Propagation of PerR regulog to Streptococcus mutans UA159
| Source regulog: | PerR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | FUR |
| Regulation mode: | repressor |
| Biological process: | Iron homeostasis; Manganese homeostasis; Oxidative stress response |
| Effector: | Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus mutans UA159 |
| Orthologous TF(s) | SMU.593, SMU.70 |
| Regulated genes | 8 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -26
Score: 4.8 Sequence: TTATATTACTTATAA
Locus tag: SMU.182
|
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| SMU.182 | -26 | 4.8 | TTATATTACTTATAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: mntC | ||||
| Ortholog function: Manganese ABC transporter, ATP-binding protein | ||||
| Streptococcus agalactiae 2603V/R | SAG1532 | -28 | 5.1 | TTATATTAATTTTAA |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0489 | -124 | 5.6 | TTATAATCATTATTA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1468 | -124 | 5.6 | TTATAATGATTATTA |
| Streptococcus gallolyticus UCN34 | GALLO_2046 | -66 | 4.8 | TTATATTAAATATAA |
| Streptococcus mutans UA159 | SMU.182 | -26 | 4.8 | TTATATTACTTATAA |
| Streptococcus pyogenes M1 GAS | SPy0454 | -124 | 5.6 | TTATAATGATTATTA |
| Streptococcus sanguinis SK36 | SSA_0262 | -54 | 4.4 | TTATATTAATTTTAG |
| Streptococcus uberis 0140J | SUB0474 | -123 | 5.6 | TTATAATCATTATTA |
|
Position: -57
Score: 5.5 Sequence: TTAGAATCGTTCTAA
Locus tag: SMU.540
|
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| SMU.540 | -57 | 5.5 | TTAGAATCGTTCTAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: mgrA | ||||
| Ortholog function: Non-specific DNA-binding protein / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1) | ||||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1517 | -148 | 4.7 | CGAGAATGATTCTAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0585 | -136 | 4.7 | CGAGAATGATTCTAA |
| Streptococcus gallolyticus UCN34 | GALLO_0592 | -76 | 5.8 | TTAGAATTATTCTAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0665 | -73 | 5.3 | TTAGAAGCATTATAA |
| -37 | 5.9 | TTAGAATGATTATAA | ||
| Streptococcus mutans UA159 | SMU.540 | -57 | 5.5 | TTAGAATCGTTCTAA |
| Streptococcus pyogenes M1 GAS | SPy1531 | -157 | 4.7 | CGATAATGATTCTAA |
| Streptococcus sanguinis SK36 | SSA_0644 | -71 | 5.3 | TTAGAAGCATTATAA |
| -35 | 5.9 | TTAGAATCATTATAA | ||
| Streptococcus suis 05ZYH33 | SSU05_1689 | -34 | 5.9 | TTATAATTATTATAA |
| Streptococcus thermophilus CNRZ1066 | str0723 | -59 | 5.2 | TTATAAATATTTTAA |
|
Position: -118
Score: 4.8 Sequence: TTATAATGTTTCTCA
Locus tag: SMU.569
|
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| SMU.569 | -118 | 4.8 | TTATAATGTTTCTCA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: feoA | ||||
| Ortholog function: Ferrous iron transport protein A | ||||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1493 | -105 | 5.6 | TTAGAATCATTATTA |
| Streptococcus gallolyticus UCN34 | GALLO_0619 | -167 | 5.9 | TTATAATGATTCTAA |
| -135 | 5 | TTAGAACAATTCTAA | ||
| Streptococcus mutans UA159 | SMU.569 | -118 | 4.8 | TTATAATGTTTCTCA |
|
Position: -157
Score: 4.7 Sequence: TTTGAATGATTTTTA
Locus tag: SMU.593
|
||||
| SMU.593 | -157 | 4.7 | TTTGAATGATTTTTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: perR | ||||
| Ortholog function: Peroxide stress response transcriptional regulator PerR, Fur family | ||||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0703 | -74 | 5 | TTACAATCATTCTTA |
| Streptococcus mutans UA159 | SMU.593 | -157 | 4.7 | TTTGAATGATTTTTA |
| Streptococcus sanguinis SK36 | SSA_0686 | -83 | 5 | TTACAATCATTCTTA |
| Streptococcus suis 05ZYH33 | SSU05_0310 | -38 | 5.4 | TTAGAATTTTTATAA |
| Streptococcus thermophilus CNRZ1066 | str0724 | -59 | 5.2 | TTATAAATATTTTAA |
|
Position: -37
Score: 5.4 Sequence: TTGTAATCATTCTAA
Locus tag: SMU.635
|
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| SMU.635 | -37 | 5.4 | TTGTAATCATTCTAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: pcl | ||||
| Ortholog function: Predicted membrane protein | ||||
| Streptococcus agalactiae 2603V/R | SAG0798 | -79 | 5.9 | TTAGAATGATTATAA |
| -57 | 5.4 | TTGTAATCATTCTAA | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1772 | -41 | 5.9 | TTATAATGATTATAA |
| Streptococcus mutans UA159 | SMU.635 | -37 | 5.4 | TTGTAATCATTCTAA |
| Streptococcus sanguinis SK36 | SSA_0299 | -227 | 5.9 | TTATAATCATTATAA |
| Streptococcus thermophilus CNRZ1066 | str0552 | -65 | 4.9 | TTGTAATCAATCTAA |
| -30 | 5.9 | TTATAATGATTCTAA | ||