Regulog CzcR2 - Lactobacillaceae

Properties
Regulator type:	Transcription factor
Regulator family:	ArsR
Regulation mode:
Biological process:	Zinc resistance; Cobalt resistance; Cadmium resistance
Effector:
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 7 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By trascription factor - CzrA
By TF family - ArsR
By pathway - Zinc resistance
By pathway - Cobalt resistance
By pathway - Cadmium resistance

Statistics of regulated genes
Genome	Genes	Operons
Lactobacillus acidophilus NCFM
Lactobacillus brevis ATCC 367	2	2
Lactobacillus casei ATCC 334
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1
Lactobacillus reuteri JCM 1112
Lactobacillus rhamnosus GG	2	1
Lactobacillus sakei subsp. sakei 23K
Lactobacillus salivarius subsp. salivarius UCC118
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Oenococcus oeni PSU-1
Pediococcus pentosaceus ATCC 25745	2	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
czcX	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112	* Lactobacillus rhamnosus GG Site: position = -68 score = 5.98704 sequence = TTATGTTGACATTAACATAT Gene: LGG_02417: Predicted cobalt-zinc-cadmium resistance protein	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Predicted cobalt-zinc-cadmium resistance protein
czcR2	Lactobacillus acidophilus NCFM	* Lactobacillus brevis ATCC 367 Site: position = -40 score = 5.93834 sequence = ATATGTTATCATATTCATAT Site: position = -56 score = 6.06647 sequence = ATATGTTATTTTCAACATAT Gene: LVIS_0395: Cobalt-zinc-cadmium resistance transcriptional regulator CzcR1, ArsR family	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG Gene: LGG_02418: Cobalt-zinc-cadmium resistance transcriptional regulator CzcR1, ArsR family	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	* Pediococcus pentosaceus ATCC 25745 Site: position = -34 score = 6.06041 sequence = ATATGATAACATATTCATAT Gene: PEPE_0028: Cobalt-zinc-cadmium resistance transcriptional regulator CzcR1, ArsR family	Cobalt-zinc-cadmium resistance transcriptional regulator CzcR1, ArsR family

CRON 2.
cadD2	Lactobacillus acidophilus NCFM	* Lactobacillus brevis ATCC 367 Site: position = 14 score = 6.06647 sequence = ATATGTTGAAAATAACATAT Site: position = -2 score = 5.93834 sequence = ATATGAATATGATAACATAT Gene: LVIS_0396: Predicted permease, cadmium resistance protein	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956 Gene: LAF_0789: Predicted permease, cadmium resistance protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	* Pediococcus pentosaceus ATCC 25745 Site: position = -51 score = 6.06041 sequence = ATATGAATATGTTATCATAT Gene: PEPE_0029: Predicted permease, cadmium resistance protein	Predicted permease, cadmium resistance protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog CzcR2 - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --