Regulog NiaR - Lactobacillaceae

Properties
Regulator type:	Transcription factor
Regulator family:	NiaR
Regulation mode:	repressor
Biological process:	NAD biosynthesis
Effector:	Niacin
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

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Member of regulog collections

By trascription factor - NiaR
By taxonomy - Lactobacillaceae
By TF family - NiaR
By effector - Niacin
By pathway - NAD biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Lactobacillus acidophilus NCFM
Lactobacillus brevis ATCC 367
Lactobacillus casei ATCC 334	1	1
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1	2	2
Lactobacillus reuteri JCM 1112
Lactobacillus rhamnosus GG	1	1
Lactobacillus sakei subsp. sakei 23K	1	1
Lactobacillus salivarius subsp. salivarius UCC118
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Oenococcus oeni PSU-1
Pediococcus pentosaceus ATCC 25745	2	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
niaR	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334 Gene: LSEI_0807: NAD biosynthesis transcription regulator, HTH_11 family	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -121 score = 5.79768 sequence = TTTAGATGTCTTGACACCTATG Gene: lp_2770: NAD biosynthesis transcription regulator, HTH_11 family	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG Gene: LGG_00791: NAD biosynthesis transcription regulator, HTH_11 family	Lactobacillus sakei subsp. sakei 23K Gene: LSA1530: NAD biosynthesis transcription regulator, HTH_11 family	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	* Pediococcus pentosaceus ATCC 25745 Site: position = -64 score = 5.58601 sequence = AATTAATGTCTTGACACTTGTA Gene: PEPE_0214: NAD biosynthesis transcription regulator, HTH_11 family	NAD biosynthesis transcription regulator, HTH_11 family

CRON 2.
niaP	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	* Lactobacillus casei ATCC 334 Site: position = -45 score = 5.00161 sequence = CTAGGGTGTCAAGACACCCTAA Gene: LSEI_2277: Niacin transporter NiaP	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_2514: Niacin transporter NiaP	Lactobacillus reuteri JCM 1112	* Lactobacillus rhamnosus GG Site: position = -51 score = 5.56054 sequence = TTAGGGTGTCAAGACACCTAAT Gene: LGG_02281: Niacin transporter NiaP	* Lactobacillus sakei subsp. sakei 23K Site: position = -76 score = 5.85793 sequence = TTAAGGTGTGTTGACACCTGTA Gene: LSA1529: Niacin transporter NiaP	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0911: Niacin transporter NiaP	Oenococcus oeni PSU-1	* Pediococcus pentosaceus ATCC 25745 Site: position = -112 score = 5.58601 sequence = TACAAGTGTCAAGACATTAATT Gene: PEPE_0213: Niacin transporter NiaP	Niacin transporter NiaP

CRON 3.
pncB	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334 Gene: LSEI_2766: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0276: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Lactobacillus fermentum IFO 3956 Gene: LAF_1391: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Lactobacillus helveticus DPC 4571 Gene: lhv_0930: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -46 score = 5.79768 sequence = CATAGGTGTCAAGACATCTAAA Gene: lp_2771: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Lactobacillus reuteri JCM 1112 Gene: LAR_0148: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Lactobacillus rhamnosus GG Gene: LGG_02765: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1 Gene: OEOE_0890: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Pediococcus pentosaceus ATCC 25745	Nicotinate phosphoribosyltransferase (EC 2.4.2.11)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NiaR - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --