Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CblR in Natronomonas pharaonis DSM 2160

Properties
Regulator type: Transcription factor
TF locus tag:
Regulator family:
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector:
Regulog: CblR - Halobacteriales
Statistics of regulated genes:
- Genes 27
- Operons 9
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 91 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -45
Score: 4.6
Sequence: TTGTCAATCACGGTTGTATT
Position: -25
Score: 4
Sequence: AGAACAACCGGAGTTTATCA
Locus tag: NP1092A
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: NP1090A
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: NP1088A
Name: cbiJ
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
NP1092A
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
NP1090A
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
NP1088A
cbiJ
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Position: -117
Score: 5.4
Sequence: TAATCAAGTATAGTTGTATT
Position: -97
Score: 4.4
Sequence: ACAGCAATTCGGCTTGTACA
Position: -33
Score: 4.1
Sequence: GGTTCAAGTACACTTGTCCA
Locus tag: NP0736A
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: NP0738A
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
NP0736A
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
NP0738A
cbiA
Cobyrinic acid A,C-diamide synthase
Position: -47
Score: 4.4
Sequence: TGTACAAGCCGAATTGCTGT
Position: -27
Score: 5.4
Sequence: AATACAACTATACTTGATTA
Locus tag: NP0734A
Name: cbiD-II
Funciton: B12 biosynthesis-related protein, possible CbiD equivalent
NP0734A
cbiD-II
B12 biosynthesis-related protein, possible CbiD equivalent
Position: -21
Score: 4.2
Sequence: AAACCAAGCCCAGTTGCAGC
Locus tag: NP3816A
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: NP3818A
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
NP3816A
btuC
Vitamin B12 ABC transporter, permease component BtuC
NP3818A
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
Position: -137
Score: 5
Sequence: AAATCAAGTTCATTTGTACT
Position: -117
Score: 4.3
Sequence: ACACCAATTTTATTTGGAAA
Locus tag: NP6162A
Name: nrdR
Funciton: Ribonucleotide reductase transcriptional regulator NrdR
Locus tag: NP6164A
Name: null
Funciton: hypothetical protein
Locus tag: NP6166A
Name: nrdB2
Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Locus tag: NP6168A
Name: nrdA2
Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
NP6162A
nrdR
Ribonucleotide reductase transcriptional regulator NrdR
NP6164A
hypothetical protein
NP6166A
nrdB2
Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
NP6168A
nrdA2
Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Position: -101
Score: 5.2
Sequence: ACAACAAGCACAATTGTTAT
Locus tag: NP1116A
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: NP1114A
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: NP1112A
Name: VNG1558H
Funciton: conserved cobalamin operon protein
Locus tag: NP1110A
Name: VNG1559H
Funciton: conserved cobalamin operon protein
Locus tag: NP1108A
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: NP1106A
Name: VNG1562H
Funciton: conserved cobalamin operon protein
NP1116A
cbiH
Cobalt-precorrin-3b C17-methyltransferase
NP1114A
cbiH
Cobalt-precorrin-3b C17-methyltransferase
NP1112A
VNG1558H
conserved cobalamin operon protein
NP1110A
VNG1559H
conserved cobalamin operon protein
NP1108A
cbiK
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
NP1106A
VNG1562H
conserved cobalamin operon protein
Position: -46
Score: 5.3
Sequence: AGCACAACCAAAATTGTTTT
Locus tag: NP1124A
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: NP1122A
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: NP1120A
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: NP1118A
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
NP1124A
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
NP1122A
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
NP1120A
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
NP1118A
cbiG
Cobalamin biosynthesis protein CbiG
Position: -57
Score: 4.2
Sequence: GCTGCAACTGGGCTTGGTTT
Locus tag: NP3814A
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
NP3814A
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
Position: -29
Score: 4
Sequence: TGATAAACTCCGGTTGTTCT
Position: -9
Score: 4.6
Sequence: AATACAACCGTGATTGACAA
Locus tag: NP1094A
Name: chlID
Funciton: ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis
Locus tag: NP1096A
Name: cbtB
Funciton: Cobalt transporter subunit CbtB, putative
Locus tag: NP1098A
Name: cbtA
Funciton: Predicted cobalt transporter CbtA
Locus tag: NP1100A
Name: cbiX_2
Funciton: conserved cobalamin cluster protein CbiX 2 (probable ferredoxin-like iron-sulfur protein)
NP1094A
chlID
ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis
NP1096A
cbtB
Cobalt transporter subunit CbtB, putative
NP1098A
cbtA
Predicted cobalt transporter CbtA
NP1100A
cbiX_2
conserved cobalamin cluster protein CbiX 2 (probable ferredoxin-like iron-sulfur protein)
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