Regulog NrdR - Pseudomonadaceae

Properties
Regulator type:	Transcription factor
Regulator family:	NrdR
Regulation mode:	repressor
Biological process:	Deoxyribonucleotide biosynthesis
Effector:	Deoxyribonucleotides
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 35 sites [see more]

Member of regulog collections

By taxonomy - Pseudomonadaceae
By trascription factor - NrdR
By TF family - NrdR
By effector - Deoxyribonucleotides
By pathway - Deoxyribonucleotide biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Pseudomonas aeruginosa PAO1	7	4
Pseudomonas entomophila L48	3	3
Pseudomonas putida KT2440	3	3
Pseudomonas syringae pv. tomato str. DC3000	3	3
Pseudomonas fluorescens Pf-5	3	3
Pseudomonas mendocina ymp	2	2
Pseudomonas stutzeri A1501	6	3
Azotobacter vinelandii AvOP	3	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
nrdA	* Pseudomonas aeruginosa PAO1 Site: position = -398 score = 4.8741 sequence = CCCCTATATCTTGGGT Site: position = -194 score = 5.0483 sequence = CCACTAGGTATTGTGT Gene: PA1156: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Pseudomonas entomophila L48 Site: position = -432 score = 3.38984 sequence = CCGCATTATCTTGTAT Site: position = -401 score = 5.44143 sequence = CCACTAGATGTTGGGT Gene: PSEEN1337: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Pseudomonas putida KT2440 Site: position = -428 score = 3.38984 sequence = CCGCATTATCTTGTAT Site: position = -397 score = 5.61153 sequence = CCACTAGATATAGGGG Gene: PP1179: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = -352 score = 4.96218 sequence = ACCCTACATGTAGGGT Gene: PSPTO1671: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Pseudomonas fluorescens Pf-5 Site: position = -375 score = 4.57877 sequence = TCCCTATATCTAGGGT Gene: PFL_4476: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Pseudomonas mendocina ymp Site: position = -407 score = 5.12509 sequence = CCACCAGATATTGGGT Site: position = -214 score = 5.08567 sequence = CCACTATATGTAGTAG Gene: Pmen_3151: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Pseudomonas stutzeri A1501 Site: position = -202 score = 5.21223 sequence = ACACAACATATTGTGT Site: position = -392 score = 5.12427 sequence = CCCCTAGATGTTGGGT Gene: PST_1637: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Azotobacter vinelandii AvOP Site: position = -163 score = 5.42064 sequence = CCACTAGATGTTGTGG Site: position = -352 score = 5.02149 sequence = CCCCTACATATAGGGA Gene: Avin_33290: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
nrdB	Pseudomonas aeruginosa PAO1 Gene: PA1155: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	* Pseudomonas entomophila L48 Site: position = -453 score = 4.27906 sequence = ACACCATATGCTGTGG Site: position = -422 score = 4.8414 sequence = ACACAACATATAGGAT Gene: PSEEN1335: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	* Pseudomonas putida KT2440 Site: position = -343 score = 4.68858 sequence = GCACAACATATAGGTT Site: position = -375 score = 3.82803 sequence = ACACCATATGATGTGC Gene: PP1177: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = -447 score = 4.38541 sequence = TCACTATATGCTGCGC Site: position = -415 score = 3.93729 sequence = ACACTACATAAGGGAT Gene: PSPTO1661: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	* Pseudomonas fluorescens Pf-5 Site: position = -434 score = 4.06353 sequence = ACACAACATCTAGTAA Gene: PFL_4524: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Pseudomonas mendocina ymp Gene: Pmen_3152: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Pseudomonas stutzeri A1501 Gene: PST_1636: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Azotobacter vinelandii AvOP Gene: Avin_33300: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)

CRON 2.
topA	* Pseudomonas aeruginosa PAO1 Site: position = -76 score = 5.68694 sequence = CCACTATATATAGCGG Gene: PA3011: DNA topoisomerase I (EC 5.99.1.2)	* Pseudomonas entomophila L48 Site: position = -73 score = 5.68694 sequence = CCACTATATATAGCGG Gene: PSEEN3725: DNA topoisomerase I (EC 5.99.1.2)	* Pseudomonas putida KT2440 Site: position = -73 score = 5.68694 sequence = CCACTATATATAGCGG Gene: PP2139: DNA topoisomerase I (EC 5.99.1.2)	* Pseudomonas syringae pv. tomato str. DC3000 Site: position = -71 score = 5.68694 sequence = CCACTATATATAGCGT Gene: PSPTO3514: DNA topoisomerase I (EC 5.99.1.2)	* Pseudomonas fluorescens Pf-5 Site: position = -72 score = 5.68694 sequence = CCACTATATATAGCGG Gene: PFL_1942: DNA topoisomerase I (EC 5.99.1.2)	* Pseudomonas mendocina ymp Site: position = -69 score = 5.68694 sequence = CCACTATATATAGCGG Gene: Pmen_1583: DNA topoisomerase I (EC 5.99.1.2)	* Pseudomonas stutzeri A1501 Site: position = -241 score = 5.68694 sequence = CCACTATATATAGCGG Gene: PST_1729: DNA topoisomerase I (EC 5.99.1.2)	* Azotobacter vinelandii AvOP Site: position = -222 score = 5.39327 sequence = CCACTATATATAGCGC Gene: Avin_14470: DNA topoisomerase I (EC 5.99.1.2)	DNA topoisomerase I (EC 5.99.1.2)

CRON 3.
nrdD	* Pseudomonas aeruginosa PAO1 Site: position = -57 score = 5.10769 sequence = CCACAACATATTGTTG Site: position = -26 score = 4.53379 sequence = ACACATCATGTTGTGG Gene: PA1920: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	* Pseudomonas stutzeri A1501 Site: position = -58 score = 4.57793 sequence = TCACACCATATTGTGG Site: position = -27 score = 4.41333 sequence = ACACTACATATGGTTA Gene: PST_3509: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Azotobacter vinelandii AvOP	Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
PST_3508	Pseudomonas aeruginosa PAO1	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501 Gene: PST_3508: hypothetical protein	Azotobacter vinelandii AvOP	hypothetical protein
nrdG	Pseudomonas aeruginosa PAO1 Gene: PA1919: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501 Gene: PST_3507: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Azotobacter vinelandii AvOP	Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

CRON 4.
nrdJb	* Pseudomonas aeruginosa PAO1 Site: position = -38 score = 4.5837 sequence = ACACAAGATATTGATT Site: position = -7 score = 4.62243 sequence = TAACTAGATGTTGCGT Gene: PA5497: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501 Gene: PST_0109: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)	Azotobacter vinelandii AvOP Gene: Avin_00810: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)	Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)
nrdJa	Pseudomonas aeruginosa PAO1 Gene: PA5496: Ribonucleotide reductase of class II (coenzyme B12-dependent), alpha subunit (EC 1.17.4.1)	Pseudomonas entomophila L48	Pseudomonas putida KT2440	Pseudomonas syringae pv. tomato str. DC3000	Pseudomonas fluorescens Pf-5	Pseudomonas mendocina ymp	Pseudomonas stutzeri A1501 Gene: PST_0110: Ribonucleotide reductase of class II (coenzyme B12-dependent), alpha subunit (EC 1.17.4.1)	Azotobacter vinelandii AvOP Gene: Avin_00800: Ribonucleotide reductase of class II (coenzyme B12-dependent), alpha subunit (EC 1.17.4.1)	Ribonucleotide reductase of class II (coenzyme B12-dependent), alpha subunit (EC 1.17.4.1)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NrdR - Pseudomonadaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --