Regulog LexA - Lactobacillaceae

Properties
Regulator type:	Transcription factor
Regulator family:	LexA
Regulation mode:	repressor
Biological process:	SOS response
Effector:	DNA damage
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 99 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By trascription factor - LexA
By TF family - LexA
By effector - DNA damage
By pathway - SOS response

Statistics of regulated genes
Genome	Genes	Operons
Lactobacillus acidophilus NCFM	7	4
Lactobacillus brevis ATCC 367	15	8
Lactobacillus casei ATCC 334	12	9
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	5	4
Lactobacillus fermentum IFO 3956	8	5
Lactobacillus helveticus DPC 4571	8	5
Lactobacillus johnsonii NCC 533	5	4
Lactobacillus plantarum WCFS1	17	9
Lactobacillus reuteri JCM 1112	10	6
Lactobacillus rhamnosus GG	14	9
Lactobacillus sakei subsp. sakei 23K	8	6
Lactobacillus salivarius subsp. salivarius UCC118	2	2
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	14	8
Oenococcus oeni PSU-1	9	6
Pediococcus pentosaceus ATCC 25745	8	6

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
dnaE	Lactobacillus acidophilus NCFM Gene: LBA0955: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Lactobacillus brevis ATCC 367 Site: position = -86 score = 4.7212 sequence = ACGAACATTTGTTCAT Gene: LVIS_0763: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus casei ATCC 334 Gene: LSEI_1363: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0760: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus fermentum IFO 3956 Gene: LAF_0867: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus helveticus DPC 4571 Gene: lhv_1048: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus johnsonii NCC 533 Gene: LJ1077: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Lactobacillus plantarum WCFS1 Site: position = -191 score = 4.28035 sequence = TAGAACAACTGTTTGG Gene: lp_1899: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus reuteri JCM 1112 Gene: LAR_0721: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus rhamnosus GG Gene: LGG_01373: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus sakei subsp. sakei 23K Gene: LSA1034: DNA polymerase III alpha subunit (EC 2.7.7.7)	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_0865: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -29 score = 4.52531 sequence = GAAAACGGATGTTCGT Gene: LEUM_0774: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Oenococcus oeni PSU-1 Site: position = -45 score = 4.98337 sequence = GCGAACATACTTTCGT Gene: OEOE_1000: DNA polymerase III alpha subunit (EC 2.7.7.7)	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1094: DNA polymerase III alpha subunit (EC 2.7.7.7)	DNA polymerase III alpha subunit (EC 2.7.7.7)

CRON 2.
addB	* Lactobacillus acidophilus NCFM Site: position = -8 score = 4.05086 sequence = GCGAACAAATGATCAA Gene: LBA1166: ATP-dependent nuclease, subunit B	* Lactobacillus brevis ATCC 367 Site: position = -202 score = 4.44626 sequence = TTGAACGTGTGTTCGT Gene: LVIS_2268: ATP-dependent nuclease, subunit B	Lactobacillus casei ATCC 334 Gene: LSEI_1490: ATP-dependent nuclease, subunit B	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0907: ATP-dependent nuclease, subunit B	* Lactobacillus fermentum IFO 3956 Site: position = -75 score = 4.13981 sequence = GCGAACATTCATTCCC Gene: LAF_0036: ATP-dependent nuclease, subunit B	* Lactobacillus helveticus DPC 4571 Site: position = -8 score = 4.05086 sequence = GCGAACAAATGATCAA Gene: lhv_1274: ATP-dependent nuclease, subunit B	Lactobacillus johnsonii NCC 533 Gene: LJ1204: ATP-dependent nuclease, subunit B	* Lactobacillus plantarum WCFS1 Site: position = -32 score = 4.33099 sequence = GAGAACGTTTGTTCAG Gene: lp_2694: ATP-dependent nuclease, subunit B	* Lactobacillus reuteri JCM 1112 Site: position = -67 score = 4.75461 sequence = AAGAATATATGTTCGT Gene: LAR_0047: ATP-dependent nuclease, subunit B	Lactobacillus rhamnosus GG Gene: LGG_01497: ATP-dependent nuclease, subunit B	Lactobacillus sakei subsp. sakei 23K Gene: LSA0909: ATP-dependent nuclease, subunit B	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1608: ATP-dependent nuclease, subunit B	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1482: ATP-dependent nuclease, subunit B	Oenococcus oeni PSU-1 Gene: OEOE_0308: ATP-dependent nuclease, subunit B	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1833: ATP-dependent nuclease, subunit B	ATP-dependent nuclease, subunit B
addA	Lactobacillus acidophilus NCFM Gene: LBA1165: ATP-dependent nuclease, subunit A	Lactobacillus brevis ATCC 367 Gene: LVIS_2267: ATP-dependent nuclease, subunit A	Lactobacillus casei ATCC 334 Gene: LSEI_1489: ATP-dependent nuclease, subunit A	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0908: ATP-dependent nuclease, subunit A	Lactobacillus fermentum IFO 3956 Gene: LAF_0037: ATP-dependent nuclease, subunit A	Lactobacillus helveticus DPC 4571 Gene: lhv_1273: ATP-dependent nuclease, subunit A	Lactobacillus johnsonii NCC 533 Gene: LJ1203: ATP-dependent nuclease, subunit A	Lactobacillus plantarum WCFS1 Gene: lp_2693: ATP-dependent nuclease, subunit A	Lactobacillus reuteri JCM 1112 Gene: LAR_0048: ATP-dependent nuclease, subunit A	Lactobacillus rhamnosus GG Gene: LGG_01496: ATP-dependent nuclease, subunit A	2 Lactobacillus sakei subsp. sakei 23K Gene: LSA0910: ATP-dependent nuclease, subunit A Gene: LSA0911: ATP-dependent nuclease, subunit A	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1607: ATP-dependent nuclease, subunit A	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1481: ATP-dependent nuclease, subunit A	Oenococcus oeni PSU-1 Gene: OEOE_0309: ATP-dependent nuclease, subunit A	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1832: ATP-dependent nuclease, subunit A	ATP-dependent nuclease, subunit A
dinG	Lactobacillus acidophilus NCFM Gene: LBA1164: DinG family ATP-dependent helicase	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334 Gene: LSEI_1488: DinG family ATP-dependent helicase	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0909: DinG family ATP-dependent helicase	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571 Gene: lhv_1272: DinG family ATP-dependent helicase	Lactobacillus johnsonii NCC 533 Gene: LJ1202: DinG family ATP-dependent helicase	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG Gene: LGG_01495: DinG family ATP-dependent helicase	Lactobacillus sakei subsp. sakei 23K Gene: LSA0912: DinG family ATP-dependent helicase	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_0686: DinG family ATP-dependent helicase	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	DinG family ATP-dependent helicase
LEUM_1483	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -62 score = 4.2747 sequence = ACGAACAATCGTGCGC Gene: LEUM_1483: Predicted esterase	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Predicted esterase

CRON 3.
uvrC	Lactobacillus acidophilus NCFM Gene: LBA0946: Nuclease subunit of the excinuclease complex	* Lactobacillus brevis ATCC 367 Site: position = -64 score = 4.41145 sequence = CCAAACAAACATTCGG Gene: LVIS_1383: Nuclease subunit of the excinuclease complex	* Lactobacillus casei ATCC 334 Site: position = -29 score = 4.89813 sequence = GCGAACATTTGTTTTA Gene: LSEI_1346: Nuclease subunit of the excinuclease complex	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0746: Nuclease subunit of the excinuclease complex	Lactobacillus fermentum IFO 3956 Gene: LAF_0625: Nuclease subunit of the excinuclease complex	Lactobacillus helveticus DPC 4571 Gene: lhv_1040: Nuclease subunit of the excinuclease complex	Lactobacillus johnsonii NCC 533 Gene: LJ1070: Nuclease subunit of the excinuclease complex	Lactobacillus plantarum WCFS1 Gene: lp_2109: Nuclease subunit of the excinuclease complex	Lactobacillus reuteri JCM 1112 Gene: LAR_0634: Nuclease subunit of the excinuclease complex	* Lactobacillus rhamnosus GG Site: position = -29 score = 4.89813 sequence = GCGAACATTTGTTTTA Gene: LGG_01358: Nuclease subunit of the excinuclease complex	* Lactobacillus sakei subsp. sakei 23K Site: position = -35 score = 4.3607 sequence = ACGAACACTTGTTTTG Gene: LSA1055: Nuclease subunit of the excinuclease complex	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1098: Nuclease subunit of the excinuclease complex	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0520: Nuclease subunit of the excinuclease complex	Oenococcus oeni PSU-1 Gene: OEOE_1073: Nuclease subunit of the excinuclease complex	* Pediococcus pentosaceus ATCC 25745 Site: position = 16 score = 3.8551 sequence = TTGAACATAAGTTGGC Gene: PEPE_1135: Nuclease subunit of the excinuclease complex	Nuclease subunit of the excinuclease complex

CRON 4.
srmB	Lactobacillus acidophilus NCFM	* Lactobacillus brevis ATCC 367 Site: position = -70 score = 4.06559 sequence = TCGAACACGCGTTCAA Gene: LVIS_1870: DinG family ATP-dependent helicase	* Lactobacillus casei ATCC 334 Site: position = -55 score = 4.4734 sequence = GAGAATGTATGTTCTA Gene: LSEI_0288: DinG family ATP-dependent helicase	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -52 score = 4.5697 sequence = ACGAACAGATGTTTTA Gene: lp_0308: DinG family ATP-dependent helicase	Lactobacillus reuteri JCM 1112	* Lactobacillus rhamnosus GG Site: position = -55 score = 4.32832 sequence = CAGAATGTATGTTCTA Gene: LGG_00328: DinG family ATP-dependent helicase	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_0349: DinG family ATP-dependent helicase	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1728: DinG family ATP-dependent helicase	DinG family ATP-dependent helicase
lp_0307	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367 Gene: LVIS_1871: Conserved hypothetical protein	Lactobacillus casei ATCC 334 Gene: LSEI_0287: Conserved hypothetical protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0307: Conserved hypothetical protein	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG Gene: LGG_00327: Conserved hypothetical protein	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Conserved hypothetical protein
lp_0306	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367 Gene: LVIS_1872: Conserved hypothetical protein	Lactobacillus casei ATCC 334 Gene: LSEI_0286: Conserved hypothetical protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0306: Conserved hypothetical protein	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG Gene: LGG_00326: Conserved hypothetical protein	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Conserved hypothetical protein

CRON 5.
recA	* Lactobacillus acidophilus NCFM Site: position = -82 score = 4.16045 sequence = TTGAACATTAGTTTGT Gene: LBA0666: DNA recombinase A	Lactobacillus brevis ATCC 367 Gene: LVIS_1237: DNA recombinase A	2 Lactobacillus casei ATCC 334* Gene: LSEI_0923: DNA recombinase A Site: position = -221 score = 4.82393 sequence = ACAAACGCATGTTCGA Gene: LSEI_2649: DNA recombinase A	* Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Site: position = -84 score = 4.0955 sequence = TTGAACGTTAGTTCGG Gene: LBUL_0535: DNA recombinase A	* Lactobacillus fermentum IFO 3956 Site: position = -89 score = 3.9005 sequence = CCGAACCCCTGTTCGA Gene: LAF_0511: DNA recombinase A	* Lactobacillus helveticus DPC 4571 Site: position = -82 score = 4.07998 sequence = TTGAACGTTAGTTTGT Gene: lhv_0713: DNA recombinase A	Lactobacillus johnsonii NCC 533 Gene: LJ0839: DNA recombinase A	* Lactobacillus plantarum WCFS1 Site: position = -90 score = 4.81157 sequence = ACGAACTTTTGTTCGC Gene: lp_2301: DNA recombinase A	* Lactobacillus reuteri JCM 1112 Site: position = -89 score = 4.31521 sequence = ACGAACTTTTGTTCAC Gene: LAR_0509: DNA recombinase A	2 Lactobacillus rhamnosus GG* Gene: LGG_00889: DNA recombinase A Site: position = -69 score = 4.43742 sequence = ACAAACGCGTGTTCGA Gene: LGG_02643: DNA recombinase A	* Lactobacillus sakei subsp. sakei 23K Site: position = -94 score = 4.89442 sequence = AAGAACGTTTGTTCGA Gene: LSA0487: DNA recombinase A	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1130: DNA recombinase A	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -82 score = 5.2234 sequence = ACGAACAAATGTTCGA Gene: LEUM_0584: DNA recombinase A	* Oenococcus oeni PSU-1 Site: position = -57 score = 5.21756 sequence = ACGAACAAATGTTCGT Gene: OEOE_1382: DNA recombinase A	* Pediococcus pentosaceus ATCC 25745 Site: position = -84 score = 4.81741 sequence = TCGAACTTTTGTTCGC Gene: PEPE_1276: DNA recombinase A	DNA recombinase A

CRON 6.
dinP	Lactobacillus acidophilus NCFM Gene: LBA0414: DNA polymerase IV (EC 2.7.7.7)	* Lactobacillus brevis ATCC 367 Site: position = -49 score = 4.20368 sequence = GCAAACGCCCGTTCGG Gene: LVIS_1226: DNA polymerase IV (EC 2.7.7.7)	Lactobacillus casei ATCC 334 Gene: LSEI_0779: DNA polymerase IV (EC 2.7.7.7)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_1489: DNA polymerase IV (EC 2.7.7.7)	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571 Gene: lhv_0433: DNA polymerase IV (EC 2.7.7.7)	Lactobacillus johnsonii NCC 533 Gene: LJ0471: DNA polymerase IV (EC 2.7.7.7)	* Lactobacillus plantarum WCFS1 Site: position = -85 score = 4.83277 sequence = TTGAACGTATGTTCGT Gene: lp_2280: DNA polymerase IV (EC 2.7.7.7)	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG Gene: LGG_00761: DNA polymerase IV (EC 2.7.7.7)	Lactobacillus sakei subsp. sakei 23K Gene: LSA0382: DNA polymerase IV (EC 2.7.7.7)	Lactobacillus salivarius subsp. salivarius UCC118	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -32 score = 3.90206 sequence = AAGAACACTTGTTCCT Gene: LEUM_1586: DNA polymerase IV (EC 2.7.7.7)	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1266: DNA polymerase IV (EC 2.7.7.7)	DNA polymerase IV (EC 2.7.7.7)
nrnA	Lactobacillus acidophilus NCFM Gene: LBA0415: 3'-to-5' oligoribonuclease A	Lactobacillus brevis ATCC 367 Gene: LVIS_1225: 3'-to-5' oligoribonuclease A	Lactobacillus casei ATCC 334 Gene: LSEI_0781: 3'-to-5' oligoribonuclease A	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_1488: 3'-to-5' oligoribonuclease A	Lactobacillus fermentum IFO 3956 Gene: LAF_0519: 3'-to-5' oligoribonuclease A	Lactobacillus helveticus DPC 4571 Gene: lhv_0434: 3'-to-5' oligoribonuclease A	Lactobacillus johnsonii NCC 533 Gene: LJ0472: 3'-to-5' oligoribonuclease A	Lactobacillus plantarum WCFS1 Gene: lp_2279: 3'-to-5' oligoribonuclease A	Lactobacillus reuteri JCM 1112 Gene: LAR_0517: 3'-to-5' oligoribonuclease A	Lactobacillus rhamnosus GG Gene: LGG_00763: 3'-to-5' oligoribonuclease A	Lactobacillus sakei subsp. sakei 23K Gene: LSA0384: 3'-to-5' oligoribonuclease A	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1585: 3'-to-5' oligoribonuclease A	Oenococcus oeni PSU-1 Gene: OEOE_1286: 3'-to-5' oligoribonuclease A	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1265: 3'-to-5' oligoribonuclease A	3'-to-5' oligoribonuclease A
rheB	Lactobacillus acidophilus NCFM Gene: LBA0416: Putative ATP-dependent DNA/RNA helicase	Lactobacillus brevis ATCC 367 Gene: LVIS_1224: Putative ATP-dependent DNA/RNA helicase	Lactobacillus casei ATCC 334 Gene: LSEI_0782: Putative ATP-dependent DNA/RNA helicase	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_1487: Putative ATP-dependent DNA/RNA helicase	Lactobacillus fermentum IFO 3956 Gene: LAF_0520: Putative ATP-dependent DNA/RNA helicase	Lactobacillus helveticus DPC 4571 Gene: lhv_0435: Putative ATP-dependent DNA/RNA helicase	Lactobacillus johnsonii NCC 533 Gene: LJ0473: Putative ATP-dependent DNA/RNA helicase	Lactobacillus plantarum WCFS1 Gene: lp_2278: Putative ATP-dependent DNA/RNA helicase	Lactobacillus reuteri JCM 1112 Gene: LAR_0518: Putative ATP-dependent DNA/RNA helicase	Lactobacillus rhamnosus GG Gene: LGG_00764: Putative ATP-dependent DNA/RNA helicase	Lactobacillus sakei subsp. sakei 23K Gene: LSA0385: Putative ATP-dependent DNA/RNA helicase	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1584: Putative ATP-dependent DNA/RNA helicase	Oenococcus oeni PSU-1 Gene: OEOE_1285: Putative ATP-dependent DNA/RNA helicase	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1264: Putative ATP-dependent DNA/RNA helicase	Putative ATP-dependent DNA/RNA helicase

CRON 7.
lexA	* Lactobacillus acidophilus NCFM Site: position = -80 score = 4.10272 sequence = AAGAACGCCTGTTTGA Gene: LBA1280: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	Lactobacillus brevis ATCC 367	2 Lactobacillus casei ATCC 334* Site: position = -61 score = 5.02178 sequence = GCAAACGTTCGTTCGC Gene: LSEI_0730: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88) Site: position = -53 score = 4.14189 sequence = TCAAAAGTTTTTTTGT Gene: LSEI_1968: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Site: position = -85 score = 4.06417 sequence = TAGAACGCCCGTTTGC Gene: LBUL_1265: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus fermentum IFO 3956 Site: position = -79 score = 4.88731 sequence = TCGAACGTACGTTTTA Gene: LAF_0708: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus helveticus DPC 4571 Site: position = -82 score = 4.78158 sequence = TAGAACATTCGTTTGA Gene: lhv_1364: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus johnsonii NCC 533 Site: position = -71 score = 4.1388 sequence = AAGAACGCCTGTTTGC Gene: LJ1508: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus plantarum WCFS1 Site: position = -81 score = 5.00156 sequence = CCGAACATTTGTTTGA Gene: lp_2063: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus reuteri JCM 1112 Site: position = -71 score = 5.17189 sequence = GCGAACGTACGTTTGA Gene: LAR_0650: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus rhamnosus GG Site: position = -60 score = 4.69334 sequence = GCAAACGTCCGTTCGT Gene: LGG_00717: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus sakei subsp. sakei 23K Site: position = -70 score = 4.7182 sequence = ACGAACACTTGTTTGA Gene: LSA1275: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -74 score = 4.57633 sequence = ACGAACGTTAGTTTGA Gene: LSL_0540: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -75 score = 5.02424 sequence = ACGAACAAACGTTTGA Gene: LEUM_1204: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Oenococcus oeni PSU-1 Site: position = -76 score = 4.89856 sequence = ACGAACATGTGTTTGT Gene: OEOE_0970: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	* Pediococcus pentosaceus ATCC 25745 Site: position = -68 score = 5.14664 sequence = GCGAACATTTGTTTGA Gene: PEPE_0870: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)	SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88)

CRON 8.
xerC	Lactobacillus acidophilus NCFM Gene: LBA1145: Site-specific DNA-tyrosine recombinase, XerC	* Lactobacillus brevis ATCC 367 Site: position = -112 score = 4.09422 sequence = TAAAACAAATATTTTA Site: position = -27 score = 4.74978 sequence = CAGAACATACGTTTGG Gene: LVIS_0812: Site-specific DNA-tyrosine recombinase, XerC	* Lactobacillus casei ATCC 334 Site: position = -26 score = 5.00386 sequence = GAAAACATACGTTCGA Gene: LSEI_1415: Site-specific DNA-tyrosine recombinase, XerC	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0947: Site-specific DNA-tyrosine recombinase, XerC	Lactobacillus fermentum IFO 3956 Gene: LAF_0940: Site-specific DNA-tyrosine recombinase, XerC	* Lactobacillus helveticus DPC 4571 Site: position = -77 score = 4.86205 sequence = TAAAACATTTGTTCGA Gene: lhv_1253: Site-specific DNA-tyrosine recombinase, XerC	* Lactobacillus johnsonii NCC 533 Site: position = -28 score = 4.66372 sequence = ACAAACCTACGTTCGA Gene: LJ1177: Site-specific DNA-tyrosine recombinase, XerC	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112 Gene: LAR_0930: Site-specific DNA-tyrosine recombinase, XerC	* Lactobacillus rhamnosus GG Site: position = -27 score = 5.08433 sequence = GAAAACATATGTTCGA Gene: LGG_01425: Site-specific DNA-tyrosine recombinase, XerC	Lactobacillus sakei subsp. sakei 23K Gene: LSA0967: Site-specific DNA-tyrosine recombinase, XerC	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -25 score = 4.52045 sequence = TCAAATGAATGTTCGG Gene: LSL_1797: Site-specific DNA-tyrosine recombinase, XerC	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Site-specific DNA-tyrosine recombinase, XerC

CRON 9.
parE	Lactobacillus acidophilus NCFM Gene: LBA1122: Topoisomerase IV subunit B (EC 5.99.1.-)	* Lactobacillus brevis ATCC 367 Site: position = -70 score = 4.72962 sequence = TTGAACATACGTTCGG Gene: LVIS_0804: Topoisomerase IV subunit B (EC 5.99.1.-)	Lactobacillus casei ATCC 334 Gene: LSEI_1408: Topoisomerase IV subunit B (EC 5.99.1.-)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0900: Topoisomerase IV subunit B (EC 5.99.1.-)	Lactobacillus fermentum IFO 3956 Gene: LAF_0903: Topoisomerase IV subunit B (EC 5.99.1.-)	Lactobacillus helveticus DPC 4571 Gene: lhv_1232: Topoisomerase IV subunit B (EC 5.99.1.-)	Lactobacillus johnsonii NCC 533 Gene: LJ1170: Topoisomerase IV subunit B (EC 5.99.1.-)	* Lactobacillus plantarum WCFS1 Site: position = -185 score = 4.90193 sequence = GCGAACGTGTGTTTGC Gene: lp_1840: Topoisomerase IV subunit B (EC 5.99.1.-)	* Lactobacillus reuteri JCM 1112 Site: position = -45 score = 4.61093 sequence = TCGAACATACGTTTAG Gene: LAR_0752: Topoisomerase IV subunit B (EC 5.99.1.-)	* Lactobacillus rhamnosus GG Site: position = -179 score = 4.54197 sequence = ACGAACACACATTCGA Gene: LGG_01419: Topoisomerase IV subunit B (EC 5.99.1.-)	* Lactobacillus sakei subsp. sakei 23K Site: position = -113 score = 4.74273 sequence = GCGAACATACATTTGG Gene: LSA0976: Topoisomerase IV subunit B (EC 5.99.1.-)	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_0871: Topoisomerase IV subunit B (EC 5.99.1.-)	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -36 score = 4.28432 sequence = ACGAACACTGGTTCGT Gene: LEUM_1364: Topoisomerase IV subunit B (EC 5.99.1.-)	* Oenococcus oeni PSU-1 Site: position = -8 score = 4.77837 sequence = ACGAATGAATGTTCGC Gene: OEOE_1026: Topoisomerase IV subunit B (EC 5.99.1.-)	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0959: Topoisomerase IV subunit B (EC 5.99.1.-)	Topoisomerase IV subunit B (EC 5.99.1.-)
parC	Lactobacillus acidophilus NCFM Gene: LBA1123: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus brevis ATCC 367 Gene: LVIS_0805: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus casei ATCC 334 Gene: LSEI_1409: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0901: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus fermentum IFO 3956 Gene: LAF_0904: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus helveticus DPC 4571 Gene: lhv_1233: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus johnsonii NCC 533 Gene: LJ1171: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus plantarum WCFS1 Gene: lp_1839: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus reuteri JCM 1112 Gene: LAR_0753: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus rhamnosus GG Gene: LGG_01420: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus sakei subsp. sakei 23K Gene: LSA0975: Topoisomerase IV subunit A (EC 5.99.1.-)	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_0872: Topoisomerase IV subunit A (EC 5.99.1.-)	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1363: Topoisomerase IV subunit A (EC 5.99.1.-)	Oenococcus oeni PSU-1 Gene: OEOE_1027: Topoisomerase IV subunit A (EC 5.99.1.-)	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0958: Topoisomerase IV subunit A (EC 5.99.1.-)	Topoisomerase IV subunit A (EC 5.99.1.-)

CRON 10.
uvrB	* Lactobacillus acidophilus NCFM Site: position = -87 score = 4.59686 sequence = GCGAAAACACGTTCGT Gene: LBA0688: Excinuclease ABC, subunit B	* Lactobacillus brevis ATCC 367 Site: position = -101 score = 4.88021 sequence = GCGAAAGTATGTTCGG Gene: LVIS_0648: Excinuclease ABC, subunit B	* Lactobacillus casei ATCC 334 Site: position = -127 score = 4.16597 sequence = ACGAAATTTTGTTTGG Site: position = -206 score = 5.02529 sequence = GCGAAAGTATGTTCGC Gene: LSEI_0956: Excinuclease ABC, subunit B	* Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Site: position = -64 score = 4.11058 sequence = TAGAATCTATGTTCGG Gene: LBUL_0549: Excinuclease ABC, subunit B	* Lactobacillus fermentum IFO 3956 Site: position = -99 score = 4.73644 sequence = ACGAATAAACGTTCGT Gene: LAF_0353: Excinuclease ABC, subunit B	* Lactobacillus helveticus DPC 4571 Site: position = -86 score = 4.59686 sequence = GCGAAAACACGTTCGT Gene: lhv_0729: Excinuclease ABC, subunit B	* Lactobacillus johnsonii NCC 533 Site: position = -86 score = 5.02529 sequence = GCGAAAATACGTTCGC Gene: LJ0863: Excinuclease ABC, subunit B	* Lactobacillus plantarum WCFS1 Site: position = -146 score = 4.98921 sequence = GCGAAAGTATGTTCGA Gene: lp_0772: Excinuclease ABC, subunit B	* Lactobacillus reuteri JCM 1112 Site: position = -132 score = 4.39476 sequence = ACGAATACATGTTTGG Gene: LAR_0372: Excinuclease ABC, subunit B	* Lactobacillus rhamnosus GG Site: position = -271 score = 5.02529 sequence = GCGAAAGTATGTTCGC Gene: LGG_00923: Excinuclease ABC, subunit B	* Lactobacillus sakei subsp. sakei 23K Site: position = -190 score = 4.88021 sequence = GCGAAAATACGTTCGG Gene: LSA0523: Excinuclease ABC, subunit B	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1175: Excinuclease ABC, subunit B	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -89 score = 4.89442 sequence = TAGAACGTTTGTTCGT Gene: LEUM_0392: Excinuclease ABC, subunit B	Oenococcus oeni PSU-1 Gene: OEOE_0372: Excinuclease ABC, subunit B	* Pediococcus pentosaceus ATCC 25745 Site: position = -127 score = 4.88021 sequence = GCGAAAGTATGTTCGG Gene: PEPE_0448: Excinuclease ABC, subunit B	Excinuclease ABC, subunit B
OEOE_0373	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1 Gene: OEOE_0373: Short-chain alcohol dehydrogenase	Pediococcus pentosaceus ATCC 25745	Short-chain alcohol dehydrogenase
uvrA	Lactobacillus acidophilus NCFM Gene: LBA0689: Excinuclease ABC, subunit A	Lactobacillus brevis ATCC 367 Gene: LVIS_0649: Excinuclease ABC, subunit A	Lactobacillus casei ATCC 334 Gene: LSEI_0957: Excinuclease ABC, subunit A	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0550: Excinuclease ABC, subunit A	Lactobacillus fermentum IFO 3956 Gene: LAF_0354: Excinuclease ABC, subunit A	Lactobacillus helveticus DPC 4571 Gene: lhv_0730: Excinuclease ABC, subunit A	Lactobacillus johnsonii NCC 533 Gene: LJ0864: Excinuclease ABC, subunit A	Lactobacillus plantarum WCFS1 Gene: lp_0773: Excinuclease ABC, subunit A	Lactobacillus reuteri JCM 1112 Gene: LAR_0373: Excinuclease ABC, subunit A	Lactobacillus rhamnosus GG Gene: LGG_00924: Excinuclease ABC, subunit A	Lactobacillus sakei subsp. sakei 23K Gene: LSA0524: Excinuclease ABC, subunit A	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1174: Excinuclease ABC, subunit A	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0393: Excinuclease ABC, subunit A	* Oenococcus oeni PSU-1 Site: position = -50 score = 4.17301 sequence = GGGAACTAATGTTCGC Gene: OEOE_0374: Excinuclease ABC, subunit A	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0449: Excinuclease ABC, subunit A	Excinuclease ABC, subunit A

CRON 11.
umuC	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	* Lactobacillus casei ATCC 334 Site: position = -40 score = 5.24652 sequence = GCAAACGTATGTTCGT Gene: LSEI_1049: UV-damage repair protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	* Lactobacillus fermentum IFO 3956 Site: position = -67 score = 3.94425 sequence = CCGAACACTTGTTCCG Gene: LAF_1605: UV-damage repair protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -192 score = 4.90674 sequence = AAGAACATATGTTCTT Gene: lp_3023: UV-damage repair protein	* Lactobacillus reuteri JCM 1112 Site: position = -59 score = 4.8004 sequence = TTGAACATATGTTTGA Gene: LAR_1238: UV-damage repair protein	* Lactobacillus rhamnosus GG Site: position = -40 score = 5.24652 sequence = GCAAACATACGTTCGT Gene: LGG_01010: UV-damage repair protein	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	* Pediococcus pentosaceus ATCC 25745 Site: position = -41 score = 5.15525 sequence = AAGAACATATGTTCGT Gene: PEPE_1243: UV-damage repair protein	UV-damage repair protein
LVIS_2094	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334 Gene: LSEI_1048: Conserved hypothetical protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG Gene: LGG_01009: Conserved hypothetical protein	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1242: Conserved hypothetical protein	Conserved hypothetical protein
lp_3022	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956 Gene: LAF_1606: Conserved hypothetical protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_3022: Conserved hypothetical protein	Lactobacillus reuteri JCM 1112 Gene: LAR_1237: Conserved hypothetical protein	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Conserved hypothetical protein

CRON 12.
LJ1544	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	* Lactobacillus casei ATCC 334 Site: position = -53 score = 4.34053 sequence = TTGAACACTTGTTCGT Site: position = -26 score = 4.99572 sequence = ACAAACAAATGTTCGG Gene: LSEI_1631: hypothetical protein	* Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Site: position = -71 score = 4.35578 sequence = TCGAATACTCGTTCGT Site: position = -44 score = 4.35122 sequence = ACAAACAGGCGTTCGA Gene: LBUL_1313: hypothetical protein	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	* Lactobacillus johnsonii NCC 533 Site: position = -64 score = 4.85037 sequence = AAAAACATTTGTTCGT Site: position = -36 score = 4.38941 sequence = GCAAACACAAGTTCGG Gene: LJ1544: hypothetical protein	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112	* Lactobacillus rhamnosus GG Site: position = -53 score = 4.52673 sequence = TTGAACACATGTTCGT Site: position = -26 score = 4.91525 sequence = ACAAACAAACGTTCGG Gene: LGG_01676: hypothetical protein	* Lactobacillus sakei subsp. sakei 23K Site: position = -56 score = 4.89442 sequence = TAGAACGTTTGTTCGT Site: position = -29 score = 4.99572 sequence = ACAAACAAATGTTCGG Gene: LSA0683: hypothetical protein	Lactobacillus salivarius subsp. salivarius UCC118	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -54 score = 4.72705 sequence = TTGAACATTTGTTCGT Gene: LEUM_1714: hypothetical protein	* Oenococcus oeni PSU-1 Site: position = -44 score = 4.75641 sequence = TCGAACAAGCGTTCGT Gene: OEOE_1232: hypothetical protein	* Pediococcus pentosaceus ATCC 25745 Site: position = -54 score = 4.68826 sequence = AAGAACGCATGTTCGT Site: position = -27 score = 5.09887 sequence = ACAAACAAATGTTCGT Gene: PEPE_0824: hypothetical protein	hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LexA - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --