Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Streptococcus mutans UA159

Type Regulator Effector Pathway Genes Sites
TF AdcR Zinc ion, (Zn2+) Zinc homeostasis 2 3
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 4 13
TF BirA Biotin Biotin biosynthesis 1 1
TF CcpA Fructose-1,6-bisphosphate; HPr, phosphocarrier protein Global catabolite repression 61 80
TF CelR CelB, cellobiose-specific PTS component EIIB; HPr, phosphocarrier protein Cellobiose utilization 1 1
TF CmbR O-acetyl-L-serine Cysteine metabolism 10 16
TF CodY Guanosine triphosphate; Branched-chain amino acids Amino acid metabolism 23 25
TF CopR Copper ion, (Cu2+) Copper homeostasis 1 2
TF CtsR Heat shock Heat shock response 3 3
TF FabT Long-chain acyl-ACP Fatty acid biosynthesis 4 5
TF FruR Fructose-6-phosphate Fructose utilization 1 2
TF GalR Galactose Galactose utilization 2 4
TF GlnR Phosphorylated NtrB, signal histidine kinase Nitrogen assimilation 6 7
TF GutR HPr, phosphocarrier protein; GutB, sorbitol-specific PTS EIIB component Sorbitol utilization 1 1
TF HomR O-acetyl-L-serine Methionine metabolism; Cysteine metabolism 5 7
TF HrcA Heat shock Heat shock response 2 3
TF LacR D-galactose-6-phosphate Lactose utilization; Galactose utilization 1 3
TF MalR Maltose Maltose utilization; Maltodextrin utilization 4 4
TF MleR L-malate Malate utilization 1 1
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 1 1
TF MtaR Homocysteine Methionine metabolism 8 11
TF MtlR MtlA, mannitol-specific enzyme IICB PTS component; HPr, phosphocarrier protein Mannitol utilization 1 1
TF NagR N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 3 4
TF NiaR Niacin NAD biosynthesis 1 1
TF NmlR Methylglyoxal; Formaldehyde; Nitric oxide Carbonyl stress response 2 2
TF NrdR Deoxyribonucleotides Deoxyribonucleotide biosynthesis 2 3
TF NigR Nigerose-6-phosphate Nigerose utilization 1 1
TF PerR Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide Iron homeostasis; Manganese homeostasis; Oxidative stress response 8 9
TF PflR Formate metabolism 3 3
TF PipR Phage infection protein 2 4
TF PurR 5-phosphoribosyl 1-pyrophosphate Purine metabolism 7 9
TF Rex NADH Energy metabolism 12 23
TF SAG1910 unknown 3 3
TF ScrR Sucrose-6-phosphate Sucrose utilization 2 2
TF SgaR HPr, phosphocarrier protein; SgaB, ascorbate-specific PTS system EIIB component Ascorbate utilization 2 2
TF SPy1285 Transport 2 2
TF TagR Tagatose-6-phosphate Tagatose utilization 2 2
TF TreR Trehalose-6-phosphate Trehalose utilization 2 2
TF YjdR Multidrug resistance 1 1
TF YwzG Transport 1 1
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