Propagated regulons of Lactococcus lactis subsp. lactis Il1403
| Type | Regulator | Effector | Pathway | Genes | Sites |
|---|---|---|---|---|---|
| TF | AdcR | Zinc ion, (Zn2+) | Zinc homeostasis | 2 | 2 |
| TF | ArgR | Arginine | Arginine biosynthesis; Arginine degradation | 8 | 22 |
| TF | BirA | Biotin | Biotin biosynthesis | 2 | 2 |
| TF | BusR | Betaine | Betaine utilization | 1 | 1 |
| TF | CcpA | Fructose-1,6-bisphosphate; HPr, phosphocarrier protein | Global catabolite repression | 51 | 71 |
| TF | CcpB | Sugar utilization | 1 | 1 | |
| TF | CmbR | O-acetyl-L-serine | Cysteine metabolism | 10 | 13 |
| TF | CodY | Guanosine triphosphate; Branched-chain amino acids | Amino acid metabolism | 15 | 19 |
| TF | CopR | Copper ion, (Cu2+) | Copper homeostasis | 6 | 7 |
| TF | CtsR | Heat shock | Heat shock response | 3 | 3 |
| TF | FabT | Long-chain acyl-ACP | Fatty acid biosynthesis | 6 | 6 |
| TF | FlpA | Oxygen | Heavy metal resistance | 2 | 2 |
| TF | FlrR | Drug resistance | 2 | 2 | |
| TF | FruR | Fructose-6-phosphate | Fructose utilization | 1 | 5 |
| TF | GlnR | Phosphorylated NtrB, signal histidine kinase | Nitrogen assimilation | 3 | 4 |
| TF | GntR1 | Gluconate | Gluconate utilization | 3 | 3 |
| TF | HomR | O-acetyl-L-serine | Methionine metabolism; Cysteine metabolism | 2 | 2 |
| TF | HrcA | Heat shock | Heat shock response | 3 | 4 |
| TF | MalR | Maltose | Maltose utilization; Maltodextrin utilization | 2 | 3 |
| TF | MleR | L-malate | Malate utilization | 1 | 1 |
| TF | MntR | Manganese ion, (Mn2+) | Manganese homeostasis | 2 | 2 |
| TF | MtaR | Homocysteine | Methionine metabolism | 1 | 1 |
| TF | MurR | N-acetylmuramate-6-phosphate | N-acetylmuramate utilization | 1 | 1 |
| TF | NagR | N-acetylglucosamine-6-phosphate | N-acetylglucosamine utilization | 3 | 4 |
| TF | NmlR | Methylglyoxal; Formaldehyde; Nitric oxide | Carbonyl stress response | 2 | 2 |
| TF | NrdR | Deoxyribonucleotides | Deoxyribonucleotide biosynthesis | 2 | 3 |
| TF | PadR | Ferulic acid; p-Coumaric acid | Phenolic acid stress response | 1 | 1 |
| TF | PerR | Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide | Iron homeostasis; Manganese homeostasis; Oxidative stress response | 4 | 5 |
| TF | PipR | Phage infection protein | 2 | 2 | |
| TF | PurR | 5-phosphoribosyl 1-pyrophosphate | Purine metabolism | 18 | 25 |
| TF | RbsR2 | Ribose | Ribose utilization | 1 | 3 |
| TF | Rex | NADH | Energy metabolism | 11 | 20 |
| TF | TreR (RgrA) | Trehalose-6-phosphate | Trehalose utilization | 2 | 2 |
| TF | UxuR | Glucuronate | Glucuronate utilization | 2 | 2 |
| TF | YxeR | Antibiotic resistance | 1 | 1 | |