Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing cobU gene

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Phylum: Chloroflexi
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Chloroflexus aggregans DSM 9485
Position: -262
Score: 62.66
Sequence: GCAATTCCATACTCA...
Locus tag: Cagg_1279
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: Cagg_1278
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Cagg_1277
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Cagg_1276
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: Cagg_1275
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: Cagg_1274
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: Cagg_1273
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: Cagg_1272
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Cagg_1271
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: Cagg_1270
Name: wrbA
Funciton: multimeric flavodoxin WrbA-like protein
Locus tag: Cagg_1269
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Cagg_1268
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: Cagg_1267
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Cagg_1266
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Cagg_1265
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Cagg_1264
Name: cbiGH
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Cagg_1263
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: Cagg_1262
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: Cagg_1261
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Cagg_1260
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Cagg_1259
Name: cbiP
Funciton: Cobyric acid synthase
btuR-cobN-cobT-cbiM-cbiN-cbiQ-cbiO-cbiB-cbiX-wrbA-cbiC-cbiD-cbiET-cbiL-cbiF-cbiGH-cobA-cbiA-cobU-cobD-cbiP -262 62.7 GCAATTCCATACTCA... Cagg_1279
Herpetosiphon aurantiacus ATCC 23779
Position: -281
Score: 59.13
Sequence: AATTTACAAGTTTGT...
Locus tag: Haur_1060
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: Haur_1059
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Haur_1058
Name: null
Funciton: Methyltransferase type 11
Locus tag: Haur_1057
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Haur_1056
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: Haur_1055
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Haur_1054
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: Haur_1053
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Haur_1052
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Haur_1051
Name: cbiP
Funciton: Cobyric acid synthase
btuR-cobN-Haur_1058-cbiB-btuF-btuC-btuD-cobU-cobD-cbiP -281 59.1 AATTTACAAGTTTGT... Haur_1060
Roseiflexus castenholzii DSM 13941
Position: -424
Score: 61.32
Sequence: TCAATCCAACGACCG...
Locus tag: Rcas_0649
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: Rcas_0648
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Rcas_0647
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Rcas_0646
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: Rcas_0645
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Rcas_0644
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: Rcas_0643
Name: wrbA
Funciton: multimeric flavodoxin WrbA-like protein
Locus tag: Rcas_0642
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Rcas_0641
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: Rcas_0640
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Rcas_0639
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Rcas_0638
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Rcas_0637
Name: cbiGH
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Rcas_0636
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: Rcas_0635
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: Rcas_0634
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Rcas_0633
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Rcas_0632
Name: cbiP
Funciton: Cobyric acid synthase
btuR-cobN-cobT-cbiO-cbiB-cbiX-wrbA-cbiC-cbiD-cbiET-cbiL-cbiF-cbiGH-cobA-cbiA-cobU-cobD-cbiP -424 61.3 TCAATCCAACGACCG... Rcas_0649
Roseiflexus sp. RS-1
Position: -361
Score: 61.95
Sequence: AATGCAACGACCGTC...
Locus tag: RoseRS_0557
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: RoseRS_0558
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: RoseRS_0559
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: RoseRS_0560
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: RoseRS_0561
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: RoseRS_0562
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: RoseRS_0563
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: RoseRS_0564
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: RoseRS_0565
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: RoseRS_0566
Name: wrbA
Funciton: multimeric flavodoxin WrbA-like protein
Locus tag: RoseRS_0567
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: RoseRS_0568
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: RoseRS_0569
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: RoseRS_0570
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: RoseRS_0571
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: RoseRS_0572
Name: cbiGH
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
Locus tag: RoseRS_0573
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: RoseRS_0574
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: RoseRS_0575
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: RoseRS_0576
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: RoseRS_0577
Name: cbiP
Funciton: Cobyric acid synthase
btuR-cobN-cobT-cbiM-cbiN-cbiQ-cbiO-cbiB-cbiX-wrbA-cbiC-cbiD-cbiET-cbiL-cbiF-cbiGH-cobA-cbiA-cobU-cobD-cbiP -361 62 AATGCAACGACCGTC... RoseRS_0557