833 sequence = AACTTCACTGTGTTAAAATT Gene: EUBELI_01562: Predicted histidine repressor, TrpR family |
*
Eubacterium rectale ATCC 33656 Site: position = -37 score = 5.29104 sequence = AACTTTAATATGTTAAAATT Gene: EUBREC_1393: Predicted histidine repressor, TrpR family |
*
Roseburia intestinalis L1-82 Site: position = -75 score = 5.64652 sequence = AACTTTAATATGCTAAAATG Gene: ROSINTL182_04526: Predicted histidine repressor, TrpR family |
*
Ruminococcus gnavus ATCC 29149 Site: position = -58 score = 5.37932 sequence = AAATTTAGTGTGATAAAATG Gene: RUMGNA_03779: Predicted histidine repressor, TrpR family |
*
Ruminococcus lactaris ATCC 29176 Site: position = -59 score = 5.61817 sequence = AAATTTAGTGTGCTAAAATG Gene: RUMLAC_00772: Predicted histidine repressor, TrpR family |
Predicted histidine repressor, TrpR family |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |