Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of CcpA regulog to Streptococcus mutans UA159

Reference regulog properties
Source regulog: CcpA - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LacI
Regulation mode:
Biological process: Global catabolite repression
Effector: Fructose-1,6-bisphosphate; HPr, phosphocarrier protein
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus mutans UA159
Orthologous TF(s) SMU.1591
Regulated genes 61
Built upon 968 sites [see more]
Predicted regulatory interactions in Streptococcus mutans UA159
Locus tag Position Score Sequence
Position: -165
Score: 4.7
Sequence: AAGATAGCGCTTACAA
Locus tag: SMU.78
SMU.78 -165 4.7 AAGATAGCGCTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: sacC
Ortholog function: Fructanase (EC 3.2.1.80) / Levanase (EC 3.2.1.65)
Streptococcus gallolyticus UCN34 GALLO_0112 -84 4.3 ATGATAACGCTTTCTC
Streptococcus mutans UA159 SMU.78 -165 4.7 AAGATAGCGCTTACAA
Streptococcus uberis 0140J SUB0135 -185 4.1 TAATAAACGATTTAAT
-75 4.2 GTGATAACGTTTTCTT
Position: -92
Score: 4.6
Sequence: ATGAAATCCTTTTCAT
Locus tag: SMU.89c
SMU.89c -92 4.6 ATGAAATCCTTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yrhG
Ortholog function: Predicted permease
Streptococcus gordonii str. Challis substr. CH1 SGO_1137 -69 4.3 AAGAAAACGATTTCGT
Streptococcus mitis B6 smi_1009 -68 3.9 CGGAAAACGCTTCCTA
Streptococcus mutans UA159 SMU.89c -92 4.6 ATGAAATCCTTTTCAT
Streptococcus pneumoniae TIGR4 SP_1215 -68 4.3 CAGAAAACGCTTCCTA
Streptococcus sanguinis SK36 SSA_1098 -71 4.8 TAGAAAACGCTATCAA
Position: -161
Score: 4.6
Sequence: ATGAAAAGGATTTCAT
Locus tag: SMU.91
SMU.91 -161 4.6 ATGAAAAGGATTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ropA
Ortholog function: Cell division trigger factor (EC 5.2.1.8)
Streptococcus agalactiae 2603V/R SAG0105 -65 4.2 TGTAAAACGTTTTAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0327 22 4.7 TTAAAAACGCTTTAAA
Streptococcus mutans UA159 SMU.91 -161 4.6 ATGAAAAGGATTTCAT
Streptococcus pneumoniae TIGR4 SP_0400 -53 3.9 TAGAAAATGTTATAAT
Streptococcus pyogenes M1 GAS SPy1896 -65 4.7 TTAAAAACGCTTTAAA
Streptococcus suis 05ZYH33 SSU05_0328 -65 4 TTGAAATCCTTGTCAA
Position: -75
Score: 4.5
Sequence: ATGATAGCACTTTCAT
Locus tag: SMU.112c
SMU.112c -75 4.5 ATGATAGCACTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruR2
Ortholog function: Predicted fructose utilization transcriptional regulator FruR2, RpiR family
Lactococcus lactis subsp. lactis Il1403 L47971 -106 4.5 ATAAAAACGATTTCAG
Streptococcus mutans UA159 SMU.112c -75 4.5 ATGATAGCACTTTCAT
Position: -69
Score: 4.5
Sequence: ATGAAAGTGCTATCAT
Locus tag: SMU.113
SMU.113 -69 4.5 ATGAAAGTGCTATCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruK2
Ortholog function: Fructose-1-phosphate kinase (EC 2.7.1.56)
Streptococcus mutans UA159 SMU.113 -69 4.5 ATGAAAGTGCTATCAT
Position: -51
Score: 4.1
Sequence: TAGAAAGCGGTTCAAA
Locus tag: SMU.127
SMU.127 -51 4.1 TAGAAAGCGGTTCAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: acoA
Ortholog function: Acetoin dehydrogenase E1 component alpha-subunit (EC 1.2.4.-)
Streptococcus agalactiae 2603V/R SAG0878 -81 4.2 AAGAAAGCGGTTCAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1250 -67 4.7 AAGAAAGCGATTTAAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1222 -90 3.9 TTAAAAAAGCTTTTAT
-67 4.5 AAGAAAGCGATTAAAA
Streptococcus gallolyticus UCN34 GALLO_0867 -99 5 TTTAAAACGTTTTCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1133 -63 4.4 TTGACAGGGTTTTCAT
Streptococcus mutans UA159 SMU.127 -51 4.1 TAGAAAGCGGTTCAAA
Streptococcus pyogenes M1 GAS SPy1026 -79 4.7 TAGAAAGCGATTTAAT
Streptococcus sanguinis SK36 SSA_1178 -63 3.8 TTGACAGTGCTTACAG
Streptococcus suis 05ZYH33 SSU05_1841 -36 4.2 AAGAAAACGGTTCAAT
Streptococcus thermophilus CNRZ1066 str1051 -96 4.2 ATGTAAGGCTTTTCAT
Streptococcus uberis 0140J SUB1103 -80 4.6 TAGAAAGCGGTTTTAA
Position: -78
Score: 4.7
Sequence: ATGTAAACGCTTGCTT
Locus tag: SMU.179
SMU.179 -78 4.7 ATGTAAACGCTTGCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yieF
Ortholog function: Predicted NADH-dependent flavin oxidoreductase
Streptococcus gallolyticus UCN34 GALLO_1928 -171 4.6 ATGTCAACGCTTACAT
-73 4.9 ATAAAAACGTTTACAT
Streptococcus mutans UA159 SMU.179 -78 4.7 ATGTAAACGCTTGCTT
Streptococcus uberis 0140J SUB0907 -126 4.3 AAGAAAACGCAAACAT
-72 4.1 ATGAAAACAGTTGCAT
Position: -72
Score: 4.2
Sequence: TTGTTAGCATTTTCAA
Locus tag: SMU.270
SMU.270 -72 4.2 TTGTTAGCATTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: sgaT
Ortholog function: Ascorbate-specific PTS system, IIC component
Streptococcus agalactiae 2603V/R SAG1815 -71 4.9 TTTAAAACGCTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2013 -171 4 TTTAAAGAGTTTTAAA
-75 5.1 TTTAAAACGCTTTCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0168 -76 5 TTTAAAACGCTTACAT
Streptococcus gallolyticus UCN34 GALLO_2127 -71 4.3 TTGTTTGCGCTTACAT
Streptococcus mitis B6 smi_0219 -60 4.4 TTGTTTACGCTTTCAA
Streptococcus mutans UA159 SMU.270 -72 4.2 TTGTTAGCATTTTCAA
Streptococcus pyogenes M1 GAS SPy0174 -81 5.1 TTTAAAACGCTTTCAT
Streptococcus sanguinis SK36 SSA_2093 -70 4.6 TTGTTATCGCTTTCAA
Streptococcus suis 05ZYH33 SSU05_2063 -64 4 TTGTTTCCGCTTACAT
Streptococcus uberis 0140J SUB1727 -76 4.5 TTTAAAACGCTTTCAC
Position: -53
Score: 4.3
Sequence: AAGTAAGCGTTTTATG
Locus tag: SMU.291
SMU.291 -53 4.3 AAGTAAGCGTTTTATG
Supported by regulated orthologs from reference regulons
Ortholog gene name: tkt2
Ortholog function: Transketolase (EC 2.2.1.1)
Streptococcus mutans UA159 SMU.291 -53 4.3 AAGTAAGCGTTTTATG
Position: -85
Score: 4.9
Sequence: ATGAAAGCGTTTTATA
Locus tag: SMU.307
SMU.307 -85 4.9 ATGAAAGCGTTTTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pgi
Ortholog function: Glucose-6-phosphate isomerase (EC 5.3.1.9)
Lactococcus lactis subsp. cremoris SK11 LACR_2470 -148 4 AAATAAGTGCTTACAT
Lactococcus lactis subsp. lactis Il1403 L0012 -148 4.7 AAATAAGCGCTTACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1988 -120 4.8 TTGAAAACCTTTTCAA
-51 4.3 TAGAAAAGGTTATCAT
Streptococcus gallolyticus UCN34 GALLO_2098 -105 4.2 TGGTAAACGCTTTATT
Streptococcus gordonii str. Challis substr. CH1 SGO_0154 -85 4.6 TTGGAAGCGTTTTAAA
-44 3.8 CGTAAAGCGTTATCAT
Streptococcus mitis B6 smi_0157 -44 4 AAGTAAGCGTTATGAT
Streptococcus mutans UA159 SMU.307 -85 4.9 ATGAAAGCGTTTTATA
Streptococcus pyogenes M1 GAS SPy0215 -121 4.2 ACGAAAACCTTTTCAA
-52 4.3 TAGAAAAGGTTATCAT
Streptococcus sanguinis SK36 SSA_2183 -52 4.6 TTGGAAGCGTTTTAAA
-11 4.1 ATGAAAGCGATATGAT
Streptococcus suis 05ZYH33 SSU05_2051 32 3.9 GATAAAGCGTTATCAT
Position: -56
Score: 4.2
Sequence: TTGTGAGCGCTTTATA
Locus tag: SMU.308
SMU.308 -56 4.2 TTGTGAGCGCTTTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: sorD
Ortholog function: Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140)
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0204 -50 4.8 TTGTAAGCGTTTTATA
Streptococcus mutans UA159 SMU.308 -56 4.2 TTGTGAGCGCTTTATA
Streptococcus uberis 0140J SUB1705 -48 4.8 TTGTAAGCGTTTTATA
Position: -30
Score: 4.8
Sequence: ATTAAAACGTTTACTT
Locus tag: SMU.395
SMU.395 -30 4.8 ATTAAAACGTTTACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pepX
Ortholog function: Xaa-Pro dipeptidyl-peptidase
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1909 -39 4.7 ATAAAAACGTTTACTT
Streptococcus gallolyticus UCN34 GALLO_1959 -54 3.8 ATGTAAAGGTTATCTG
-34 4.8 ATTAAAACGTTTACTT
Streptococcus mitis B6 smi_1001 -4 4.1 TTTTATGCGTTTTAAT
Streptococcus mutans UA159 SMU.395 -30 4.8 ATTAAAACGTTTACTT
Streptococcus pyogenes M1 GAS SPy1858 -38 4.2 ATAATATCGTTTTCTA
Streptococcus suis 05ZYH33 SSU05_0197 -4 4.2 ATTTATGCGCTTTAAT
Streptococcus uberis 0140J SUB1574 -37 4.7 ATAAAAACGTTTACTT
Position: -100
Score: 4.8
Sequence: AAGTAAACGTTTTAAT
Locus tag: SMU.396
SMU.396 -100 4.8 AAGTAAACGTTTTAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: glpF2
Ortholog function: Glycerol uptake facilitator protein
Streptococcus agalactiae 2603V/R SAG1732 -182 4 AAGAAAACCTTATAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1908 -103 4.7 AAGTAAACGTTTTTAT
Streptococcus gallolyticus UCN34 GALLO_1958 -103 4.8 AAGTAAACGTTTTAAT
-83 3.8 CAGATAACCTTTACAT
Streptococcus mitis B6 smi_1347 -104 4 ATAAAACCGCTTTCTC
Streptococcus mutans UA159 SMU.396 -100 4.8 AAGTAAACGTTTTAAT
Streptococcus pneumoniae TIGR4 SP_1491 -140 4.9 ATAAAAACGCTTACAA
Streptococcus suis 05ZYH33 SSU05_0268 -24 4.3 GAGTAAACGTTTTCTT
Streptococcus uberis 0140J SUB1573 -101 4.7 AAGTAAACGTTTTTAT
Position: -113
Score: 4.9
Sequence: AAGAAATCGCTTACAA
Locus tag: SMU.402
SMU.402 -113 4.9 AAGAAATCGCTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pfl
Ortholog function: Pyruvate formate-lyase (EC 2.3.1.54)
Lactococcus lactis subsp. cremoris SK11 LACR_0691 -156 5.1 ATGAAAACGTTTTAAA
Lactococcus lactis subsp. lactis Il1403 L57408 -156 5.1 ATGAAAACGTTTTAAA
Streptococcus gallolyticus UCN34 GALLO_1953 -82 4.2 TGGAAAACGCTTCCTT
Streptococcus gordonii str. Challis substr. CH1 SGO_0247 -115 4.6 AAGAAAAGGCTTACAA
-83 4.1 GTGTAAACGATTACTA
Streptococcus mitis B6 smi_1815 -82 4.2 TTGAAATCGGTTACTG
Streptococcus mutans UA159 SMU.402 -113 4.9 AAGAAATCGCTTACAA
Streptococcus pneumoniae TIGR4 SP_0459 -78 4.5 TTGAAATCGGTTACTA
Streptococcus suis 05ZYH33 SSU05_0200 -124 4.1 TTGAAAGGTTTTTCAT
-84 4.6 TAGAAAGTGTTTTCAA
Streptococcus thermophilus CNRZ1066 str1657 -93 4.4 ATGTAAGCGGTTACTG
Position: -58
Score: 4.5
Sequence: ATGAAAGCGATATAAT
Locus tag: SMU.500
SMU.500 -58 4.5 ATGAAAGCGATATAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: raiA
Ortholog function: Ribosome-associated protein Y
Lactococcus lactis subsp. cremoris SK11 LACR_0667 -133 4.4 ATGAAAGCTGTTTCAT
Lactococcus lactis subsp. lactis Il1403 L32389 -133 4.4 ATGAAAGCTGTTTCAT
Streptococcus agalactiae 2603V/R SAG0338 -60 4.6 ATGAAAGCGGTTATAA
-36 4.7 TAGAAAGCGTTAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1681 -64 4.5 ATGAAAGCGGTATAAT
-35 4.2 AAGAAAGCGCTTCAAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1545 -36 4.9 AAGAAAGCGTTTTAAA
Streptococcus gallolyticus UCN34 GALLO_0504 -59 3.8 ATGAAAGCAGTATAAT
-34 4.8 AAGAAAGCGCTTTATA
Streptococcus gordonii str. Challis substr. CH1 SGO_0610 -63 4.7 ATGAAAGCGTTATAAT
Streptococcus mitis B6 smi_2056 -57 4.7 ATGAAAGCGTTATAAT
Streptococcus mutans UA159 SMU.500 -58 4.5 ATGAAAGCGATATAAT
Streptococcus pneumoniae TIGR4 SP_2206 -57 4.7 ATGAAAGCGTTATAAT
Streptococcus pyogenes M1 GAS SPy1613 -64 3.8 ATGAAAGCAGTATAAT
-35 4 AAGTAAGCGCTTCAAG
Streptococcus sanguinis SK36 SSA_1834 -60 4.7 ATGAAAGCGTTATAAT
Streptococcus suis 05ZYH33 SSU05_0439 -42 4.5 AAGAAAACGGTTGCAA
Streptococcus thermophilus CNRZ1066 str0370 -57 3.9 ATGAAAAGGATATAAT
-34 4.7 AAGAAAACGCTAACAA
Streptococcus uberis 0140J SUB1375 -59 4.4 ATGAAAACGGTATAAT
Position: -58
Score: 3.9
Sequence: AGGCAAGCGCTTGCAA
Locus tag: SMU.541
SMU.541 -58 3.9 AGGCAAGCGCTTGCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: yvaA
Ortholog function: Bacterial conserved protein of unknown function (DUF910) family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1516 -42 4.5 TAGAAAGCGATTCCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0586 -60 4.2 CAGAAAGCGATTGCAT
Streptococcus mutans UA159 SMU.541 -58 3.9 AGGCAAGCGCTTGCAA
Streptococcus pyogenes M1 GAS SPy1530 -60 4.5 TAGAAAGCGATTCCAT
Streptococcus thermophilus CNRZ1066 str0727 -58 4 CTATAAAGGTTTTCAA
Position: -66
Score: 4.5
Sequence: TTGAAAACGTTTTACA
Locus tag: SMU.575c
SMU.575c -66 4.5 TTGAAAACGTTTTACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lrgA
Ortholog function: Antiholin-like protein LrgA
Streptococcus agalactiae 2603V/R SAG0184 -87 4.9 ATGAAAACGTTTTATT
Streptococcus agalactiae 2603V/R SAG1147 -66 4.3 ATGTAAACGTTTCATA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0332 -55 4.8 TAGAAAGCGTTTTATT
Streptococcus gallolyticus UCN34 GALLO_0983 -68 4.2 ATGTAAACGTTTCAAG
Streptococcus mitis B6 smi_0576 -109 4.1 TTGTATGCCCTTTCTA
Streptococcus mutans UA159 SMU.575c -66 4.5 TTGAAAACGTTTTACA
Streptococcus sanguinis SK36 SSA_0842 -83 4.4 ATGTAAAGGTTTTAAT
Streptococcus suis 05ZYH33 SSU05_0265 -132 4.1 GTGTAAACGTTTTATA
Position: -127
Score: 3.9
Sequence: TTGAAAACGATCATTT
Locus tag: SMU.611
SMU.611 -127 3.9 TTGAAAACGATCATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: rheA
Ortholog function: Cold-shock DEAD-box protein A
Streptococcus agalactiae 2603V/R SAG0777 -142 4.2 ATGAAAGCGTGTTATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1455 -146 4.2 ATGAAAACGTGTTATT
-53 4 ATTAAAAGGTTTATAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0646 -135 4.5 ATAAAAACACTTTCAT
-53 4 ATTAAAAGGTTTATAA
Streptococcus gallolyticus UCN34 GALLO_0655 -139 4.2 ATGAAAACGTGTTATT
-116 3.9 ATGAAACTGTTTCCTA
Streptococcus mutans UA159 SMU.611 -127 3.9 TTGAAAACGATCATTT
Streptococcus pyogenes M1 GAS SPy1415 -199 3.7 CAAAAAACGATATCTT
-53 4 ATTAAAAGGTTTATAA
Streptococcus suis 05ZYH33 SSU05_1574 -166 4.4 ATGAAAACGTATTATT
Streptococcus uberis 0140J SUB1250 -70 4.5 ATAAAAACCTTTTCAT
Position: -60
Score: 4.3
Sequence: TTGTAAGGGTTATCAT
Locus tag: SMU.674
SMU.674 -60 4.3 TTGTAAGGGTTATCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ptsH
Ortholog function: Phosphotransferase system, HPr-related protein
Streptococcus agalactiae 2603V/R SAG0821 -60 3.8 TTGTAAGGGTTACCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1421 -167 4 AAGAAAACGAATAAAA
-58 4.3 TTGTAAGGGTTATCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0764 -136 4.2 AAGAAAACTGTTTCAT
-58 4.3 TTGTAAGGGTTATCAT
Streptococcus gallolyticus UCN34 GALLO_0744 -200 4.4 ATGAAAACGCTCAAAA
-122 3.8 AAGAAAGCGCGCACAA
-58 4.3 TTGTAAGGGTTATCAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1556 -90 4.4 TTGAAAAAGATTTCAA
-55 4.3 TTGTAAGGGTTATCAA
Streptococcus mitis B6 smi_1045 -196 4.2 TATAAATCGTTTTTAA
Streptococcus mutans UA159 SMU.674 -60 4.3 TTGTAAGGGTTATCAT
Streptococcus pyogenes M1 GAS SPy1373 -58 4.3 TTGTAAGGGTTATCAT
Streptococcus sanguinis SK36 SSA_0772 -90 4.4 TTGAAAAAGATTTCAA
Streptococcus suis 05ZYH33 SSU05_1201 -91 4.5 TTGAAAATGATTTCAA
Streptococcus thermophilus CNRZ1066 str1265 -56 4.3 TTGTAAGGGTTATCAT
Streptococcus uberis 0140J SUB1223 -137 3.8 AAGAAAACATTTCAAA
-60 3.9 TTGTAAGGGTTACCAT
Position: -109
Score: 4.3
Sequence: TAGGAAACGCTTCCAA
Locus tag: SMU.799c
SMU.799c -109 4.3 TAGGAAACGCTTCCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: SPy1339
Ortholog function: Dihydrolipoamide acyltransferase
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1320 -54 4.2 CTGAAAGCGCTTAATG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1291 -44 3.8 CTGTAAGCCCTTAATA
Streptococcus mutans UA159 SMU.799c -109 4.3 TAGGAAACGCTTCCAA
Streptococcus pyogenes M1 GAS SPy1339 -53 4.3 CTGTAAGCGCTTAATA
Position: 22
Score: 4.4
Sequence: GTGTAAACGATTTCAA
Locus tag: SMU.870
SMU.870 22 4.4 GTGTAAACGATTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruR
Ortholog function: Fructose utilization transcriptional regulator FruR, DeoR family
Lactococcus lactis subsp. cremoris SK11 LACR_1031 -25 4.2 TTGTAAACGAATTCAG
Lactococcus lactis subsp. lactis Il1403 L0031 -25 4.2 TTGTAAACGAATTCAG
Streptococcus agalactiae 2603V/R SAG1348 -30 4.7 TTGCAAACGATTTCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0811 -60 4.1 CTGTAACCGATTTCAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1106 -62 4.4 CTGTAAACGATTTCAG
Streptococcus gallolyticus UCN34 GALLO_1319 -30 4.4 CTGTAAACGATTTCAG
Streptococcus gordonii str. Challis substr. CH1 SGO_1111 -27 4 ATGTAAGCTGTTTCAG
Streptococcus mutans UA159 SMU.870 22 4.4 GTGTAAACGATTTCAA
Streptococcus pyogenes M1 GAS SPy0853 -60 4.7 TTGTAAACGATTTCAG
Streptococcus suis 05ZYH33 SSU05_0822 14 4.2 TTGTAAACGGTTGCAG
Streptococcus thermophilus CNRZ1066 str0399 -109 3.8 AGGTTAGCGTTTTATA
-27 4.5 TTGTAAACGATTACAG
Streptococcus uberis 0140J SUB0748 -60 4.4 TTGTAACCGATTTCAG
Position: -73
Score: 4.6
Sequence: TTGTAACCGTTTTAAA
Locus tag: SMU.876
SMU.876 -73 4.6 TTGTAACCGTTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: msmR
Ortholog function: Predicted multiple sugar utilization transcriptional regulator, AraC family
Streptococcus mutans UA159 SMU.876 -73 4.6 TTGTAACCGTTTTAAA
Position: -50
Score: 4.6
Sequence: TTTAAAACGGTTACAA
Locus tag: SMU.877
SMU.877 -50 4.6 TTTAAAACGGTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: agaL
Ortholog function: Alpha-galactosidase (EC 3.2.1.22)
Streptococcus mutans UA159 SMU.877 -50 4.6 TTTAAAACGGTTACAA
Streptococcus pneumoniae TIGR4 SP_1898 -55 4.3 TGGAAAGCGATTTCAG
Streptococcus sanguinis SK36 SSA_1002 -50 4.5 TAGGAAGCGATTTCAT
Streptococcus suis 05ZYH33 SSU05_1560 -52 5 AATAAAGCGTTTTCAT
Position: -115
Score: 5
Sequence: TTTTAAGCGCTTTCAT
Locus tag: SMU.1013c
SMU.1013c -115 5 TTTTAAGCGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: citN
Ortholog function: Mg2+/citrate complex secondary transporter
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0992 -56 4.6 TTCTAAGCGCTTTCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0988 -54 4.4 TTGCGAACGCTTTCAT
Streptococcus mutans UA159 SMU.1013c -160 3.9 TTTAAAATGTTTTTTT
-115 5 TTTTAAGCGCTTTCAT
Streptococcus pyogenes M1 GAS SPy1180 -122 4 TAAAAATGGTTTTCAA
-52 4.9 TTATAAGCGCTTTCAT
Position: -55
Score: 4.7
Sequence: ATGAAAGCGGTTAAAT
Locus tag: SMU.1077
SMU.1077 -55 4.7 ATGAAAGCGGTTAAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pgm
Ortholog function: Phosphoglucomutase (EC 5.4.2.2)
Streptococcus agalactiae 2603V/R SAG1066 -35 4.9 ATGAAAGCGTTTATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1043 -34 4.7 ATGAAAGCGGTTAAAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0941 0 4.7 ATGAAAGCGGTTAAAA
Streptococcus gallolyticus UCN34 GALLO_1123 -39 4.6 ATGAAAGCGTTTAGAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1215 -83 4.4 ATGAAAGCGATTAGAT
Streptococcus mitis B6 smi_1173 -40 4.5 ATGTAAACGATTAAAA
Streptococcus mutans UA159 SMU.1077 -55 4.7 ATGAAAGCGGTTAAAT
Streptococcus pyogenes M1 GAS SPy1224 -35 4.9 ATGAAAGCGTTTATAA
Streptococcus sanguinis SK36 SSA_1204 -137 4 ATTTCATCGTTTTCTA
Streptococcus suis 05ZYH33 SSU05_0686 -40 4.8 ATGAAAGCGTTTAATA
Streptococcus thermophilus CNRZ1066 str0787 -33 4.8 ATGTAAGCGTTTAAAA
Streptococcus uberis 0140J SUB0946 -34 4.5 ATGAAAGCGGTTAATA
Position: -50
Score: 4.6
Sequence: CAGAAAACGCTATCAT
Locus tag: SMU.1088
SMU.1088 -50 4.6 CAGAAAACGCTATCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: apbE
Ortholog function: Predicted thiamine biosynthesis lipoprotein
Streptococcus agalactiae 2603V/R SAG1081 -45 4.5 TAGAAAACGGTATCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0897 -86 4.1 TGGTAAGCCTTTTCAA
Streptococcus gallolyticus UCN34 GALLO_1031 -122 3.8 TTTAAAACACTTACTG
-47 4.3 TAGAAAGCGTTATCCT
Streptococcus gordonii str. Challis substr. CH1 SGO_1168 -100 4.1 GTGAAAACGTTGTCTT
31 4 ATGAAAATGCTGACTT
Streptococcus mitis B6 smi_1391 -116 4 GTGAAAACGCTGACTT
Streptococcus mutans UA159 SMU.1088 -50 4.6 CAGAAAACGCTATCAT
Streptococcus pneumoniae TIGR4 SP_1470 -72 4 ATGTAAGGGCTTCAAT
Streptococcus uberis 0140J SUB0868 -75 4.4 ATAATAGCGGTTTCAA
Position: -52
Score: 4.5
Sequence: TTGAAACGGTTTTCAA
Locus tag: SMU.1126
SMU.1126 -52 4.5 TTGAAACGGTTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: coaA
Ortholog function: Pantothenate kinase (EC 2.7.1.33)
Lactococcus lactis subsp. cremoris SK11 LACR_1533 -68 4.1 TTTAATACGCTTACAG
Lactococcus lactis subsp. lactis Il1403 L66222 -68 4.1 TTTAATACGCTTACAG
Streptococcus agalactiae 2603V/R SAG0951 -60 4.5 TTGAAACGGTTTTCAA
-29 3.9 TTATAATAGCTTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1052 -199 3.9 TTTTAAAGGTTTCCAA
-32 4.2 ATGTAAGCACTGTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0931 -223 4.4 TTGAAATGGTTTACAA
Streptococcus gallolyticus UCN34 GALLO_1139 -69 4.4 TTGTAACGGTTTTCAA
-47 3.8 ATTAAAGTGCTATAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1077 -74 4.1 TGTAAATCGTTTACAT
Streptococcus mitis B6 smi_0883 -64 4.5 AAGAAACCGCTTTATT
Streptococcus mutans UA159 SMU.1126 -52 4.5 TTGAAACGGTTTTCAA
Streptococcus pneumoniae TIGR4 SP_0839 -64 4.5 AAGAAACCGCTTTATT
Streptococcus pyogenes M1 GAS SPy1233 -223 4.4 TTGAAATGGTTTACAA
-32 4.2 ATGTAAGCACTGTCAA
Streptococcus sanguinis SK36 SSA_1033 -64 4.3 TGTAAATCGTTTTCAT
Streptococcus suis 05ZYH33 SSU05_1088 -89 4.7 CTAAAAACGTTTTCAA
-32 4 ATTGAAACGCTTACCT
Streptococcus thermophilus CNRZ1066 str0799 -45 4.3 TTGATAAGGCTTACAT
Streptococcus uberis 0140J SUB0955 -219 4.4 TTGAAATGGTTTACAA
Position: 8
Score: 4.2
Sequence: TTTTAATCGTATTCAT
Locus tag: SMU.1233
SMU.1233 8 4.2 TTTTAATCGTATTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: deoB
Ortholog function: Phosphopentomutase (EC 5.4.2.7)
Streptococcus agalactiae 2603V/R SAG1182 -110 4.6 AAGAAAATGTTTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1164 -61 4.3 AAGTTTGCGCTTTCAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1264 -120 4.3 AGGAAAATGCTTTCAT
Streptococcus pneumoniae TIGR4 SP_0829 -53 4.4 ATAAAAGCCTTTACAT
Streptococcus pyogenes M1 GAS SPy0890 -171 4 AAGTAAGTGCTTATAT
Streptococcus sanguinis SK36 SSA_1260 -66 4.7 AAGAAAACACTTTCAT
Streptococcus thermophilus CNRZ1066 str1120 -94 4.5 TTGATAGCCTTTTCAT
Position: -65
Score: 4.4
Sequence: ATAACAGCGTTTACAT
Locus tag: SMU.1389
SMU.1389 -65 4.4 ATAACAGCGTTTACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pck
Ortholog function: Phosphoenolpyruvate carboxykinase (EC 4.1.1.49)
Streptococcus gallolyticus UCN34 GALLO_0747 -57 4.5 ATGAAAGCGTATGCAA
Streptococcus mutans UA159 SMU.1389 -65 4.4 ATAACAGCGTTTACAT
Streptococcus uberis 0140J SUB1583 -56 4.2 TGGTAAGCGTTTTCCT
Position: -302
Score: 3.8
Sequence: TTTTAAACGTTTTTTC
Position: -189
Score: 4.1
Sequence: ATAGAAACGCTTACAG
Locus tag: SMU.1405c
SMU.1405c -302 3.8 TTTTAAACGTTTTTTC
-189 4.1 ATAGAAACGCTTACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cas9
Ortholog function: CRISPR/Cas system-associated protein Cas9
Streptococcus agalactiae 2603V/R SAG0894 -99 3.9 AAGATAATGCTTTTAA
Streptococcus mutans UA159 SMU.1405c -189 4.1 ATAGAAACGCTTACAG
Position: -58
Score: 5.2
Sequence: TAGAAAGCGTTTTCAA
Locus tag: SMU.1424
SMU.1424 -58 5.2 TAGAAAGCGTTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pdhD
Ortholog function: Dihydrolipoamide dehydrogenase of acetoin dehydrogenase (EC 1.8.1.4)
Streptococcus mutans UA159 SMU.1424 -95 4.2 TTGAAATCCCTATCAA
-58 5.2 TAGAAAGCGTTTTCAA
Streptococcus sanguinis SK36 SSA_1137 -195 4.8 AAGTAAGCGCTTACTA
Position: 19
Score: 4.1
Sequence: AAATTAGCGCTTTAAT
Locus tag: SMU.1530
SMU.1530 19 4.1 AAATTAGCGCTTTAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: atpA
Ortholog function: ATP synthase alpha chain (EC 3.6.3.14)
Lactococcus lactis subsp. cremoris SK11 LACR_1935 -135 4.3 TATCAAACGCTTACAA
Streptococcus agalactiae 2603V/R SAG0861 -93 4.5 ATGAAAACGTAATCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1544 -96 4.6 TTAAAATCGCTTACAA
Streptococcus mitis B6 smi_1311 -93 4.5 CATTAAACGCTTTCAA
Streptococcus mutans UA159 SMU.1530 -161 4.1 TTAAAAGCGTCTTCTA
Streptococcus pneumoniae TIGR4 SP_1510 -93 4.3 TATTAAACGCTTCCAA
Streptococcus sanguinis SK36 SSA_0786 -194 4.5 TTTTAATCGCTTTCTT
-95 4.4 CAAAAAACGCTTACAA
Streptococcus suis 05ZYH33 SSU05_1174 -92 4.7 AATTAAACGCTTACAA
Streptococcus uberis 0140J SUB0670 -94 4.4 AAGAAAGCGTAATCAA
Position: -161
Score: 4.1
Sequence: TTAAAAGCGTCTTCTA
Locus tag: SMU.1534
SMU.1534 -161 4.1 TTAAAAGCGTCTTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: atpE
Ortholog function: ATP synthase C chain (EC 3.6.3.14)
Lactococcus lactis subsp. cremoris SK11 LACR_1939 -135 4.3 TATCAAACGCTTACAA
Lactococcus lactis subsp. lactis Il1403 L11729a -135 4.2 CTTCAAACGCTTACAA
Streptococcus agalactiae 2603V/R SAG0857 -93 4.5 ATGAAAACGTAATCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1548 -96 4.6 TTAAAATCGCTTACAA
Streptococcus mitis B6 smi_1315 -93 4.5 CATTAAACGCTTTCAA
Streptococcus mutans UA159 SMU.1534 -161 4.1 TTAAAAGCGTCTTCTA
Streptococcus sanguinis SK36 SSA_0782 -194 4.5 TTTTAATCGCTTTCTT
-95 4.4 CAAAAAACGCTTACAA
Streptococcus suis 05ZYH33 SSU05_1178 -92 4.7 AATTAAACGCTTACAA
Streptococcus uberis 0140J SUB0666 -94 4.4 AAGAAAGCGTAATCAA
Position: -189
Score: 3.8
Sequence: TTGTTAACCTTTTATA
Locus tag: SMU.1568
SMU.1568 -189 3.8 TTGTTAACCTTTTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: malE
Ortholog function: Maltose/maltodextrin ABC transporter, substrate-binding protein
Lactococcus lactis subsp. cremoris SK11 LACR_1853 -163 4.1 TTTAAAGGGCTTTATT
-32 4.7 AATAAACCGTTTTCAT
Lactococcus lactis subsp. lactis Il1403 L128695 -32 4.7 AATAAACCGTTTTCAT
Streptococcus agalactiae 2603V/R SAG1441 -58 4.2 TTGCAAACGGTTGCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1296 -56 3.9 CTGCAAGCGGTTGCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1257 -56 3.9 CTGCAAGCGGTTGCAT
Streptococcus gallolyticus UCN34 GALLO_1399 -156 4.7 ATGAAATCGCTTAAAT
-66 3.9 CTGCAAACGGTTGCAT
Streptococcus mutans UA159 SMU.1568 -189 3.8 TTGTTAACCTTTTATA
Streptococcus pyogenes M1 GAS SPy1294 -56 3.9 CTGCAAGCGGTTGCAT
Streptococcus sanguinis SK36 SSA_1298 -200 4.8 AATAAAGCGCTTTCTA
-54 4.2 TTGCAAACGGTTGCAT
Streptococcus uberis 0140J SUB1143 -53 3.9 CTGCAAACGGTTGCAT
Position: -72
Score: 4.8
Sequence: TTGAAAGTGTTTTCAA
Locus tag: SMU.1591
SMU.1591 -72 4.8 TTGAAAGTGTTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ccpA
Ortholog function: Carbon catabolism global transcriptional regulator CcpA, LacI family
Lactococcus lactis subsp. cremoris SK11 LACR_1812 -93 4.4 TTGAAAAGGTTTACAG
Lactococcus lactis subsp. lactis Il1403 L0143 -93 4.4 TTGAAAAGGTTTACAG
-57 4.1 TAAAAATGGTTTTCAT
Streptococcus agalactiae 2603V/R SAG0707 -74 4.3 TTGAAAGTGTTTCCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0545 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1410 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus gallolyticus UCN34 GALLO_1582 -122 4.7 AATTAAACGCTTACAA
-71 4.3 TTGAAAGTGTTTCCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0773 -82 4.3 TTGAAAGTGTTTCCAA
-38 4.5 ATGAAAACGTTATTTT
Streptococcus mitis B6 smi_0284 -113 4.6 TTGAAAGTGTTTACAA
Streptococcus mutans UA159 SMU.1591 -72 4.8 TTGAAAGTGTTTTCAA
Streptococcus pneumoniae TIGR4 SP_1999 -150 4.6 TTGAAAGTGTTTACAA
Streptococcus pyogenes M1 GAS SPy0514 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus sanguinis SK36 SSA_1576 -81 4.6 TTGAAAGTGTTTACAA
Streptococcus thermophilus CNRZ1066 str0630 -41 4.8 TTGAAAGTGTTTTCAA
Streptococcus uberis 0140J SUB0536 -72 4.5 TTGAAAGTGGTTTCAA
Position: -106
Score: 4.8
Sequence: TTGAAAACACTTTCAA
Locus tag: SMU.1592
SMU.1592 -106 4.8 TTGAAAACACTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pepQ
Ortholog function: Xaa-Pro dipeptidase (EC 3.4.13.9)
Lactococcus lactis subsp. cremoris SK11 LACR_1813 -136 4.4 CTGTAAACCTTTTCAA
Lactococcus lactis subsp. lactis Il1403 L96847 -173 4.1 ATGAAAACCATTTTTA
-137 4.4 CTGTAAACCTTTTCAA
Streptococcus agalactiae 2603V/R SAG0706 -151 4.3 TTGGAAACACTTTCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0544 -151 4 AAAATTACGCTTTCAA
-117 4.3 TTGTAACCACTTTCAA
-84 4.6 TTGAAAAAGTTTTCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0771 -142 4.5 AAAATAACGTTTTCAT
-98 4.3 TTGGAAACACTTTCAA
Streptococcus mutans UA159 SMU.1592 -106 4.8 TTGAAAACACTTTCAA
Streptococcus pyogenes M1 GAS SPy0513 -117 4.3 TTGTAACCACTTTCAA
-84 4.6 TTGAAAAAGTTTTCAA
Streptococcus sanguinis SK36 SSA_1577 -97 4.6 TTGTAAACACTTTCAA
Streptococcus suis 05ZYH33 SSU05_1373 -135 4.5 TTGAAACCACTTTCAA
Streptococcus thermophilus CNRZ1066 str0629 -134 3.8 TATTCATCGCTTACAA
Streptococcus uberis 0140J SUB0535 -115 4.5 TTGAAACCACTTTCAA
Position: -55
Score: 4.8
Sequence: TTGTAAGCGCTTTTTT
Locus tag: SMU.1600
SMU.1600 -55 4.8 TTGTAAGCGCTTTTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: celB
Ortholog function: Cellobiose-specific PTS, component EIIB
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1401 -48 4.5 TTGTAAAGGTTTTCTA
Streptococcus gallolyticus UCN34 GALLO_1213 -56 4.9 ATGTAAGCGTTTTTAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1580 -61 4.3 TTGATGGCGTTTTCAT
Streptococcus mutans UA159 SMU.1600 -55 4.8 TTGTAAGCGCTTTTTT
Streptococcus pneumoniae TIGR4 SP_0305 -90 4.5 TTGGAAACGCTTTATT
Streptococcus uberis 0140J SUB0529 -65 4.2 TTGAAAGCGTATACAC
Position: -46
Score: 3.9
Sequence: TTGAAATTGTTTGCTA
Locus tag: SMU.1601
SMU.1601 -46 3.9 TTGAAATTGTTTGCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: bglA
Ortholog function: 6-phospho-beta-glucosidase (EC 3.2.1.86)
Streptococcus gallolyticus UCN34 GALLO_1217 -49 4.3 TTGTAACCGCTTGCTA
Streptococcus gordonii str. Challis substr. CH1 SGO_1582 -145 4.9 TTGAAAGCGTTGTCAA
-57 4.2 AAAACAGCGCTTTCTT
Streptococcus mutans UA159 SMU.1601 -46 3.9 TTGAAATTGTTTGCTA
Streptococcus pneumoniae TIGR4 SP_0303 -66 4.8 AAGAATGCGTTTTCAT
Position: -28
Score: 4
Sequence: AGAAAAACGTTTACAG
Locus tag: SMU.1692
SMU.1692 -28 4 AGAAAAACGTTTACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: pflA
Ortholog function: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4)
Streptococcus agalactiae 2603V/R SAG1398 -47 3.8 ATGAAAATGATATAAT
-25 4.6 ATAAAAACGGTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1625 -32 4 GTAAAACCGTTTACAA
Streptococcus gallolyticus UCN34 GALLO_1781 -51 3.9 TAGAAAATGTTATAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1649 -33 4.6 TATAAAACGTTTTCAG
Streptococcus mitis B6 smi_0304 -29 4.9 TATAAAACGTTTTCAA
Streptococcus mutans UA159 SMU.1692 -28 4 AGAAAAACGTTTACAG
Streptococcus pneumoniae TIGR4 SP_1976 -29 4.9 TATAAAACGTTTTCAA
Streptococcus pyogenes M1 GAS SPy0379 -33 4.3 GTAAAAACGTTTACAA
Streptococcus sanguinis SK36 SSA_1749 -33 4.6 TATAAAACGTTTTCAG
Streptococcus suis 05ZYH33 SSU05_1667 -55 4.6 ATAGAAGCGTTTTCAT
Streptococcus uberis 0140J SUB0417 -33 4 GTAAAAACGGTTACAA
Position: -154
Score: 4.9
Sequence: TAGTAAACGTTTTCTT
Position: -47
Score: 4.9
Sequence: AAAAAAACGCTTTCAA
Locus tag: SMU.1841
SMU.1841 -154 4.9 TAGTAAACGTTTTCTT
-47 4.9 AAAAAAACGCTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: scrA
Ortholog function: Sucrose-specific PTS system, IIABC component (EC 2.7.1.69)
Streptococcus gallolyticus UCN34 GALLO_1892 -162 4.9 TAGTAAACGTTTTCTT
Streptococcus mutans UA159 SMU.1841 -154 4.9 TAGTAAACGTTTTCTT
-47 4.9 AAAAAAACGCTTTCAA
Position: -164
Score: 4.9
Sequence: TTGAAAGCGTTTTTTT
Position: -57
Score: 4.9
Sequence: AAGAAAACGTTTACTA
Locus tag: SMU.1843
SMU.1843 -164 4.9 TTGAAAGCGTTTTTTT
-57 4.9 AAGAAAACGTTTACTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: scrB
Ortholog function: Sucrose-6-phosphate hydrolase (EC 3.2.1.26)
Streptococcus agalactiae 2603V/R SAG1691 -163 4.5 TTGAAAGCGTTTCATT
-54 4.3 GAGAAAACGTTTACTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1872 -53 4.2 AAGAAAACGTTTAGTA
Streptococcus gallolyticus UCN34 GALLO_1893 -52 4.9 AAGAAAACGTTTACTA
Streptococcus gordonii str. Challis substr. CH1 SGO_1858 -163 4.8 TTGAAAGCGATTTTAT
-53 4.6 CAGAAAACGTTTACTA
Streptococcus mitis B6 smi_1616 -176 4 TTAAAAGGGTTTTATT
Streptococcus mutans UA159 SMU.1843 -164 4.9 TTGAAAGCGTTTTTTT
-57 4.9 AAGAAAACGTTTACTA
Streptococcus sanguinis SK36 SSA_0455 -161 4.8 TTGAAAGCGATTTTAT
-53 4.6 CAGAAAACGTTTACTA
Streptococcus suis 05ZYH33 SSU05_1818 -52 4.8 TTGAAAGTGTTTTCAA
Streptococcus thermophilus CNRZ1066 str1735 -158 4 TTGAAAACGTTTCACT
Position: -105
Score: 4.4
Sequence: ATGTAAACGTTTTACA
Locus tag: SMU.1877
SMU.1877 -105 4.4 ATGTAAACGTTTTACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: manL
Ortholog function: PTS system, mannose-specific IIAB components
Lactococcus lactis subsp. cremoris SK11 LACR_1863 -87 4.3 ATGAAAACATTTGCAA
Lactococcus lactis subsp. lactis Il1403 L1762179 -87 4.3 ATGAAAACATTTGCAA
Streptococcus agalactiae 2603V/R SAG0361 -130 4.7 CTGAAAACGTTTTAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1806 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0423 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus gallolyticus UCN34 GALLO_0350 -128 4.5 TTGAAAACGTTTTACA
Streptococcus gordonii str. Challis substr. CH1 SGO_1679 -80 4.6 CTGAAAACGTTTTATA
Streptococcus mitis B6 smi_0274 -124 4.2 ATTTAAATGTTTTCTT
-77 4.6 ATGAAAACGGTTTATA
Streptococcus mutans UA159 SMU.1877 -105 4.4 ATGTAAACGTTTTACA
Streptococcus pneumoniae TIGR4 SP_0284 -68 4.6 ATGAAAACGGTTTATA
Streptococcus pyogenes M1 GAS SPy1738 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus sanguinis SK36 SSA_1918 -71 4.9 ATGAAAACGTTTTATA
Streptococcus suis 05ZYH33 SSU05_1778 -91 4.2 CTGTAATCGTTTTATA
-59 4.4 ATGAAAGCCCATTCAA
Streptococcus thermophilus CNRZ1066 str0333 -139 4.5 ATGATAACGCTTTATA
Streptococcus uberis 0140J SUB1482 -130 5 TTGAAAACGTTTTAAA
Position: -28
Score: 4.3
Sequence: TCGTAAACGATTTCAT
Locus tag: SMU.1978
SMU.1978 -28 4.3 TCGTAAACGATTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ackA
Ortholog function: Acetate kinase (EC 2.7.2.1)
Lactococcus lactis subsp. cremoris SK11 LACR_2294 -30 4.3 AATAAAACGCATACAT
Lactococcus lactis subsp. cremoris SK11 LACR_2295 -129 4.4 ATGCAAACGCTTTTTA
Lactococcus lactis subsp. lactis Il1403 L0224 -30 4.3 AATAAAACGCATACAT
Lactococcus lactis subsp. lactis Il1403 L73818 -129 4.5 TTGAAAAGGTTTTTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0142 -28 4.9 TAGAAAACGATTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0124 -28 4.6 CAGAAAACGATTTCAA
Streptococcus gallolyticus UCN34 GALLO_0095 -25 4.4 ATGAAAGCGCTTTAGA
Streptococcus gordonii str. Challis substr. CH1 SGO_1916 -26 4.6 CTGAAAACGCTTAAAA
Streptococcus mitis B6 smi_0214 -90 5 ATGAAAACGCTTAAAA
Streptococcus mutans UA159 SMU.1978 -28 4.3 TCGTAAACGATTTCAT
Streptococcus pneumoniae TIGR4 SP_2044 -30 4.9 TTGAAAACGCTTAAAA
Streptococcus pyogenes M1 GAS SPy0109 -28 4.6 CAGAAAACGATTTCAA
Streptococcus sanguinis SK36 SSA_0192 -26 4.6 TTGAAAACGCTTAAAG
3 4.3 TCGAAAACGATTTCTA
Streptococcus suis 05ZYH33 SSU05_0135 -27 4.5 AGGAAAACGCTTTAAA
Streptococcus thermophilus CNRZ1066 str1857 0 4.9 TTGAAAGCGTTTTATA
Streptococcus uberis 0140J SUB0126 -28 4.6 CAGAAAACGATTTCAA
Position: -77
Score: 4.8
Sequence: TTGTAATCGTTTACAA
Locus tag: SMU.2038
SMU.2038 -77 4.8 TTGTAATCGTTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: treP
Ortholog function: Trehalose-specific PTS system, IIABC components (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R SAG0192 -93 4.9 ATGTAATCGTTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2069 -111 4.3 TTGCAATCGATTACAA
Streptococcus gallolyticus UCN34 GALLO_2175 -82 4.4 TGGAAAACGATTACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1653 -89 4.1 TTGGTATCGTTTACAA
Streptococcus mutans UA159 SMU.2038 -77 4.8 TTGTAATCGTTTACAA
Streptococcus pneumoniae TIGR4 SP_1884 -63 4.1 TTGGTATCGTTTACAA
Streptococcus pyogenes M1 GAS SPy2097 -111 4.3 TTGCAATCGATTACAA
Streptococcus sanguinis SK36 SSA_1752 -30 4.3 TTGGAATCGATTACAA
Streptococcus suis 05ZYH33 SSU05_0231 -128 4.2 TTGAAATCGGATACAA
Streptococcus uberis 0140J SUB1763 -118 4.3 TTGGAATCGATTACAA
Position: -112
Score: 4.8
Sequence: TTGTAAACGATTACAA
Locus tag: SMU.2040
SMU.2040 -112 4.8 TTGTAAACGATTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: treR
Ortholog function: Trehalose utilization transcriptional regulator TreR, GntR family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2070 -115 4.3 TTGTAATCGATTGCAA
Streptococcus gallolyticus UCN34 GALLO_2176 -129 4.4 TTGTAATCGTTTTCCA
Streptococcus gordonii str. Challis substr. CH1 SGO_1654 -106 4.1 TTGTAAACGATACCAA
Streptococcus mutans UA159 SMU.2040 -112 4.8 TTGTAAACGATTACAA
Streptococcus pneumoniae TIGR4 SP_1885 -137 4.1 TTGTAAACGATACCAA
Streptococcus pyogenes M1 GAS SPy2099 -115 4.3 TTGTAATCGATTGCAA
Streptococcus sanguinis SK36 SSA_1753 -104 4.3 TTGTAATCGATTCCAA
Streptococcus suis 05ZYH33 SSU05_0232 -118 4.2 TTGTATCCGATTTCAA
Streptococcus uberis 0140J SUB1764 -117 4.3 TTGTAATCGATTCCAA
Position: -43
Score: 4.5
Sequence: ATGCAAACGTTTGCAT
Locus tag: SMU.2047
SMU.2047 -43 4.5 ATGCAAACGTTTGCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ptsG
Ortholog function: PTS system glucose-specific EIICBA component (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R SAG1959 -92 4.4 AAGTAAGGGTTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0222 -154 4.4 AAGAAAACGCTTTACA
-49 4.1 ATGATAGCGATTACCT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1783 -158 4.4 AAGAAAACGCTTTACA
Streptococcus gordonii str. Challis substr. CH1 SGO_0505 -96 4 ATGAAAACCCTTTACA
-47 4.7 ATGCAAACGATTTCAT
Streptococcus mitis B6 smi_1404 -103 4.4 ATAAAAGCCTTTACAA
Streptococcus mutans UA159 SMU.2047 -43 4.5 ATGCAAACGTTTGCAT
Streptococcus pneumoniae TIGR4 SP_0758 -102 4.4 ATAAAAGCCTTTACAA
Streptococcus pyogenes M1 GAS SPy1986 -155 4.4 AAGAAAACGCTTTACA
-101 4.3 ATGCAAGCGATTGCAT
Streptococcus sanguinis SK36 SSA_1809 -193 4 ATGCAATCGTTTTCGT
-103 4.4 ATAAAAGCCTTTACAA
-54 4.1 ATGCAAACGATTTCAC
Streptococcus thermophilus CNRZ1066 str0189 -72 4.4 AAGAAAACGCTTTACA
-21 3.9 ATGCAAACGCTCGCAT
Streptococcus thermophilus CNRZ1066 str0190 -72 4.4 AAGAAAACGCTTTACA
-21 3.9 ATGCAAACGCTCGCAT
Streptococcus thermophilus CNRZ1066 str0191 -72 4.4 AAGAAAACGCTTTACA
-21 3.9 ATGCAAACGCTCGCAT
Streptococcus uberis 0140J SUB0236 -120 4.3 TAGAAAACGCTTTACA
Position: -57
Score: 4.8
Sequence: TTGAAATCGGTTTCAA
Locus tag: SMU.2127
SMU.2127 -57 4.8 TTGAAATCGGTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gabD
Ortholog function: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)
Streptococcus agalactiae 2603V/R SAG1124 -53 4.8 TTGTAATCGATTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1202 -56 4.9 TTGAAATCGATTTCAA
Streptococcus gallolyticus UCN34 GALLO_0925 -146 4.1 ACGATAGCGTTTACTT
-132 4.1 TTGAAACCGTTTCCTG
Streptococcus mutans UA159 SMU.2127 -57 4.8 TTGAAATCGGTTTCAA
Streptococcus pyogenes M1 GAS SPy1067 -59 4.9 TTGAAATCGATTTCAT
Streptococcus uberis 0140J SUB1058 -56 4.3 TTGAAATCGTTACCAA
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