Regulog Cobalamin - Chloroflexia

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Phylum:	Chloroflexi

Member of regulog collections

By taxonomy - Chloroflexi
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Chloroflexus aggregans DSM 9485	26	2
Chloroflexus sp. Y-400-fl	14	3
Roseiflexus castenholzii DSM 13941	23	2
Roseiflexus sp. RS-1	32	3
Herpetosiphon aurantiacus ATCC 23779	16	3

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes						Function

CRON 1.
btuR	* Chloroflexus aggregans DSM 9485 Site: position = -262 score = 62.66 sequence = GCAATTCCATACTCA... Gene: Cagg_1279: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Chloroflexus sp. Y-400-fl Site: position = -272 score = 62.1 sequence = CAAGTTCGTAGATCG... Gene: Chy400_2789: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Roseiflexus castenholzii DSM 13941 Site: position = -424 score = 61.32 sequence = TCAATCCAACGACCG... Gene: Rcas_0649: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Roseiflexus sp. RS-1 Site: position = -361 score = 61.95 sequence = AATGCAACGACCGTC... Gene: RoseRS_0557: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	* Herpetosiphon aurantiacus ATCC 23779 Site: position = -281 score = 59.13 sequence = AATTTACAAGTTTGT... Gene: Haur_1060: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cobN	Chloroflexus aggregans DSM 9485 Gene: Cagg_1278: CobN component of cobalt chelatase involved in B12 biosynthesis	Chloroflexus sp. Y-400-fl Gene: Chy400_2788: CobN component of cobalt chelatase involved in B12 biosynthesis	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0648: CobN component of cobalt chelatase involved in B12 biosynthesis	Roseiflexus sp. RS-1 Gene: RoseRS_0558: CobN component of cobalt chelatase involved in B12 biosynthesis	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1059: CobN component of cobalt chelatase involved in B12 biosynthesis	CobN component of cobalt chelatase involved in B12 biosynthesis
cobT	Chloroflexus aggregans DSM 9485 Gene: Cagg_1277: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Chloroflexus sp. Y-400-fl Gene: Chy400_2787: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0647: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Roseiflexus sp. RS-1 Gene: RoseRS_0559: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Herpetosiphon aurantiacus ATCC 23779	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cbiM	Chloroflexus aggregans DSM 9485 Gene: Cagg_1276: Substrate-specific component CbiM of cobalt ECF transporter	Chloroflexus sp. Y-400-fl Gene: Chy400_2786: Substrate-specific component CbiM of cobalt ECF transporter	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1 Gene: RoseRS_0560: Substrate-specific component CbiM of cobalt ECF transporter	Herpetosiphon aurantiacus ATCC 23779	Substrate-specific component CbiM of cobalt ECF transporter
cbiN	Chloroflexus aggregans DSM 9485 Gene: Cagg_1275: Additional substrate-specific component CbiN of cobalt ECF transporter	Chloroflexus sp. Y-400-fl Gene: Chy400_2785: Additional substrate-specific component CbiN of cobalt ECF transporter	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1 Gene: RoseRS_0561: Additional substrate-specific component CbiN of cobalt ECF transporter	Herpetosiphon aurantiacus ATCC 23779	Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ	Chloroflexus aggregans DSM 9485 Gene: Cagg_1274: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1 Gene: RoseRS_0562: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Herpetosiphon aurantiacus ATCC 23779	Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO	Chloroflexus aggregans DSM 9485 Gene: Cagg_1273: ATPase component CbiO of energizing module of cobalt ECF transporter	Chloroflexus sp. Y-400-fl Gene: Chy400_2783: ATPase component CbiO of energizing module of cobalt ECF transporter	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0646: ATPase component CbiO of energizing module of cobalt ECF transporter	Roseiflexus sp. RS-1 Gene: RoseRS_0563: ATPase component CbiO of energizing module of cobalt ECF transporter	Herpetosiphon aurantiacus ATCC 23779	ATPase component CbiO of energizing module of cobalt ECF transporter
cbiB	Chloroflexus aggregans DSM 9485 Gene: Cagg_1272: Adenosylcobinamide-phosphate synthase	Chloroflexus sp. Y-400-fl Gene: Chy400_2782: Adenosylcobinamide-phosphate synthase	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0645: Adenosylcobinamide-phosphate synthase	Roseiflexus sp. RS-1 Gene: RoseRS_0564: Adenosylcobinamide-phosphate synthase	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1057: Adenosylcobinamide-phosphate synthase	Adenosylcobinamide-phosphate synthase
cbiX	Chloroflexus aggregans DSM 9485 Gene: Cagg_1271: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)	Chloroflexus sp. Y-400-fl Gene: Chy400_2779: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0644: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)	Roseiflexus sp. RS-1 Gene: RoseRS_0565: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)	Herpetosiphon aurantiacus ATCC 23779	Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
wrbA	Chloroflexus aggregans DSM 9485 Gene: Cagg_1270: multimeric flavodoxin WrbA-like protein	Chloroflexus sp. Y-400-fl Gene: Chy400_2778: multimeric flavodoxin WrbA-like protein	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0643: multimeric flavodoxin WrbA-like protein	Roseiflexus sp. RS-1 Gene: RoseRS_0566: multimeric flavodoxin WrbA-like protein	Herpetosiphon aurantiacus ATCC 23779	multimeric flavodoxin WrbA-like protein
cbiC	Chloroflexus aggregans DSM 9485 Gene: Cagg_1269: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Chloroflexus sp. Y-400-fl Gene: Chy400_2777: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0642: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Roseiflexus sp. RS-1 Gene: RoseRS_0567: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Herpetosiphon aurantiacus ATCC 23779	Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiD	Chloroflexus aggregans DSM 9485 Gene: Cagg_1268: Cobalt-precorrin-6 synthase, anaerobic	Chloroflexus sp. Y-400-fl Gene: Chy400_2776: Cobalt-precorrin-6 synthase, anaerobic	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0641: Cobalt-precorrin-6 synthase, anaerobic	Roseiflexus sp. RS-1 Gene: RoseRS_0568: Cobalt-precorrin-6 synthase, anaerobic	Herpetosiphon aurantiacus ATCC 23779	Cobalt-precorrin-6 synthase, anaerobic
cbiET	Chloroflexus aggregans DSM 9485 Gene: Cagg_1267: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Chloroflexus sp. Y-400-fl Gene: Chy400_2775: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0640: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Roseiflexus sp. RS-1 Gene: RoseRS_0569: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Herpetosiphon aurantiacus ATCC 23779	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiL	Chloroflexus aggregans DSM 9485 Gene: Cagg_1266: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Chloroflexus sp. Y-400-fl Gene: Chy400_2774: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0639: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Roseiflexus sp. RS-1 Gene: RoseRS_0570: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Herpetosiphon aurantiacus ATCC 23779	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF	Chloroflexus aggregans DSM 9485 Gene: Cagg_1265: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Chloroflexus sp. Y-400-fl Gene: Chy400_2773: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0638: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Roseiflexus sp. RS-1 Gene: RoseRS_0571: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Herpetosiphon aurantiacus ATCC 23779	Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiGH	Chloroflexus aggregans DSM 9485 Gene: Cagg_1264: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Chloroflexus sp. Y-400-fl Gene: Chy400_2772: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0637: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Roseiflexus sp. RS-1 Gene: RoseRS_0572: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase	Herpetosiphon aurantiacus ATCC 23779	Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
cobA	Chloroflexus aggregans DSM 9485 Gene: Cagg_1263: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Chloroflexus sp. Y-400-fl Gene: Chy400_2771: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0636: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Roseiflexus sp. RS-1 Gene: RoseRS_0573: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Herpetosiphon aurantiacus ATCC 23779	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
cbiA	Chloroflexus aggregans DSM 9485 Gene: Cagg_1262: Cobyrinic acid A,C-diamide synthase	Chloroflexus sp. Y-400-fl Gene: Chy400_2770: Cobyrinic acid A,C-diamide synthase	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0635: Cobyrinic acid A,C-diamide synthase	Roseiflexus sp. RS-1 Gene: RoseRS_0574: Cobyrinic acid A,C-diamide synthase	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2329: Cobyrinic acid A,C-diamide synthase	Cobyrinic acid A,C-diamide synthase
cobU	Chloroflexus aggregans DSM 9485 Gene: Cagg_1261: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Chloroflexus sp. Y-400-fl Gene: Chy400_2769: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0634: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Roseiflexus sp. RS-1 Gene: RoseRS_0575: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1053: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobD	Chloroflexus aggregans DSM 9485 Gene: Cagg_1260: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Chloroflexus sp. Y-400-fl Gene: Chy400_2768: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0633: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Roseiflexus sp. RS-1 Gene: RoseRS_0576: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1052: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiP	Chloroflexus aggregans DSM 9485 Gene: Cagg_1259: Cobyric acid synthase	Chloroflexus sp. Y-400-fl Gene: Chy400_2767: Cobyric acid synthase	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0632: Cobyric acid synthase	Roseiflexus sp. RS-1 Gene: RoseRS_0577: Cobyric acid synthase	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1051: Cobyric acid synthase	Cobyric acid synthase
Haur_1058	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1058: Methyltransferase type 11	Methyltransferase type 11
btuF	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1056: Vitamin B12 ABC transporter, B12-binding component BtuF	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1055: Vitamin B12 ABC transporter, permease component BtuC	Vitamin B12 ABC transporter, permease component BtuC
btuD	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_1054: Vitamin B12 ABC transporter, ATPase component BtuD	Vitamin B12 ABC transporter, ATPase component BtuD

CRON 2.
cbrX	* Chloroflexus aggregans DSM 9485 Site: position = -313 score = 47.26 sequence = TGTATCACCCCACCG... Gene: Cagg_2179: LPXTG-motif cell wall anchor domain protein	* Chloroflexus sp. Y-400-fl Site: position = -267 score = 37.58 sequence = ATCAGACCTGTCCTG... Gene: Chy400_1314: LPXTG-motif cell wall anchor domain protein	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	* Herpetosiphon aurantiacus ATCC 23779 Site: position = -213 score = 47.67 sequence = ATCATAAATTGCTAT... Gene: Haur_3809: LPXTG-motif cell wall anchor domain protein	LPXTG-motif cell wall anchor domain protein
cbrY	Chloroflexus aggregans DSM 9485 Gene: Cagg_2178: hypothetical secreted protein, a putative component of B12 transporter, anchored in the membrane	Chloroflexus sp. Y-400-fl Gene: Chy400_1313: hypothetical secreted protein, a putative component of B12 transporter, anchored in the membrane	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_3810: hypothetical secreted protein, a putative component of B12 transporter, anchored in the membrane	hypothetical secreted protein, a putative component of B12 transporter, anchored in the membrane
cobC	Chloroflexus aggregans DSM 9485 Gene: Cagg_2177: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Chloroflexus sp. Y-400-fl Gene: Chy400_1312: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779	Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cobS	Chloroflexus aggregans DSM 9485 Gene: Cagg_2176: Cobalamin 5'-phosphate synthase	Chloroflexus sp. Y-400-fl Gene: Chy400_1311: Cobalamin 5'-phosphate synthase	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0173: Cobalamin 5'-phosphate synthase	Roseiflexus sp. RS-1 Gene: RoseRS_4584: Cobalamin 5'-phosphate synthase	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_4390: Cobalamin 5'-phosphate synthase	Cobalamin 5'-phosphate synthase
cbrV	Chloroflexus aggregans DSM 9485 Gene: Cagg_2175: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Chloroflexus sp. Y-400-fl Gene: Chy400_1310: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_3811: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter

CRON 3.
nrdA	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	* Herpetosiphon aurantiacus ATCC 23779 Site: position = -279 score = 33.58 sequence = TACAAATTTTTTTGA... Gene: Haur_2575: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
nrdB	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2574: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
metE	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2573: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

CRON 4.
RoseRS_3103	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	* Roseiflexus sp. RS-1 Site: position = -344 score = 63.78 sequence = TAAACCTTTCAAACG... Gene: RoseRS_3103: hypothetical protein	Herpetosiphon aurantiacus ATCC 23779	hypothetical protein
RoseRS_3102	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1 Gene: RoseRS_3102: Core component MTH452 of predicted ECF transporter	Herpetosiphon aurantiacus ATCC 23779	Core component MTH452 of predicted ECF transporter
RoseRS_3101	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1 Gene: RoseRS_3101: Transmembrane component of energizing module of ECF transporters	Herpetosiphon aurantiacus ATCC 23779	Transmembrane component of energizing module of ECF transporters
RoseRS_3100	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1 Gene: RoseRS_3100: Duplicated ATPase component of energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters	Herpetosiphon aurantiacus ATCC 23779	Duplicated ATPase component of energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters
cobN	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1 Gene: RoseRS_3099: Cobaltochelatase subunit CobN	Herpetosiphon aurantiacus ATCC 23779	Cobaltochelatase subunit CobN
RoseRS_3098	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1 Gene: RoseRS_3098: hypothetical protein	Herpetosiphon aurantiacus ATCC 23779	hypothetical protein

CRON 5.
Rcas_2247	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	* Roseiflexus castenholzii DSM 13941 Site: position = -325 score = 64.2 sequence = CAAGTGAATACCATC... Gene: Rcas_2247: hypothetical protein	* Roseiflexus sp. RS-1 Site: position = -197 score = 65.42 sequence = CAAGTGAATACCATC... Gene: RoseRS_3085: hypothetical protein	Herpetosiphon aurantiacus ATCC 23779	hypothetical protein
btuF	Chloroflexus aggregans DSM 9485	* Chloroflexus sp. Y-400-fl Site: position = -421 score = 66.09 sequence = CAAGTTCATATCGTC... Gene: Chy400_0336: Vitamin B12 ABC transporter, B12-binding component BtuF	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2248: Vitamin B12 ABC transporter, B12-binding component BtuF	Roseiflexus sp. RS-1 Gene: RoseRS_3086: Vitamin B12 ABC transporter, B12-binding component BtuF	Herpetosiphon aurantiacus ATCC 23779	Vitamin B12 ABC transporter, B12-binding component BtuF
cbiW	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl Gene: Chy400_0337: ferredoxin-like protein	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2249: ferredoxin-like protein	Roseiflexus sp. RS-1 Gene: RoseRS_3087: ferredoxin-like protein	Herpetosiphon aurantiacus ATCC 23779	ferredoxin-like protein
btuC	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl Gene: Chy400_0338: Vitamin B12 ABC transporter, permease component BtuC	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2250: Vitamin B12 ABC transporter, permease component BtuC	Roseiflexus sp. RS-1 Gene: RoseRS_3088: Vitamin B12 ABC transporter, permease component BtuC	Herpetosiphon aurantiacus ATCC 23779	Vitamin B12 ABC transporter, permease component BtuC
btuD	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl Gene: Chy400_0339: Vitamin B12 ABC transporter, ATP-binding component BtuD	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2251: Vitamin B12 ABC transporter, ATP-binding component BtuD	Roseiflexus sp. RS-1 Gene: RoseRS_3089: Vitamin B12 ABC transporter, ATP-binding component BtuD	Herpetosiphon aurantiacus ATCC 23779	Vitamin B12 ABC transporter, ATP-binding component BtuD

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Cobalamin - Chloroflexia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --