Regulon of CblR in Halobacterium salinarum R1
Regulator type: | Transcription factor |
TF locus tag: | |
Regulator family: | |
Regulation mode: | |
Biological process: | Cobalamin biosynthesis |
Effector: | |
Regulog: | CblR - Halobacteriales |
Statistics of regulated genes: | |
- Genes | 32 |
- Operons | 7 |
Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |

Member of regulog collections
- By taxonomy - Halobacteriales
- By trascription factor - CblR
- By pathway - Cobalamin biosynthesis
Locus Tag | Name | Function | |
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Position: -45
Score: 5.5 Sequence: AAATCAACCATAGTTGTAAT
Locus tag: OE3230F
Name: cobN Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: OE3237F
Name: cbiC Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: OE3238F
Name: cbiJ Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
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cobN
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CobN component of cobalt chelatase involved in B12 biosynthesis
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cbiC
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Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
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cbiJ
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Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
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Position: -44
Score: 4.8 Sequence: TATGCAACCACAGTTGGGTT
Locus tag: OE3239R
Name: cbiD-II Funciton: B12 biosynthesis-related protein, possible CbiD equivalent |
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cbiD-II
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B12 biosynthesis-related protein, possible CbiD equivalent
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Position: -153
Score: 4.9 Sequence: TGATCAACTTAGATTGTACT
Position: -133
Score: 4.6 Sequence: TCTACAAGTTTAGTTGGTAA
Locus tag: OE4346R
Name: nrdA1 Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Locus tag: OE4345R
Name: nrdB1 Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1) |
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nrdA1
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Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
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nrdB1
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Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
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Position: -69
Score: 5.2 Sequence: AATACAAATTCAGTTGTTCT
Locus tag: OE3319R
Name: cbiM Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: OE3318R
Name: cbiN Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: OE3317R
Name: cbiQ Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: OE3315R
Name: cbiO Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter |
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cbiM
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Substrate-specific component CbiM of cobalt ECF transporter
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cbiN
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Additional substrate-specific component CbiN of cobalt ECF transporter
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cbiQ
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Transmembrane component CbiQ of energizing module of cobalt ECF transporter
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cbiO
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ATPase component CbiO of energizing module of cobalt ECF transporter
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Position: -120
Score: 4.8 Sequence: AACCCAACTGTGGTTGCATA
Locus tag: OE3242F
Name: cobT Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: OE3243F
Name: cbiA Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: OE3245F
Name: btuR Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: OE3246F
Name: cbiP Funciton: Cobyric acid synthase
Locus tag: OE3249F
Name: VNG1577C Funciton: conserved cobalamine operon protein, HAD family hydrolase
Locus tag: OE3253F
Name: cbiB Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: OE3255F
Name: cobS Funciton: Cobalamin synthase
Locus tag: OE3257F
Name: cobY Funciton: Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
Locus tag: OE3259F
Name: cobD Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: OE3261F
Name: cbiZ Funciton: Adenosylcobinamide amidohydrolase (EC 3.5.1.90) |
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cobT
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Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
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cbiA
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Cobyrinic acid A,C-diamide synthase
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btuR
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Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
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cbiP
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Cobyric acid synthase
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VNG1577C
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conserved cobalamine operon protein, HAD family hydrolase
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cbiB
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Adenosylcobinamide-phosphate synthase
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cobS
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Cobalamin synthase
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cobY
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Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
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cobD
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L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
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cbiZ
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Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
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Position: -45
Score: 5.6 Sequence: AATACAATCAAAATTGTTTT
Locus tag: OE3207F
Name: cbiT Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: OE3209F
Name: cbiL Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: OE3212F
Name: cbiF Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: OE3213F
Name: cbiG Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: OE3214F
Name: cbiH Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: OE3216F
Name: cbiH Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: OE3219F
Name: VNG1558H Funciton: conserved cobalamin operon protein
Locus tag: OE3218F
Name: VNG1559H Funciton: conserved cobalamin operon protein
Locus tag: OE3221F
Name: cbiK Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: OE3224F
Name: VNG1562H Funciton: conserved cobalamin operon protein
Locus tag: OE3227F
Name: cobT Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
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cbiT
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Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
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cbiL
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Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
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cbiF
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Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
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cbiG
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Cobalamin biosynthesis protein CbiG
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cbiH
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Cobalt-precorrin-3b C17-methyltransferase
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cbiH
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Cobalt-precorrin-3b C17-methyltransferase
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VNG1558H
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conserved cobalamin operon protein
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VNG1559H
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conserved cobalamin operon protein
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cbiK
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Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
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VNG1562H
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conserved cobalamin operon protein
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cobT
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Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
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Position: -9
Score: 5.5 Sequence: ATTACAACTATGGTTGATTT
Locus tag: OE3229R
Name: chlID Funciton: ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis |
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chlID
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ChlI component of cobalt chelatase involved in B12 biosynthesis / ChlD component of cobalt chelatase involved in B12 biosynthesis
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |