Regulog GntR - Enterobacteriales

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	repressor
Biological process:	Gluconate utilization
Effector:	Gluconate
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 61 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - GntR
By TF family - LacI
By effector - Gluconate
By pathway - Gluconate utilization

Statistics of regulated genes
Genome	Genes	Operons
Escherichia coli str. K-12 substr. MG1655	10	5
Salmonella typhimurium LT2	10	5
Citrobacter koseri ATCC BAA-895	8	4
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	5	3
Enterobacter sp. 638	5	3
Erwinia amylovora ATCC 49946	5	2
Yersinia pestis KIM	3	3
Serratia proteamaculans 568	12	5
Erwinia carotovora subsp. atroseptica SCRI1043	5	5
Edwardsiella tarda EIB202	2	1
Proteus mirabilis HI4320	4	2
Photorhabdus luminescens subsp. laumondii TTO1	2	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
gadA	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_02084: Gluconate 2-dehydrogenase subunit (EC 1.1.99.3)	Enterobacter sp. 638	* Erwinia amylovora ATCC 49946 Site: position = -133 score = 5.80241 sequence = TATTGTTACCGGTAACAGTC Gene: EAM_0336: Gluconate 2-dehydrogenase subunit (EC 1.1.99.3)	Yersinia pestis KIM	* Serratia proteamaculans 568 Site: position = -131 score = 5.93391 sequence = ATAAGTTACCGGTAACATTG Gene: Spro_2136: Gluconate 2-dehydrogenase subunit (EC 1.1.99.3)	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Gluconate 2-dehydrogenase subunit (EC 1.1.99.3)
gadB	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_02083: Gluconate 2-dehydrogenase, flavoprotein subunit (EC 1.1.99.3)	Enterobacter sp. 638	Erwinia amylovora ATCC 49946 Gene: EAM_0337: Gluconate 2-dehydrogenase, flavoprotein subunit (EC 1.1.99.3)	Yersinia pestis KIM	Serratia proteamaculans 568 Gene: Spro_2137: Gluconate 2-dehydrogenase, flavoprotein subunit (EC 1.1.99.3)	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Gluconate 2-dehydrogenase, flavoprotein subunit (EC 1.1.99.3)
gadC	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_02082: Gluconate 2-dehydrogenase, cytochrome C subunit (EC 1.1.99.3)	Enterobacter sp. 638	Erwinia amylovora ATCC 49946 Gene: EAM_0338: Gluconate 2-dehydrogenase, cytochrome C subunit (EC 1.1.99.3)	Yersinia pestis KIM	Serratia proteamaculans 568 Gene: Spro_2138: Gluconate 2-dehydrogenase, cytochrome C subunit (EC 1.1.99.3)	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Gluconate 2-dehydrogenase, cytochrome C subunit (EC 1.1.99.3)

CRON 2.
gntK	* Escherichia coli str. K-12 substr. MG1655 Site: position = -48 score = 5.76626 sequence = AACAGTTACCCGTAACATTT Site: position = -61 score = 6.36966 sequence = CAATGTTACCGATAACAGTT Gene: b3437: Thermoresistant gluconokinase (EC 2.7.1.12)	* Salmonella typhimurium LT2 Site: position = -48 score = 5.1261 sequence = AACAGTTACCCGTAACAAAT Site: position = -61 score = 6.36966 sequence = CAATGTTACCGATAACAGTT Gene: STM3542: Thermoresistant gluconokinase (EC 2.7.1.12)	* Citrobacter koseri ATCC BAA-895 Site: position = -101 score = 6.36966 sequence = CAATGTTACCGATAACAGTT Site: position = -88 score = 5.6094 sequence = AACAGTTACCCGTAACAATT Gene: CKO_04856: Thermoresistant gluconokinase (EC 2.7.1.12)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -58 score = 6.36966 sequence = CAATGTTACCGATAACAGTT Site: position = -45 score = 5.6094 sequence = AACAGTTACCCGTAACAATT Gene: KPN_03801: Thermoresistant gluconokinase (EC 2.7.1.12)	* Enterobacter sp. 638 Site: position = -49 score = 5.77929 sequence = CAATGTTACCGATAACTGTT Site: position = -36 score = 6.00818 sequence = AACTGTTACCCGTAACAATT Gene: Ent638_3845: Thermoresistant gluconokinase (EC 2.7.1.12)	* Erwinia amylovora ATCC 49946 Site: position = -59 score = 5.85384 sequence = CAATGTTACCGATAACAACG Gene: EAM_3275: Thermoresistant gluconokinase (EC 2.7.1.12)	* Yersinia pestis KIM Site: position = -91 score = 5.63222 sequence = ATTTGTTACCGGTATCATGA Site: position = -77 score = 5.53916 sequence = TCATGATACCGGTAACATGG Gene: y3876: Thermoresistant gluconokinase (EC 2.7.1.12)	2 Serratia proteamaculans 568* Gene: Spro_4650: Thermoresistant gluconokinase (EC 2.7.1.12) Site: position = -73 score = 6.43468 sequence = CAATGTTACCGATAACATGT Site: position = -59 score = 5.50156 sequence = ACATGTTACCGGTAACAAAC Gene: Spro_4497: Thermoresistant gluconokinase (EC 2.7.1.12)	2 Erwinia carotovora subsp. atroseptica SCRI1043* Site: position = -91 score = 5.44127 sequence = ACTTGTTACCGGTATCATGA Site: position = -77 score = 5.08722 sequence = TCATGATACCGGTAACGTGA Gene: ECA1839: Thermoresistant gluconokinase (EC 2.7.1.12) Site: position = -77 score = 5.27232 sequence = ATATGATACGGGTAACATGT Gene: ECA4159: Thermoresistant gluconokinase (EC 2.7.1.12)	* Edwardsiella tarda EIB202 Site: position = -58 score = 5.4073 sequence = AACAGTTACCAGTAACATTG Site: position = -71 score = 5.993 sequence = GAATGTTACCCATAACAGTT Gene: ETAE_0135: Thermoresistant gluconokinase (EC 2.7.1.12)	* Proteus mirabilis HI4320 Site: position = -67 score = 6.38587 sequence = TAATGTTACCCGTAACAGTT Site: position = -54 score = 5.29657 sequence = AACAGTTACGGGTAACATTA Gene: PMI2673: Thermoresistant gluconokinase (EC 2.7.1.12)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -52 score = 5.91652 sequence = AACAGTTACCGGTAACATTT Site: position = -65 score = 6.36966 sequence = TAATGTTACCGATAACAGTT Gene: plu0497: Thermoresistant gluconokinase (EC 2.7.1.12)	Thermoresistant gluconokinase (EC 2.7.1.12)
gntU	Escherichia coli str. K-12 substr. MG1655 Gene: b4476: Low-affinity gluconate transporter	Salmonella typhimurium LT2 Gene: STM3541: Low-affinity gluconate transporter	Citrobacter koseri ATCC BAA-895 Gene: CKO_04855: Low-affinity gluconate transporter	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03800: Low-affinity gluconate transporter	Enterobacter sp. 638 Gene: Ent638_3844: Low-affinity gluconate transporter	Erwinia amylovora ATCC 49946 Gene: EAM_3274: Low-affinity gluconate transporter	Yersinia pestis KIM	Serratia proteamaculans 568 Gene: Spro_4498: Low-affinity gluconate transporter	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -100 score = 5.45063 sequence = ACATGTTACCCGTATCATAT Gene: ECA4158: Low-affinity gluconate transporter	Edwardsiella tarda EIB202 Gene: ETAE_0134: Low-affinity gluconate transporter	Proteus mirabilis HI4320 Gene: PMI2672: Low-affinity gluconate transporter	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu0498: Low-affinity gluconate transporter	Low-affinity gluconate transporter
edd	* Escherichia coli str. K-12 substr. MG1655 Site: position = -212 score = 6.29244 sequence = TTATTTTACCGGTAACATGA Gene: b1851: 6-phosphogluconate dehydratase (EC 4.2.1.12)	* Salmonella typhimurium LT2 Site: position = -212 score = 6.06605 sequence = GTATTTTACCGGTAACATGA Gene: STM1885: 6-phosphogluconate dehydratase (EC 4.2.1.12)	* Citrobacter koseri ATCC BAA-895 Site: position = -211 score = 6.29244 sequence = TTATTTTACCGGTAACATGA Gene: CKO_01115: 6-phosphogluconate dehydratase (EC 4.2.1.12)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -211 score = 6.29244 sequence = TTATTTTACCGGTAACATGA Site: position = -2 score = 5.41825 sequence = CAATGTTACGGGTAACAAAT Gene: KPN_02366: 6-phosphogluconate dehydratase (EC 4.2.1.12)	* Enterobacter sp. 638 Site: position = -210 score = 6.29244 sequence = TTATTTTACCGGTAACATGA Gene: Ent638_2420: 6-phosphogluconate dehydratase (EC 4.2.1.12)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y1654: 6-phosphogluconate dehydratase (EC 4.2.1.12)	Serratia proteamaculans 568 Gene: Spro_4499: 6-phosphogluconate dehydratase (EC 4.2.1.12)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -359 score = 5.85753 sequence = CATTGTTACCGGTATCATTT Gene: ECA1836: 6-phosphogluconate dehydratase (EC 4.2.1.12)	Edwardsiella tarda EIB202 Gene: ETAE_1451: 6-phosphogluconate dehydratase (EC 4.2.1.12)	* Proteus mirabilis HI4320 Site: position = -111 score = 5.07794 sequence = GCTTGTTACCCGTAACAATG Site: position = -96 score = 6.44429 sequence = CAATGTTACCGGTAACAAGT Gene: PMI2760: 6-phosphogluconate dehydratase (EC 4.2.1.12)	Photorhabdus luminescens subsp. laumondii TTO1	6-phosphogluconate dehydratase (EC 4.2.1.12)
eda	Escherichia coli str. K-12 substr. MG1655 Gene: b1850: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Salmonella typhimurium LT2 Gene: STM1884: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Citrobacter koseri ATCC BAA-895 Gene: CKO_01116: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_02365: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Enterobacter sp. 638 Gene: Ent638_2419: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y2243: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	2 Serratia proteamaculans 568 Gene: Spro_2767: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14) Gene: Spro_4500: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA2478: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Edwardsiella tarda EIB202 Gene: ETAE_1452: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Proteus mirabilis HI4320 Gene: PMI2761: 2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)	Photorhabdus luminescens subsp. laumondii TTO1	2-keto-3-deoxygluconate 6-phosphate aldolase (EC 4.1.2.14)
gntT	* Escherichia coli str. K-12 substr. MG1655 Site: position = -178 score = 5.8539 sequence = AGATGTTACCCGTATCATTC Site: position = -37 score = 4.89779 sequence = TGACGTTACCCATAACAAAT Gene: b3415: High-affinity H+/gluconate symporter	* Salmonella typhimurium LT2 Site: position = -178 score = 5.95688 sequence = ATATGTTACCCGTATCATTC Site: position = -37 score = 4.72978 sequence = TGACGTTACCCATAACAAAG Gene: STM3512: High-affinity H+/gluconate symporter	* Citrobacter koseri ATCC BAA-895 Site: position = -178 score = 5.95688 sequence = ATATGTTACCCGTATCATTC Site: position = -37 score = 4.89779 sequence = CGACGTTACCCATAACAAAT Gene: CKO_04836: High-affinity H+/gluconate symporter	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -180 score = 5.46231 sequence = ACATGTTACCCGTATCATCC Site: position = -36 score = 4.89779 sequence = TGACGTTACCCATAACAAAT Gene: KPN_03785: High-affinity H+/gluconate symporter	* Enterobacter sp. 638 Site: position = -178 score = 5.8539 sequence = AGATGTTACCCGTATCATTC Site: position = -37 score = 4.89779 sequence = TGACGTTACCCATAACAAAT Gene: Ent638_3828: High-affinity H+/gluconate symporter	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -159 score = 6.04242 sequence = CCATGTTACCGGTATCATGA Site: position = -145 score = 5.11464 sequence = TCATGATACCGGTAACAAAT Gene: y3875: High-affinity H+/gluconate symporter	* Serratia proteamaculans 568 Site: position = -185 score = 5.33828 sequence = GGTTGTTACCGGTATCATGA Site: position = -171 score = 5.42993 sequence = TCATGATACCGGTAACAATG Gene: Spro_4651: High-affinity H+/gluconate symporter	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -239 score = 5.46395 sequence = TCACGTTACCGGTATCATGA Site: position = -225 score = 5.55031 sequence = TCATGATACCGGTAACAAGT Gene: ECA1840: High-affinity H+/gluconate symporter	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	High-affinity H+/gluconate symporter

CRON 3.
sdxX	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -237 score = 5.71908 sequence = TCACGTTACCGGTAACATGT Gene: y1651: putative 2-ketogluconate dehydrogenase	Serratia proteamaculans 568 Gene: Spro_2497: putative 2-ketogluconate dehydrogenase	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	putative 2-ketogluconate dehydrogenase

CRON 4.
idnD	* Escherichia coli str. K-12 substr. MG1655 Site: position = -146 score = 3.82217 sequence = TAtTtcTACtGaTAAgAaTT Site: position = -116 score = 3.7844 sequence = TcAcGTTAtgcGTAACATag Gene: b4267: L-idonate 5-dehydrogenase (EC 1.1.1.264)	* Salmonella typhimurium LT2 Site: position = -116 score = 4.2677 sequence = TcAcGTTAtgcGTAACATTg Gene: STM4484: L-idonate 5-dehydrogenase (EC 1.1.1.264)	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568 Gene: Spro_3287: L-idonate 5-dehydrogenase (EC 1.1.1.264)	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	L-idonate 5-dehydrogenase (EC 1.1.1.264)
idnO	Escherichia coli str. K-12 substr. MG1655 Gene: b4266: Gluconate 5-dehydrogenase (EC 1.1.1.69)	Salmonella typhimurium LT2 Gene: STM4483: Gluconate 5-dehydrogenase (EC 1.1.1.69)	* Citrobacter koseri ATCC BAA-895 Site: position = -39 score = 4.79507 sequence = TACAGTTACGCGTAACAGCT Gene: CKO_02793: Gluconate 5-dehydrogenase (EC 1.1.1.69)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y1645: Gluconate 5-dehydrogenase (EC 1.1.1.69)	* Serratia proteamaculans 568 Site: position = -120 score = 4.1697 sequence = TcAcGTTAaaGGTAACAgcT Gene: Spro_3288: Gluconate 5-dehydrogenase (EC 1.1.1.69)	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Gluconate 5-dehydrogenase (EC 1.1.1.69)
idnT	Escherichia coli str. K-12 substr. MG1655 Gene: b4265: L-idonate and D-gluconate transporter	Salmonella typhimurium LT2 Gene: STM4482: L-idonate and D-gluconate transporter	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	L-idonate and D-gluconate transporter
idnR	Escherichia coli str. K-12 substr. MG1655 Gene: b4264: L-idonate utilization transcriptional regulator IdnR, LacI family	Salmonella typhimurium LT2 Gene: STM4481: L-idonate utilization transcriptional regulator IdnR, LacI family	Citrobacter koseri ATCC BAA-895 Gene: CKO_02791: L-idonate utilization transcriptional regulator IdnR, LacI family	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y1650: L-idonate utilization transcriptional regulator IdnR, LacI family	* Serratia proteamaculans 568 Site: position = -169 score = 4.37405 sequence = AGCTGTTACCTTTAACGTGA Gene: Spro_3289: L-idonate utilization transcriptional regulator IdnR, LacI family	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	L-idonate utilization transcriptional regulator IdnR, LacI family
uhpC	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895 Gene: CKO_02792: Predicted sugar-phosphate permease	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Predicted sugar-phosphate permease
idnK	* Escherichia coli str. K-12 substr. MG1655 Site: position = -119 score = 4.96145 sequence = CTATGTTACGCATAACGTGA Gene: b4268: Thermoresistant gluconokinase (EC 2.7.1.12)	* Salmonella typhimurium LT2 Site: position = -119 score = 5.0741 sequence = CAATGTTACGCATAACGTGA Gene: STM4485: Thermoresistant gluconokinase (EC 2.7.1.12)	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y1646: Thermoresistant gluconokinase (EC 2.7.1.12)	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Thermoresistant gluconokinase (EC 2.7.1.12)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog GntR - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --