Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Rex in Thermosipho melanesiensis BI429

Properties
Regulator type: Transcription factor
TF locus tag: Tmel_1209
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Regulog: Rex - Thermotogales
Statistics of regulated genes:
- Genes 19
- Operons 7
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 114 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -43
Score: 5
Sequence: TcGTGAAAAaTaTaACgt
Position: -29
Score: 4.9
Sequence: acGTtAtttaTTTCACgA
Locus tag: Tmel_0495
Name: TM1420
Funciton: Fe-hydrogenase, thioredoxin subunit, 2Fe-2S cluster binding protein
Locus tag: Tmel_0494
Name: TM1421
Funciton: Fe-hydrogenase, 2Fe-2S iron-sulfur cluster binding protein
Locus tag: Tmel_0493
Name: TM1423
Funciton: predicted protein serine/threonine phosphatase
Locus tag: Tmel_0492
Name: hydC
Funciton: Fe-hydrogenase, gamma subunit, FeS cluster containing
Locus tag: Tmel_0491
Name: hydB
Funciton: Fe-hydrogenase, beta subunit, FeS cluster, FMN, NAD(P)H dehydrogenase activity
Locus tag: Tmel_0490
Name: hydA
Funciton: Fe-hydrogenase, alpha subunit, FeS cluster, hydrogenase activity
Locus tag: Tmel_0489
Name: rex1
Funciton: Redox sensitive transcriptional regulator paralog, Rex family
TM1420
Fe-hydrogenase, thioredoxin subunit, 2Fe-2S cluster binding protein
TM1421
Fe-hydrogenase, 2Fe-2S iron-sulfur cluster binding protein
TM1423
predicted protein serine/threonine phosphatase
hydC
Fe-hydrogenase, gamma subunit, FeS cluster containing
hydB
Fe-hydrogenase, beta subunit, FeS cluster, FMN, NAD(P)H dehydrogenase activity
hydA
Fe-hydrogenase, alpha subunit, FeS cluster, hydrogenase activity
rex1
Redox sensitive transcriptional regulator paralog, Rex family

Position: -95
Score: 4.7
Sequence: ccGTGAAAAaaaTaACgA
Position: -29
Score: 5.1
Sequence: TTGTGAAAATATTCACAG
Locus tag: Tmel_0139
Name: adhA
Funciton: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent
adhA
Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent

Position: -31
Score: 5.2
Sequence: TAGTTAAAAAAATCACAA
Locus tag: Tmel_0141
Name: noxE2
Funciton: NADH oxidase (EC 1.6.99.3)
noxE2
NADH oxidase (EC 1.6.99.3)

Position: -108
Score: 4.7
Sequence: TTGTGAtAtaaTTtACtt
Locus tag: Tmel_1601
Name: hycD
Funciton: NAD-reducing Fe-hydrogenase, subunit HycD (EC 1.12.7.2)
hycD
NAD-reducing Fe-hydrogenase, subunit HycD (EC 1.12.7.2)

Position: -59
Score: 4.9
Sequence: TTGTGAAAAATATATCAT
Locus tag: Tmel_1229
Name: noxE
Funciton: NADH oxidase (EC 1.6.99.3)
noxE
NADH oxidase (EC 1.6.99.3)

Position: -45
Score: 5.2
Sequence: TaGTaAAAtTTTTCACgA
Locus tag: Tmel_1266
Name: gap
Funciton: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Locus tag: Tmel_1265
Name: pgk
Funciton: Phosphoglycerate kinase (EC 2.7.2.3)
Locus tag: Tmel_1264
Name: tpi
Funciton: Triosephosphate isomerase (EC 5.3.1.1)
gap
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
pgk
Phosphoglycerate kinase (EC 2.7.2.3)
tpi
Triosephosphate isomerase (EC 5.3.1.1)

Position: -68
Score: 4.5
Sequence: aaGTGAAttTTTTtACtt
Position: 9
Score: 4.2
Sequence: TTGTGAAAAacaTgtCgA
Locus tag: Tmel_1172
Name: hycA
Funciton: NAD-reducing Fe-hydrogenase, subunit HycA (EC 1.12.7.2)
Locus tag: Tmel_1171
Name: hycB
Funciton: NAD-reducing Fe-hydrogenase, subunit HycB (EC 1.12.7.2)
Locus tag: Tmel_1170
Name: hycC
Funciton: NAD-reducing Fe-hydrogenase, subunit HycC (EC 1.12.7.2)
Locus tag: Tmel_1169
Name: hycE
Funciton: NAD-reducing Fe-hydrogenase, subunit HycE (EC 1.12.7.2)
Locus tag: Tmel_1168
Name: hycF
Funciton: NAD-reducing Fe-hydrogenase, subunit HycF (EC 1.12.7.2)
hycA
NAD-reducing Fe-hydrogenase, subunit HycA (EC 1.12.7.2)
hycB
NAD-reducing Fe-hydrogenase, subunit HycB (EC 1.12.7.2)
hycC
NAD-reducing Fe-hydrogenase, subunit HycC (EC 1.12.7.2)
hycE
NAD-reducing Fe-hydrogenase, subunit HycE (EC 1.12.7.2)
hycF
NAD-reducing Fe-hydrogenase, subunit HycF (EC 1.12.7.2)
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