Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CblR in Halorubrum lacusprofundi ATCC 49239

Properties
Regulator type: Transcription factor
TF locus tag:
Regulator family:
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector:
Regulog: CblR - Halobacteriales
Statistics of regulated genes:
- Genes 24
- Operons 9
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 91 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -45
Score: 5.4
Sequence: AAATCAACCATGGTTGTAGT
Locus tag: Hlac_3461
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Hlac_3460
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Hlac_3459
Name: cbiJ
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Hlac_3461
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
Hlac_3460
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Hlac_3459
cbiJ
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Position: -33
Score: 4.4
Sequence: AGATAAAGTATAGTTGAACT
Locus tag: Hlac_3458
Name: cbiD-II
Funciton: B12 biosynthesis-related protein, possible CbiD equivalent
Hlac_3458
cbiD-II
B12 biosynthesis-related protein, possible CbiD equivalent
Position: -24
Score: 4.3
Sequence: ACTACAAGTTTTGTTGGAGA
Locus tag: Hlac_0881
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Hlac_0882
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Hlac_0881
btuC
Vitamin B12 ABC transporter, permease component BtuC
Hlac_0882
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
Position: -136
Score: 5.5
Sequence: AATACAAGTTTAGTTGTGTT
Locus tag: Hlac_2946
Name: nrdR
Funciton: Ribonucleotide reductase transcriptional regulator NrdR
Locus tag: Hlac_2945
Name: nrdB2
Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Locus tag: Hlac_2944
Name: nrdA2
Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Hlac_2946
nrdR
Ribonucleotide reductase transcriptional regulator NrdR
Hlac_2945
nrdB2
Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Hlac_2944
nrdA2
Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Position: -229
Score: 4.9
Sequence: TTTACAAGCTCAGTTGTGTT
Locus tag: Hlac_3464
Name: cbtA
Funciton: Predicted cobalt transporter CbtA
Locus tag: Hlac_3465
Name: cbiX_2
Funciton: conserved cobalamin cluster protein CbiX 2 (probable ferredoxin-like iron-sulfur protein)
Hlac_3464
cbtA
Predicted cobalt transporter CbtA
Hlac_3465
cbiX_2
conserved cobalamin cluster protein CbiX 2 (probable ferredoxin-like iron-sulfur protein)
Position: -58
Score: 4.3
Sequence: TCTCCAACAAAACTTGTAGT
Locus tag: Hlac_0880
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Hlac_0880
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
Position: -46
Score: 5
Sequence: AGCTCAACCAAAATTGTTTT
Locus tag: Hlac_3478
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Hlac_3477
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Hlac_3476
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Hlac_3475
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: Hlac_3474
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Hlac_3473
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Hlac_3472
Name: VNG1558H
Funciton: conserved cobalamin operon protein
Locus tag: Hlac_3471
Name: VNG1559H
Funciton: conserved cobalamin operon protein
Locus tag: Hlac_3470
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: Hlac_3469
Name: VNG1562H
Funciton: conserved cobalamin operon protein
Hlac_3478
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Hlac_3477
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Hlac_3476
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Hlac_3475
cbiG
Cobalamin biosynthesis protein CbiG
Hlac_3474
cbiH
Cobalt-precorrin-3b C17-methyltransferase
Hlac_3473
cbiH
Cobalt-precorrin-3b C17-methyltransferase
Hlac_3472
VNG1558H
conserved cobalamin operon protein
Hlac_3471
VNG1559H
conserved cobalamin operon protein
Hlac_3470
cbiK
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Hlac_3469
VNG1562H
conserved cobalamin operon protein
Position: -39
Score: 4.9
Sequence: TTTACAAGCTCAGTTGTGTT
Locus tag: Hlac_3463
Name: cbtB
Funciton: Cobalt transporter subunit CbtB, putative
Hlac_3463
cbtB
Cobalt transporter subunit CbtB, putative
Position: -9
Score: 5.4
Sequence: ACTACAACCATGGTTGATTT
Locus tag: Hlac_3462
Name: chlID
Funciton: ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis
Hlac_3462
chlID
ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis
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