Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of HomR regulog to Streptococcus mutans UA159

Reference regulog properties
Source regulog: HomR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: activator
Biological process: Methionine metabolism; Cysteine metabolism
Effector: O-acetyl-L-serine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus mutans UA159
Orthologous TF(s) SMU.930c
Regulated genes 5
Built upon 24 sites [see more]
Predicted regulatory interactions in Streptococcus mutans UA159
Locus tag Position Score Sequence
Position: -188
Score: 5.4
Sequence: GTTATAGATGAAAACTATAAC
Locus tag: SMU.873
SMU.873 -188 5.4 GTTATAGATGAAAACTATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. lactis Il1403 L0100 -99 4.3 CATATAGTTTAAAACTATAGG
Streptococcus gallolyticus UCN34 GALLO_1316 -172 5.2 GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_0310 -182 5.2 GTTATAGTTTTTGATTATACC
-99 4.6 GATATAGTTTTTGGCTATATC
Streptococcus mitis B6 smi_1600 -101 4.8 GATATAGTTTCAAACTATATC
Streptococcus mutans UA159 SMU.873 -188 5.4 GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4 SP_0585 -251 5 GTTATAGTCTTTTCTAATAAC
-218 5 CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36 SSA_0416 -182 5.3 GTCATAATTTCTACCTATAGC
-99 5.2 GTTATAGTTTTAGACTATATC
Streptococcus suis 05ZYH33 SSU05_1774 -237 4.7 TTCATAGATAAAATCTATACC
-101 4.8 GTTATAGTCAAAAGTTATACC
Streptococcus thermophilus CNRZ1066 str0785 -60 4.6 GATATAGTTTAAAACTATATA
Position: -175
Score: 6.1
Sequence: GCTATAAATTTTATTTATGAC
Locus tag: SMU.930c
SMU.930c -175 6.1 GCTATAAATTTTATTTATGAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: GALLO_1277
Ortholog function: Homocysteine biosynthesis transcriptional regulator HomR, LysR family
Streptococcus gallolyticus UCN34 GALLO_1277 -113 5.7 GTTATAAAAAAATCTTATCAC
Streptococcus mutans UA159 SMU.930c -175 6.1 GCTATAAATTTTATTTATGAC
-110 5.2 GCCATAAGAAAAAGTTATCAC
Position: -103
Score: 6.1
Sequence: GTCATAAATAAAATTTATAGC
Locus tag: SMU.932
SMU.932 -103 6.1 GTCATAAATAAAATTTATAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyD
Ortholog function: Predicted uroporphyrinogen-III decarboxylase
Streptococcus gallolyticus UCN34 GALLO_1275 -104 5.6 GCTATAAGCAAATCTTATGGC
Streptococcus mutans UA159 SMU.932 -168 5.2 GTGATAACTTTTTCTTATGGC
-103 6.1 GTCATAAATAAAATTTATAGC
Position: -110
Score: 4.9
Sequence: CTTATAGTTTCTTTTTATAGC
Locus tag: SMU.1675
SMU.1675 -110 4.9 CTTATAGTTTCTTTTTATAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Streptococcus gallolyticus UCN34 GALLO_1768 -142 5.9 GTTATAGTTTTTACTTATAGC
Streptococcus mutans UA159 SMU.1675 -110 4.9 CTTATAGTTTCTTTTTATAGC
Streptococcus thermophilus CNRZ1066 str0352 -132 5.4 GTTATAGTAATAAACTATATC
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