Regulog TPP - Staphylococcaceae
| Regulator type: | RNA regulatory element |
| Name: | TPP |
| RFAM: | RF00059 |
| Regulation mode: | |
| Biological process: | Thiamine biosynthesis |
| Effector: | Thiamine pyrophosphate |
| Phylum: | Firmicutes |
Member of regulog collections
- By taxonomy - Staphylococcaceae
- By RNA motif - TPP
- By effector - Thiamine pyrophosphate
- By pathway - Thiamine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Macrococcus caseolyticus JCSC5402 | 12 | 6 |
| Staphylococcus aureus subsp. aureus N315 | 7 | 2 |
| Staphylococcus capitis SK14 | 12 | 4 |
| Staphylococcus carnosus subsp. carnosus TM300 | 15 | 5 |
| Staphylococcus epidermidis ATCC 12228 | 14 | 5 |
| Staphylococcus haemolyticus JCSC1435 | 13 | 4 |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | 13 | 4 |
| Genes | Function | |||||||
|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||
| thiE |
*
Macrococcus caseolyticus JCSC5402 Site: position = -173 score = 76.77 sequence = GAATATGTGCTAGGG... Gene: MCCL_0120: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
|
*
Staphylococcus capitis SK14 Site: position = -189 score = 84.48 sequence = ATCAATCCACTGGAA... Gene: STACA0001_1001: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
*
Staphylococcus carnosus subsp. carnosus TM300 Site: position = -280 score = 78.7 sequence = AAGTCCACTGGAAGT... Gene: Sca_2076: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
*
Staphylococcus epidermidis ATCC 12228 Site: position = -295 score = 86.94 sequence = TTAACCACTGGAAGT... Gene: SE2057: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
*
Staphylococcus haemolyticus JCSC1435 Site: position = -171 score = 82.14 sequence = ATTTATCCACTGGAA... Gene: SH0565: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -107 score = 72.39 sequence = TAGAAACCACTGGAA... Gene: SSPP136: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
| thiO |
Gene: MCCL_0119: Glycine oxidase ThiO (EC 1.4.3.19) |
|
Gene: STACA0001_1000: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: Sca_2077: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: SE2058: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: SH0564: Glycine oxidase ThiO (EC 1.4.3.19) |
Gene: SSPP135: Glycine oxidase ThiO (EC 1.4.3.19) |
Glycine oxidase ThiO (EC 1.4.3.19) |
| thiS |
|
|
|
Gene: Sca_2078: Sulfur carrier protein ThiS |
Gene: SE2059: Sulfur carrier protein ThiS |
Gene: SH0563: Sulfur carrier protein ThiS |
Gene: SSPP134: Sulfur carrier protein ThiS |
Sulfur carrier protein ThiS |
| thiG |
Gene: MCCL_0118: Thiazole synthase |
|
Gene: STACA0001_0998: Thiazole synthase |
Gene: Sca_2079: Thiazole synthase |
Gene: SE2060: Thiazole synthase |
Gene: SH0562: Thiazole synthase |
Gene: SSPP133: Thiazole synthase |
Thiazole synthase |
| thiF |
Gene: MCCL_0117: Sulfur carrier protein adenylyltransferase ThiF |
|
Gene: STACA0001_0997: Sulfur carrier protein adenylyltransferase ThiF |
Gene: Sca_2080: Sulfur carrier protein adenylyltransferase ThiF |
Gene: SE2061: Sulfur carrier protein adenylyltransferase ThiF |
Gene: SH0561: Sulfur carrier protein adenylyltransferase ThiF |
Gene: SSPP132: Sulfur carrier protein adenylyltransferase ThiF |
Sulfur carrier protein adenylyltransferase ThiF |
| CRON 2. | ||||||||
| ykoE |
|
*
Staphylococcus aureus subsp. aureus N315 Site: position = -178 score = 72.36 sequence = TCGCACACACTAGGG... Gene: SA0929: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Staphylococcus capitis SK14 Site: position = -188 score = 74.19 sequence = GGACGCACTAGGGGT... Gene: STACA0001_2287: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Staphylococcus carnosus subsp. carnosus TM300 Site: position = -209 score = 77.25 sequence = TAGAAAGCACTAGGG... Gene: Sca_0700: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Staphylococcus epidermidis ATCC 12228 Site: position = -188 score = 69.71 sequence = TTGAACGCACTAGGG... Gene: SE0775: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Staphylococcus haemolyticus JCSC1435 Site: position = -185 score = 77.09 sequence = AAATGCACTAGGGGT... Gene: SH1880: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -187 score = 76.44 sequence = ATTCGCACTAGGGGT... Gene: SSP1713: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| ykoD |
|
Gene: SA0928: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: STACA0001_2288: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: Sca_0699: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: SE0774: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: SH1881: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: SSP1714: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| ykoC |
|
Gene: SA0927: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: STACA0001_2289: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: Sca_0698: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: SE0773: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: SH1882: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: SSP1715: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| CRON 3. | ||||||||
| oarX |
|
|
*
Staphylococcus capitis SK14 Site: position = -193 score = 69.86 sequence = ATTTACACTAGGGGT... Gene: STACA0001_0474: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX |
*
Staphylococcus carnosus subsp. carnosus TM300 Site: position = -206 score = 81.31 sequence = ATACGCACTAGGGGT... Gene: Sca_2279: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX |
*
Staphylococcus epidermidis ATCC 12228 Site: position = -195 score = 81.03 sequence = TTATATGCACTAGGG... Gene: SE0324: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX |
|
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -204 score = 79.86 sequence = AAATGCACTAGGGGT... Gene: SSP1530: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX |
Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX |
| CRON 4. | ||||||||
| thiC |
*
Macrococcus caseolyticus JCSC5402 Site: position = -162 score = 74.34 sequence = ACGATTGCTAGGGGA... Gene: MCCL_0298: Phosphomethylpyrimidine synthase ThiC |
|
|
*2
Staphylococcus carnosus subsp. carnosus TM300 Site: position = -280 score = 71.51 sequence = TTCATTGCTAGGGGT... Gene: Sca_0594: Phosphomethylpyrimidine synthase ThiC Gene: Sca_0595: Phosphomethylpyrimidine synthase ThiC |
|
|
|
Phosphomethylpyrimidine synthase ThiC |
| CRON 5. | ||||||||
| thiT |
*
Macrococcus caseolyticus JCSC5402 Site: position = -57 score = 49.35 sequence = TATGAACCACAAGCG... Gene: MCCL_1450: Substrate-specific component ThiT of thiamin ECF transporter |
|
|
|
|
|
|
Substrate-specific component ThiT of thiamin ECF transporter |
| CRON 6. | ||||||||
| tenA |
*2
Macrococcus caseolyticus JCSC5402 Site: position = -158 score = 62.66 sequence = ATATATACACTAGGG... Gene: MCCL_1749: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA Site: position = -86 score = 71.83 sequence = AATATCACTAGGGGT... Gene: MCCL_0787: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
*
Staphylococcus aureus subsp. aureus N315 Site: position = -183 score = 76.91 sequence = AAGGAACTACTAGGG... Gene: SA1897: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
*
Staphylococcus capitis SK14 Site: position = -177 score = 76.92 sequence = TATTAACTACTAGGG... Gene: STACA0001_0798: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
*
Staphylococcus carnosus subsp. carnosus TM300 Site: position = -165 score = 73.28 sequence = ATAAAATTGCTAGGG... Gene: Sca_1596: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
*
Staphylococcus epidermidis ATCC 12228 Site: position = -171 score = 85.11 sequence = TATTTGCTACTAGGG... Gene: SE1693: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
*
Staphylococcus haemolyticus JCSC1435 Site: position = -177 score = 84.11 sequence = AATGCTACTAGGGGA... Gene: SH0940: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -175 score = 83.55 sequence = AACGCTACTAGGGGA... Gene: SSP0789: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
| thiD |
Gene: MCCL_1748: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: SA1896: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: STACA0001_0797: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: Sca_1595: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: SE1692: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: SH0941: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: SSP0790: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
| thiM |
Gene: MCCL_1747: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: SA1895: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: STACA0001_0796: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: Sca_1594: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: SE1691: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: SH0942: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: SSP0791: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Hydroxyethylthiazole kinase (EC 2.7.1.50) |
| thiE |
Gene: MCCL_1746: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: SA1894: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: STACA0001_0795: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: Sca_1593: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: SE1690: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: SH0943: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: SSP0792: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
| CRON 7. | ||||||||
| thiY |
*
Macrococcus caseolyticus JCSC5402 Site: position = -132 score = 66.88 sequence = TTAAACACTAGGGGA... Gene: MCCL_0880: Hydroxymethylpyrimidine ABC transporter, substrate-binding component |
|
|
|
*
Staphylococcus epidermidis ATCC 12228 Site: position = -159 score = 67.31 sequence = CTAGTATCACTAGGG... Gene: SE0251: Hydroxymethylpyrimidine ABC transporter, substrate-binding component |
*
Staphylococcus haemolyticus JCSC1435 Site: position = -161 score = 70.96 sequence = AAAAAATCACTAGGG... Gene: SH0246: Hydroxymethylpyrimidine ABC transporter, substrate-binding component |
|
Hydroxymethylpyrimidine ABC transporter, substrate-binding component |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |