Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CblR in Halobacterium sp. NRC-1

Properties
Regulator type: Transcription factor
TF locus tag:
Regulator family:
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector:
Regulog: CblR - Halobacteriales
Statistics of regulated genes:
- Genes 32
- Operons 7
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 91 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -45
Score: 5.6
Sequence: AATACAATCAAAATTGTTTT
Locus tag: VNG1550G
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: VNG1551G
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: VNG1553G
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: VNG1554G
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: VNG1555G
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: VNG1557G
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: VNG1558H
Name: VNG1558H
Funciton: conserved cobalamin operon protein
Locus tag: VNG1559H
Name: VNG1559H
Funciton: conserved cobalamin operon protein
Locus tag: VNG1561Cm
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: VNG1562H
Name: VNG1562H
Funciton: conserved cobalamin operon protein
Locus tag: VNG1564H
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
VNG1550G
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
VNG1551G
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
VNG1553G
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
VNG1554G
cbiG
Cobalamin biosynthesis protein CbiG
VNG1555G
cbiH
Cobalt-precorrin-3b C17-methyltransferase
VNG1557G
cbiH
Cobalt-precorrin-3b C17-methyltransferase
VNG1558H
VNG1558H
conserved cobalamin operon protein
VNG1559H
VNG1559H
conserved cobalamin operon protein
VNG1561Cm
cbiK
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
VNG1562H
VNG1562H
conserved cobalamin operon protein
VNG1564H
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Position: -240
Score: 5.5
Sequence: AAATCAACCATAGTTGTAAT
Locus tag: VNG1566G
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: VNG1567G
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: VNG1568G
Name: cbiJ
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
VNG1566G
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
VNG1567G
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
VNG1568G
cbiJ
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Position: -44
Score: 4.8
Sequence: TATGCAACCACAGTTGGGTT
Locus tag: VNG1570H
Name: cbiD-II
Funciton: B12 biosynthesis-related protein, possible CbiD equivalent
VNG1570H
cbiD-II
B12 biosynthesis-related protein, possible CbiD equivalent
Position: -153
Score: 4.9
Sequence: TGATCAACTTAGATTGTACT
Position: -133
Score: 4.6
Sequence: TCTACAAGTTTAGTTGGTAA
Locus tag: VNG2384G
Name: nrdA1
Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Locus tag: VNG2383G
Name: nrdB1
Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
VNG2384G
nrdA1
Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
VNG2383G
nrdB1
Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Position: -69
Score: 5.2
Sequence: AATACAAATTCAGTTGTTCT
Locus tag: VNG1635G
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: VNG1634G
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: VNG1632G
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: VNG1631G
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
VNG1635G
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
VNG1634G
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
VNG1632G
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
VNG1631G
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
Position: -9
Score: 5.5
Sequence: ATTACAACTATGGTTGATTT
Locus tag: VNG1565G
Name: chlID
Funciton: ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis
VNG1565G
chlID
ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis
Position: -219
Score: 4.8
Sequence: AACCCAACTGTGGTTGCATA
Locus tag: VNG1572C
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: VNG1573G
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: VNG1574G
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: VNG1576G
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: VNG1577C
Name: VNG1577C
Funciton: conserved cobalamine operon protein, HAD family hydrolase
Locus tag: VNG1578H
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: VNG1580H
Name: cobS
Funciton: Cobalamin synthase
Locus tag: VNG1581C
Name: cobY
Funciton: Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
Locus tag: VNG1582G
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: VNG1583C
Name: cbiZ
Funciton: Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
VNG1572C
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
VNG1573G
cbiA
Cobyrinic acid A,C-diamide synthase
VNG1574G
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
VNG1576G
cbiP
Cobyric acid synthase
VNG1577C
VNG1577C
conserved cobalamine operon protein, HAD family hydrolase
VNG1578H
cbiB
Adenosylcobinamide-phosphate synthase
VNG1580H
cobS
Cobalamin synthase
VNG1581C
cobY
Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
VNG1582G
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
VNG1583C
cbiZ
Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD
© 2009-2020 RegPrecise