Regulog TrpR - Vibrionales

Properties
Regulator type:	Transcription factor
Regulator family:	TrpR
Regulation mode:	repressor
Biological process:	Tryptophan biosynthesis
Effector:	Tryptophan
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 24 sites [see more]

Member of regulog collections

By trascription factor - TrpR
By taxonomy - Vibrionales
By TF family - TrpR
By effector - Tryptophan
By pathway - Tryptophan biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Vibrio angustum S14	9	3
Vibrio cholerae O1 biovar eltor str. N16961	7	2
Vibrio fischeri ES114	8	2
Vibrio harveyi ATCC BAA-1116	7	2
Vibrio parahaemolyticus RIMD 2210633	8	3
Vibrio salmonicida LFI1238	7	2
Vibrio shilonii AK1	8	3
Vibrio splendidus LGP32	7	2
Vibrio vulnificus CMCP6	9	3
Photobacterium profundum SS9	8	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes											Function

CRON 1.
tnaA	Vibrio angustum S14	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VCA0161: Tryptophanase (EC 4.1.99.1)	Vibrio fischeri ES114	Vibrio harveyi ATCC BAA-1116	Vibrio parahaemolyticus RIMD 2210633	Vibrio salmonicida LFI1238	Vibrio shilonii AK1 Gene: VSAK1_05975: Tryptophanase (EC 4.1.99.1)	Vibrio splendidus LGP32	* Vibrio vulnificus CMCP6 Site: position = -192 score = 5.50843 sequence = CATACTAGTTTATTAGTACA Gene: VV20854: Tryptophanase (EC 4.1.99.1)	Photobacterium profundum SS9	Tryptophanase (EC 4.1.99.1)
tnaB	* Vibrio angustum S14 Site: position = -40 score = 5.81686 sequence = TGTACTAGTTTACTGATACG Gene: VAS14_21046: Tryptophan-specific transport protein	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VCA0160: Tryptophan-specific transport protein	Vibrio fischeri ES114	Vibrio harveyi ATCC BAA-1116	Vibrio parahaemolyticus RIMD 2210633	Vibrio salmonicida LFI1238	Vibrio shilonii AK1 Gene: VSAK1_05970: Tryptophan-specific transport protein	Vibrio splendidus LGP32	Vibrio vulnificus CMCP6 Gene: VV20855: Tryptophan-specific transport protein	Photobacterium profundum SS9 Gene: PBPRA2533: Tryptophan-specific transport protein	Tryptophan-specific transport protein

CRON 2.
COG0733	Vibrio angustum S14	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -41 score = 6.11045 sequence = TGTACTAGTTAACTAGTGTG Gene: VC2283: Predicted tryptophan transporter, SNF family	* Vibrio fischeri ES114 Site: position = -25 score = 5.41132 sequence = TGTACTAGTTGAGTGATACA Gene: VF_0660: Predicted tryptophan transporter, SNF family	* Vibrio harveyi ATCC BAA-1116 Site: position = -41 score = 6.00492 sequence = TGTACTAGTCAGCTAGTTCA Gene: VIBHAR_03257: Predicted tryptophan transporter, SNF family	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -41 score = 6.32215 sequence = TGTACTAGTTAGCTAGTTCA Gene: VP2337: Predicted tryptophan transporter, SNF family	* Vibrio salmonicida LFI1238 Site: position = -23 score = 4.81139 sequence = TGTACTAGTGTGGTGATACA Gene: VSAL_I0762: Predicted tryptophan transporter, SNF family	* Vibrio shilonii AK1 Site: position = -22 score = 5.8895 sequence = TGTACCAGCAAACTAGTACG Gene: VSAK1_12140: Predicted tryptophan transporter, SNF family	* Vibrio splendidus LGP32 Site: position = -41 score = 5.46353 sequence = TGTACTTCTCAACTAGTTCA Gene: VS_0706: Predicted tryptophan transporter, SNF family	* Vibrio vulnificus CMCP6 Site: position = -38 score = 6.32215 sequence = TGTACTAGCTAACTAGTTCA Gene: VV1_1834: Predicted tryptophan transporter, SNF family	Photobacterium profundum SS9	Predicted tryptophan transporter, SNF family

CRON 3.
aroA	* Vibrio angustum S14 Site: position = -73 score = 5.11241 sequence = GGTACTAGCTAACTGATGCA Gene: VAS14_18534: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC1732: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	Vibrio fischeri ES114 Gene: VF_1761: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	Vibrio harveyi ATCC BAA-1116 Gene: VIBHAR_01572: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	Vibrio parahaemolyticus RIMD 2210633 Gene: VP1020: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	Vibrio salmonicida LFI1238 Gene: VSAL_I2218: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	* Vibrio shilonii AK1 Site: position = -160 score = 5.08158 sequence = AGTACTAGCTGGCTAGTACT Gene: VSAK1_04012: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	Vibrio splendidus LGP32 Gene: VS_1079: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	Vibrio vulnificus CMCP6 Gene: VV1_2127: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	* Photobacterium profundum SS9 Site: position = -71 score = 4.68459 sequence = GGTACTAGCGAACTGATGCA Gene: PBPRA2452: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)	5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)

CRON 4.
trpE	Vibrio angustum S14 Gene: VAS14_18369: Anthranilate synthase, aminase component (EC 4.1.3.27)	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -294 score = 6.46042 sequence = CGCACTAGTTAACTAGTACG Gene: VC1174: Anthranilate synthase, aminase component (EC 4.1.3.27)	2 Vibrio fischeri ES114* Site: position = -347 score = 6.30686 sequence = CGCACTAGTTTACTAGTACA Gene: VF_2602: Anthranilate synthase, aminase component (EC 4.1.3.27) Gene: VF_1033: Anthranilate synthase, aminase component (EC 4.1.3.27)	* Vibrio harveyi ATCC BAA-1116 Site: position = -351 score = 6.56868 sequence = TGCACTAGTTAACTAGTACA Gene: VIBHAR_02758: Anthranilate synthase, aminase component (EC 4.1.3.27)	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -352 score = 6.46042 sequence = CGCACTAGTTAACTAGTACG Gene: VP1956: Anthranilate synthase, aminase component (EC 4.1.3.27)	* Vibrio salmonicida LFI1238 Site: position = -339 score = 6.25272 sequence = CGCACTAGTTTACTAGTACG Gene: VSAL_I1154: Anthranilate synthase, aminase component (EC 4.1.3.27)	* Vibrio shilonii AK1 Site: position = -333 score = 6.49556 sequence = CGAACTAGTTAACTAGTACG Gene: VSAK1_01022: Anthranilate synthase, aminase component (EC 4.1.3.27)	* Vibrio splendidus LGP32 Site: position = -317 score = 5.80691 sequence = AAAACTAGTTAACTAGTACA Gene: VS_1966: Anthranilate synthase, aminase component (EC 4.1.3.27)	* Vibrio vulnificus CMCP6 Site: position = -355 score = 6.56868 sequence = TGCACTAGTTAACTAGTACA Gene: VV1_3064: Anthranilate synthase, aminase component (EC 4.1.3.27)	Photobacterium profundum SS9 Gene: PBPRA2486: Anthranilate synthase, aminase component (EC 4.1.3.27)	Anthranilate synthase, aminase component (EC 4.1.3.27)
trpD_a	Vibrio angustum S14 Gene: VAS14_18364: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC1173: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Vibrio fischeri ES114 Gene: VF_1032: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Vibrio harveyi ATCC BAA-1116 Gene: VIBHAR_02759: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Vibrio parahaemolyticus RIMD 2210633 Gene: VP1957: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Vibrio salmonicida LFI1238 Gene: VSAL_I1153: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Vibrio shilonii AK1 Gene: VSAK1_01017: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Vibrio splendidus LGP32 Gene: VS_1967: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Vibrio vulnificus CMCP6 Gene: VV1_3065: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Photobacterium profundum SS9 Gene: PBPRA2487: Anthranilate synthase, amidotransferase component (EC 4.1.3.27)	Anthranilate synthase, amidotransferase component (EC 4.1.3.27)
trpD_b	Vibrio angustum S14 Gene: VAS14_18359: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC1172: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Vibrio fischeri ES114 Gene: VF_1031: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Vibrio harveyi ATCC BAA-1116 Gene: VIBHAR_02760: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Vibrio parahaemolyticus RIMD 2210633 Gene: VP1958: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Vibrio salmonicida LFI1238 Gene: VSAL_I1152: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Vibrio shilonii AK1 Gene: VSAK1_01012: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Vibrio splendidus LGP32 Gene: VS_1968: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Vibrio vulnificus CMCP6 Gene: VV1_3066: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Photobacterium profundum SS9 Gene: PBPRA2488: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Anthranilate phosphoribosyltransferase (EC 2.4.2.18)
trpC	Vibrio angustum S14 Gene: VAS14_18354: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC1171: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Vibrio fischeri ES114 Gene: VF_1029: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Vibrio harveyi ATCC BAA-1116 Gene: VIBHAR_02761: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Vibrio parahaemolyticus RIMD 2210633 Gene: VP1959: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Vibrio salmonicida LFI1238 Gene: VSAL_I1151: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Vibrio shilonii AK1 Gene: VSAK1_01007: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Vibrio splendidus LGP32 Gene: VS_1969: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Vibrio vulnificus CMCP6 Gene: VV1_3067: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Photobacterium profundum SS9 Gene: PBPRA2489: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)
trpB	Vibrio angustum S14 Gene: VAS14_18349: Tryptophan synthase beta chain (EC 4.2.1.20)	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC1170: Tryptophan synthase beta chain (EC 4.2.1.20)	Vibrio fischeri ES114 Gene: VF_1028: Tryptophan synthase beta chain (EC 4.2.1.20)	Vibrio harveyi ATCC BAA-1116 Gene: VIBHAR_02762: Tryptophan synthase beta chain (EC 4.2.1.20)	Vibrio parahaemolyticus RIMD 2210633 Gene: VP1960: Tryptophan synthase beta chain (EC 4.2.1.20)	Vibrio salmonicida LFI1238 Gene: VSAL_I1150: Tryptophan synthase beta chain (EC 4.2.1.20)	Vibrio shilonii AK1 Gene: VSAK1_01002: Tryptophan synthase beta chain (EC 4.2.1.20)	Vibrio splendidus LGP32 Gene: VS_1970: Tryptophan synthase beta chain (EC 4.2.1.20)	Vibrio vulnificus CMCP6 Gene: VV1_3068: Tryptophan synthase beta chain (EC 4.2.1.20)	Photobacterium profundum SS9 Gene: PBPRA2490: Tryptophan synthase beta chain (EC 4.2.1.20)	Tryptophan synthase beta chain (EC 4.2.1.20)
trpA	Vibrio angustum S14 Gene: VAS14_18344: Tryptophan synthase alpha chain (EC 4.2.1.20)	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC1169: Tryptophan synthase alpha chain (EC 4.2.1.20)	Vibrio fischeri ES114 Gene: VF_1027: Tryptophan synthase alpha chain (EC 4.2.1.20)	Vibrio harveyi ATCC BAA-1116 Gene: VIBHAR_02763: Tryptophan synthase alpha chain (EC 4.2.1.20)	Vibrio parahaemolyticus RIMD 2210633 Gene: VP1961: Tryptophan synthase alpha chain (EC 4.2.1.20)	Vibrio salmonicida LFI1238 Gene: VSAL_I1149: Tryptophan synthase alpha chain (EC 4.2.1.20)	Vibrio shilonii AK1 Gene: VSAK1_00997: Tryptophan synthase alpha chain (EC 4.2.1.20)	Vibrio splendidus LGP32 Gene: VS_1971: Tryptophan synthase alpha chain (EC 4.2.1.20)	Vibrio vulnificus CMCP6 Gene: VV1_3069: Tryptophan synthase alpha chain (EC 4.2.1.20)	Photobacterium profundum SS9 Gene: PBPRA2491: Tryptophan synthase alpha chain (EC 4.2.1.20)	Tryptophan synthase alpha chain (EC 4.2.1.20)
aroF2	* Vibrio angustum S14 Site: position = -322 score = 6.342 sequence = TGAACTAGTTTACTAGTACG Gene: VAS14_18374: 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (EC 2.5.1.54)	Vibrio cholerae O1 biovar eltor str. N16961	Vibrio fischeri ES114	Vibrio harveyi ATCC BAA-1116	Vibrio parahaemolyticus RIMD 2210633	Vibrio salmonicida LFI1238	Vibrio shilonii AK1	Vibrio splendidus LGP32	Vibrio vulnificus CMCP6	* Photobacterium profundum SS9 Site: position = -274 score = 6.28786 sequence = CGAACTAGTTTACTAGTACG Gene: PBPRA2485: 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (EC 2.5.1.54)	2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (EC 2.5.1.54)

CRON 5.
trpB2	Vibrio angustum S14	Vibrio cholerae O1 biovar eltor str. N16961	Vibrio fischeri ES114	Vibrio harveyi ATCC BAA-1116	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -116 score = 6.08899 sequence = CGTACTATTTAACTAGTTCA Gene: VPA0585: Tryptophan synthase beta chain like (EC 4.2.1.20)	Vibrio salmonicida LFI1238	Vibrio shilonii AK1 Gene: VSAK1_17077: Tryptophan synthase beta chain like (EC 4.2.1.20)	Vibrio splendidus LGP32	Vibrio vulnificus CMCP6	Photobacterium profundum SS9	Tryptophan synthase beta chain like (EC 4.2.1.20)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog TrpR - Vibrionales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --