Propagation of CmbR regulog to Streptococcus mutans UA159

Reference regulog properties
Source regulog:	CmbR - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Cysteine metabolism
Effector:	O-acetyl-L-serine
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus mutans UA159
Orthologous TF(s)	SMU.1225, SMU.852
Regulated genes	10

Built upon 104 sites [see more]

Predicted regulatory interactions in *Streptococcus mutans UA159*
	Locus tag	Position	Score	Sequence
Position: -102 Score: 5.8 Sequence: GTGATAGAAAAATATTATCAC Position: -80 Score: 5 Sequence: GTGATAGGAAAAAACTATTAT Locus tag: SMU.459
	SMU.459	-102	5.8	GTGATAGAAAAATATTATCAC
		-80	5	GTGATAGGAAAAAACTATTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyA
Ortholog function: Cystine ABC transporter, substrate-binding protein
Lactococcus lactis subsp. cremoris SK11	LACR_1009	-77	5.1	GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403	L162009	-77	5.1	GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R	SAG0290	-96	5.5	TTGATATAAAATCTTTATCAC
		-75	4.7	CTGATAAGGAAATACTATTAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1582	-98	4.7	TTGATACTATTTTCTTATTGC
		-76	4.2	TTGATAGAGAAATGATATTAT
Streptococcus gallolyticus UCN34	GALLO_0414	-100	5.2	CTGATAGTTTTTTCTTATCAA
Streptococcus mutans UA159	SMU.459	-102	5.8	GTGATAGAAAAATATTATCAC
		-80	5	GTGATAGGAAAAAACTATTAT
Streptococcus uberis 0140J	SUB1416	-98	4.5	GTCATATAAATAGCTAATTAC
		-76	4.2	TTGATAGAAAAATGGTATTAT

Position: -77 Score: 5 Sequence: GTGATAAATAATTTATATTTT Locus tag: SMU.496
	SMU.496	-77	5	GTGATAAATAATTTATATTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Lactococcus lactis subsp. lactis Il1403	L0089	-79	5.3	GCTATAAAAAAATCTTATAGC
Lactococcus lactis subsp. lactis Il1403	L0088	-87	4.5	ATCATAAATTTTTTTTAGAGC
Streptococcus mitis B6	smi_2060	-98	5.3	GATATAAAAAAATCCTATCAC
Streptococcus thermophilus CNRZ1066	str0366	-16	5.2	ATGATAAAATTTTTTTATGGA
Streptococcus uberis 0140J	SUB1379	-104	5.1	ATGATAAGCCTTTCCTATCAC

Position: -188 Score: 4.6 Sequence: GTTATAGATGAAAACTATAAC Position: -100 Score: 4 Sequence: TTAATAAGGATTATCTAGTAT Locus tag: SMU.873
	SMU.873	-188	4.6	GTTATAGATGAAAACTATAAC
		-100	4	TTAATAAGGATTATCTAGTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. cremoris SK11	LACR_1368	-39	4.7	TTGATAAGATAGACCTATTAA
Lactococcus lactis subsp. lactis Il1403	L0100	-76	4.1	ATCATATTAAAAATGTATTAT
		-39	4.7	TTGATAAGATAGACCTATTAA
Streptococcus agalactiae 2603V/R	SAG2049	-109	4.1	GCTAAAAATATAAAATATTAA
Streptococcus gallolyticus UCN34	GALLO_1316	-221	4.2	ATAATAAATTTTATTAATCTA
		-172	4.6	GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0310	-182	4.2	GTTATAGTTTTTGATTATACC
Streptococcus mutans UA159	SMU.873	-188	4.6	GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4	SP_0585	-218	4.9	CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36	SSA_0416	-182	4.3	GTCATAATTTCTACCTATAGC
Streptococcus suis 05ZYH33	SSU05_1774	-237	4.3	TTCATAGATAAAATCTATACC
Streptococcus thermophilus CNRZ1066	str0785	-119	4.2	GCTATACAAATATCTAATTAA

Position: -175 Score: 5.3 Sequence: GCTATAAATTTTATTTATGAC Locus tag: SMU.930c
	SMU.930c	-175	5.3	GCTATAAATTTTATTTATGAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: homR
Ortholog function: Homocysteine biosynthesis transcriptional regulato HomR, LysR family
Streptococcus gallolyticus UCN34	GALLO_1277	-175	4.4	ATAATCTAAATTTTTTATTAT
		-113	5.9	GTTATAAAAAAATCTTATCAC
Streptococcus mutans UA159	SMU.930c	-175	5.3	GCTATAAATTTTATTTATGAC
		-110	5	GCCATAAGAAAAAGTTATCAC
Streptococcus thermophilus CNRZ1066	str0452	-108	5.3	TTTATAAAAATTTCATATCAG

Position: -168 Score: 5 Sequence: GTGATAACTTTTTCTTATGGC Position: -103 Score: 5.3 Sequence: GTCATAAATAAAATTTATAGC Locus tag: SMU.932
	SMU.932	-168	5	GTGATAACTTTTTCTTATGGC
		-103	5.3	GTCATAAATAAAATTTATAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyD
Ortholog function: Predicted uroporphyrinogen-III decarboxylase
Streptococcus gallolyticus UCN34	GALLO_1275	-104	4.9	GCTATAAGCAAATCTTATGGC
Streptococcus mutans UA159	SMU.932	-168	5	GTGATAACTTTTTCTTATGGC
		-103	5.3	GTCATAAATAAAATTTATAGC
Streptococcus sanguinis SK36	SSA_2105	-194	5.3	TTGATAAAAATTACCTATCTC
		-59	5.1	TTGATAAATATTTTTAATCAG
Streptococcus sanguinis SK36	SSA_2102	-194	5.3	TTGATAAAAATTACCTATCTC
		-59	5.1	TTGATAAATATTTTTAATCAG

Position: -110 Score: 4.3 Sequence: CTTATAGTTTCTTTTTATAGC Locus tag: SMU.1675
	SMU.1675	-110	4.3	CTTATAGTTTCTTTTTATAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB1
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Lactococcus lactis subsp. lactis Il1403	L0102	-132	4.3	GCCATAGGCAAGTTTTATTAT
Streptococcus gallolyticus UCN34	GALLO_1768	-142	5	GTTATAGTTTTTACTTATAGC
Streptococcus mutans UA159	SMU.1675	-110	4.3	CTTATAGTTTCTTTTTATAGC
Streptococcus suis 05ZYH33	SSU05_1562	-120	5.1	GTTATAAAGAAAAACTATAAC
Streptococcus thermophilus CNRZ1066	str0352	-132	4.5	GTTATAGTAATAAACTATATC

Position: -98 Score: 6 Sequence: GTGATAGAATTTTCTTATCAC Position: -76 Score: 4.6 Sequence: GTGATAGAAATTATATAATAG Locus tag: SMU.1942c
	SMU.1942c	-98	6	GTGATAGAATTTTCTTATCAC
		-76	4.6	GTGATAGAAATTATATAATAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0381	-75	5	TTGATAGGAATTAATTATTAG
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1680	-41	5	ATGATAAACTAATCTTATGAA
Streptococcus gallolyticus UCN34	GALLO_1845	-122	6	GTGATAAGTTTTATTTATCAC
Streptococcus mitis B6	smi_1945	-99	5.1	GCCATAAAGAAAACCTATCAC
Streptococcus mutans UA159	SMU.1942c	-98	6	GTGATAGAATTTTCTTATCAC
		-76	4.6	GTGATAGAAATTATATAATAG
Streptococcus pyogenes M1 GAS	SPy0317	-75	4.5	TTGATAGGAATCAATTATTAG
Streptococcus thermophilus CNRZ1066	str0296	-98	5.7	GTGATAGTATTTTCTTATCAC
Streptococcus uberis 0140J	SUB0365	-93	4.9	GTGATAGAGAACTATTATCAT
		-71	4.2	GCGATAGTGAATCACTATTAG

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of CmbR regulog to Streptococcus mutans UA159

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --