Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Rex in Thermotoga maritima MSB8

Properties
Regulator type: Transcription factor
TF locus tag: TM0169
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Regulog: Rex - Thermotogales
Statistics of regulated genes:
- Genes 39
- Operons 12
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 114 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -177
Score: 4.9
Sequence: GAGTAAAATATTTCACAA
Locus tag: TM1586
Name: TM1586
Funciton: Putative oxidoreductase, COG0778
Locus tag: TM1585
Name: gckA
Funciton: D-glycerate 2-kinase (EC 2.7.1.-), GK-II family
TM1586
Putative oxidoreductase, COG0778
gckA
D-glycerate 2-kinase (EC 2.7.1.-), GK-II family

Position: -52
Score: 5.5
Sequence: TCGTGAAAAATTTAACAA
Locus tag: TM0423
Name: gldA
Funciton: Glycerol dehydrogenase (EC 1.1.1.6)
gldA
Glycerol dehydrogenase (EC 1.1.1.6)

Position: -47
Score: 5.1
Sequence: TAGTTAAAAAAATAACAA
Locus tag: TM1400
Name: sat
Funciton: Serine aminotransferase (EC 2.6.5.1)
Locus tag: TM1401
Name: hpr
Funciton: Hydroxypyruvate reductase (EC 1.1.1.81)
sat
Serine aminotransferase (EC 2.6.5.1)
hpr
Hydroxypyruvate reductase (EC 1.1.1.81)

Position: -41
Score: 5.1
Sequence: TTGAGATTTTTTTCACAA
Locus tag: TM0983
Name: TM0983
Funciton: conserved hypothetical protein, SirA family
Locus tag: TM0982
Name: TM0982
Funciton: protein of unknown function DUF395 YeeE/YedE
Locus tag: TM0981
Name: TM0981
Funciton: DsrE family protein
Locus tag: TM0980
Name: TM0980
Funciton: uncharacterized protein involved in the oxidation of intracellular sulfur-like protein
Locus tag: TM0979
Name: TM0979
Funciton: DsrH family protein
TM0983
conserved hypothetical protein, SirA family
TM0982
protein of unknown function DUF395 YeeE/YedE
TM0981
DsrE family protein
TM0980
uncharacterized protein involved in the oxidation of intracellular sulfur-like protein
TM0979
DsrH family protein

Position: 24
Score: 5.3
Sequence: TTGAGAAATTTATCACAA
Locus tag: TM0201
Name: hycD
Funciton: NAD-reducing Fe-hydrogenase, subunit HycD (EC 1.12.7.2)
hycD
NAD-reducing Fe-hydrogenase, subunit HycD (EC 1.12.7.2)

Position: -104
Score: 5.1
Sequence: TaGTtAtttTTTTCACgA
Locus tag: TM0686
Name: dnaX
Funciton: DNA polymerase III subunits gamma and tau
Locus tag: TM0687
Name: TM0687
Funciton: conserved probable DNA binding protein, similar to YbaB family
Locus tag: TM0688
Name: gap
Funciton: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Locus tag: TM0689
Name: pgk
Funciton: Phosphoglycerate kinase (EC 2.7.2.3)
dnaX
DNA polymerase III subunits gamma and tau
TM0687
conserved probable DNA binding protein, similar to YbaB family
gap
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
pgk
Phosphoglycerate kinase (EC 2.7.2.3)

Position: -32
Score: 5
Sequence: TCGTGAAAAATTTCTCTT
Locus tag: TM0379
Name: noxE
Funciton: NADH oxidase (EC 1.6.99.3)
noxE
NADH oxidase (EC 1.6.99.3)

Position: -40
Score: 4.9
Sequence: ATGATAAAATTATCACAA
Locus tag: TM1814
Name: cas6
Funciton: CRISPR/Cas system-associated RAMP superfamily protein Cas6
Locus tag: TM1813
Name: null
Funciton: hypothetical protein
Locus tag: TM1812
Name: csx1
Funciton: CRISPR/Cas system-associated protein Csx1
Locus tag: TM1811
Name: cas10
Funciton: CRISPR/Cas system-associated protein Cas10
Locus tag: TM1810
Name: csm2
Funciton: CRISPR/Cas system-associated protein Csm2
Locus tag: TM1809
Name: csm3
Funciton: CRISPR/Cas system-associated RAMP superfamily protein Csm3
Locus tag: TM1808
Name: csm4
Funciton: CRISPR/Cas system-associated RAMP superfamily protein Csm4
Locus tag: TM1807
Name: csm5
Funciton: CRISPR/Cas system-associated RAMP superfamily protein Csm5
Locus tag: TM1806
Name: TM1806
Funciton: hypothetical protein
cas6
CRISPR/Cas system-associated RAMP superfamily protein Cas6
hypothetical protein
csx1
CRISPR/Cas system-associated protein Csx1
cas10
CRISPR/Cas system-associated protein Cas10
csm2
CRISPR/Cas system-associated protein Csm2
csm3
CRISPR/Cas system-associated RAMP superfamily protein Csm3
csm4
CRISPR/Cas system-associated RAMP superfamily protein Csm4
csm5
CRISPR/Cas system-associated RAMP superfamily protein Csm5
TM1806
hypothetical protein

Position: -30
Score: 4.6
Sequence: TTGTTATAATAGTAACAA
Locus tag: TM0179
Name: TM0179
Funciton: hypothetical protein
TM0179
hypothetical protein

Position: -45
Score: 5
Sequence: TaGTGAAAAaTaTaACgt
Locus tag: TM1420
Name: TM1420
Funciton: Fe-hydrogenase, thioredoxin subunit, 2Fe-2S cluster binding protein
Locus tag: TM1421
Name: TM1421
Funciton: Fe-hydrogenase, 2Fe-2S iron-sulfur cluster binding protein
Locus tag: TM1422
Name: TM1421
Funciton: Fe-hydrogenase, 2Fe-2S iron-sulfur cluster binding protein
Locus tag: TM1423
Name: TM1423
Funciton: predicted protein serine/threonine phosphatase
Locus tag: TM1424
Name: hydC
Funciton: Fe-hydrogenase, gamma subunit, FeS cluster containing
Locus tag: TM1425
Name: hydB
Funciton: Fe-hydrogenase, beta subunit, FeS cluster, FMN, NAD(P)H dehydrogenase activity
Locus tag: TM1426
Name: hydA
Funciton: Fe-hydrogenase, alpha subunit, FeS cluster, hydrogenase activity
Locus tag: TM1427
Name: rex1
Funciton: Redox sensitive transcriptional regulator paralog, Rex family
TM1420
Fe-hydrogenase, thioredoxin subunit, 2Fe-2S cluster binding protein
TM1421
Fe-hydrogenase, 2Fe-2S iron-sulfur cluster binding protein
TM1421
Fe-hydrogenase, 2Fe-2S iron-sulfur cluster binding protein
TM1423
predicted protein serine/threonine phosphatase
hydC
Fe-hydrogenase, gamma subunit, FeS cluster containing
hydB
Fe-hydrogenase, beta subunit, FeS cluster, FMN, NAD(P)H dehydrogenase activity
hydA
Fe-hydrogenase, alpha subunit, FeS cluster, hydrogenase activity
rex1
Redox sensitive transcriptional regulator paralog, Rex family

Position: -499
Score: 5.3
Sequence: TTGTGAAATTTTTGACGA
Locus tag: TM0228
Name: hycF
Funciton: NAD-reducing Fe-hydrogenase, subunit HycF (EC 1.12.7.2)
hycF
NAD-reducing Fe-hydrogenase, subunit HycF (EC 1.12.7.2)

Position: -27
Score: 4.3
Sequence: aTGTGAAAAaaaTatCAg
Position: -2
Score: 5
Sequence: TTGTGAAAAaaTTCcCgA
Locus tag: TM0012
Name: hycA
Funciton: NAD-reducing Fe-hydrogenase, subunit HycA (EC 1.12.7.2)
Locus tag: TM0011
Name: hycB
Funciton: NAD-reducing Fe-hydrogenase, subunit HycB (EC 1.12.7.2)
Locus tag: TM0010
Name: hycC
Funciton: NAD-reducing Fe-hydrogenase, subunit HycC (EC 1.12.7.2)
Locus tag: TM0009
Name: TM0009
Funciton: rubrerythrin
hycA
NAD-reducing Fe-hydrogenase, subunit HycA (EC 1.12.7.2)
hycB
NAD-reducing Fe-hydrogenase, subunit HycB (EC 1.12.7.2)
hycC
NAD-reducing Fe-hydrogenase, subunit HycC (EC 1.12.7.2)
TM0009
rubrerythrin
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