Statistics of regulated genes

Genome	Genes	Operons
Macrococcus caseolyticus JCSC5402	12	6
Staphylococcus aureus subsp. aureus N315	7	2
Staphylococcus capitis SK14	12	4
Staphylococcus carnosus subsp. carnosus TM300	15	5
Staphylococcus epidermidis ATCC 12228	14	5
Staphylococcus haemolyticus JCSC1435	13	4
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	13	4

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes								Function
CRON 1.
thiE	* Macrococcus caseolyticus JCSC5402 Site: position = -173 score = 76.77 sequence = GAATATGTGCTAGGG... Gene: MCCL_0120: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Staphylococcus aureus subsp. aureus N315	* Staphylococcus capitis SK14 Site: position = -189 score = 84.48 sequence = ATCAATCCACTGGAA... Gene: STACA0001_1001: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -280 score = 78.7 sequence = AAGTCCACTGGAAGT... Gene: Sca_2076: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	* Staphylococcus epidermidis ATCC 12228 Site: position = -295 score = 86.94 sequence = TTAACCACTGGAAGT... Gene: SE2057: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	* Staphylococcus haemolyticus JCSC1435 Site: position = -171 score = 82.14 sequence = ATTTATCCACTGGAA... Gene: SH0565: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -107 score = 72.39 sequence = TAGAAACCACTGGAA... Gene: SSPP136: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiO	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0119: Glycine oxidase ThiO (EC 1.4.3.19)	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14 Gene: STACA0001_1000: Glycine oxidase ThiO (EC 1.4.3.19)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2077: Glycine oxidase ThiO (EC 1.4.3.19)	Staphylococcus epidermidis ATCC 12228 Gene: SE2058: Glycine oxidase ThiO (EC 1.4.3.19)	Staphylococcus haemolyticus JCSC1435 Gene: SH0564: Glycine oxidase ThiO (EC 1.4.3.19)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSPP135: Glycine oxidase ThiO (EC 1.4.3.19)	Glycine oxidase ThiO (EC 1.4.3.19)
thiS	Macrococcus caseolyticus JCSC5402	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2078: Sulfur carrier protein ThiS	Staphylococcus epidermidis ATCC 12228 Gene: SE2059: Sulfur carrier protein ThiS	Staphylococcus haemolyticus JCSC1435 Gene: SH0563: Sulfur carrier protein ThiS	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSPP134: Sulfur carrier protein ThiS	Sulfur carrier protein ThiS
thiG	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0118: Thiazole synthase	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14 Gene: STACA0001_0998: Thiazole synthase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2079: Thiazole synthase	Staphylococcus epidermidis ATCC 12228 Gene: SE2060: Thiazole synthase	Staphylococcus haemolyticus JCSC1435 Gene: SH0562: Thiazole synthase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSPP133: Thiazole synthase	Thiazole synthase
thiF	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0117: Sulfur carrier protein adenylyltransferase ThiF	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14 Gene: STACA0001_0997: Sulfur carrier protein adenylyltransferase ThiF	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2080: Sulfur carrier protein adenylyltransferase ThiF	Staphylococcus epidermidis ATCC 12228 Gene: SE2061: Sulfur carrier protein adenylyltransferase ThiF	Staphylococcus haemolyticus JCSC1435 Gene: SH0561: Sulfur carrier protein adenylyltransferase ThiF	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSPP132: Sulfur carrier protein adenylyltransferase ThiF	Sulfur carrier protein adenylyltransferase ThiF
CRON 2.
ykoE	Macrococcus caseolyticus JCSC5402	* Staphylococcus aureus subsp. aureus N315 Site: position = -178 score = 72.36 sequence = TCGCACACACTAGGG... Gene: SA0929: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Staphylococcus capitis SK14 Site: position = -188 score = 74.19 sequence = GGACGCACTAGGGGT... Gene: STACA0001_2287: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -209 score = 77.25 sequence = TAGAAAGCACTAGGG... Gene: Sca_0700: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Staphylococcus epidermidis ATCC 12228 Site: position = -188 score = 69.71 sequence = TTGAACGCACTAGGG... Gene: SE0775: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Staphylococcus haemolyticus JCSC1435 Site: position = -185 score = 77.09 sequence = AAATGCACTAGGGGT... Gene: SH1880: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -187 score = 76.44 sequence = ATTCGCACTAGGGGT... Gene: SSP1713: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
ykoD	Macrococcus caseolyticus JCSC5402	Staphylococcus aureus subsp. aureus N315 Gene: SA0928: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus capitis SK14 Gene: STACA0001_2288: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0699: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus epidermidis ATCC 12228 Gene: SE0774: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus haemolyticus JCSC1435 Gene: SH1881: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1714: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
ykoC	Macrococcus caseolyticus JCSC5402	Staphylococcus aureus subsp. aureus N315 Gene: SA0927: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus capitis SK14 Gene: STACA0001_2289: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0698: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus epidermidis ATCC 12228 Gene: SE0773: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus haemolyticus JCSC1435 Gene: SH1882: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1715: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
CRON 3.
oarX	Macrococcus caseolyticus JCSC5402	Staphylococcus aureus subsp. aureus N315	* Staphylococcus capitis SK14 Site: position = -193 score = 69.86 sequence = ATTTACACTAGGGGT... Gene: STACA0001_0474: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -206 score = 81.31 sequence = ATACGCACTAGGGGT... Gene: Sca_2279: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX	* Staphylococcus epidermidis ATCC 12228 Site: position = -195 score = 81.03 sequence = TTATATGCACTAGGG... Gene: SE0324: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX	Staphylococcus haemolyticus JCSC1435	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -204 score = 79.86 sequence = AAATGCACTAGGGGT... Gene: SSP1530: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX	Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX
CRON 4.
thiC	* Macrococcus caseolyticus JCSC5402 Site: position = -162 score = 74.34 sequence = ACGATTGCTAGGGGA... Gene: MCCL_0298: Phosphomethylpyrimidine synthase ThiC	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	*2 Staphylococcus carnosus subsp. carnosus TM300 Site: position = -280 score = 71.51 sequence = TTCATTGCTAGGGGT... Gene: Sca_0594: Phosphomethylpyrimidine synthase ThiC Gene: Sca_0595: Phosphomethylpyrimidine synthase ThiC	Staphylococcus epidermidis ATCC 12228	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Phosphomethylpyrimidine synthase ThiC
CRON 5.
thiT	* Macrococcus caseolyticus JCSC5402 Site: position = -57 score = 49.35 sequence = TATGAACCACAAGCG... Gene: MCCL_1450: Substrate-specific component ThiT of thiamin ECF transporter	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus epidermidis ATCC 12228	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Substrate-specific component ThiT of thiamin ECF transporter
CRON 6.
tenA	*2 Macrococcus caseolyticus JCSC5402 Site: position = -158 score = 62.66 sequence = ATATATACACTAGGG... Gene: MCCL_1749: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA Site: position = -86 score = 71.83 sequence = AATATCACTAGGGGT... Gene: MCCL_0787: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA	* Staphylococcus aureus subsp. aureus N315 Site: position = -183 score = 76.91 sequence = AAGGAACTACTAGGG... Gene: SA1897: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA	* Staphylococcus capitis SK14 Site: position = -177 score = 76.92 sequence = TATTAACTACTAGGG... Gene: STACA0001_0798: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -165 score = 73.28 sequence = ATAAAATTGCTAGGG... Gene: Sca_1596: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA	* Staphylococcus epidermidis ATCC 12228 Site: position = -171 score = 85.11 sequence = TATTTGCTACTAGGG... Gene: SE1693: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA	* Staphylococcus haemolyticus JCSC1435 Site: position = -177 score = 84.11 sequence = AATGCTACTAGGGGA... Gene: SH0940: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -175 score = 83.55 sequence = AACGCTACTAGGGGA... Gene: SSP0789: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA	4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA
thiD	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1748: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Staphylococcus aureus subsp. aureus N315 Gene: SA1896: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Staphylococcus capitis SK14 Gene: STACA0001_0797: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1595: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Staphylococcus epidermidis ATCC 12228 Gene: SE1692: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Staphylococcus haemolyticus JCSC1435 Gene: SH0941: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0790: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Phosphomethylpyrimidine kinase (EC 2.7.4.7)
thiM	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1747: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Staphylococcus aureus subsp. aureus N315 Gene: SA1895: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Staphylococcus capitis SK14 Gene: STACA0001_0796: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1594: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Staphylococcus epidermidis ATCC 12228 Gene: SE1691: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Staphylococcus haemolyticus JCSC1435 Gene: SH0942: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0791: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1746: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Staphylococcus aureus subsp. aureus N315 Gene: SA1894: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Staphylococcus capitis SK14 Gene: STACA0001_0795: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1593: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Staphylococcus epidermidis ATCC 12228 Gene: SE1690: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Staphylococcus haemolyticus JCSC1435 Gene: SH0943: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0792: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
CRON 7.
thiY	* Macrococcus caseolyticus JCSC5402 Site: position = -132 score = 66.88 sequence = TTAAACACTAGGGGA... Gene: MCCL_0880: Hydroxymethylpyrimidine ABC transporter, substrate-binding component	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus epidermidis ATCC 12228 Site: position = -159 score = 67.31 sequence = CTAGTATCACTAGGG... Gene: SE0251: Hydroxymethylpyrimidine ABC transporter, substrate-binding component	* Staphylococcus haemolyticus JCSC1435 Site: position = -161 score = 70.96 sequence = AAAAAATCACTAGGG... Gene: SH0246: Hydroxymethylpyrimidine ABC transporter, substrate-binding component	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Hydroxymethylpyrimidine ABC transporter, substrate-binding component

Export

	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD