Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of HypR2 in Silicibacter TM1040

Properties
Regulator type: Transcription factor
TF locus tag: TM1040_3324
Regulator family: GntR/Others
Regulation mode:
Biological process: Proline and 4-hydrohyproline utilization
Effector: 4-hydroxyproline
Regulog: HypR2 - Rhodobacterales
Statistics of regulated genes:
- Genes 7
- Operons 4
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 17 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -127
Score: 4.8
Sequence: TTTTGGATACGTTA
Position: -41
Score: 4.3
Sequence: TGATGTATCCGATA
Locus tag: TM1040_3323
Name: hypS
Funciton: Putative L-lactate/Malate dehydrogenase
hypS
Putative L-lactate/Malate dehydrogenase

Position: -55
Score: 4.8
Sequence: ATATGTATACATTA
Locus tag: TM1040_3325
Name: hypH
Funciton: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
hypH
Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible

Position: -158
Score: 5.3
Sequence: TTTTGGATACAAAA
Locus tag: TM1040_3198
Name: hypD
Funciton: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
Locus tag: TM1040_3199
Name: hypE
Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
Locus tag: TM1040_3200
Name: hypO
Funciton: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
Locus tag: TM1040_3201
Name: hypY
Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
hypD
1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
hypE
Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
hypO
D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
hypY
Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)

Position: -129
Score: 4.3
Sequence: TATCGGATACATCA
Position: -43
Score: 4.8
Sequence: TAACGTATCCAAAA
Locus tag: TM1040_3324
Name: hypR2
Funciton: Predicted regulator for proline and hydrohyproline utilization, GntR family
hypR2
Predicted regulator for proline and hydrohyproline utilization, GntR family
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