Regulon of CblR in Halorubrum lacusprofundi ATCC 49239
Regulator type: | Transcription factor |
TF locus tag: | |
Regulator family: | |
Regulation mode: | |
Biological process: | Cobalamin biosynthesis |
Effector: | |
Regulog: | CblR - Halobacteriales |
Statistics of regulated genes: | |
- Genes | 24 |
- Operons | 9 |
Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |

Member of regulog collections
- By taxonomy - Halobacteriales
- By trascription factor - CblR
- By pathway - Cobalamin biosynthesis
Locus Tag | Name | Function | |
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Position: -45
Score: 5.4 Sequence: AAATCAACCATGGTTGTAGT
Locus tag: Hlac_3461
Name: cobN Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Hlac_3460
Name: cbiC Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Hlac_3459
Name: cbiJ Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
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cobN
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CobN component of cobalt chelatase involved in B12 biosynthesis
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cbiC
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Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
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cbiJ
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Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
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Position: -33
Score: 4.4 Sequence: AGATAAAGTATAGTTGAACT
Locus tag: Hlac_3458
Name: cbiD-II Funciton: B12 biosynthesis-related protein, possible CbiD equivalent |
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cbiD-II
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B12 biosynthesis-related protein, possible CbiD equivalent
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Position: -24
Score: 4.3 Sequence: ACTACAAGTTTTGTTGGAGA
Locus tag: Hlac_0881
Name: btuC Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Hlac_0882
Name: btuD Funciton: Vitamin B12 ABC transporter, ATPase component BtuD |
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btuC
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Vitamin B12 ABC transporter, permease component BtuC
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btuD
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Vitamin B12 ABC transporter, ATPase component BtuD
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Position: -136
Score: 5.5 Sequence: AATACAAGTTTAGTTGTGTT
Locus tag: Hlac_2946
Name: nrdR Funciton: Ribonucleotide reductase transcriptional regulator NrdR
Locus tag: Hlac_2945
Name: nrdB2 Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Locus tag: Hlac_2944
Name: nrdA2 Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1) |
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nrdR
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Ribonucleotide reductase transcriptional regulator NrdR
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nrdB2
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Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
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nrdA2
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Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
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Position: -229
Score: 4.9 Sequence: TTTACAAGCTCAGTTGTGTT
Locus tag: Hlac_3464
Name: cbtA Funciton: Predicted cobalt transporter CbtA
Locus tag: Hlac_3465
Name: cbiX_2 Funciton: conserved cobalamin cluster protein CbiX 2 (probable ferredoxin-like iron-sulfur protein) |
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cbtA
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Predicted cobalt transporter CbtA
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cbiX_2
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conserved cobalamin cluster protein CbiX 2 (probable ferredoxin-like iron-sulfur protein)
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Position: -58
Score: 4.3 Sequence: TCTCCAACAAAACTTGTAGT
Locus tag: Hlac_0880
Name: btuF Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF |
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btuF
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Vitamin B12 ABC transporter, B12-binding component BtuF
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Position: -46
Score: 5 Sequence: AGCTCAACCAAAATTGTTTT
Locus tag: Hlac_3478
Name: cbiT Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Hlac_3477
Name: cbiL Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Hlac_3476
Name: cbiF Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Hlac_3475
Name: cbiG Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: Hlac_3474
Name: cbiH Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Hlac_3473
Name: cbiH Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Hlac_3472
Name: VNG1558H Funciton: conserved cobalamin operon protein
Locus tag: Hlac_3471
Name: VNG1559H Funciton: conserved cobalamin operon protein
Locus tag: Hlac_3470
Name: cbiK Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: Hlac_3469
Name: VNG1562H Funciton: conserved cobalamin operon protein |
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cbiT
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Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
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cbiL
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Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
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cbiF
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Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
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cbiG
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Cobalamin biosynthesis protein CbiG
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cbiH
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Cobalt-precorrin-3b C17-methyltransferase
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cbiH
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Cobalt-precorrin-3b C17-methyltransferase
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VNG1558H
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conserved cobalamin operon protein
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VNG1559H
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conserved cobalamin operon protein
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cbiK
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Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
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VNG1562H
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conserved cobalamin operon protein
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Position: -39
Score: 4.9 Sequence: TTTACAAGCTCAGTTGTGTT
Locus tag: Hlac_3463
Name: cbtB Funciton: Cobalt transporter subunit CbtB, putative |
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cbtB
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Cobalt transporter subunit CbtB, putative
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Position: -9
Score: 5.4 Sequence: ACTACAACCATGGTTGATTT
Locus tag: Hlac_3462
Name: chlID Funciton: ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis |
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chlID
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ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |