Regulon of Cobalamin in Roseiflexus sp. RS-1

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Regulog:	Cobalamin - Chloroflexia
Under regulation:
- Genes	32
- Operons	3

Member of regulog collections

By taxonomy - Chloroflexi
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -344 Score: 63.8 Sequence: TAAACCTTTCAAACG... Locus tag: RoseRS_3103 Name: null Funciton: hypothetical protein Locus tag: RoseRS_3102 Name: RoseRS_3102 Funciton: Core component MTH452 of predicted ECF transporter Locus tag: RoseRS_3101 Name: RoseRS_3101 Funciton: Transmembrane component of energizing module of ECF transporters Locus tag: RoseRS_3100 Name: RoseRS_3100 Funciton: Duplicated ATPase component of energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters Locus tag: RoseRS_3099 Name: cobN Funciton: Cobaltochelatase subunit CobN Locus tag: RoseRS_3098 Name: null Funciton: hypothetical protein
	RoseRS_3103		hypothetical protein
	RoseRS_3102	RoseRS_3102	Core component MTH452 of predicted ECF transporter
	RoseRS_3101	RoseRS_3101	Transmembrane component of energizing module of ECF transporters
	RoseRS_3100	RoseRS_3100	Duplicated ATPase component of energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters
	RoseRS_3099	cobN	Cobaltochelatase subunit CobN
	RoseRS_3098		hypothetical protein
Position: -361 Score: 62 Sequence: AATGCAACGACCGTC... Locus tag: RoseRS_0557 Name: btuR Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) Locus tag: RoseRS_0558 Name: cobN Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis Locus tag: RoseRS_0559 Name: cobT Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) Locus tag: RoseRS_0560 Name: cbiM Funciton: Substrate-specific component CbiM of cobalt ECF transporter Locus tag: RoseRS_0561 Name: cbiN Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter Locus tag: RoseRS_0562 Name: cbiQ Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter Locus tag: RoseRS_0563 Name: cbiO Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter Locus tag: RoseRS_0564 Name: cbiB Funciton: Adenosylcobinamide-phosphate synthase Locus tag: RoseRS_0565 Name: cbiX Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) Locus tag: RoseRS_0566 Name: wrbA Funciton: multimeric flavodoxin WrbA-like protein Locus tag: RoseRS_0567 Name: cbiC Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) Locus tag: RoseRS_0568 Name: cbiD Funciton: Cobalt-precorrin-6 synthase, anaerobic Locus tag: RoseRS_0569 Name: cbiET Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) Locus tag: RoseRS_0570 Name: cbiL Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) Locus tag: RoseRS_0571 Name: cbiF Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) Locus tag: RoseRS_0572 Name: cbiGH Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase Locus tag: RoseRS_0573 Name: cobA Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) Locus tag: RoseRS_0574 Name: cbiA Funciton: Cobyrinic acid A,C-diamide synthase Locus tag: RoseRS_0575 Name: cobU Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) Locus tag: RoseRS_0576 Name: cobD Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) Locus tag: RoseRS_0577 Name: cbiP Funciton: Cobyric acid synthase
	RoseRS_0557	btuR	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
	RoseRS_0558	cobN	CobN component of cobalt chelatase involved in B12 biosynthesis
	RoseRS_0559	cobT	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
	RoseRS_0560	cbiM	Substrate-specific component CbiM of cobalt ECF transporter
	RoseRS_0561	cbiN	Additional substrate-specific component CbiN of cobalt ECF transporter
	RoseRS_0562	cbiQ	Transmembrane component CbiQ of energizing module of cobalt ECF transporter
	RoseRS_0563	cbiO	ATPase component CbiO of energizing module of cobalt ECF transporter
	RoseRS_0564	cbiB	Adenosylcobinamide-phosphate synthase
	RoseRS_0565	cbiX	Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
	RoseRS_0566	wrbA	multimeric flavodoxin WrbA-like protein
	RoseRS_0567	cbiC	Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
	RoseRS_0568	cbiD	Cobalt-precorrin-6 synthase, anaerobic
	RoseRS_0569	cbiET	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
	RoseRS_0570	cbiL	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
	RoseRS_0571	cbiF	Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
	RoseRS_0572	cbiGH	Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
	RoseRS_0573	cobA	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
	RoseRS_0574	cbiA	Cobyrinic acid A,C-diamide synthase
	RoseRS_0575	cobU	Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
	RoseRS_0576	cobD	L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
	RoseRS_0577	cbiP	Cobyric acid synthase
Position: -197 Score: 65.4 Sequence: CAAGTGAATACCATC... Locus tag: RoseRS_3085 Name: null Funciton: hypothetical protein Locus tag: RoseRS_3086 Name: btuF Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF Locus tag: RoseRS_3087 Name: cbiW Funciton: ferredoxin-like protein Locus tag: RoseRS_3088 Name: btuC Funciton: Vitamin B12 ABC transporter, permease component BtuC Locus tag: RoseRS_3089 Name: btuD Funciton: Vitamin B12 ABC transporter, ATP-binding component BtuD
	RoseRS_3085		hypothetical protein
	RoseRS_3086	btuF	Vitamin B12 ABC transporter, B12-binding component BtuF
	RoseRS_3087	cbiW	ferredoxin-like protein
	RoseRS_3088	btuC	Vitamin B12 ABC transporter, permease component BtuC
	RoseRS_3089	btuD	Vitamin B12 ABC transporter, ATP-binding component BtuD

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Cobalamin in Roseiflexus sp. RS-1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --